Multiple sclerosis trials in Canada

In Canada 22 Also abroad 506

22 trials · From ClinicalTrials.gov, checked 11 November 2026. Ask the study team whether a trial fits you.

Phase 3Taking people
A Study of Orelabrutinib in Patients With Primary Progressive Multiple Sclerosis
Where
Vancouver
Age
18 years to 60 years
People
705 worldwide
Run by
Zenas BioPharma (USA), LLC
See details and how to joinNCT07067463 · EU 2025-524316-11-00
No phaseTaking people
Repetitive Transcranial Magnetic Stimulation (rTMS) in MS Induced Spastic Paraparesis
Where
Gatineau
Age
18 years to 70 years
People
70
Run by
Clinique Neuro-Outaouais
See details and how to joinNCT07159789
No phaseTaking people
Development of a Novel Functional Eye-Tracking Software Application for Multiple Sclerosis
Where
Montreal
Age
18 years and over
People
168
Run by
Innodem Neurosciences
See details and how to joinNCT05061953
Phase 2Taking people
A Study to Evaluate the Efficacy, Safety and Tolerability of BMS-986368 in Participants With Multiple Sclerosis Spasticity
Where
Edmonton, Lévis, London, Montreal, Ottawa, Toronto
Age
18 years to 70 years
People
200 worldwide
Run by
Celgene
See details and how to joinNCT06782490
Phase 3Taking people
Efficacy and Safety of Remibrutinib After Switching From Ocrelizumab in Participants Living With Relapsing Multiple Sclerosis.
Where
Edmonton, Lévis, Montreal, Vancouver
Age
40 years to 70 years
People
400 worldwide
Run by
Novartis Pharmaceuticals
See details and how to joinNCT06846281 · EU 2023-509275-17-00
Phase 1Taking people
Study of KITE-363 in Participants With Autoimmune Neurologic Diseases That Did Not Respond to Usual Treatment
Where
Montreal, Ottawa
Age
18 years to 75 years
People
57 worldwide
Run by
Kite, A Gilead Company
See details and how to joinNCT07304154
No phaseNot yet taking people in Canada
An Online Tailored Cognitive Therapy-Based Intervention for Depression in Multiple Sclerosis: ACTION-MS Online
Where
Toronto
Age
18 years and over
People
240 worldwide
Run by
University of Melbourne
See details and how to joinNCT07875309
Phase 3Taking people
A Study to Evaluate the Efficacy and Safety of Remibrutinib in Secondary Progressive Multiple Sclerosis
Where
Burnaby, Calgary, Edmonton, Halifax, Lévis, Montreal, Ottawa, Québec, Sherbrooke, Vancouver
Age
18 years to 65 years
People
1,275 worldwide
Run by
Novartis Pharmaceuticals
See details and how to joinNCT07225504
Phase 1Taking people
Testing an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Patients With Autoimmune Disorders, AIM-NIVO
Where
Toronto
Age
18 years and over
People
300 worldwide
Run by
National Cancer Institute (NCI)
See details and how to joinNCT03816345
Phase 2Taking people
Cannabis (THC vs. CBD) in Multiple Sclerosis
Where
Calgary
Age
26 years to 59 years
People
30
Run by
University of Calgary
See details and how to joinNCT06261489
Phase 1Taking people
An Open-label Study of AZD0120 in Adults With Multiple Sclerosis
Where
Montreal
Age
18 years to 60 years
People
24 worldwide
Run by
AstraZeneca
See details and how to joinNCT07224373
Phase 4Taking people
ELIOS - Investigational Biomarkers to Track Disease Modification in Active RRMS
Where
Burnaby, Calgary, Edmonton, Halifax, Montreal, Ottawa, Québec, Sherbrooke, St. John's, Vancouver
Age
18 years to 99 years
People
224
Run by
Novartis Pharmaceuticals
See details and how to joinNCT06733922
Phase 1Not yet taking people in Canada
Transcranial Magnetic Stimulation for Depression in Multiple Sclerosis
Where
Calgary
Age
18 years to 65 years
People
20
Run by
University of Calgary
See details and how to joinNCT07562074
No phaseTaking people
Innovative Approaches to Enhance Balance and Neuroplasticity in Multiple Sclerosis
Where
Toronto
Age
18 years to 65 years
People
24
Run by
University Health Network, Toronto
See details and how to joinNCT07174973
No phaseTaking people
Implementation of an App-based Walking Aid Skills Training Program
Where
Calgary, Québec
Age
18 years to 99 years
People
52
Run by
University of Calgary
See details and how to joinNCT05347875
Phase 1/2Taking people
A Phase I Double Blind Study of Metformin Acting on Endogenous Neural Progenitor Cells in Children and Young Adults With Multiple Sclerosis
Where
Toronto
Age
10 years to 25 years
People
20
Run by
The Hospital for Sick Children
See details and how to joinNCT04121468
No phaseNot yet taking people in Canada
Examination of a Self-Compassion Course for Healthcare Providers Working With People With Multiple Sclerosis
Where
Toronto
Age
18 years and over
People
40
Run by
Robert Simpson
See details and how to joinNCT07097402
Phase 2Taking people
Cannabis as a Complementary Treatment in Multiple Sclerosis
Where
Montreal
Age
21 years and over
People
250
Run by
Centre hospitalier de l'Université de Montréal (CHUM)
See details and how to joinNCT05092191
Phase 1Taking people
Deep Brain Stimulation for Refractory Trigeminal Neuralgia with a Pontine Lesion
Where
Sherbrooke
Age
18 years and over
People
6
Run by
Université de Sherbrooke
See details and how to joinNCT05451251
No phaseNot yet taking people in Canada
Implementation of Online Mindfulness-Based Stress Reduction Tailored for People with Multiple Sclerosis
Where
Toronto
Age
18 years to 60 years
People
120
Run by
Robert Simpson
See details and how to joinNCT06415552
No phaseTaking people
EMG Biofeedback Training to Improve Balance in Individuals with Multiple Sclerosis
Where
Hamilton
Age
18 years to 80 years
People
46
Run by
McMaster University
See details and how to joinNCT06461741
No phaseNot yet taking people in Canada
Remote Ischemic Conditioning in PPMS
Where
Calgary
Age
18 years to 65 years
People
45
Run by
University of Calgary
See details and how to joinNCT06171334