Mesothelioma trials in United States

In United States 54 Also abroad 104

54 trials · From ClinicalTrials.gov, checked 11 November 2026. Ask the study team whether a trial fits you.

Phase 1/2Taking people
TT-4 and TT-10 as Single Agents and in Combination in Subjects With Advanced Selected Solid Tumors and Pleural Mesothelioma
Where
Houston, Los Angeles
Age
18 years and over
People
35
Run by
Portage Biotech
See details and how to joinNCT04969315
Phase 2Taking people
Study of Volrustomig as Monotherapy or in Combination With Anti- Cancer Agents in Participants With Advanced/Metastatic Solid Tumors
Where
Baltimore, Columbus, Los Angeles, New York, Philadelphia, Stony Brook
Age
18 years to 64 years
People
257 worldwide
Run by
AstraZeneca
See details and how to joinNCT06535607 · EU 2025-523947-36-00
Phase 1/2Taking people
Safety and Tolerability of TNG462 in Patients With MTAP-deleted Solid Tumors
Where
Boston, Chicago, Detroit, Fairfax, Grand Junction, Houston, Lake Mary, Miami, Nashville, New York, Palo Alto, Salt Lake City, Urbana, Zion
Age
18 years and over
People
225 worldwide
Run by
Tango Therapeutics, Inc.
See details and how to joinNCT05732831
Phase 1Taking people
Phase 1 Study of MRTX1719 in Solid Tumors With MTAP Deletion
Where
Brookline, Chapel Hill, Chicago, Dallas, Fairfax, Fort Worth, Grand Rapids, Houston, Jacksonville, Lone Tree, Milwaukee, Mineola, Nashville, New Brunswick, New York, Norton Shores, Orlando, Phoenix, Port Jefferson Station, Rochester, San Antonio, Seattle, Tyler
Age
18 years and over
People
336
Run by
Bristol-Myers Squibb
See details and how to joinNCT05245500
Phase 1/2Taking people
A Study of Tulmimetostat DZR123 (CPI-0209) in Patients With Advanced Solid Tumors and Lymphomas
Where
Ann Arbor, Atlanta, Baltimore, Boston, Buffalo, Charlottesville, Chicago, Cincinnati, Grand Rapids, Hackensack, Maywood, New York, Philadelphia, Rochester, San Antonio, Seattle, Tampa, The Bronx
Age
18 years and over
People
300 worldwide
Run by
Novartis Pharmaceuticals
See details and how to joinNCT04104776 · EU 2023-508002-20-00
Phase 2Taking people
Testing the Addition of Immunotherapy Before Surgery for Patients With Sarcomatoid Mesothelioma
Where
Aberdeen, Anchorage, Arroyo Grande, Aurora, Bellevue, Bellingham, Bend, Boise, Burbank, Carson City, Centralia, Chadds Ford, Chicago, Clackamas, Coos Bay, Dallas, Danville, DeKalb, Durham, Edmonds, Effingham, Elkton, Everett, Fort Worth, Fruitland, Geneva, Glenview, Grayslake, Henderson, Hood River, Issaquah, Jacksonville, Kennewick, Kingman, Lacey, La Jolla, Lake Forest, Las Vegas, Lewes, Longview, Mattoon, Meridian, Millville, Minneapolis, Missoula, Mount Vernon, Nampa, Napa, Newark, Newberg, Oregon City, Orland Park, Pahrump, Phoenix, Portland, Raleigh, Redmond, Rehoboth Beach, Reno, Renton, Richardson, Rochester, Santa Rosa, Scottsdale, Seattle, Sedro-Woolley, Shelton, Spokane, Twin Falls, Urbana, Vancouver, Walla Walla, Warrenville, Wilmington, Yakima, Yelm, Yorkville
Age
18 years and over
People
26
Run by
Alliance for Clinical Trials in Oncology
See details and how to joinNCT05647265
Phase 1Taking people
Fast TILs to Treat Metastatic Cancer Patients With Pleural Disease
Where
Pittsburgh
Age
18 years to 79 years
People
10
Run by
David Bartlett, MD
See details and how to joinNCT07192900
No phaseTaking people
Integrated Cancer Repository for Cancer Research
Where
Aitkin, Alliance, Aurora, Bozeman, Brainerd, Canton, Council Bluffs, Daytona Beach, DeLand, Duluth, Fargo, Fayetteville, Fergus Falls, Fort Wayne, Glens Falls, Green Bay, Greenwood Village, Hastings, Holyoke, Kansas City, Liberty, Manchester, Minot, Norfolk, North Kansas City, North Platte, Omaha, Orange City, Overland Park, Palm Coast, Randallstown, Saint Joseph, Tallahassee, Utica, Waterloo, Westminster, Yorkville
Age
19 years to 110 years
People
999,999
Run by
University of Nebraska
See details and how to joinNCT02012699
Phase 1Taking people
SynKIR-110 for Mesothelin Expressing Ovarian Cancer, Cholangiocarcinoma or Mesothelioma
Where
Houston, Madison, Philadelphia, Tampa, Westwood
Age
18 years and over
People
42
Run by
Verismo Therapeutics
See details and how to joinNCT05568680
Phase 1/2Taking people
