Obesity trials in United States

In United States 744 Also abroad 1939

744 trials · From ClinicalTrials.gov, checked 12 November 2026. Ask the study team whether a trial fits you.

No phaseTaking people
Youth-Onset Type 2 Diabetes and Heart Disease: The Young at Heart Prospective Cohort Study
Where
Bethesda, Washington D.C.
Age
12 years to 25 years
People
930
Run by
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
See details and how to joinNCT06730113
No phaseTaking people
Pennington Generation Cohort
Where
Baton Rouge
People
3,000
Run by
Pennington Biomedical Research Center
See details and how to joinNCT06849206
No phaseTaking people
Plant-Based Online Weight Loss Through Education and Resources Program and Study
Where
Washington D.C.
Age
18 years and over
People
100
Run by
Physicians Committee for Responsible Medicine
See details and how to joinNCT07095543
Phase 3Taking people
A Study of Once-daily Oral ASC30 to Evaluate the Efficacy and Safety in Adult Participants With Obesity or Overweight With Type 2 Diabetes
Where
Austin, Banning, Baton Rouge, Birmingham, Bluffton, Boca Raton, Boise, Bowie, Brownsville, Canton, Charlotte, Chula Vista, Cincinnati, Clemson, Cleveland, Columbia, Columbus, Covina, Dayton, Daytona Beach, Decatur, DeSoto, Durham, East Northport, East Syracuse, Eugene, Evansville, Frisco, Gaffney, Gardena, Greenville, Gulfport, Hampton, Houston, Huntsville, Indianapolis, Jackson, Jacksonville, Jersey City, Kansas City, La Mesa, Las Vegas, Leesburg, Little Rock, Los Angeles, Mankato, Melbourne, Memphis, Mesquite, Metairie, Morehead City, New Windsor, Oklahoma City, Olive Branch, Peoria, Philadelphia, Phoenix, Pittsburgh, Raleigh, Rockville, Sacramento, Salt Lake City, San Antonio, Schaumburg, Seattle, Southfield, South Miami, St Louis, Sugar Land, Tampa, Tarzana, The Villages, Tomball, Tucson, Tustin, Union City, Valparaiso, Washington D.C., Waxahachie, Weslaco, Wichita Falls, Winter Park
Age
18 years and over
People
1,560 worldwide
Run by
Ascletis Pharma (China) Co., Limited
See details and how to joinNCT07743450
Phase 3Taking people
A Study of Once-daily Oral ASC30 to Evaluate the Efficacy and Safety in Adult Participants With Obesity or Overweight With Weight-Related Comorbidities
Where
Austin, Banning, Baton Rouge, Birmingham, Bluffton, Boca Raton, Boise, Bowie, Brownsville, Canton, Charlotte, Chula Vista, Cincinnati, Clemson, Cleveland, Columbia, Columbus, Covina, Dayton, Daytona Beach, Decatur, DeSoto, Eugene, Evansville, Frisco, Gaffney, Gardena, Greenville, Gulfport, Hampton, Huntsville, Indianapolis, Jackson, Jacksonville, Kansas City, La Mesa, Las Vegas, Leesburg, Little Rock, Los Angeles, Melbourne, Memphis, Mesquite, Morehead City, New Windsor, Olive Branch, Philadelphia, Phoenix, Raleigh, Rockville, Salt Lake City, San Antonio, Schaumburg, South Miami, St Louis, Sugar Land, Tampa, Tarzana, The Villages, Tomball, Tucson, Tustin, Union City, Valparaiso, Washington D.C., Weslaco, Wichita Falls, Winter Park
Age
18 years and over
People
3,003 worldwide
Run by
Ascletis Pharma (China) Co., Limited
See details and how to joinNCT07743463
No phaseNot yet taking people in United States
Continuous Glucose Monitoring in Metabolic Surgery
Where
Baton Rouge
Age
20 years to 60 years
People
20
Run by
Pennington Biomedical Research Center
See details and how to joinNCT07095972
No phaseTaking people
Feasibility and Acceptability of a Pediatric Referral to Summer Day Camps to Treat Obesity in Children From Low-Income Households
Where
Orlando
Age
5 years to 11 years
People
80
Run by
University of Central Florida
See details and how to joinNCT07464015
Phase 1/2Taking people
First-in-human Study of the Safety, Tolerability, Pharmacokinetics, and Food Effect of ACCG-2671
Where
Cypress, Decatur, Dilworth, Lake Forest, Springfield, Webster
Age
25 years to 75 years
People
164
Run by
Aconcagua Bio, Inc. a wholly owned subsidiary of Structure Therapeutics
See details and how to joinNCT07815678
No phaseTaking people
Exercise Response in Humans With Obesity
Where
Rochester
Age
20 years to 45 years
People
120
Run by
Mayo Clinic
See details and how to joinNCT05857150
Phase 3Taking people
AMAZE 3: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Obstructive Sleep Apnoea Not Treated With Positive Airway Pressure Lose Weight and Improve Sleep Apnoea
Where
