Neuroendocrine tumours trials in United States

In United States 89 Also abroad 244

89 trials · From ClinicalTrials.gov, checked 12 November 2026. Ask the study team whether a trial fits you.

Phase 2Taking people
Belzutifan/MK-6482 for the Treatment of Advanced Pheochromocytoma/Paraganglioma (PPGL), Pancreatic Neuroendocrine Tumor (pNET), Von Hippel-Lindau (VHL) Disease-Associated Tumors, Advanced Gastrointestinal Stromal Tumor (wt GIST), or Solid Tumors With HIF-2α Related Genetic Alterations (MK-6482-015)
Where
Ann Arbor, Baltimore, Bethesda, Boston, Chicago, Houston, Iowa City, Los Angeles, Nashville, New York, Philadelphia, St Louis, Warrenville
Age
12 years and over
People
355 worldwide
Run by
Merck Sharp & Dohme LLC
See details and how to joinNCT04924075 · EU 2023-504853-11-00
Phase 2Taking people
A UGT1A1 Genotype-Directed Study of Belinostat Pharmacokinetics and Toxicity
Where
Bethesda
Age
18 years to 120 years
People
60
Run by
National Cancer Institute (NCI)
See details and how to joinNCT06406465
Phase 3Taking people
DAREON®-NEC-1: A Study in People With Advanced Extrapulmonary Neuroendocrine Cancer (epNEC) to Compare Obrixtamig Plus Carboplatin and Etoposide Treatment With Standard Chemotherapy
Where
Atlanta, Baltimore, Boston, Chicago, Columbus, Dallas, Duarte, Houston, Jacksonville, Knoxville, Nashville, New York, Pittsburgh, Rochester, Salt Lake City, San Francisco, Santa Monica, Scottsdale, Seattle, St Louis
Age
18 years and over
People
390 worldwide
Run by
Boehringer Ingelheim
See details and how to joinNCT07544654 · EU 2025-523869-22-00
No phaseTaking people
Natural History of Familial Carcinoid Tumor
Where
Bethesda
Age
18 years to 100 years
People
1,600
Run by
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
See details and how to joinNCT00646022
No phaseEnrolling by invitation
Follow Up Protocol for Subjects Previously Enrolled on NCI Surgery Branch Studies
Where
Bethesda
Age
18 years and over
People
1,150
Run by
National Cancer Institute (NCI)
See details and how to joinNCT00923026
Phase 2Taking people
Immunotherapy Using Tumor Infiltrating Lymphocytes for Patients With Metastatic Cancer
Where
Bethesda
Age
18 years to 72 years
People
332
Run by
National Cancer Institute (NCI)
See details and how to joinNCT01174121
Phase 1Taking people
A First-in-Human Phase I Trial With Antibody Drug Conjugate ADCT-701 in Neuroendocrine Tumors, Carcinomas and Malignant Peripheral Nerve Sheath Tumors
Where
Bethesda
Age
18 years to 120 years
People
70
Run by
National Cancer Institute (NCI)
See details and how to joinNCT06041516
Phase 2Taking people
Study of CTX-471 in Patients With Neural Cell Adhesion Molecule (NCAM) Positive Neuroendocrine Neoplasms
Where
Seattle, St Louis
Age
18 years and over
People
58
Run by
Compass Therapeutics
See details and how to joinNCT07684170
Phase 2/3Taking people
Evaluating the Addition of the Immunotherapy Drug Atezolizumab to Standard Chemotherapy Treatment for Advanced or Metastatic Neuroendocrine Carcinomas That Originate Outside the Lung
Where
‘Aiea, Ames, Anaconda, Anaheim, Anchorage, Ankeny, Ann Arbor, Auburn, Aurora, Baldwin Park, Baton Rouge, Battle Creek, Bellflower, Bend, Berkeley, Billings, Boone, Bridgeport, Brighton, Brownstown, Buffalo, Burlington, Burnsville, Cameron Park, Canton, Cape Girardeau, Carmichael, Carroll, Cary, Centralia, Chambersburg, Charleston, Charlotte, Chelsea, Chicago, Clackamas, Clinton, Clinton Township, Clive, Coeur d'Alene, Columbus, Concord, Creston, Crown Point, Dallas, Danville, Dearborn, Decatur, DeKalb, Denver, Derby, Des Moines, Detroit, Duluth, Durham, East China Township, Eau Claire, Edina, Effingham, Elk Grove, Ephrata, ‘Ewa Beach, Fairfield, Farmington Hills, Flint, Fontana, Fort Dodge, Fort Lauderdale, Fort Worth, Fremont, Gastonia, Geneva, Gettysburg, Glastonbury, Glenview, Goldsboro, Grand Rapids, Grayslake, Great Falls, Greenwich, Grosse Pointe Woods, Guilford, Hanover, Harbor City, Hartford, Harvey, Honolulu, Houston, Irvine, Jackson, Jacksonville, Jefferson, Joplin, Kalamazoo, Kalispell, La Crosse, Lake