Heart failure trials in United States

In United States 387 Also abroad 1266

387 trials · From ClinicalTrials.gov, checked 12 November 2026. Ask the study team whether a trial fits you.

No phaseTaking people
CALM Study: Cardiomems Assisted Lvad Management
Where
Plano
Age
21 years to 85 years
People
40
Run by
Baylor Research Institute
See details and how to joinNCT07096544
No phaseTaking people
Cardiac point-of Care Ultrasound Training Pathway for Emergency Department Advanced Practice Providers
Where
Durham
Age
18 years and over
People
75
Run by
Duke University
See details and how to joinNCT07159269
Phase 2Taking people
Matching Perfusion and Metabolic Activity in HFpEF
Where
Philadelphia
Age
18 years and over
People
53
Run by
University of Pennsylvania
See details and how to joinNCT04913805
Phase 3Taking people
Home-based Cardiac Rehabilitation in Heart Failure
Where
Dallas
Age
18 years and over
People
332
Run by
University of Texas Southwestern Medical Center
See details and how to joinNCT06349941
No phaseTaking people
AI-Enabled Direct-from-ECG Ejection Fraction (EF) Severity Assessment Using COR ECG Wearable Monitor
Where
Austin, Detroit, Greensboro, Hackensack, New York, Orange, Pasadena, Weslaco
Age
18 years and over
People
2,000
Run by
Peerbridge Health, Inc
See details and how to joinNCT06699056
No phaseTaking people
A Trial Comparing High-Flow Nasal Cannula Versus Noninvasive Ventilation on Reintubation and Post-Extubation Respiratory Failure in High-Risk Patients With Systolic Heart Failure
Where
New Haven
Age
18 years and over
People
50
Run by
Yale University
See details and how to joinNCT06671015
No phaseTaking people
IEEM-Heat and Heart Failure
Where
Dallas
Age
45 years and over
People
88
Run by
University of Texas Southwestern Medical Center
See details and how to joinNCT06961929
No phaseTaking people
BOOST: Blended Onsite and Offsite Structured Exercise Training and Coaching
Where
Winston-Salem
Age
55 years and over
People
14
Run by
Wake Forest University Health Sciences
See details and how to joinNCT07413198
Phase 1Taking people
Mechanisms of Diuretic Resistance in Heart Failure, Aim 1
Where
New Haven
Age
18 years and over
People
75
Run by
Yale University
See details and how to joinNCT05323487
No phaseTaking people
Wearable Technology to Evaluate Hyperglycemia and HRV in DMD
Where
Nashville
Age
10 years and over
People
80
Run by
Vanderbilt University Medical Center
See details and how to joinNCT06124196
Phase 1Taking people
Mechanisms of Diuretic Resistance in Heart Failure, Aim 3
Where
New Haven
Age
18 years and over
People
50
Run by
Yale University
See details and how to joinNCT06209359
No phaseTaking people
Effects of Dexrazoxane Hydrochloride on Biomarkers Associated With Cardiomyopathy and Heart Failure After Cancer Treatment
Where
Akron, Albuquerque, Asheville, Atlanta, Baltimore, Birmingham, Boston, Buffalo, Burlington, Charleston, Chicago, Cincinnati, Columbia, Dallas, Detroit, Duarte, Flint, Fort Myers, Fort Worth, Gainesville, Greenville, Hackensack, Hollywood, Honolulu, Houston, Jackson, Jacksonville, Las Vegas, Lebanon, Little Rock, Madera, Milwaukee, New Haven, New Hyde Park, New Orleans, Oakland, Oak Lawn, Oklahoma City, Orlando, Palo Alto, Peoria, Philadelphia, Phoenix, Portland, Providence, Richmond, Rochester, San Antonio, San Diego, Scarborough, Seattle, Spokane, St Louis, Stony Brook, St. Petersburg, Syracuse, Tampa, Tucson, West Palm Beach, Winston-Salem
People
420 worldwide
Run by
Children's Oncology Group
See details and how to joinNCT01790152
Phase 3Taking people
Study to Evaluate Efficacy and Safety of Inclisiran in Children With Heterozygous Familial Hypercholesterolemia
Where
Boca Raton, Morgantown, New York, Richmond, Salt Lake City, San Francisco, Washington D.C.
Age
6 years to 11 years
People
60 worldwide
Run by
Novartis Pharmaceuticals
See details and how to joinNCT06597019
No phaseTaking people
Exploring Water-free Sodium Storage
Where
New Haven
Age
18 years and over
People
10
Run by
Yale University
See details and how to joinNCT06872645
No phaseTaking people
CV Imaging of Metabolic Interventions
Where
Cleveland
Age
18 years and over
People
150
Run by
The Cleveland Clinic
See details and how to joinNCT05650307
No phaseTaking people
Development of CIRC Technologies
Where
Cleveland
Age
18 years and over
People
1,000
Run by
The Cleveland Clinic
See details and how to joinNCT05654272
No phaseTaking people
Early Assessment and Initiation of GuideLine-Directed Evidence-Based Management-HF
Where
Cleveland
Age
40 years and over
People
1,000
Run by
The Cleveland Clinic
See details and how to joinNCT06849752
No phaseTaking people
Targeting Breathing Limitations to Improve Functional Outcomes in HFpEF
Where
Dallas
Age
55 years to 90 years
People
78
Run by
University of Texas Southwestern Medical Center
See details and how to joinNCT05723679
No phaseTaking people
Routine Validation and Reproducibility Testing of Laboratory Assays and Research Techniques Used for Endocrine, Cardiometabolic, and Musculoskeletal Disorder Research (VALD)
Where
Columbia
Age
18 years to 100 years
People
100
Run by
Bettina Mittendorfer
See details and how to joinNCT07083557
Phase 2Taking people
The Inorganic Nitrate and eXercise Performance in Heart Failure (iNIX-HF)
Where
St Louis
Age
19 years to 79 years
People
75
Run by
Washington University School of Medicine
See details and how to joinNCT05562167
Phase 2Taking people
CAMEO-FONTAN -Dapagliflozin in the Failing Fontan Circulation
Where
Rochester
Age
18 years and over
People
27
Run by
Mayo Clinic
See details and how to joinNCT06762964
No phaseTaking people
Improving Medication Adherence Using Family-focused and Literacy-sensitive Strategies
Where
Lexington
Age
18 years and over
People
328
Run by
Jia-Rong Wu
See details and how to joinNCT05548413
No phaseTaking people
Ultra-High Frequency - Electrocardiogram (UHF-ECG) for the Diagnosis of Ventricular Electrical Dyssynchrony (VED)
Where
Avondale, Charlottesville, Chicago, Columbus, Houston, Mesa, Rochester
Age
18 years and over
People
360 worldwide
Run by
VDI Technologies
See details and how to joinNCT06641362
No phaseTaking people
Splanchnic X: Splanchnic Nerve Block in Heart Failure With Reduced Ejection Fraction
Where
Durham
Age
18 years and over
People
54
Run by
Duke University
See details and how to joinNCT06733012
Phase 2Taking people
Repurposing Valsartan May Protect Against Pulmonary Hypertension
Where
Seattle
Age
18 years to 80 years
People
60
Run by
University of Washington
See details and how to joinNCT06053580