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Melanoma trials in United States

46 of 268 trials · From ClinicalTrials.gov, checked 14 November 2026. Ask the study team whether a trial fits you.

  • No phaseNot yet taking people in United States
    Clinical Genetics Branch Eligibility Screening Survey
    Where
    Rockville
    Age
    1 year to 99 years
    People
    1,000
    Run by
    National Cancer Institute (NCI)
  • No phaseEnrolling by invitation
    Natural History Study of Early Life Exposures in Agriculture (ELEA)
    Where
    Bethesda
    Age
    18 years to 99 years
    People
    64,277
    Run by
    National Cancer Institute (NCI)
  • No phaseTaking people
    Evaluation for NCI Surgery Branch Clinical Research Protocols
    Where
    Bethesda
    Age
    18 years and over
    People
    7,000
    Run by
    National Cancer Institute (NCI)
  • No phaseEnrolling by invitation
    Harvesting Cells for Experimental Cancer Treatments
    Where
    Bethesda
    Age
    18 years and over
    People
    7,000
    Run by
    National Cancer Institute (NCI)
  • No phaseEnrolling by invitation
    Follow Up Protocol for Subjects Previously Enrolled on NCI Surgery Branch Studies
    Where
    Bethesda
    Age
    18 years and over
    People
    1,150
    Run by
    National Cancer Institute (NCI)
  • No phaseTaking people
    Testing of an Educational Tool for Patients With Melanoma and Pre-Existing Autoimmune Disease Who Are Candidates for Immune Checkpoint Inhibitors
    Where
    Houston
    Age
    18 years and over
    People
    125
    Run by
    M.D. Anderson Cancer Center
  • No phaseTaking people
    BostonGene and Exigent Genomic INsight Study
    Where
    Albuquerque, Houston, Puyallup, Rogers, Stockton, Tulsa
    Age
    18 years and over
    People
    400
    Run by
    BostonGene
  • No phaseTaking people
    Symptoms of Immune Checkpoint Inhibitor Therapy in Cutaneous Melanoma
    Where
    San Francisco
    Age
    18 years and over
    People
    300
    Run by
    University of California, San Francisco
  • No phaseTaking people
    Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection
    Where
    Aberdeen, Aitkin, Akron, Albert Lea, Albuquerque, Allentown, Alma, Alpena, Alton, Amarillo, Ames, Anaconda, Anchorage, Anderson, Ankeny, Ann Arbor, Antigo, Appleton, Arroyo Grande, Asheville, Ashland, Augusta, Aurora, Aventura, Baker City, Bakersfield, Ballwin, Baltimore, Baraboo, Barberton, Bardstown, Barrington, Baton Rouge, Battle Creek, Baxter, Beavercreek, Belfast, Bellingham, Belpre, Bemidji, Bend, Berlin, Bethesda, Bethlehem, Biddeford, Billings, Bismarck, Bloomington, Boardman, Boise, Bolivar, Bonita Springs, Boone, Boulder, Bozeman, Brainerd, Branson, Braselton, Brewer, Brighton, Brownstown, Brunswick, Bryan, Burbank, Burien, Burlington, Burnsville, Caldwell, Cambridge, Canton, Cape Girardeau, Carbondale, Carmichael, Caro, Carson City, Carterville, Carthage, Cary, Cedar