Forest, Lansing, Lawton, Lebanon, Littleton, Livonia, Los Angeles, Macomb, Marshalltown, Marshfield, Mattoon, Metairie, Milwaukee, Minneapolis, Minocqua, Missoula, Modesto, Morgantown, Mountain View, Mount Vernon, Muskegon, Nampa, Nashville, Newberg, New Haven, New Lenox, New Orleans, New York, Niles, Normal, North Haven, Norton Shores, Novi, O'Fallon, Oklahoma City, Ontario, Oregon City, Orland Park, Palo Alto, Panorama City, Parker, Peabody, Phoenix, Pinehurst, Pontiac, Portland, Post Falls, Raleigh, Rapid City, Reed City, Rice Lake, Richardson, Riverside, Rochester, Rockford, Rock Hill, Rocklin, Roseville, Royal Oak, Sacramento, Saint Johnsbury, Saint Joseph, Saint Louis Park, Saint Paul, Salt Lake City, San Diego, Sandpoint, San Francisco, San Marcos, Santa Cruz, Santa Rosa, Seattle, Shakopee, Shelby, Springfield, Stamford, Stevens Point, St Louis, Stony Brook, Sunnyvale, Tampa, Toledo, Torrington, Traverse City, Troy, Trumbull, Urbana, Vallejo, Warren, Warrenville, Waterbury, Waterford, Waukee, West Bloomfield, West Des Moines, Westerly, Weston, Woodland, Woodland Hills, Wyandotte, Wyoming, York, Yorkville, Ypsilanti
Age
18 years and over
People
189
Run by
National Cancer Institute (NCI)
See details and how to joinNCT05058651
Phase 2Taking people
At-Home Cancer Directed Therapy Versus in Clinic for the Treatment of Patients With Advanced Cancer
Where
Grand Forks, Jacksonville
Age
18 years and over
People
220
Run by
Mayo Clinic
See details and how to joinNCT05969860
Phase 3Taking people
Somatostatin Analogues vs. Observation After Peptide Receptor Radionuclide Therapy (PRRT) in Nonfunctional Neuroendocrine Neoplasms
Where
San Francisco, St Louis
Age
18 years and over
People
240
Run by
Washington University School of Medicine
See details and how to joinNCT07842172
Phase 2Taking people
Testing Lutetium Lu 177 Dotatate in Patients With Somatostatin Receptor Positive Advanced Bronchial Neuroendocrine Tumors
Where
Ankeny, Aventura, Beverly Hills, Birmingham, Boston, Chicago, Cleveland, Columbus, Coral Gables, Deerfield Beach, Des Moines, Durham, Loma Linda, Los Angeles, Miami, Nashville, New Lenox, Orland Park, Philadelphia, Pittsburgh, Plantation, Rochester, Salt Lake City, San Francisco, St Louis, Torrance, Washington D.C.
Age
18 years and over
People
70
Run by
National Cancer Institute (NCI)
See details and how to joinNCT04665739
Phase 2Taking people
Enasidenib in IDH2-Mutated Malignant Sinonasal and Skull Base Tumors
Where
Bethesda
Age
18 years to 120 years
People
40
Run by
National Cancer Institute (NCI)
See details and how to joinNCT06176989
Phase 2Taking people
Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors
Where
Aberdeen, Aitkin, Alcoa, Allentown, Alton, Ames, Anaconda, Anchorage, Ankeny, Ann Arbor, Arroyo Grande, Ashland, Atlanta, Aurora, Aventura, Baker City, Ballwin, Baltimore, Bardstown, Basking Ridge, Baton Rouge, Beavercreek, Bellevue, Bellingham, Belpre, Bend, Bethesda, Bethlehem, Bettendorf, Billings, Birmingham, Bloomington, Boardman, Boise, Bolivar, Bonne Terre, Boone, Bozeman, Brainerd, Branson, Brighton, Brooklyn, Brownstown, Bryan, Buffalo, Burbank, Burien, Burlington, Burnsville, Burr Ridge, Caldwell, Cambridge, Canton, Cape Girardeau, Carbondale, Caro, Carson City, Carterville, Carthage, Centerville, Centralia, Chanute, Chapel Hill, Charleston, Chelsea, Chicago, Chillicothe, Cincinnati, City of Saint Peters, Clackamas, Clarkston, Clinton Township, Clive, Clovis, Cody, Coeur d'Alene, Colorado Springs, Columbus, Commack, Coon Rapids, Coos Bay, Corbin, Council Bluffs, Covington, Creston, Creve Coeur, Cudahy, Dallas, Danville, Dayton, Dearborn, Decatur, Deer River, Delaware, Denver, Des Moines, Detroit, Detroit Lakes, Dixon, Dodge City, Dublin, Duluth, Durango, East China Township, East Stroudsburg, Eau Claire, Edina, Edmonds, Effingham, El Dorado, Emeryville, Emmett, Enumclaw, Erie, Eureka, Everett, Fairway, Fargo, Farmington, Federal Way, Fergus Falls, Findlay, Flint, Fort Dodge, Fort Lauderdale, Fort Smith, Fort Worth, Fosston, Franklin, Frederick, Fridley, Fruitland, Gahanna, Galesburg, Garden