Lyme disease trials in United States

In United States 16 Also abroad 29

16 trials · From ClinicalTrials.gov, checked 13 November 2026. Ask the study team whether a trial fits you.

No phaseTaking people
Evaluation, Treatment, and Follow-up of Patients With Lyme Disease
Where
Bethesda
Age
2 years to 99 years
People
500
Run by
National Institute of Allergy and Infectious Diseases (NIAID)
See details and how to joinNCT00028080
No phaseTaking people
Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford
Where
Sioux Falls
People
20,000
Run by
Sanford Health
See details and how to joinNCT01793168
No phaseTaking people
Sana Device for Post-Treatment Lyme Disease Syndrome Chronic Pain
Where
New York
Age
18 years and over
People
20
Run by
Icahn School of Medicine at Mount Sinai
See details and how to joinNCT06655844
No phaseTaking people
A Comprehensive Clinical, Microbiological and Immunological Assessment of Patients With Suspected Post Treatment Lyme Disease Syndrome and Selected Control Populations
Where
Bethesda
Age
13 years to 99 years
People
800
Run by
National Institute of Allergy and Infectious Diseases (NIAID)
See details and how to joinNCT00001539
No phaseNot yet taking people in United States
The Precision Mito- Mito Map COMPASS Study
Where
Fort Myers
Age
18 years and over
People
400
Run by
AI Agent Vault, Inc. d/b/a Precision Mito
See details and how to joinNCT07856121
Phase 1/2Taking people
Human Immune Response to Ixodes Scapularis Tick Bites
Where
Bethesda
Age
18 years to 99 years
People
60
Run by
National Institute of Allergy and Infectious Diseases (NIAID)
See details and how to joinNCT05036707
No phaseTaking people
Navigating Pregnancy and Parenthood With Lyme Disease
Where
Washington D.C.
Age
18 years and over
People
30
Run by
Children's National Research Institute
See details and how to joinNCT06397794
No phaseTaking people
Pregnancy and Early Neurodevelopmental Outcomes Following In Utero Lyme Disease Exposure
Where
Washington D.C.
Age
18 years and over
People
40
Run by
Children's National Research Institute
See details and how to joinNCT06026969
No phaseTaking people
taVNS for Persistent Symptoms From Lyme Disease
Where
New York
Age
18 years to 65 years
People
24
Run by
Columbia University
See details and how to joinNCT05776251
No phaseTaking people
Transcranial Direct Current Stimulation for Post Treatment Lyme Disease
Where
New York, San Francisco
Age
18 years to 70 years
People
110
Run by
Columbia University
See details and how to joinNCT06915324
Phase 3Taking people
A Study to Learn About the Safety, Tolerability, and Immunogenicity of a Fifth Dose of 6-Valent OspA-Based Lyme Disease Vaccine
Where
Bangor, Burlington, Cortland, Duncansville, East Greenwich, Erie, Flemington, Horseheads, Pittsburgh, Sayre, Scottdale, Scranton, Smithfield, Uniontown, Winchester, Worcester
Age
7 years and over
People
1,712 worldwide
Run by
Pfizer
See details and how to joinNCT07500506
Early phase 1Taking people
Ceftriaxone Pulse Dose for Post-Treatment Lyme Disease
Where
East Syracuse
Age
18 years to 75 years
People
44
Run by
State University of New York - Upstate Medical University
See details and how to joinNCT06611111
Phase 1/2Taking people
Lumbrokinase for Adults With Long Covid, Post-treatment Lyme Disease Syndrome, and Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
Where
New York
Age
18 years and over
People
120
Run by
Icahn School of Medicine at Mount Sinai
See details and how to joinNCT06511050
No phaseTaking people
Rheumatology Patient Registry and Biorepository
Where
New Haven
Age
18 years to 99 years
People
5,000
Run by
Yale University
See details and how to joinNCT04402086
No phaseTaking people
Unhide® Project: A Digital Health Platform to Collect Lifestyle Data for Brain Inflammation Research
Where
Delafield
Age
2 years and over
People
10,000
Run by
Brain Inflammation Collaborative
See details and how to joinNCT04806620
No phaseNot yet taking people in United States
Safety and Effectiveness of the BlinkER System in Participants With Facial Nerve Palsy
Where
Deerfield Beach
Age
22 years to 120 years
People
80
Run by
Neurotrigger Ltd
See details and how to joinNCT06542289