Insomnia trials in United States

In United States 126 Also abroad 347

126 trials · From ClinicalTrials.gov, checked 13 November 2026. Ask the study team whether a trial fits you.

No phaseTaking people
Parent-Mediated Telehealth Intervention for Insomnia in Young Autistic Children
Where
Cleveland, Columbus
Age
3 years to 7 years
People
130
Run by
The Cleveland Clinic
See details and how to joinNCT07435740
Early phase 1Taking people
CBTi for the Treatment of Insomnia in Type 1 Diabetes
Where
Chicago
Age
18 years to 65 years
People
15
Run by
University of Illinois Chicago
See details and how to joinNCT07091318
Phase 1Taking people
Early Cognitive Behavioral Therapy for Insomnia (CBT-I) in People Planning to Under Hematopoietic Stem Cell Transplant (HSCT)
Where
Kansas City
Age
18 years and over
People
30
Run by
University of Kansas Medical Center
See details and how to joinNCT07774039
No phaseTaking people
Insomnia and Insulin Resistance
Where
Columbia
Age
18 years to 50 years
People
20
Run by
University of Missouri-Columbia
See details and how to joinNCT07333586
No phaseNot yet taking people in United States
Does the Timing of Insomnia Therapy (CBT-i) Impact the Usage and Compliance of Upper Airway Stimulation (UAS) Treatment of Obstructive Sleep Apnea (OSA)
Where
Pittsburgh
Age
18 years and over
People
100
Run by
Thomas Kaffenberger
See details and how to joinNCT07838870
Phase 3Taking people
A Study of Suvorexant (MK-4305) for the Treatment of Insomnia Disorder in Participants With Opioid Use Disorder (MK-4305-098)
Where
Baltimore, Bradenton, Charleston, DeSoto, Garden Grove, Houston, Marlton, New Haven, Oklahoma City, Philadelphia, Providence, Richmond, Savannah
Age
18 years to 70 years
People
300
Run by
Merck Sharp & Dohme LLC
See details and how to joinNCT06655883
Phase 4Taking people
A SMART Approach to Evaluating the Benefits of Common Prescription and OTC Medications for Insomnia
Where
Philadelphia
Age
18 years to 80 years
People
1,200
Run by
University of Pennsylvania
See details and how to joinNCT07542756
No phaseTaking people
Sleep as a Mechanism of Change in Alcohol Use
Where
Columbia
Age
18 years to 49 years
People
256
Run by
University of Missouri-Columbia
See details and how to joinNCT06286774
No phaseTaking people
Digital Sleep Optimization for Brain Health Outcomes in Older Surgical Patients
Where
Boston
Age
65 years and over
People
50
Run by
Massachusetts General Hospital
See details and how to joinNCT06375265
No phaseTaking people
Digital Cognitive Behavioral Treatment of Insomnia in Youth: An RCT Examining Feasibility, Acceptability, and Efficacy of NiteCAPP Jr
Where
Tampa
Age
6 years to 12 years
People
40
Run by
University of South Florida
See details and how to joinNCT07091149
No phaseTaking people
Enhancing Diabetes Care by Treating Insomnia
Where
Zachary
Age
40 years and over
People
30
Run by
Tulane University
See details and how to joinNCT07062406
Phase 2Not yet taking people in United States
THC Versus THC/CBD Versus Placebo to Improve Sleep Quality for Patients With Solid Organ Cancer and Insomnia
Where
Rochester
Age
25 years and over
People
69
Run by
Mayo Clinic
See details and how to joinNCT07565974
No phaseTaking people
Piloting an Insomnia Treatment in Patients With Ulcerative Colitis
Where
Lebanon
Age
18 years and over
People
20
Run by
Dartmouth-Hitchcock Medical Center
See details and how to joinNCT07428629
No phaseEnrolling by invitation
NeuroFinance Human Stress Trial During Financial and Informational Volatility
Where
New York
Age
18 years and over
People
2,500
Run by
Truway Health, Inc.
See details and how to joinNCT07622589
No phaseTaking people
Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)
Where
Albuquerque, Aurora, Austin, Baltimore, Boston, Chapel Hill, Charleston, Chicago, Cincinnati, Columbia, Dallas, Durham, Hershey, Honolulu, Houston, Indianapolis, Iowa City, Jackson, Jacksonville, Kansas City, Lebanon, Lexington, Little Rock, Los Angeles, Louisville, Madison, Milwaukee, Minneapolis, Morgantown, Nashville, New Orleans, Oklahoma City, Omaha, Palo Alto, Phoenix, Portland, Providence, Salt Lake City, Seattle, Sioux Falls, Wilmington
Age
0 years to 20 years
People
5,000 worldwide
Run by
Duke University
See details and how to joinNCT04278404
No phaseTaking people
Transcutaneous Auricular Vagus Nerve Stimulation for Insomnia in Survivors of Childhood Acute Lymphoblastic Leukemia
Where
Memphis
Age
20 years to 50 years
People
40
Run by
St. Jude Children's Research Hospital
See details and how to joinNCT07191119
No phaseTaking people
OBSERVE: Biomarkers in Individuals at Risk for Prion Disease
Where
Charlestown
Age
18 years to 85 years
People
150
Run by
Massachusetts General Hospital
See details and how to joinNCT05124392
No phaseTaking people
Multi-center Trial to Improve Nocturia and Sleep in Older Adults
Where
Atlanta, Los Angeles
Age
60 years and over
People
192
Run by
Atlanta VA Medical Center
See details and how to joinNCT06110091
No phaseEnrolling by invitation
Effects of Accelerated rTMS on Sleep Architecture in Chronic Insomnia Disorder
Where
San Francisco
Age
18 years to 85 years
People
70
Run by
San Francisco Neurology and Sleep Center
See details and how to joinNCT07595185
No phaseTaking people
Does Style Matter: Comparison of Moderate- to Low-intensity Styles of Yoga
Where
Orlando
Age
18 years to 40 years
People
42
Run by
Caitlin Cheruka
See details and how to joinNCT07638267
No phaseEnrolling by invitation
SHADES Mechanistic Trial
Where
Indianapolis
Age
40 years and over
People
200
Run by
Indiana University
See details and how to joinNCT06041581
No phaseEnrolling by invitation
Sleep Treatment Education Program for Cancer Survivors: STEP-Together
Where
Boston
Age
18 years to 89 years
People
100
Run by
Dana-Farber Cancer Institute
See details and how to joinNCT06736548
No phaseNot yet taking people in United States
Sleep Interventions and Neurocognitive Outcomes
Where
New York
Age
60 years to 85 years
People
50
Run by
New York State Psychiatric Institute
See details and how to joinNCT05987007
No phaseTaking people
Affect of Melatonin on Sleep and Cognition in Cirrhosis
Where
New York
Age
18 years and over
People
18
Run by
Weill Medical College of Cornell University
See details and how to joinNCT07046429
No phaseTaking people
Treatments for Insomnia in Veterans With PTSD
Where
Miami, Sepulveda
Age
18 years and over
People
400
Run by
VA Office of Research and Development
See details and how to joinNCT05194930