Liver and biliary tract cancer trials in Netherlands

In Netherlands 38 Also abroad 1314

38 trials · From ClinicalTrials.gov and EU CTIS (euclinicaltrials.eu), checked 11 November 2026. Ask the study team whether a trial fits you.

Phase 1Taking people
A Study of LY4337713 in Participants With FAP-Positive Solid Tumors
Where
Amsterdam, Maastricht, Nijmegen, Utrecht
Age
18 years and over
People
340 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT07213791 · EU 2025-521887-37-00
Phase 3Taking people
The effect of [18F]F-FAPI PET-CT on management in patients with potentially resectable biliary tract cancers: prospective multicenter study and cost-effectivity analysis.
Where
Amsterdam, Rotterdam, Utrecht
Age
18 years and over
People
81
Run by
Erasmus Universitair Medisch Centrum Rotterdam (Erasmus MC)
See details and how to join2023-507938-24-00 · EU 2023-507938-24-00
Phase 1/2Taking people
A Study to Evaluate the Efficacy and Safety of Ifinatamab Deruxtecan (I-DXd) in Subjects With Recurrent or Metastatic Solid Tumors (IDeate-PanTumor02)
Where
Amsterdam, Groningen, Nijmegen, Rotterdam, Utrecht
Age
18 years and over
People
680 worldwide
Run by
Daiichi Sankyo
See details and how to joinNCT06330064 · EU 2023-509632-26-00
No phaseNot yet taking people in Netherlands
Overcoming Immunotherapy Resistance in Hepatocellular Carcinoma
Where
Nijmegen
Age
18 years and over
People
16
Run by
Radboud University Medical Center
See details and how to joinNCT07895342
Phase 2Taking people
Gemcitabine and Oxaliplatin Chemotherapy With or Without a Floxuridine and Dexamethasone Pump in People With Cholangiocarcinoma That Cannot Be Removed With Surgery
Where
Rotterdam
Age
18 years and over
People
164 worldwide
Run by
Memorial Sloan Kettering Cancer Center
See details and how to joinNCT04891289 · EU 2024-518065-10-00
Phase 3Taking people
Phase 3 Study of T-DXd and Rilvegostomig Versus SoC in Advanced HER2-expressing Biliary Tract Cancer
Where
Rotterdam
Age
18 years to 99 years
People
620 worldwide
Run by
AstraZeneca
See details and how to joinNCT06467357 · EU 2023-508057-19-00
Phase 3Taking people
Phase III Study of Rilvegostomig in Combination With Bevacizumab With or Without Tremelimumab as First-line Treatment of Hepatocellular Carcinoma
Where
Amsterdam, Groningen, Maastricht, Rotterdam, Utrecht
Age
18 years and over
People
1,220 worldwide
Run by
AstraZeneca
See details and how to joinNCT06921785 · EU 2024-518210-81-00
Phase 1/2Not yet taking people in Netherlands
Hepatic arterial infusion versus intravenous oxaliplatin in a safety, feasibility, and pharmacokinetic study of liver-dominant malignancies – ARTEMIS OXYS-I trial
Where
Rotterdam
Age
18 years and over
People
13
Run by
Erasmus Universitair Medisch Centrum Rotterdam (Erasmus MC)
See details and how to join2026-527509-39-01 · EU 2026-527509-39-01
Phase 3Taking people
A clinical trial of belzutifan and other treatments in people with solid tumors or von Hippel-Lindau (VHL)-related tumors (MK-6482-043)
Where
Amsterdam, Maastricht, Zwolle
Age
18 years and over
People
134 worldwide
Run by
Merck Sharp & Dohme LLC
See details and how to join2025-524160-38-00 · EU 2025-524160-38-00
Phase 3Taking people
A Study of Rilvegostomig or Durvalumab Plus Chemotherapy for First-Line Treatment of Biliary Tract Cancer (ARTEMIDE-Biliary02)
Where
Amsterdam, Groningen, Maastricht, Utrecht
Age
18 years and over
People
1,100 worldwide
Run by
AstraZeneca
See details and how to joinNCT07221253 · EU 2025-523085-24-00
Phase 2Taking people
Additional Chemotherapy Administered Directly Into the Liver Using a Chemo Pump in Patients With Bile Duct Cancer Inside the Liver Treatable by Surgery
Where
Amsterdam, Groningen, Maastricht, Rotterdam, Utrecht
Age
18 years and over
People
40
Run by
Erasmus Medical Center
See details and how to joinNCT06888063 · EU 2024-513726-33-00
No phaseTaking people
Preoperative Evaluation of Lymph Nodes of Cholangiocarcinoma (POELH-III)
Where
Amsterdam, Groningen, Leiden, Maastricht, Rotterdam, Utrecht
Age
18 years and over
People
250
Run by
Erasmus Medical Center