Atlanta, Chicago, Cincinnati, DeSoto, DuBois, El Paso, Houston, Lawrenceville, Miami, Naples, New York, Ocala, Renton, San Antonio, San Diego, Sugar Land
Age
18 years and over
People
300 worldwide
Run by
Novo Nordisk A/S
See details and how to joinNCT07571005 · EU 2024-520442-36-00
Phase 4Taking people
The Effects of Lumateperone on Obesity and Physiologic Aging and Their Association With Antidepressant Response in Bipolar Depression
Where
Boston
Age
18 years to 65 years
People
25
Run by
Massachusetts General Hospital
See details and how to joinNCT07699445
No phaseEnrolling by invitation
Genetics of Obesity, Diabetes, and Heart Disease in African Diaspora Populations
Where
Bethesda
Age
18 years to 120 years
People
1,100
Run by
National Human Genome Research Institute (NHGRI)
See details and how to joinNCT01316783
No phaseTaking people
Cottonseed Oil Versus Matched PUFA Effects
Where
Athens
Age
25 years to 75 years
People
90
Run by
University of Georgia
See details and how to joinNCT06382298
No phaseTaking people
How a Single Workout Affects Gut Bugs in Women With Different Fitness Levels and Body Types
Where
Washington D.C.
Age
21 years to 40 years
People
40
Run by
George Washington University
See details and how to joinNCT06691100
Phase 2Taking people
Efficacy and Safety of Tirzepatide Versus Placebo or Lisdexamfetamine Dimesylate for Binge-Eating Disorder
Where
Baltimore
Age
18 years and over
People
105
Run by
Johns Hopkins University
See details and how to joinNCT06847399
Phase 1Not yet taking people in United States
Development of a MHBC Intervention for Weight Loss and Smoking Cessation for Pre-Bariatric Surgery Patients
Where
Charleston
Age
18 years to 65 years
People
20
Run by
Medical University of South Carolina
See details and how to joinNCT07224087
No phaseTaking people
Intermittent Cottonseed Oil Consumption
Where
Athens
Age
25 years to 75 years
People
75
Run by
University of Georgia
See details and how to joinNCT07246408
Phase 1Taking people
A Research Study Investigating How a New Medicine NNC0113-5840 Works in People With Overweight or Obesity
Where
Baltimore, Glendale
Age
18 years to 55 years
People
48
Run by
Novo Nordisk A/S
See details and how to joinNCT07566390
Phase 3Taking people
Research Study on How Well Oral Semaglutide Works for Weight Loss in Adults With Excess Body Weight
Where
Birmingham, City of Saint Peters, Corvallis, Dallas, Delray Beach, Escondido, Fort Myers, Honolulu, Huntington Park, Las Vegas, Los Angeles, Louisville, Philadelphia, Spartanburg, Tampa, Winchester
Age
18 years and over
People
450 worldwide
Run by
Novo Nordisk A/S
See details and how to joinNCT07770841 · EU 2025-524626-18-00
No phaseTaking people
Inflammation, Diabetes, Ethnicity and Obesity Cohort
Where
San Francisco
Age
18 years to 75 years
People
350
Run by
University of California, San Francisco
See details and how to joinNCT03022682
Early phase 1Taking people
Effect of Tirzepatide on Markers of MASLD in Patients With Obesity
Where
Albuquerque
Age
18 years to 75 years
People
8
Run by
University of New Mexico
See details and how to joinNCT06934642
Phase 3Taking people
A Research Study to Compare Two Different Versions of Injectable Cagrilintide and Placebo in People With Excess Body Weight
Where
Conyers, Greensboro, Honolulu, Indianapolis, Lexington, Newport News, North Charleston, Oak Park, Richmond, Wilmington, Winchester
Age
18 years and over
People
285 worldwide
Run by
Novo Nordisk A/S
See details and how to joinNCT07745504 · EU 2025-524249-29-00
Phase 1Taking people
A First-in-human Research Study on How NNC0721-8060 Works in People Living With Overweight or Obesity
Where
Lenexa, San Antonio
Age
18 years to 55 years
People
142
Run by
Novo Nordisk A/S
See details and how to joinNCT07767175
No phaseNot yet taking people in United States
Network-Based Support to Help Community Coalition Members Choose and Use Strategies to Improve Child Health
Where
Pittsburgh
Age
18 years and over
People
3,300
Run by
University of Pittsburgh
See details and how to joinNCT07804550
No phaseTaking people
This Study Will Evaluate Cardiorespiratory and Muscular Fitness to Examine Associations With Anthropometric Characteristics and Other Indicators of Cardiometabolic Risk Among Patients With or Without Autism Spectrum Disorder
Where
Charlottesville
Age
6 years to 18 years
People
200
Run by
University of Virginia
See details and how to joinNCT07804680