Rapids, Centennial, Centerville, Centralia, Chaska, Chelsea, Chesapeake, Chesterfield, Cheyenne, Chicago, Chillicothe, Cincinnati, Clackamas, Clarkston, Clearwater, Clinton, Clinton Township, Clive, Clyde, Cody, Coeur d'Alene, Colorado Springs, Columbia, Columbus, Concord, Coon Rapids, Coos Bay, Corbin, Council Bluffs, Creston, Crosslake, Crystal Lake, Cudahy, Danville, Dayton, Dearborn, Decatur, Deerfield Beach, Deer River, Delaware, Denver, Des Moines, Detroit, Detroit Lakes, Dixon, Downers Grove, Dublin, Duluth, Durango, Durham, East China Township, Easton, East Stroudsburg, Eau Claire, Edgewood, Edina, Edmonds, Effingham, Elgin, Elk Grove, Elmhurst, Elmira, Ely, Emeryville, Emmett, Englewood, Enumclaw, Eureka, Everett, Evergreen Park, Fairbanks, Fargo, Farmington, Farmington Hills, Federal Way, Findlay, Fishersville, Flint, Florence, Fond du Lac, Fort Collins, Fort Dodge, Fort Lauderdale, Fort Myers, Fort Smith, Fort Thomas, Fosston, Franklin, Freehold, Fridley, Fruitland, Gaffney, Gahanna, Gainesville, Galesburg, Garden City, Garner, Georgetown, Germantown, Gladwin, Glen Burnie, Glens Falls, Goldsboro, Grafton, Grand Forks, Grand Island, Grand Rapids, Great Bend, Great Falls, Greeley, Green Bay, Greenville, Greenwood, Greer, Grosse Pointe Woods, Grove City, Hackettstown, Harvey, Havre, Hayward, Hazel Crest, Hazleton, Helena, Henderson, Hendersonville, Hibbing, Hood River, Houma, Houston, Huntington, International Falls, Issaquah, Jackson, Jacksonville, Jamaica, Jamaica Plain, Jamestown, Janesville, Jefferson, Jefferson City, Joplin, Kalamazoo, Kalispell, Kansas City, Kearney, Kennewick, Kenosha, Kettering, Kewanee, Kingman, Lacey, La Crosse, Lakeland, Lakewood, Lancaster, Lansing, Laredo, Las Cruces, Las Vegas, Leavenworth, Lewisburg, Lexington, Libertyville, Lima, Lincoln, Little Rock, Littleton, Livonia, Loma Linda, London, Lone Tree, Long Beach, Longmont, Longview, Loveland, Macomb, Madison, Manchester, Mankato, Mansfield, Maple Grove, Maplewood, Marietta, Marinette, Marion, Marlette, Marrero, Marshalltown, Martinez, Marysville, Mattoon, Meadowbrook, Mechanicsville, Medford, Medina, Merced, Meridian, Metairie, Miami Beach, Midland, Midlothian, Milwaukee, Minneapolis, Minot, Missoula, Moline, Monticello, Moose Lake, Morristown, Mount Pleasant, Mount Sterling, Mount Vernon, Mukwonago, Mullica Hill, Murrells Inlet, Muskegon, Nags Head, Nampa, Napa, Neenah, New Albany, Newark, Newberg, New Brunswick, New London, New Orleans, New Richmond, Newton, New Ulm, New York, Niles, Norfolk, Normal, Norton Shores, Novi, Oakland, Oak Lawn, Ocean Pines, Oconomowoc, Oconto Falls, O'Fallon, Oklahoma City, Olney, Omaha, Ontario, Oregon City, Osage Beach, Oshkosh, Ottawa, Paducah, Pahrump, Papillion, Parker, Park Rapids, Park Ridge, Pekin, Pennington, Peoria, Pequot Lakes, Perrysburg, Peru, Phoenix, Phoenixville, Pine River, Pittsburg, Plant City, Pompton, Pontiac, Portland, Portsmouth, Port Townsend, Post Falls, Pottstown, Princeton, Providence, Pueblo, Racine, Raleigh, Rancho Mirage, Randallstown, Reading, Redmond, Reed