Mantle cell lymphoma trials in United States

In United States 82 Also abroad 151

82 trials · From ClinicalTrials.gov, checked 14 November 2026. Ask the study team whether a trial fits you.

No phaseEnrolling by invitation
Continuous Temperature Monitoring (CTM) for Cytokine Release Syndrome (CRS), an Immune-Related Adverse Event
Where
Bethesda
Age
18 years to 120 years
People
136
Run by
National Cancer Institute (NCI)
See details and how to joinNCT07499128
Phase 2Taking people
Donor Stem Cell Transplant With Treosulfan, Fludarabine, and Total-Body Irradiation for the Treatment of Hematological Malignancies
Where
Seattle
Age
6 months and over
People
60
Run by
Fred Hutchinson Cancer Center
See details and how to joinNCT04195633
Phase 2Taking people
Phase II Study of Pirtobrutinib With Venetoclax In Relapsed-Refractory MCL (Mantle Cell Lymphoma) Patients
Where
Houston
Age
18 years and over
People
30
Run by
M.D. Anderson Cancer Center
See details and how to joinNCT05529069
Phase 1Taking people
Zanubrutinib in Combination With Sonrotoclax for the Treatment of Underrepresented Ethnic and Racial Minorities With Relapsed or Refractory B-cell Non-Hodgkin Lymphoma
Where
Duarte
Age
18 years and over
People
37
Run by
City of Hope Medical Center
See details and how to joinNCT06859008
Phase 1/2Taking people
The OPAL Study: AVM0703 for Treatment of Lymphoid Malignancies
Where
Canton, Chicago, Dallas, Duarte, Los Angeles, Louisville, Memphis, Omaha, Weeki Wachee, Whittier
Age
12 years to 95 years
People
144
Run by
AVM Biotechnology Inc
See details and how to joinNCT04329728
Phase 1/2Taking people
Autologous Stem Cell Transplant Followed by Polatuzumab Vedotin in Patients With B-cell Non-Hodgkin and Hodgkin Lymphoma
Where
Valhalla
Age
12 years to 70 years
People
20
Run by
New York Medical College
See details and how to joinNCT04491370
Phase 1Taking people
SynKIR-310 for Relapsed/Refractory B-NHL
Where
Atlanta, Denver, Fairway, New Brunswick, Philadelphia
Age
18 years and over
People
36
Run by
Verismo Therapeutics
See details and how to joinNCT06544265
Phase 1Taking people
A Study of NX-2127 in Adults With Relapsed/Refractory B-cell Malignancies
Where
Bethesda, Chicago, Cincinnati, Columbus, Dallas, Denver, Duarte, Houston, Miami Beach, Nashville, New York, Orange, Salt Lake City, San Francisco, Sarasota, Seattle
Age
18 years and over
People
248
Run by
Nurix Therapeutics, Inc.
See details and how to joinNCT04830137
Phase 2Taking people
Nemtabrutinib With Rituximab for the Treatment of Patients With Mantle Cell Lymphoma
Where
Duarte, Irvine
Age
18 years and over
People
27
Run by
City of Hope Medical Center
See details and how to joinNCT06572618
No phaseTaking people
Evaluation of Hypertension Management and Cardiovascular Adverse Event Prevention in Patients With B-cell Malignancies Undergoing Treatment With Bruton Tyrosine Kinase Inhibitors, the HALT Study
Where
Rochester
People
100
Run by
Mayo Clinic
See details and how to joinNCT06151730
Phase 1/2Taking people
CAR-20/19-T Cells in Patients With Relapsed Refractory B Cell Malignancies
Where
Milwaukee
Age
18 years to 80 years
People
100
Run by
Medical College of Wisconsin
See details and how to joinNCT04186520
Phase 1Taking people
Genetically Modified T-cells (CMV-Specific CD19-CAR T-cells) Plus a Vaccine (CMV-MVA Triplex) Following Stem Cell Transplantation for the Treatment of Intermediate or High Grade B-cell Non-Hodgkin Lymphoma
Where
Duarte
Age
18 years and over
People
15
Run by
City of Hope Medical Center
See details and how to joinNCT05432635
Phase 2Taking people
BRAZAN: A Randomized Phase 2 Study of Bendamustine, Rituximab, Cytarabine (AraC) Induction With Zanubrutinib (BRAZAN) Followed by Zanubrutinib/Rituximab +/- Sonrotoclax Maintenance in Treatment-Naïve Mantle Cell Lymphoma
