HIV trials in South Africa

In South Africa 56 Also abroad 790

56 trials · From ClinicalTrials.gov, checked 10 Nov 2026. Ask the study team whether a trial fits you.

Phase 2RecruitingTrial-stage medicine
Immunogenicity and Safety of Hecolin® in HIV Positive/Negative Adults and in Children
Where
Ga-Rankuwa, Johannesburg, Paarl
Age
2 years to 45 years
People
1,040
Run by
International Vaccine Institute
See details and how to joinNCT06306196Registry updated 2025-04-29
Phase 2RecruitingTrial-stage medicine
Rezafungin for Treatment of Pneumocystis Pneumonia in HIV Adults
Where
Cape Town, Johannesburg, Pretoria, Umhlanga
Age
18 years and over
People
50
Run by
Mundipharma Research Limited
See details and how to joinNCT05835479Registry updated 2025-04-03
Phase 3RecruitingTrial-stage medicine
Efficacy, Safety and Immunogenicity Evaluation of MTBVAC in Newborns in Sub-Saharan Africa
Where
Worcester
Age
5 Minutes to 7 days
People
7,120
Run by
Biofabri, S.L
See details and how to joinNCT04975178Registry updated 2025-02-10
No phaseRecruitingResearch participation
PrEPared to Choose (PtC) is an Implementation Study of the Delivery of Cabotegravir Long-acting, an Injectable Pre-exposure Prophylaxis (PrEP) Option for HIV Prevention. Injectable PrEP Will be Offered Alongside Oral and Vaginal Ring PrEP From Within a Real-world Context in Cape Town, South Africa.
Where
Cape Town
Age
15 years and over
People
1,800
Run by
Desmond Tutu HIV Foundation
See details and how to joinNCT06807736Registry updated 2025-02-04
No phaseRecruitingResearch participation
Improving HIV Testing, Linkage, and Retention in Care for Men Through U=U Messaging
Where
Cape Town, East London
Age
15 years and over
People
3,642
Run by
Desmond Tutu HIV Foundation
See details and how to joinNCT05602376Registry updated 2024-11-01
No phaseRecruitingResearch participation
B. Infantis Supplementation to Improve Immunity in Infants Exposed to HIV
Where
Cape Town
Age
0 days to 50 years
People
200
Run by
University of Cape Town
See details and how to joinNCT05923333Registry updated 2024-08-22

All HIV trials and the map

This page is not medical advice. Talk to your doctor before contacting a trial.

Report an error

HIV trials in South Africa

Immunogenicity and Safety of Hecolin® in HIV Positive/Negative Adults and in Children

Rezafungin for Treatment of Pneumocystis Pneumonia in HIV Adults

Efficacy, Safety and Immunogenicity Evaluation of MTBVAC in Newborns in Sub-Saharan Africa

PrEPared to Choose (PtC) is an Implementation Study of the Delivery of Cabotegravir Long-acting, an Injectable Pre-exposure Prophylaxis (PrEP) Option for HIV Prevention. Injectable PrEP Will be Offered Alongside Oral and Vaginal Ring PrEP From Within a Real-world Context in Cape Town, South Africa.

Improving HIV Testing, Linkage, and Retention in Care for Men Through U=U Messaging

B. Infantis Supplementation to Improve Immunity in Infants Exposed to HIV