City, Reno, Renton, Rhinelander, Richmond, Rio Rancho, Robbinsdale, Rockford, Rocklin, Rockport, Rolla, Royal Oak, Sacramento, Safety Harbor, Saginaw, Saint Cloud, Sainte Genevieve, Saint Joseph, Saint Louis Park, Saint Paul, Salisbury, San Antonio, Sandpoint, Sandstone, Sanford, San Luis Obispo, Santa Cruz, Santa Maria, Santa Rosa, Savannah, Scarborough, Seattle, Sedro-Woolley, Shakopee, Shawano, Sheboygan, Shelton, Sheridan, Silverdale, Sioux Falls, Southfield, South Portland, Spartanburg, Spokane, Spooner, Springfield, Staples, Sterling Heights, Stevens Point, St. Helena, Stillwater, St Louis, Stockton, Stony Brook, St. Petersburg, Sturgeon Bay, Sullivan, Summit, Superior, Tacoma, Tampa, Tawas City, Thief River Falls, Thornton, Tifton, Toledo, Topeka, Towson, Traverse City, Troy, Twin Falls, Two Rivers, Union, Urbana, Vancouver, Vineland, Virginia, Virginia Beach, Waconia, Walla Walla, Walnut Creek, Warren, Warwick, Washington, Washington D.C., Waukee, Waukesha, Waupaca, Wausau, Wauwatosa, Weaverville, West Allis, West Bloomfield, West Branch, West Columbia, West Des Moines, Westerville, West Haven, Westminster, West Reading, Wichita, Wilkes-Barre, Willmar, Wilmington, Winter Haven, Wisconsin Rapids, Woodbury, Woodland, Worthington, Wyandotte, Wyoming, Yakima, Yelm, Yorkville, Youngstown, Ypsilanti, Zanesville
    Age
    40 years to 75 years
    People
    2,900
    Run by
    Alliance for Clinical Trials in Oncology
  • No phaseTaking people
    Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics
    Where
    ‘Aiea, Albemarle, Albert Lea, Albuquerque, Allentown, Alma, Alpena, Alton, Anaconda, Anderson, Ankeny, Ann Arbor, Antigo, Antioch, Appleton, Arroyo Grande, Asheboro, Ashland, Atlanta, Augusta, Aurora, Baker City, Ballwin, Baltimore, Bardstown, Barrington, Battle Creek, Beaufort, Beavercreek, Belfast, Bellevue, Bellingham, Belpre, Berlin, Berlin Corners, Bethlehem, Bettendorf, Biddeford, Billings, Bloomington, Bluffton, Boardman, Boiling Springs, Boise, Boulder, Bozeman, Brainerd, Brookfield, Brunswick, Burlington, Burnsville, Caldwell, Canton, Carmichael, Carterville, Carthage, Cedar Rapids, Centennial, Centralia, Chambersburg, Charleston, Charlotte, Chaska, Chicago, Chilton, Chippewa Falls, Clearwater, Clemmons, Clive, Coeur d'Alene, Collierville, Colorado Springs, Columbus, Concord, Coon Rapids, Crystal Lake, Cudahy, Danville, Dayton, Decatur, Deer River, Denver, Des Moines, Detroit Lakes, Dickson City, Dixon, Downers Grove, Dublin, Duluth, Easley, East Stroudsburg, Eau Claire, Edina, Edmonds, Effingham, Elgin, Elk Grove, Elkton, Englewood, Ephrata, Escanaba, Eureka, ‘Ewa Beach, Fairbanks, Fargo, Farmington, Findlay, Fishersville, Flint, Florence, Forest City, Fort Smith, Fosston, Franklin, Fredericksburg, Freehold, Fremont, Fresno, Gaffney, Galesburg, Gastonia, Georgetown, Germantown, Gettysburg, Gladwin, Glen Burnie, Glens Falls, Grafton, Grand Rapids, Great Falls, Green Bay, Greensboro, Greenville, Greer, Grenada, Hackettstown, Havre, Hays, Hayward, Hazel