A Study to Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression
Where
Columbus, Gilbert, Jacksonville, La Jolla, Los Angeles, Nashville, New York, Rochester, Seattle, Stanford, St Louis, Tampa
Age
18 years and over
People
474
Run by
A2 Biotherapeutics Inc.
See details and how to joinNCT06051695
Phase 2Taking people
A Study of Sacituzumab Govitecan in People With Mesothelioma
Where
Basking Ridge, Commack, Harrison, Middletown, Montvale, New York, Uniondale
Age
18 years and over
People
33
Run by
Memorial Sloan Kettering Cancer Center
See details and how to joinNCT06477419
No phaseEnrolling by invitation
A Long-Term Follow-Up Study of Participants Treated With A2 Biotherapeutics (A2 Bio) Gene Therapy (GT) Products
Where
Gilbert, New York, Rochester
Age
18 years and over
People
400
Run by
A2 Biotherapeutics Inc.
See details and how to joinNCT06885424
No phaseTaking people
Prospectively Collected Pleural Biopsies for Validation of Malignant Pleural Mesothelioma Prognostic Biomarkers
Where
Boston
Age
18 years and over
People
240
Run by
Dana-Farber Cancer Institute
See details and how to joinNCT03683680
Phase 1/2Taking people
A Study of Oral 7HP349 (Alintegimod) in Combination With Ipilimumab Followed by Nivolumab Monotherapy
Where
Aurora, Houston, Lake Mary, Lebanon, Providence
Age
18 years and over
People
126
Run by
7 Hills Pharma, LLC
See details and how to joinNCT06362369
Phase 1Taking people
A Study of VET3-TGI in Patients With Solid Tumors
Where
Dallas, Houston, Indianapolis, Los Angeles, Miami, Orange, Pittsburgh
Age
18 years and over
People
60
Run by
KaliVir Immunotherapeutics
See details and how to joinNCT06444815
Phase 1Taking people
Fast TILs to Treat Metastatic Pleural Effusions From Epithelial or Mesothelial Primary Tumors
Where
Pittsburgh
Age
18 years to 79 years
People
10
Run by
Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)
See details and how to joinNCT07443020
Phase 1/2Taking people
Study to Evaluate VT3989 in Patients With Metastatic Solid Tumors
Where
Arlington, Boston, Chicago, Houston, Minneapolis, New York, San Antonio, San Francisco
Age
18 years and over
People
434 worldwide
Run by
Vivace Therapeutics, Inc
See details and how to joinNCT04665206
No phaseTaking people
Partial Pleurectomy (Surgery) for Unresectable Pleural Mesothelioma
Where
Chicago
Age
18 years and over
People
30
Run by
University of Chicago
See details and how to joinNCT07126509
No phaseEnrolling by invitation
Molecular Analysis of Thoracic Malignancies
Where
Stanford
Age
18 years and over
People
1,000
Run by
Stanford University
See details and how to joinNCT01385722
Phase 1Taking people
Pembrolizumab in Combination With Chemotherapy and Image-Guided Surgery for Malignant Pleural Mesothelioma (MPM)
Where
Philadelphia
Age
18 years and over
People
20
Run by
Abramson Cancer Center at Penn Medicine
See details and how to joinNCT03760575
Phase 2Taking people
MAGIC AKI: Magnesium for the Prevention of HIOC-Associated AKI
Where
Boston
Age
18 years and over
People
130
Run by
Brigham and Women's Hospital
See details and how to joinNCT05730816
No phaseTaking people
Stereotactic Magnetic Resonance Guided Radiation Therapy
Where
Boston
Age
18 years and over
People
397
Run by
Dana-Farber Cancer Institute
See details and how to joinNCT04115254
No phaseTaking people
Clinical Utility of Portable Dynamic Chest X Ray (DDR) in the ICU
Where
Boston
Age
18 years and over
People
230
Run by
Brigham and Women's Hospital
See details and how to joinNCT06538376
No phaseTaking people
Tissue Procurement for Gastric Cancer, Gastrointestinal Stromal Tumors (GIST), Esophageal Cancer, Pancreas Cancer, Hepatocellular Cancer, Biliary Cancer, Neuroendocrine, Peritoneal Mesothelioma, Anal Cancer and Colorectal Cancer in Patients Undergoing Surgery or Biopsy
Where
Chicago
People
1,000
Run by
University of Chicago
See details and how to joinNCT01416714
Phase 1Taking people
A Study of NX-1607 in Adults With Advanced Malignancies
Where
Aurora, Chapel Hill, Charlottesville, Chicago, Duarte, Houston, Los Angeles, Oklahoma City, San Francisco, Seattle
Age
18 years and over
People
345 worldwide
Run by
Nurix Therapeutics, Inc.
See details and how to joinNCT05107674