Huntington's disease trials in United Kingdom

In United Kingdom 9 Also abroad 51

9 trials · From ClinicalTrials.gov, checked 11 November 2026. Ask the study team whether a trial fits you.

Phase 2/3Taking people
Study to Evaluate the Pharmacodynamics, Safety and Efficacy of SKY-0515 in Participants With Huntington's Disease
Where
London, Motherwell
Age
25 years and over
People
400 worldwide
Run by
Skyhawk Therapeutics, Inc.
See details and how to joinNCT07378644 · EU 2025-522263-14-00
Phase 3Taking people
Pridopidine Phase 3 Study in Huntington's Disease
Where
Aberdeen, Birmingham, Cardiff, Liverpool, Newcastle upon Tyne
Age
23 years to 65 years
People
400 worldwide
Run by
Prilenia
See details and how to joinNCT07609108 · EU 2026-526093-16-00
Phase 1Taking people
A First-in-human Study of the Effects of SRP-1005 in Participants With Huntington's Disease
Where
Cardiff
Age
21 years to 70 years
People
32 worldwide
Run by
Sarepta Therapeutics, Inc.
See details and how to joinNCT07536061
Phase 1Taking people
A Study to Evaluate ALN-HTT02 in Adult Patients With Huntington's Disease
Where
Birmingham, Cambridge, Cardiff, Glasgow, Greater Manchester, London, Oxford, Plymouth
Age
25 years to 70 years
People
66 worldwide
Run by
Alnylam Pharmaceuticals
See details and how to joinNCT06585449
Phase 3Taking people
A Study to Investigate the Efficacy, Safety and Tolerability of Votoplam in Participants With Huntington's Disease
Where
Aberdeen, Cambridge, Cardiff, Exeter, Glasgow, Leeds, London, Oxford, Southampton
Age
21 years to 70 years
People
770 worldwide
Run by
Novartis Pharmaceuticals
See details and how to joinNCT07326709 · EU 2025-522227-99-00
Phase 1/2Taking people
A Safety and Pharmacokinetics Trial of VO659 in SCA1, SCA3 and HD
Where
London, Oxford
Age
25 years to 60 years
People
68 worldwide
Run by
Vico Therapeutics B. V.
See details and how to joinNCT05822908 · EU 2024-514328-18-00
No phaseTaking people
HDClarity: a Multi-site Cerebrospinal Fluid Collection Initiative to Facilitate Therapeutic Development for Huntington's Disease
Where
Birmingham, Bristol, Cambridge, Cardiff, Exeter, Glasgow, Kirkcaldy, Leeds, Liverpool, London, Oxford, Plymouth
Age
11 years to 75 years
People
2,500 worldwide
Run by
University College, London
See details and how to joinNCT02855476
No phaseTaking people
IMarkHD: in Vivo Longitudinal Imaging of HD Pathology
Where
London
Age
21 years to 75 years
People
113
Run by
King's College London
See details and how to joinNCT03434548
No phaseTaking people
Enroll -HD: A Prospective Registry Study in a Global Huntington's Disease Cohort
Where
Aberdeen, Birmingham, Bristol, Cambridge, Cardiff, Dundee, Edinburgh, Exeter, Glasgow, Kilmarnock, Kirkcaldy, Larbert, Leeds, Liverpool, London, Manchester, Narborough, Newcastle upon Tyne, Northampton, Oxford, Plymouth, Poole, Reading, Sheffield, Southampton, Stoke-on-Trent, Swindon, Wrexham
Age
18 years and over
People
35,000 worldwide
Run by
CHDI Foundation, Inc.
See details and how to joinNCT01574053