Where
Boston, New York, Phoenix, Rochester, St Louis
Age
18 years and over
People
60
Run by
Christine Ryan
See details and how to joinNCT06854003
Phase 1Taking people
Study of Oral Administration of LP-168 in Patients With Relapsed or Refractory B-cell Malignancies.
Where
Cincinnati, Columbus, Durham, Salt Lake City
Age
18 years and over
People
60
Run by
Newave Pharmaceutical Inc
See details and how to joinNCT04775745
Phase 1Taking people
Study of SGR-1505 in Mature B-Cell Neoplasms
Where
Boston, Buffalo, Canton, Columbus, Dallas, Durham, Gilbert, Hackensack, Milwaukee, Newark, New York, Pompano Beach, Portland, Providence, Seattle, The Bronx
Age
18 years and over
People
98 worldwide
Run by
Schrödinger, Inc.
See details and how to joinNCT05544019 · EU 2023-505204-34-00
Phase 1Taking people
B-Cell Activating Factor Receptor (BAFFR)-Based Chimeric Antigen Receptor T-Cells With Fludarabine and Cyclophosphamide Lymphodepletion for the Treatment of Relapsed or Refractory B-cell Hematologic Malignancies
Where
Jacksonville
Age
18 years and over
People
27
Run by
Mayo Clinic
See details and how to joinNCT06191887
No phaseTaking people
CONFIRM: Magnetic Resonance Guided Radiation Therapy
Where
Boston
Age
18 years and over
People
70
Run by
Brigham and Women's Hospital
See details and how to joinNCT04368702
Phase 2Taking people
Acalabrutinib and Obinutuzumab for the Treatment of Previously Untreated Follicular Lymphoma or Other Indolent Non-Hodgkin Lymphomas
Where
Atlanta
Age
18 years and over
People
49
Run by
Emory University
See details and how to joinNCT04883437
Phase 1/2Taking people
Glofitamab Plus Ibrutinib With Obinutuzumab for the Treatment of Patients With Mantle Cell Lymphoma, IGNITE MCL Trial
Where
Portland
Age
18 years and over
People
27
Run by
OHSU Knight Cancer Institute
See details and how to joinNCT06357676
Phase 1/2Taking people
Avo In R/R And Previously Untreated MCL
Where
Boston, Chicago
Age
18 years and over
People
72
Run by
Austin I Kim
See details and how to joinNCT04855695
Phase 1Taking people
Study of Kappa Chimeric Antigen Receptor (CAR) T Lymphocytes Co-Expressing the Kappa and CD28 CARs for Relapsed/Refractory Kappa+ Non-Hodgkin Lymphoma and Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma.
Where
Chapel Hill
Age
18 years and over
People
20
Run by
UNC Lineberger Comprehensive Cancer Center
See details and how to joinNCT04223765
Phase 1Taking people
A Dose Escalation and Dose Expansion Study of Intratumoral ONM-501 Alone and in Combination With Cemiplimab in Patients With Advanced Solid Tumors and Lymphomas.
Where
Canton, Columbus, Dallas, Fairfax, Houston, Los Angeles, Pittsburgh, Tamarac
Age
18 years and over
People
168 worldwide
Run by
OncoNano Medicine, Inc.
See details and how to joinNCT06022029
Phase 1Taking people
AS-1763 in Patients With Previously Treated CLL/SLL or Non-Hodgkin Lymphoma
Where
Baltimore, Chicago, Durham, Fort Wayne, Houston, Maumee, Miami Beach, Milwaukee, Orange, Tampa, Westbury, Worcester
Age
18 years and over
People
120
Run by
Carna Biosciences, Inc.
See details and how to joinNCT05602363
Phase 1/2Taking people
A Safety and Efficacy Study Evaluating CTX112 in Subjects With Relapsed or Refractory B-Cell Malignancies
Where
Salt Lake City, San Antonio, St Louis, Westwood
Age
18 years and over
People
120 worldwide
Run by
CRISPR Therapeutics AG
See details and how to joinNCT05643742
No phaseTaking people
Long-term Follow-up Study of Patients Receiving CAR-T Cells
Where
Milwaukee
Age
18 years to 80 years
People
500
Run by
Medical College of Wisconsin
See details and how to joinNCT03375619