Neuromyelitis optica (NMOSD) trials in China

In China 30 Also abroad 60

30 trials · From ClinicalTrials.gov, checked 11 November 2026. Ask the study team whether a trial fits you.

No phaseTaking people
Registry of Patients With AQP4+ NMOSD Treated With Alexion C5 Inhibitor Therapies
Where
Beijing, Guangzhou, Henan, Shanghai, Sichuan, Wuhan
Age
18 years and over
People
200 worldwide
Run by
Alexion Pharmaceuticals, Inc.
See details and how to joinNCT05966467
Phase 3Taking people
A Study to Evaluate Pharmacokinetics, Efficacy, Safety, Tolerability, and Pharmacodynamics of Satralizumab in Pediatric Patients With Aquaporin-4 Antibody Positive Neuromyelitis Optica Spectrum Disorder (NMOSD)
Where
Guangzhou, Shanghai
Age
2 years to 11 years
People
8 worldwide
Run by
Hoffmann-La Roche
See details and how to joinNCT05199688 · EU 2023-507817-85-00
Phase 1Taking people
The Safety and Efficacy of NouvSoma001 in Neuromyelitis Optica Spectrum Disorders
Where
Wuhan
Age
18 years to 65 years
People
69
Run by
Tongji Hospital
See details and how to joinNCT06620809
No phaseTaking people
HANDLE-a Real World Study on Satralizumab in NMOSD
Where
Shanghai
Age
12 years and over
People
100
Run by
Huashan Hospital
See details and how to joinNCT06829524
Phase 3Taking people
Efficacy, Safety, Pharmacokinetics, Pharmacodynamics, and Immunogenicity Study of Ravulizumab in Chinese Adults With Neuromyelitis Optica Spectrum Disorder (NMOSD)
Where
Beijing, Chengdu, Dongguan, Jinan, Shanghai, Shijiazhuang, Taiyuan, Wenzhou, Wuhan
Age
18 years to 130 years
People
19
Run by
Alexion Pharmaceuticals, Inc.
See details and how to joinNCT07557420
Phase 2Not yet taking people in China
Efficacy and Safety of Low-Dose IL-2 in Neuromyelitis Optica Spectrum Disorder
Where
Beijing
Age
18 years to 74 years
People
60
Run by
Peking University People's Hospital
See details and how to joinNCT07809724
No phaseTaking people
A Multicenter Prospective Real-World Effectiveness and Safety of Satralizumab in the Early Treatment of Attacks in NMOSD
Where
Beijing
Age
18 years and over
People
50
Run by
Junwei Hao, MD
See details and how to joinNCT07762872
No phaseTaking people
Biomarkers in Autoimmune Disease of Nervous System
Where
Wuhan
Age
18 years and over
People
50,000
Run by
Tongji Hospital
See details and how to joinNCT06502015
Phase 4Not yet taking people in China
Crisugabalin in NMOSD Neuropathic Pain: A Randomized, Double-Blind, Placebo-Controlled Exploratory Trial
Where
Beijing, Changchun, Chongqing, Harbin, Hohhot, Kunming, Shenyang, Ürümqi, Xi'an
Age
18 years to 75 years
People
110
Run by
Tang-Du Hospital
See details and how to joinNCT07699770
Phase 1Not yet taking people in China
A Study of C-CAR168 in the Treatment of Autoimmune Diseases Refractory to Standard Therapy
Where
Qingdao
Age
18 years to 70 years
People
18
Run by
The Affiliated Hospital of Qingdao University
See details and how to joinNCT07676266
No phaseTaking people
Cohort Study on Neuroimmune Diseases in the Reproductive Age
Where
Guangzhou
Age
20 years to 55 years
People
100
Run by
Third Affiliated Hospital, Sun Yat-Sen University
See details and how to joinNCT07653984
Early phase 1Not yet taking people in China
The Safety and Efficacy of KSVCBD Injection in Neuromyelitis Optica Spectrum Disorder.
Where
Beijing
Age
18 years to 65 years
People
18
Run by
Chinese PLA General Hospital
See details and how to joinNCT07592754
Phase 3Taking people
Modified Zipper Therapy for AQP4-IgG Positive Neuromyelitis Optica Spectrum Disorder