See details and how to joinNCT07161869
No phaseTaking people
Registry of Minimally Invasive Cancer Treatment Using Spectral Angio-CT Image Guidance
Where
Leiden
Age
18 years and over
People
2,000 worldwide
Run by
Mark C Burgmans, MD PhD
See details and how to joinNCT07636148
Phase 2/3Taking people
Neoadjuvant Gemcitabine and Cisplatin in Combination With Perioperative Pembrolizumab Versus Upfront Surgery for Patients With Primary Resectable and Borderline Resectable Perihilar and Distal Cholangiocarcinoma
Where
Amsterdam
Age
18 years and over
People
150
Run by
Amsterdam UMC, location VUmc
See details and how to joinNCT06923475
Phase 2Taking people
A Study to Assess the Efficacy and Safety of FORE8394 in Participants With Cancer Harboring BRAF Alterations
Where
Rotterdam
Age
8 years and over
People
254 worldwide
Run by
Fore Biotherapeutics
See details and how to joinNCT05503797 · EU 2024-513578-23-00
Phase 1Taking people
A Study of PF-08046054/SGN-PDL1V in Advanced Solid Tumors
Where
Amsterdam
Age
18 years and over
People
714 worldwide
Run by
Seagen, a wholly owned subsidiary of Pfizer
See details and how to joinNCT05208762 · EU 2023-506604-18-00
Phase 2Taking people
Randomized Study to Evaluate Melphalan/HDS Treatment Followed by Trifluridine–tipiracil plus Bevacizumab Versus Trifluridine–tipiracil plus Bevacizumab Alone in Metastatic Colorectal Cancer Patients
Where
Leiden
Age
18 years and over
People
35 worldwide
Run by
Delcath Systems Inc.
See details and how to join2024-520356-24-00 · EU 2024-520356-24-00
No phaseTaking people
DRAGON Registry - International Multicenter Registry and Medical Image Bank for Patients With Primarily Unresectable Liver Cancer or Liver Metastases That Underwent Combined Portal and Hepatic Vein Embolization (PVE/HVE) to Increase Future Liver Remnant Before Resection.
Where
Amsterdam, Groningen, Leiden, Maastricht, Rotterdam
Age
18 years and over
People
350 worldwide
Run by
Maastricht University Medical Center
See details and how to joinNCT07717437
Phase 1/2Taking people
A Study to Investigate ALE.P03 as Monotherapy in Adult Patients With Selected Advanced or Metastatic CLDN1+ Solid Tumors
Where
Amsterdam, Nijmegen, Rotterdam
Age
18 years and over
People
180 worldwide
Run by
Alentis Therapeutics AG
See details and how to joinNCT07169734 · EU 2025-521441-24-00
No phaseTaking people
Endobiliary Radiofrequency Ablation for Malignant Biliary Obstruction Due to Perihilar Cholangiocarcinoma
Where
Amsterdam
Age
18 years and over
People
122
Run by
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
See details and how to joinNCT05546372
Phase 2Taking people
Radioembolization With Intra-arterial Angiotensin II to Improve Tumor-absorbed Dose (RADIANT)
Where
Utrecht
Age
18 years and over
People
15
Run by
Niek Wijnen
See details and how to joinNCT07312292 · EU 2025-521870-33-00
No phaseTaking people
The MOMENTUM Study: The Multiple Outcome Evaluation of Radiation Therapy Using the MR-Linac Study
Where
Amsterdam, Deventer, Leeuwarden, Nijmegen, Utrecht
Age
18 years and over
People
8,000 worldwide
Run by
UMC Utrecht
See details and how to joinNCT04075305
Phase 4Taking people
HOPE Against Cancer Recurrence in HCC
Where
Groningen, Rotterdam
Age
18 years and over
People
220 worldwide
Run by
Philipp Dutkowski
See details and how to joinNCT06717919
Phase 2/3Taking people
Neoadjuvant gemcitabine and cisplatin in combination with perioperative pembrolizumab versus upfront surgery for patients with primary resectable and borderline resectable perihilar and distal cholangiocarcinoma (NEODISCO): A Multicentre Phase 2B/3 Randomised Controlled Trial
Where
Amsterdam, Groningen, Maastricht, Rotterdam, Utrecht
Age
18 years and over
People
5
Run by
Stichting Amsterdam UMC
See details and how to join2024-516898-72-00 · EU 2024-516898-72-00
Phase 1Taking people
Molecular imaging with FAPI for diagnosing the CSM4 colorectal cancer subtype
Where
Utrecht
Age
18 years and over
People
45
Run by
Universitair Medisch Centrum Utrecht
See details and how to join2023-509183-17-00 · EU 2023-509183-17-00