City, Germantown, Grafton, Grand Island, Great Bend, Great Falls, Green Bay, Greenbrae, Greensburg, Greenville, Grosse Pointe Woods, Grove City, Harrison, Hays, Hazleton, Helena, Henderson, Hendersonville, Hibbing, Homer Glen, Hot Springs, Independence, Iowa City, Issaquah, Jackson, Jamestown, Jefferson, Jefferson City, Jefferson Hills, Johns Creek, Joplin, Kalispell, Kansas City, Kearney, Kenner, Kennewick, Kenosha, Kettering, Kewanee, Kingman, Knoxville, Lacey, Lake Forest, Lake Success, Lakewood, Lancaster, Lansing, Las Vegas, Lawrence, Lawton, Lee's Summit, Lexington, Liberal, Lima, Lincoln, Littleton, Livonia, London, Longmont, Longview, Los Angeles, Louisville, Macomb, Manhattan, Mansfield, Maple Grove, Maplewood, Marietta, Marinette, Marion, Marlette, Marshalltown, Marshfield, Martinez, Marysville, Mattoon, Maywood, McPherson, Melrose Park, Meridian, Metairie, Miami Beach, Middletown, Milwaukee, Mineola, Minneapolis, Minocqua, Missoula, Monroeville, Monticello, Montvale, Mount Vernon, Mukwonago, Nampa, Nashville, Natrona Heights, Newark, Newberg, New Lenox, New Orleans, Newport Beach, New Richmond, Newton, New Ulm, New York, N. Huntingdon, Novi, Oakland, Oak Park, Oconomowoc, O'Fallon, Oklahoma City, Olathe, Omaha, Ontario, Oregon City, Orlando, Orland Park, Oshkosh, Ottawa, Pahrump, Papillion, Parker, Park Rapids, Parsons, Peabody, Pekin, Peoria, Perrysburg, Peru, Phoenix, Pittsburg, Pittsburgh, Pontiac, Port Huron, Portland, Portsmouth, Post Falls, Poulsbo, Pratt, Princeton, Pueblo, Racine, Redmond, Reno, Renton, Rice Lake, Richardson, Richmond, Robbinsdale, Rochester, Rochester Hills, Rolla, Saginaw, Sainte Genevieve, Saint Joseph, Saint Louis Park, Saint Paul, Salina, Sandpoint, Sandstone, San Luis Obispo, Santa Maria, Scottsdale, Seattle, Sedro-Woolley, Shakopee, Sheboygan, Shelby, Shelton, Shepherdsville, Sheridan, Shiloh, Silverdale, Springfield, Sterling Heights, Stevens Point, Stillwater, St Louis, Sullivan, Summit, Swansea, Syracuse, Tacoma, Tawas City, Toledo, Topeka, Troy, Tucson, Tulsa, Twin Falls, Two Rivers, Uniondale, Urbana, Vancouver, Virginia, Waconia, Walla Walla, Walnut Creek, Warren, Washington, Washington D.C., Waukee, Waukesha, Wauwatosa, Wellington, West Allis, West Bloomfield, West Branch, West Chester, West Des Moines, Westerville, Weston, Westwood, Wexford, Wichita, Willmar, Winchester, Winfield, Woodbury, Wyandotte, Wyoming, Yakima, Yelm, Yorkville, Youngstown, Ypsilanti, Zanesville
Age
18 years and over
People
314 worldwide
Run by
National Cancer Institute (NCI)
See details and how to joinNCT03866382
Phase 1Not yet taking people in United States
A Study of 177Lu-DTPA-SC16.56 in People With Neuroendocrine Carcinomas of the Lung and Prostate
Where
Basking Ridge, Commack, Harrison, Middletown, Montvale, New York, Rockville Centre
Age
18 years and over
People
12
Run by
Memorial Sloan Kettering Cancer Center
See details and how to joinNCT06941480
Phase 2Taking people
Testing the Safety and Effectiveness of Radiation-based Treatment (Lutetium Lu 177 Dotatate) for Metastatic Prostate Cancer That Has Neuroendocrine Cells
Where
Baltimore, Chicago, Columbus, Dallas, Duarte, Houston, Lexington, Los Angeles, Madison, Sacramento, Winston-Salem
Age
18 years and over
People
35
Run by
National Cancer Institute (NCI)
See details and how to joinNCT05691465
Phase 2Taking people
Comparing Retreatment of 177Lu-DOTATATE PRRT Versus the Usual Treatment in Patients With Metastatic Unresectable Gastroenteropancreatic Neuroendocrine Tumors, NET RETREAT Trial
Where
Albuquerque, Ankeny, Aurora, Aventura, Birmingham, Chicago, Clive, Columbus, Coral Gables, Crown Point, Deerfield Beach, DeKalb, Des Moines, Detroit, Geneva, Jacksonville, Lexington, Miami, New Lenox, North Miami, Oak Brook, Orland Park, Phoenix, Plantation, Rochester, Salt Lake City, San Francisco, Tucson, Warrenville, Waukee
Age
18 years and over
People
100 worldwide
Run by
National Cancer Institute (NCI)
See details and how to joinNCT05773274
Phase 1Taking people
Study of RYZ401 in Subjects With Solid Tumors Expressing SSTRs.
