Haemophilia trials in Canada

In Canada 19 Also abroad 131

19 trials · From ClinicalTrials.gov, checked 13 November 2026. Ask the study team whether a trial fits you.

Phase 4Taking people
Efanesoctocog Alfa Prophylaxis in Patients With Hemophilia A With Synovial Hypertrophy
Where
Calgary, Hamilton, St. John's
Age
12 years and over
People
35 worldwide
Run by
Sanofi
See details and how to joinNCT06941870
Phase 1/2Taking people
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of NXT007 in Persons With Severe or Moderate Hemophilia A
Where
Hamilton, Vancouver
Age
2 years to 59 years
People
60 worldwide
Run by
Hoffmann-La Roche
See details and how to joinNCT05987449 · EU 2023-503906-35-00
Phase 3Taking people
A Clinical Study to Evaluate the Effects of NXT007 Compared to Emicizumab Prophylaxis in People With Hemophilia A
Where
London
Age
12 years and over
People
360 worldwide
Run by
Hoffmann-La Roche
See details and how to joinNCT07416604 · EU 2025-522435-33-00
Phase 3Taking people
A Research Study Investigating Denecimig (Mim8) in Adults With Acquired Haemophilia A
Where
Hamilton, Toronto, Vancouver
Age
18 years and over
People
84 worldwide
Run by
Novo Nordisk A/S
See details and how to joinNCT07830732 · EU 2026-525529-19-00
Phase 3Taking people
A Study to Investigate the Efficacy and Safety of Fitusiran Prophylaxis in Male Participants Aged 1 to Less Than 12 Years With Hemophilia A or B
Where
Hamilton, Montreal, Toronto
Age
1 year to 11 years
People
85 worldwide
Run by
Sanofi
See details and how to joinNCT07285460 · EU 2025-521858-42-00
Phase 3Taking people
Open-Label Extension Study of Marstacimab in Hemophilia Participants With or Without Inhibitors
Where
Edmonton, Hamilton
Age
1 year to 74 years
People
245 worldwide
Run by
Pfizer
See details and how to joinNCT05145127 · EU 2022-500470-33-00
No phaseTaking people
An Observational Study to Learn More About How Well Damoctocog Alfa Pegol Works in Previously Treated Children With Hemophilia A
Where
Many Locations
Age
7 years to 12 years
People
40 worldwide
Run by
Bayer
See details and how to joinNCT07088458
Phase 1/2Taking people
A Study to Investigate the Safety and Effectiveness of a Coagulation Factor IX Gene Insertion Therapy (REGV131-LNP1265) in Pediatric, Adolescent and Adult Participants With Hemophilia B
Where
Edmonton, Hamilton, Montreal
Age
2 years and over
People
130 worldwide
Run by
Regeneron Pharmaceuticals
See details and how to joinNCT06379789 · EU 2023-507260-40-00
Phase 3Taking people
A Clinical Trial of Study Medicine (Marstacimab) in Pediatric Patients With Hemophilia A or Hemophilia B
Where
Edmonton, Hamilton
Age
1 year to 17 years
People
100 worldwide
Run by
Pfizer
See details and how to joinNCT05611801 · EU 2022-500495-65-00
No phaseEnrolling by invitation
3D Ultrasound in Hemophilic Ankles
Where
Toronto
Age
5 years to 18 years
People
11
Run by
The Hospital for Sick Children
See details and how to joinNCT07452575
Phase 3Taking people
Safety and Effectiveness of Giroctocogene Fitelparvovec or Fidanacogene Elaparvovec in Patients With Hemophilia A or B Respectively
Where
Toronto
Age
18 years and over
People
173 worldwide
Run by
Pfizer
See details and how to joinNCT05568719
Phase 3Taking people
Efficacy and Safety of CSL222 (Etranacogene Dezaparvovec) Gene Therapy in Adults With Hemophilia B With Pretreatment Adeno-associated Virus Serotype 5 (AAV5) Neutralizing Antibodies (Nabs)
Where
Hamilton
Age
18 years and over
People
35 worldwide
Run by
CSL Behring
See details and how to joinNCT06003387 · EU 2023-509590-23-00
No phaseTaking people
Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)
Where
Montreal, Toronto
Age
0 years to 20 years
People
5,000 worldwide
Run by
Duke University
See details and how to joinNCT04278404
Phase 1Taking people
A Study of Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of SR604 in Two Participants Groups (Part A: Healthy Participants, and Part B: Participants With Hemophilia A or Hemophilia B or Factor VII Deficiency)
Where
Hamilton
Age
18 years to 60 years
People
31 worldwide
Run by
Equilibra Bioscience LLC
See details and how to joinNCT06349473
No phaseEnrolling by invitation
A Study Following Males With Haemophilia B on Prophylaxis With Refixia/REBINYN
Where
Calgary, Edmonton, Hamilton, St. John's, Toronto, Winnipeg
People
60 worldwide
Run by
Novo Nordisk A/S
See details and how to joinNCT03745924
No phaseTaking people
Efficacy, Safety & Utilisation of Nuwiq, Octanate and Wilate in Previously Untreated & Minimally Treated Haemophilia A Patients
Where
Edmonton, Hamilton
People
200 worldwide
Run by
Octapharma
See details and how to joinNCT03695978
No phaseTaking people
The European Paediatric Network for Haemophilia Management ( PedNet Registry)
Where
Montreal, Toronto
People
4,000 worldwide
Run by
PedNet Haemophilia Research Foundation
See details and how to joinNCT02979119
No phaseTaking people
Patient Reported Outcomes Burdens and Experiences - Phase 3
Where
Hamilton
People
1,000
Run by
McMaster University
See details and how to joinNCT03549858
No phaseTaking people
World Bleeding Disorders Registry
Where
Montreal
People
20,000
Run by
World Federation of Hemophilia
See details and how to joinNCT03327779