Insomnia trials in United States

In United States 126 Also abroad 347

126 trials · From ClinicalTrials.gov, checked 13 November 2026. Ask the study team whether a trial fits you.

Phase 3Taking people
Studying Solriamfetol Modulation of TAAR-1, Dopamine, and Norepinephrine in Shift Work Disorder (SUSTAIN)
Where
Anaheim, Atlanta, Auburn, Boston, Brandon, Cerritos, Chandler, Charleston, Chesterfield, Chicago, Chula Vista, Cincinnati, Colorado Springs, Columbia, Cullman, Denver, Fayetteville, Henderson, Hialeah, Houston, Huntersville, Huntington Beach, Kenner, Lansing, Little Rock, Long Beach, Miami, Miami Lakes, Middletown, Novi, San Antonio, Santa Ana, Southfield, Spokane, St Louis, Stockbridge, Sugar Land, Towson, Tucson, Wyomissing
Age
18 years to 65 years
People
520 worldwide
Run by
Axsome Therapeutics, Inc.
See details and how to joinNCT06568367
No phaseNot yet taking people in United States
Evaluating the Impact of Digital Behavioral Interventions to Address Insomnia and Depression in Breast Cancer Survivors Using an Adaptive Design
Where
Charlottesville
Age
18 years and over
People
747
Run by
University of Virginia
See details and how to joinNCT07721064
No phaseTaking people
Cereset Research Exploratory Study
Where
Winston-Salem
Age
11 years and over
People
200
Run by
Wake Forest University Health Sciences
See details and how to joinNCT03777267
No phaseTaking people
Comparing Acoustic Resonance Therapy (ART) vs. Cognitive Behavioral Therapy for Insomnia (CBT-I)
Where
Rochester
Age
22 years and over
People
60
Run by
Mayo Clinic
See details and how to joinNCT07486882
Phase 2Not yet taking people in United States
Daridorexant for People With Insomnia and Alcohol Use Disorder Study
Where
Spokane
Age
18 years and over
People
205
Run by
Sterling McPherson
See details and how to joinNCT07701928
Phase 2Taking people
Sleep Trial to Prevent Alzheimer's Disease
Where
St Louis
Age
65 years and over
People
120
Run by
University of Minnesota
See details and how to joinNCT04629547
No phaseTaking people
CBT-I vs. MBTI for Traumatic Brain Injury (TBI)-Related Insomnia and Post-Traumatic Stress Symptoms
Where
Bethesda, Eglin Air Force Base, Fort Bragg, Fort Lewis
Age
18 years and over
People
360
Run by
Johns Hopkins University
See details and how to joinNCT05663034
Phase 2Taking people
Effects of Lemborexant on Insomnia and Its Relationship to Mood and Behavior on Opioid Use Disorder Subjects
Where
Richmond
Age
18 years and over
People
100
Run by
Virginia Commonwealth University
See details and how to joinNCT06981195
No phaseTaking people
Healthy Behaviors for Insomnia Prevention in People With HIV and Ongoing Pain
Where
St Louis
Age
25 years to 65 years
People
200
Run by
Washington University School of Medicine
See details and how to joinNCT07270406
Phase 4Not yet taking people in United States
Suvorexant 3 - PE-PC
Where
San Francisco
Age
18 years to 75 years
People
142
Run by
Northern California Institute of Research and Education
See details and how to joinNCT07686731
Phase 1/2Taking people
Mindfulness Meditation for Insomnia
Where
Boston
Age
18 years and over
People
30
Run by
Brigham and Women's Hospital
See details and how to joinNCT06972303
No phaseTaking people
Web-based Cognitive Behavioral Treatment for Insomnia in Dementia Caregivers
Where
Columbia
Age
18 years and over
People
60
Run by
University of South Florida
See details and how to joinNCT04632628
No phaseTaking people
Training in Evidence-based Treatments in Psycho-Oncology
Where
Boston
Age
18 years and over
People
115
Run by
Massachusetts General Hospital
See details and how to joinNCT05674357
Phase 4Taking people
Comparing Digital Therapy, Trazodone, and Daridorexant for Menopause-Related Insomnia Symptoms
Where
Boston, Novi, Pittsburgh, Salt Lake City, Winston-Salem
Age
40 years to 62 years
People
1,000
Run by
Brigham and Women's Hospital
See details and how to joinNCT07136415
Phase 2Taking people
Neural Mechanisms Connecting Deficient Sleep and Smoking Relapse
Where
New Haven
Age
18 years to 65 years
People
114
Run by
Yale University
See details and how to joinNCT06609369
Phase 3Taking people
Evaluating the Effects of Tasimelteon vs. Placebo in Treating Pediatric Insomnia
Where
Cleveland, Columbia, Dothan, Great Falls, Houston, Irvine, Las Vegas, Lincoln, Miami, Miami Lakes, Myrtle Beach, Naperville, Nashville, Phoenix, Plano, San Antonio, Snellville, Stockbridge, Winter Park, Worcester
Age
2 years to 17 years
People
420 worldwide
Run by
Vanda Pharmaceuticals
See details and how to joinNCT06953869 · EU 2024-516411-24-00
No phaseTaking people
Adapted CBT-I for Adolescents With Insomnia : The DREAM-IT Study
Where
Indianapolis
Age
13 years to 18 years
People
28
Run by
Indiana University
See details and how to joinNCT06541886
No phaseTaking people
Cereset Research for Caregivers
Where
Winston-Salem
Age
18 years and over
People
20
Run by
Wake Forest University Health Sciences
See details and how to joinNCT05209438
Phase 4Taking people
Neurocognitive Function Changes With Extended-Release Tacrolimus Among Older Kidney Transplant Recipients
Where
Boston
Age
65 years and over
People
92
Run by
Massachusetts General Hospital
See details and how to joinNCT06751992
No phaseTaking people
Targeting Insomnia to Improve Outcomes in Adults With Problematic Cannabis Use
Where
Ann Arbor
Age
21 years and over
People
200
Run by
University of Michigan
See details and how to joinNCT05814822
No phaseTaking people
ASV Therapy for Insomnia
Where
Detroit
Age
18 years and over
People
25
Run by
ResMed
See details and how to joinNCT07011966
No phaseNot yet taking people in United States
The Impact of Brief Behavioral Treatment for Insomnia Versus Brief Mindfulness Treatment on Cognition and Sleep Health in Adults (Age 50+) With HIV
Where
Birmingham, Tuscaloosa
Age
50 years to 99 years
People
214
Run by
University of Alabama, Tuscaloosa
See details and how to joinNCT07272863
No phaseTaking people
A Hybrid Effectiveness Implementation Trial Evaluating Behavioral Treatments for Insomnia for Socioeconomically Disadvantaged Adults in Primary Care
Where
Boston
Age
18 years and over
People
350
Run by
Brigham and Women's Hospital
See details and how to joinNCT05759065
No phaseTaking people
Implementing Cognitive Behavioral Therapy for Insomnia (SWELL): Function QUERI 3.0
Where
Durham
Age
60 years and over
People
20
Run by
VA Office of Research and Development
See details and how to joinNCT07216261
No phaseTaking people
COMPARATIVE EFFECTIVENESS OF EXERCISE, COGNITIVE BEHAVIOURAL THERAPY, AND THEIR COMBINATION FOR PEOPLE WITH CHRONIC MUSCULOSKELETAL PAIN AND POOR SLEEP: SLEEPFIT TRIAL
Where
San Antonio
Age
18 years and over
People
384 worldwide
Run by
University of Sydney
See details and how to joinNCT07532070