Crest, Hazleton, Henderson, Hibbing, High Point, Hilton Head Island, Hinesville, Honolulu, Huntersville, Huntington, Iowa City, Iron Mountain, Issaquah, Jamaica, Jesup, Jonesboro, Joplin, Kalamazoo, Kalispell, Kansas City, Kearney, Kennewick, Kenosha, Kettering, Kewanee, Kingman, La Crosse, Ladysmith, Lafayette, Lakewood, Lancaster, Las Cruces, Las Vegas, Lawrence, Lawrenceville, Lebanon, Lee's Summit, Lewisburg, Lexington, Libertyville, Lihue, Lincolnton, Littleton, London, Lone Tree, Longmont, Lynchburg, Macomb, Macon, Madison, Mankato, Maplewood, Marinette, Marshfield, Martinez, Martinsville, Marysville, Matthews, Mattoon, Medford, Memphis, Mequon, Michigan City, Midland, Millville, Milwaukee, Minneapolis, Minocqua, Missoula, Modesto, Monroe, Monticello, Morristown, Mount Pleasant, Mount Sterling, Mount Vernon, Murrells Inlet, Muskegon, Nampa, Neenah, Neillsville, New Albany, Newark, New London, New Richmond, Newton, New Ulm, New York, Normal, Norton Shores, Oakland, Oak Lawn, Oconto Falls, O'Fallon, Oklahoma City, Olathe, Ontario, Orangeburg, Osage Beach, Oshkosh, Oswego, Ottawa, Overland Park, Oxford, Paducah, Palos Heights, Park Rapids, Park Ridge, Pekin, Peoria, Peru, Phoenix, Plant City, Pompton, Pontiac, Portland, Port Townsend, Post Falls, Pottsville, Princeton, Pueblo, Racine, Rapid City, Redwood City, Reed City, Rehoboth Beach, Reidsville, Rhinelander, Rice Lake, Richmond, Rio Rancho, Roanoke, Robbinsdale, Rochester, Rockford, Rock Hill, Rocklin, Rockport, Roseville, Sacramento, Saginaw, Saint Cloud, Sainte Genevieve, Saint Joseph, Saint Louis Park, Saint Paul, Salina, Sandpoint, Sandstone, Sanford, San Francisco, San Jose, San Leandro, San Luis Obispo, San Rafael, Santa Clara, Santa Maria, Santa Rosa, Savannah, Scarborough, Scranton, Seattle, Sedro-Woolley, Seneca, Shakopee, Shawano, Sheboygan, Shelby, Shreveport, Southaven, South Hill, South Portland, South San Francisco, Spartanburg, Spooner, Springfield, Stevens Point, St. Helena, Stillwater, St Louis, Stockton, St. Petersburg, Sturgeon Bay, Sullivan, Summit, Sunset Hills, Syracuse, Tampa, Tawas City, Teaneck, The Bronx, Thornton, Topeka, Towson, Traverse City, Two Rivers, Union, Urbana, Vacaville, Vallejo, Verona, Virginia, Waconia, Walla Walla, Walnut Creek, Warren, Washington, Waukee, Waupaca, Wausau, Wauwatosa, West Allis, Westminster, Weston, Westwood, Wilkes-Barre, Willmar, Winchester, Winston-Salem, Winter Haven, Wisconsin Rapids, Woodbury, Woodland, Wyoming, York, Yorkville, Youngstown
    Age
    18 years and over
    People
    2,000 worldwide
    Run by
    Wake Forest University Health Sciences
  • No phaseTaking people
    Clinical, Laboratory, and Epidemiologic Characterization of Individuals and Families at High Risk of Melanoma
    Where
    Bethesda
    Age
    4 weeks to 99 years
    People
    3,000
    Run by
    National Cancer Institute (NCI)
  • No phaseTaking people
    Cancer Experience Registry (CER) for Cancer Patients and Caregivers
    Where
    Washington D.C.
