Heart failure trials in United States
387 trials · From ClinicalTrials.gov, checked 12 November 2026. Ask the study team whether a trial fits you.
- No phaseNot yet taking people in United StatesMethamphetamine Use Disorder Support in Heart Failure Pilot Study
- Where
- Los Angeles
- Age
- 18 years and over
- People
- 50
- Run by
- University of Southern California
See details and how to joinNCT07211724 - No phaseTaking peopleThe Salt Study for Heart Failure
- Where
- New Brunswick
- Age
- 18 years and over
- People
- 500
- Run by
- Maya Guglin, MD
See details and how to joinNCT07560592 - No phaseTaking peopleDRAIN: DRainage in Acute Decompensated Heart faIlure With Pleural effusioNs
- Where
- Albany
- Age
- 18 years and over
- People
- 216
- Run by
- Albany Medical College
See details and how to joinNCT07419360 - No phaseTaking peopleCardiovascular Health Improvement Project
- Where
- Ann Arbor
- People
- 15,000
- Run by
- University of Michigan
See details and how to joinNCT02306200 - No phaseTaking peopleDeveloping a Digital Aid to Improve ICD Decisions
- Where
- Greenville, San Francisco
- Age
- 60 years and over
- People
- 600
- Run by
- Stanford University
See details and how to joinNCT07084142 - Phase 1Taking peopleNovel Approaches for Improving Vascular Function in Veterans With HFpEF
- Where
- Salt Lake City
- Age
- 18 years and over
- People
- 90
- Run by
- VA Office of Research and Development
See details and how to joinNCT06312748 - No phaseTaking peopleMuscle Blood Flow Regulation in HFpEF
- Where
- Salt Lake City
- Age
- 18 years and over
- People
- 35
- Run by
- VA Office of Research and Development
See details and how to joinNCT05115890 - Phase 2Taking peopleSGLT2i and KNO3 in HFpEF - The SAK HFpEF Trial
- Where
- Philadelphia
- Age
- 18 years and over
- People
- 53
- Run by
- University of Pennsylvania
See details and how to joinNCT05138575 - No phaseTaking peopleA Study of Paramedic HF Management
- Where
- Rochester
- Age
- 18 years and over
- People
- 75
- Run by
- Mayo Clinic
See details and how to joinNCT06874556 - No phaseTaking peoplePromoting Well-being and Health in Heart Failure
- Where
- Boston
- Age
- 18 years and over
- People
- 280
- Run by
- Massachusetts General Hospital
See details and how to joinNCT04829617 - Phase 2Taking peopleThe EFfect of FinErenone in Kidney TransplantiOn Recipients: The EFFEKTOR Study
- Where
- Chapel Hill
- Age
- 18 years and over
- People
- 100
- Run by
- University of North Carolina, Chapel Hill
See details and how to joinNCT06059664 - No phaseTaking peopleExercise Testing After Preeclampsia
- Where
- Nashville
- Age
- 18 years and over
- People
- 500
- Run by
- Vanderbilt University Medical Center
See details and how to joinNCT06741436 - No phaseTaking peopleThe EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR
- Where
- Albany, Ann Arbor, Augusta, Baltimore, Boston, Browns Mills, Buffalo, Charlottesville, Chicago, Cincinnati, Cleveland, Columbus, Danville, Dayton, Delray Beach, Downers Grove, Edison, Gilbert, Henrico, Houma, Houston, Indianapolis, Lancaster, Littleton, Long Beach, Los Angeles, Marietta, Mechanicsburg, Memphis, Miami, Milwaukee, Naperville, Nashville, Newark, New Orleans, New York, Norfolk, Orlando, Palm Beach, Philadelphia, Phoenix, Pittsburgh, Portland, Poughkeepsie, Redwood City, Richmond, Roanoke, Rochester, Royal Oak, Saginaw, Saint Cloud, Salt Lake City, San Diego, San Francisco, Sioux Falls, Springfield, St Louis, Tallahassee, Tampa, Tucson, Tulsa, Urbana, Washington D.C., Wynnewood
- Age
- 18 years and over
- People
- 300 worldwide
- Run by
- Cardiac Dimensions, Inc.
See details and how to joinNCT03142152 - No phaseTaking peopleObservational Study of Patients Undergoing Diagnostic Right Heart Catheterization
- Where
- Boulder
- Age
- 18 years and over
- People
- 50
- Run by
- HemoCept Inc.
See details and how to joinNCT07224906 - No phaseTaking peopleSmartphone Twelve-Lead ECG Utility In ST-Elevation Myocardial Infarction II
- Where
- Murray, Rochester
- Age
- 18 years and over
- People
- 1,000 worldwide
- Run by
- AliveCor
See details and how to joinNCT06271577 - Phase 4Taking peopleUrine Sodium-Driven Diuretic Adjustment Strategy in Acute Decompensated Heart Failure
- Where
- Lakeland
- Age
- 18 years and over
- People
- 600
- Run by
- Lakeland Regional Health Systems, Inc.
See details and how to joinNCT07263035 - Early phase 1Taking peopleSGLT2 Inhibitors, Ketones, and Cardiovascular Benefit Research Plan
- Where
- San Antonio
- Age
- 18 years to 80 years
- People
- 30
- Run by
- The University of Texas Health Science Center at San Antonio
See details and how to joinNCT05057806 - No phaseEnrolling by invitationImpact of Yoga on Cognitive Function
- Where
- Auburn
- Age
- 55 years to 70 years
- People
- 24
- Run by
- Auburn University
See details and how to joinNCT06434168 - No phaseTaking peopleCardioMEMS HF System Coverage With Evidence Development Study
- Where
- Pleasanton
- Age
- 18 years and over
- People
- 1,000
- Run by
- Abbott Medical Devices
See details and how to joinNCT06779552 - No phaseTaking peopleFeasibility of the SCD in Cardiorenal Syndrome Patients Awaiting LVAD
- Where
- Ann Arbor
- Age
- 18 years and over
- People
- 20
- Run by
- SeaStar Medical
See details and how to joinNCT03836482 - No phaseTaking peopleWhole Exome Sequencing in Finding Causative Variants in Germline DNA Samples From Patients With Congestive Heart Failure Receiving Therapy for Breast Cancer
- Where
- Boston
- People
- 162
- Run by
- National Cancer Institute (NCI)
See details and how to joinNCT02610426 - No phaseEnrolling by invitationSpeech-to-text Tool for Heart Failure Patient-Reported Data
- Where
- Palo Alto
- Age
- 18 years and over
- People
- 100
- Run by
- Stanford University
See details and how to joinNCT07217366 - No phaseTaking peopleForge AHEAD: Feasibility of Yoga to Improve Cognitive Function
- Where
- Auburn
- Age
- 55 years and over
- People
- 20
- Run by
- Auburn University
See details and how to joinNCT07489105 - No phaseTaking peoplePrecision Rehabilitation for Veterans With (HFpEF)
- Where
- Columbia
- Age
- 18 years and over
- People
- 4
- Run by
- Columbia VA Health Care System
See details and how to joinNCT07493915 - Phase 3Taking peopleSotagliflozin to Slow Kidney Function Decline in Persons With Type 1 Diabetes and Diabetic Kidney Disease
- Where
- Aurora, Boston, Chicago, Cleveland, Dallas, Orlando, Portland, Seattle, Spokane, Stanford, St Louis, Syracuse, The Bronx
- Age
- 18 years to 75 years
- People
- 150 worldwide
- Run by
- Alessandro Doria
See details and how to joinNCT06217302