Where
Charlottesville, Columbus, Iowa City, Jacksonville, Lexington, Los Angeles, Nashville, Phoenix, Portland, Rochester, Salt Lake City, St Louis
Age
18 years and over
People
104 worldwide
Run by
RayzeBio, Inc.
See details and how to joinNCT07165132
No phaseTaking people
Tissue Procurement and Natural History Study of Neuroendocrine Neoplasms (NENs) Including Adrenocortical Carcinoma (ACC)
Where
Bethesda
Age
18 years to 120 years
People
300
Run by
National Cancer Institute (NCI)
See details and how to joinNCT05237934
Phase 2Taking people
Administration of Autologous T-Cells Genetically Engineered to Express T-Cell Receptors Reactive Against Neoantigens in People With Metastatic Cancer
Where
Bethesda
Age
18 years to 72 years
People
285
Run by
National Cancer Institute (NCI)
See details and how to joinNCT03412877
Phase 2/3Taking people
Zanzalintinib Versus Everolimus in Participants With Locally Advanced or Metastatic Neuroendocrine Tumors
Where
Albuquerque, Bethesda, Beverly Hills, Birmingham, Boston, Buffalo, Chapel Hill, Charlottesville, Cleveland, Columbus, Dallas, Detroit, Durham, Fairfax, Fargo, Grand Rapids, Jacksonville, Knoxville, Lexington, Los Angeles, Metairie, Milwaukee, Nashville, New York, Omaha, Orlando, Palo Alto, Philadelphia, Phoenix, Pittsburgh, Portland, Rochester, Salt Lake City, Santa Monica, Seattle, St Louis, Tampa, Tucson, Vallejo, Washington D.C.
Age
18 years and over
People
440 worldwide
Run by
Exelixis
See details and how to joinNCT06943755 · EU 2025-521043-20-00
Phase 1Taking people
Evaluating BL-M14D1 in Subjects With Locally Advanced or Metastatic Small Cell Lung Cancer and Neuroendocrine Tumors
Where
Atlanta, Aurora, Columbus, Dallas, East Brunswick, Fairfax, Glendale, Greenville, Hackensack, Houston, Huntsville, Long Beach, Los Angeles, New Brunswick, New Haven, New Orleans, New York, Portland, San Antonio, San Francisco, Seattle
Age
18 years and over
People
120 worldwide
Run by
SystImmune Inc.
See details and how to joinNCT07080242
Phase 1Taking people
Pilot Study for Detection of PSMA-Low CRPC-NE Tumors With Fluciclovine PET/CT
Where
Boston
Age
18 years and over
People
30
Run by
Brigham and Women's Hospital
See details and how to joinNCT06062745
Phase 2Taking people
18F-Fibroblast Activation Protein Inhibitor ([18F]FAPI-74) PET Imaging for Cancer Detection
Where
Bethesda
Age
18 years to 120 years
People
320
Run by
National Cancer Institute (NCI)
See details and how to joinNCT06503146
Phase 1Taking people
Autologous B7-H3 Chimeric Antigen Receptor T Cells in Previously Treated Extensive-Stage Small Cell Lung Cancer With Recurrent or Refractory Disease
Where
Bethesda
Age
18 years to 120 years
People
40
Run by
National Cancer Institute (NCI)
See details and how to joinNCT07509034