Hypothyroidism trials in United States

In United States 10 Also abroad 52

10 trials · From ClinicalTrials.gov, checked 13 November 2026. Ask the study team whether a trial fits you.

No phaseTaking people
Natural History of Thyroid Function Disorders
Where
Bethesda
Age
6 months to 98 years
People
2,500
Run by
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
See details and how to joinNCT00001159
No phaseTaking people
Clinical and Basic Investigations Into Known and Suspected Congenital Disorders of Glycosylation
Where
Bethesda
Age
1 month to 80 years
People
200
Run by
National Human Genome Research Institute (NHGRI)
See details and how to joinNCT02089789
No phaseTaking people
Optimizing Care for Older Adults Through Thyroid Hormone Deprescribing
Where
Ann Arbor, Detroit, San Francisco
Age
65 years and over
People
900
Run by
University of Michigan
See details and how to joinNCT06629272
Phase 4Not yet taking people in United States
Discontinuation of Low-Dose Levothyroxine in Older Adults With Subclinical Hypothyroidism
Where
Gainesville, Little Rock, Rochester
Age
65 years and over
People
138
Run by
Spyridoula Maraka
See details and how to joinNCT07787585
Phase 2Not yet taking people in United States
T4/T3 Therapy in Hypothyroidism
Where
Philadelphia
Age
18 years to 70 years
People
60
Run by
University of Pennsylvania
See details and how to joinNCT07424183
Phase 3Taking people
An Open-Label, Single-Arm Study to Investigate the Efficacy and Safety of North Star Desiccated Porcine Thyroid Extract Tablets.
Where
Aurora, Boise, Boston, Charleston, Charlottesville, Chattanooga, Dallas, Georgetown, Lakeland, Largo, Las Vegas, Methuen, Miami, Miami Lakes, Modesto, North Charleston, Palm Springs, Raleigh, Redding, San Diego, Sugar Land, Sunrise, Walnut Creek, Winston-Salem
Age
18 years to 75 years
People
466
Run by
Neuvosyn Laboratories, LLC
See details and how to joinNCT07747103
No phaseTaking people
Natural History of Sphingosine Phosphate Lyase Insufficiency Syndrome (SPLIS)
Where
San Francisco
People
28
Run by
University of California, San Francisco
See details and how to joinNCT06669949
Phase 2/3Taking people
Novel Approaches to the Treatment of Hypothyroidism
Where
Farmington
Age
18 years and over
People
90
Run by
UConn Health
See details and how to joinNCT06731764
Phase 4Taking people
Dosing of LT4 in Older Individuals
Where
Philadelphia
Age
65 years and over
People
228
Run by
University of Pennsylvania
See details and how to joinNCT06073665
No phaseTaking people
A Randomized Controlled Trial of Thyroid Hormone Supplementation in Hemodialysis Patients
Where
Orange
Age
18 years to 75 years
People
336
Run by
University of California, Irvine
See details and how to joinNCT03977207