Where
Tianjin
Age
18 years to 80 years
People
198
Run by
Tianjin Medical University General Hospital
See details and how to joinNCT07420296
Phase 1Taking people
Safety and Pharmacodynamics of QH103 Cell Injection in the Treatment of Patients With Relapsed/Refractory Antibody-Mediated Neurological Autoimmune Diseases.
Where
Wuhan
Age
18 years to 75 years
People
6
Run by
Tongji Hospital
See details and how to joinNCT07526493
Phase 2/3Taking people
A Clinical Study of B001 Injection in the Treatment of Neuromyelitis Optica Spectrum Disorders(NMOSD)
Where
Beijing, Cangzhou, Changsha, Chengdu, Fuzhou, Guangzhou, Guiyang, Hangzhou, Harbin, Hefei, Huizhou, Jinan, Jining, Kunming, Nanchang, Nanyang, Qingdao, Shenyang, Shenzhen, Shijiazhuang, Shiyan, Taiyuan, Tianjin, Wenzhou, Wuhan, Xiamen, Xi'an, Xianyang, Yantai, Yongzhou, Zaozhuang, Zhengzhou, Zigong
Age
18 years and over
People
132
Run by
Shanghai Jiaolian Drug Research and Development Co., Ltd
See details and how to joinNCT06413654
Phase 4Taking people
Therapy in the Acute Phase of NMOSD: A Multicenter Prospective Real-World Study
Where
Beijing
Age
18 years to 65 years
People
200
Run by
Chinese PLA General Hospital
See details and how to joinNCT07410039
Early phase 1Not yet taking people in China
Universal Chimeric Antigen Receptor T-Cell （UCAR T-cell） Therapy Targeting CD19/ BCMA（QT-019C） in Patients With r/ r Neurological Autoimmune Diseases
Where
Tianjin
Age
18 years and over
People
15
Run by
Tianjin Huanhu Hospital
See details and how to joinNCT07392528
Phase 1/2Taking people
Ofatumumab in AQP4-IgG Seropositive NMOSD
Where
Xi'an
Age
18 years and over
People
5
Run by
Tang-Du Hospital
See details and how to joinNCT05504694
No phaseTaking people
Efficacy and Safety of Transcranial Temporal Interference Stimulation (tTIS) for Neuropathic Pain in Neuromyelitis Optica Spectrum Disorder (NMOSD)
Where
Xi'an
Age
18 years to 75 years
People
12
Run by
Tang-Du Hospital
See details and how to joinNCT07377305
No phaseEnrolling by invitation
Normal Chinese Lifespan Brain Charts Initiative (NCLBCI)
Where
Beijing
Age
6 years to 90 years
People
10,000
Run by
Beijing Tiantan Hospital
See details and how to joinNCT06643858
No phaseNot yet taking people in China
Prospective Cohort Study of Neuromyelitis Optica Spectrum Disorders (NMOSD)
Where
Xiamen
Age
18 years and over
People
4,000
Run by
Xiamen Hospital of Traditional Chinese Medicine
See details and how to joinNCT07266051
Early phase 1Taking people
Universal Chimeric Antigen Receptor T-Cell （UCAR T-cell） Therapy Targeting CD19/B Cell Maturation Antigen （CD19/BCMA） in Patients With r/r Neurological Autoimmune Diseases
Where
Tianjin
Age
18 years and over
People
12
Run by
Tianjin Huanhu Hospital
See details and how to joinNCT06939166
No phaseTaking people
Monoclonal Antibody-Based Therapies for AQP4-Positive NMOSD
Where
Wuhan
Age
18 years to 65 years
People
200
Run by
Tongji Hospital
See details and how to joinNCT06885957
Phase 1Taking people
A Study of C-CAR168 in the Treatment of Autoimmune Diseases Refractory to Standard Therapy
Where
Shanghai
Age
18 years to 70 years
People
30
Run by
RenJi Hospital
See details and how to joinNCT06249438
No phaseTaking people
Protein A immuNoaDsorption for the Treatment of Acute Episodes of Neuromyelitis Optica Spectrum Disorder
Where
Guangzhou
Age
18 years to 65 years
People
144
Run by
Third Affiliated Hospital, Sun Yat-Sen University
See details and how to joinNCT06763848