    Age
    18 years and over
    People
    15,000
    Run by
    Cancer Support Community, Research and Training Institute, Philadelphia
  • No phaseEnrolling by invitation
    Community Based Strategies for Early Detection of Melanoma
    Where
    Los Angeles
    Age
    18 years and over
    People
    200
    Run by
    Cedars-Sinai Medical Center
  • No phaseTaking people
    Frequency and Clinical Phenotype of BAP1 Hereditary Predisposition Syndrome
    Where
    Columbus
    People
    500
    Run by
    Mohamed Abdel-Rahman
  • No phaseEnrolling by invitation
    Prospective Procurement of Tumor Tissue to Identify Novel Therapeutic Targets and Study the Tumor Microenvironment
    Where
    Bethesda
    Age
    18 years and over
    People
    1,200
    Run by
    National Cancer Institute (NCI)
  • No phaseTaking people
    Well-Being and Health-Related Quality of Life in Melanoma Patients During COVID-19 Pandemic
    Where
    Houston
    People
    1,152
    Run by
    M.D. Anderson Cancer Center
  • No phaseTaking people
    DESTINY-PANTUMOUR04
    Where
    Birmingham, Boulder, Bullhead City, Canton, Casa Grande, Coral Springs, Dallas, Decatur, Durham, Farmington, Maumee, Nashville, Philadelphia, San Diego, St. Petersburg, Topeka, West Palm Beach, Wilson
    Age
    18 years to 130 years
    People
    100
    Run by
    AstraZeneca
  • No phaseTaking people
    Pan-tumor MRD Study
    Where
    Atlanta, Binghamton, Birmingham, Bullhead City, Canton, Casa Grande, Charlotte, Coral Springs, Corbin, Covington, Elizabethtown, Englewood, Farmington, Glendale, Goldsboro, Grand Rapids, Houston, Kingwood, Lancaster, Lexington, Lincoln, Little Rock, Louisville, Maumee, O'Fallon, Orange City, Oxnard, Portland, Richmond, Rochester, San Diego, Sayre, Shirley, Shreveport, Springdale, Springfield, Stockton, St. Petersburg, Tacoma, Texarkana, Topeka, Tulsa, Urbana, Wichita, Wilson, York
    Age
    18 years and over
    People
    1,350
    Run by
    Paradigm Health
  • No phaseTaking people
    ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation
    Where
    Appleton, Aurora, Birmingham, Boston, Broomall, Chandler, Chapel Hill, Cincinnati, Cleveland, Dallas, East Brunswick, Edinburg, Forth Worth, Grand Rapids, Hollywood, Hot Springs, La Jolla, Lakeland, Lewiston, Myrtle Beach, New Orleans, Newport Beach, New York, Philadelphia, Redwood City, Rochester, Rock Hill, Sacramento, Salt Lake City, San Antonio, Shreveport, Toledo, York
    Age
    18 years and over
    People
    2,285 worldwide
    Run by
    Guardant Health, Inc.
  • No phaseTaking people
    Molecular Testing for the MD Anderson Cancer Center Personalized Cancer Therapy Program
    Where
    Houston
    People
    12,000
    Run by
    M.D. Anderson Cancer Center
  • Phase 3Enrolling by invitation
    A Long-Term Follow-Up Study of Subjects Completing the AU-011-301(CoMpass) for Early Choroidal Melanoma
    Where
    Ann Arbor, Austin, Greenville, Madison, Nashville, Oklahoma City, Rochester, Sacramento, Salt Lake City, Southlake
    Age
    18 years and over
    People
    100 worldwide
    Run by
    Aura Biosciences
    See details and how to joinNCT07338968 · EU 2025-524405-33-00
  • No phaseTaking people
    Digital Remote Monitoring of Immune Checkpoint Inhibitor Therapy Induced Toxicity Using the Vigilant App
    Where
    Rochester
    Age
    18 years and over
    People
    100
    Run by
    Mayo Clinic
  • No phaseTaking people
    Integrated Cancer Repository for Cancer Research
    Where
    Aitkin, Alliance, Aurora, Bozeman, Brainerd, Canton, Council Bluffs, Daytona Beach, DeLand, Duluth, Fargo, Fayetteville, Fergus Falls, Fort Wayne, Glens Falls, Green Bay, Greenwood Village, Hastings, Holyoke, Kansas City, Liberty, Manchester, Minot, Norfolk, North Kansas City, North Platte, Omaha, Orange City, Overland Park, Palm Coast, Randallstown, Saint Joseph, Tallahassee, Utica, Waterloo, Westminster, Yorkville
    Age
    19 years to 110 years
    People
    999,999
    Run by
    University of Nebraska
  • No phaseTaking people
    Predicting Response to Immunotherapy From Analysis of Live Tumor Biopsies (ELEPHAS-05)
    Where
    Forth Worth, Fort Smith, Frederick, Oklahoma City, Springfield, St Louis, Temple
    Age
    18 years and over
    People
    2,000
    Run by
    Elephas
  • No phaseTaking people
    Studying Off Label Insurance Coverage for Patients With Cutaneous Cancers a "Filter" Observational Study
    Where
    Columbus
    Age
    18 years and over
    People
    70
    Run by
    Ohio State University Comprehensive Cancer Center
Under construction, not live – Melanoma trials in United States – Frontlight Research