Hypertrophic cardiomyopathy trials in Italy

In Italy 8 Also abroad 88

8 trials · From ClinicalTrials.gov and EU CTIS (euclinicaltrials.eu), checked 11 November 2026. Ask the study team whether a trial fits you.

Phase 2Taking people
A randomized, double-blinded, placebo-controlled trial to evaluate the efficacy and safety of ninerafaxstat in patients with symptomatic non-obstructive hypertrophic cardiomyopathy
Where
Bologna, Florence, Milan, Naples, Pisa, San Donato Milanese
Age
18 years and over
People
130 worldwide
Run by
Imbria Pharmaceuticals Inc.
See details and how to join2024-515125-28-00 · EU 2024-515125-28-00
Phase 2Taking people
A Trial to Evaluate the Efficacy and Safety of Ninerafaxstat in Patients With Symptomatic Non-obstructive Hypertrophic Cardiomyopathy
Where
Bologna, Florence, Massa, Milan, Naples
Age
18 years and over
People
165 worldwide
Run by
Imbria Pharmaceuticals, Inc.
See details and how to joinNCT07023614
Phase 2/3Enrolling by invitation
Open-label Extension Study to Evaluate the Long-term Safety and Tolerability of Aficamten in Adults With HCM
Where
Florence, Milan, Naples, Pisa, Rome, San Donato Milanese, Trieste
Age
18 years to 85 years
People
900 worldwide
Run by
Cytokinetics
See details and how to joinNCT04848506 · EU 2023-508963-58-00
Phase 2Taking people
A Gene Therapy Study of RP-A501 in Male Patients With Danon Disease
Where
Florence
Age
8 years and over
People
18 worldwide
Run by
Rocket Pharmaceuticals Inc.
See details and how to joinNCT06092034
No phaseTaking people
Myocardial Perfusion CMR for Differentiating and Characterizing Hypertrophic Cardiomyopathy Phenotypes
Where
Bologna
Age
18 years and over
People
250
Run by
IRCCS Azienda Ospedaliero-Universitaria di Bologna
See details and how to joinNCT07382128
No phaseTaking people
Characterization of Patients With Cardiomyopathy to Identify Critical Patients Candidates for Cardiac Transplantation
Where
Bologna, Florence, Roma
Age
12 years and over
People
700
Run by
IRCCS Azienda Ospedaliero-Universitaria di Bologna
See details and how to joinNCT06813443
No phaseTaking people
Multimodal and Multidisciplinary Approach to Optimize Diagnostic, Prognostic, and Therapeutic Management of Patients with Non-ischemic Cardiomyopathies and Arrhythmogenic-inflammatory Phenotypes: a Multicenter, Observational, Retrospective and Prospective Registry Study.
Where
Milan
Age
18 years and over
People
15,000
Run by
Scientific Institute San Raffaele
See details and how to joinNCT06607471
No phaseTaking people
Stress Echo 2030: the Novel ABCDE-(FGLPR) Protocol to Define the Future of Imaging
Where
Benevento
Age
18 years to 75 years
People
10,000
Run by
Fatebenefratelli Hospital
See details and how to joinNCT05081115