Obesity trials in United States

In United States 744 Also abroad 1939

744 trials · From ClinicalTrials.gov, checked 12 November 2026. Ask the study team whether a trial fits you.

Early phase 1Taking people
Pre-Surgical Tirzepatide-Assisted Weight Loss in Overweight and Obese Men With Intermediate Risk Prostate Cancer: A Pilot Feasibility Study
Where
Houston
Age
18 years and over
People
30
Run by
M.D. Anderson Cancer Center
See details and how to joinNCT06759701
No phaseNot yet taking people in United States
Evaluating Care Integration Between Pediatric Primary Care Providers and WIC Nutritionists
Where
University Park
Age
18 years to 40 years
People
380
Run by
Penn State University
See details and how to joinNCT07494097
Phase 1Taking people
Safety and Drug Concentrations of REGN20934 in Adults With Overweight or Obesity
Where
Glendale
Age
18 years to 65 years
People
90
Run by
Regeneron Pharmaceuticals
See details and how to joinNCT07594093
Phase 1Taking people
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ASC35 Injection in Participants With Obesity or Overweight
Where
Baltimore
Age
18 years to 65 years
People
84
Run by
Ascletis Pharma (China) Co., Limited
See details and how to joinNCT07842640
Phase 3Taking people
A Study of Tirzepatide in Adolescents With Obesity and Weight-Related Comorbidities (SURMOUNT-ADOLESCENTS-2)
Where
Ammon, Buffalo, Chicago, Corpus Christi, DeSoto, Fort Worth, Indianapolis, Layton, Los Angeles, Sacramento, Shavano Park, Syracuse, Weslaco, Wilmington
Age
12 years to 17 years
People
300 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT06439277
Early phase 1Taking people
Cardiovascular Effects of Angiotensin-(1-7) in Obesity Hypertension
Where
Hershey
Age
18 years to 65 years
People
52
Run by
Milton S. Hershey Medical Center
See details and how to joinNCT06482853
No phaseTaking people
Effect of Prenatal and Postnatal Intervention Strategies on Breastfeeding Outcomes in Women With Excessive Weight (Ready, Set, Nourish Study)
Where
Little Rock
Age
18 years and over
People
240
Run by
Arkansas Children's Hospital Research Institute
See details and how to joinNCT06929091
Phase 3Taking people
AMAZE 1: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight Lose Weight
Where
Amarillo, Arlington, Chapel Hill, Charleston, City of Saint Peters, Conyers, Cumberland, Dallas, Forney, Greensboro, Indianapolis, Miramar, Newport News, New York, North Charleston, Orlando, Philadelphia, Renton, Simpsonville, Skokie, Wilmington, Winchester
Age
18 years and over
People
1,150 worldwide
Run by
Novo Nordisk A/S
See details and how to joinNCT07339423 · EU 2024-520440-42-00
Phase 1Taking people
A Phase 1 Study of VK2735 in Obese Adults Without Comorbidities
Where
Lake Forest, Miami
Age
18 years to 60 years
People
270
Run by
Viking Therapeutics, Inc.
See details and how to joinNCT07838740
No phaseTaking people
Dietary Insights and Nutritional Education in Adults on GLP-1 Therapy
Where
Columbia
Age
18 years to 65 years
People
50
Run by
University of South Carolina
See details and how to joinNCT07518407
Phase 1Taking people
A Study to Learn How Different Amounts of the Study Medicine Called PF-08642534 Are Tolerated and Act in the Body of People Who Have Obesity
Where
Lake Forest
Age
18 years to 70 years
People
120
Run by
Pfizer
See details and how to joinNCT07731139
Phase 1Taking people
A Study of Tirzepatide (LY3298176) in Participants With Type 1 Diabetes Mellitus and Overweight or Obesity
Where
Miami
Age
18 years to 70 years
People
18
Run by
Eli Lilly and Company
See details and how to joinNCT07803744
Phase 4Taking people
Pioglitazone on Heart Failure in Type-2 Diabetes Mellitus Participants
Where
San Antonio
Age
30 years to 70 years
People
78
Run by
The University of Texas Health Science Center at San Antonio
See details and how to joinNCT05838287
No phaseTaking people
Nutrition Optimization and Community Upliftment for Postpartum Recovery
Where
Baltimore
Age
18 years and over
People
40
Run by
Johns Hopkins University
See details and how to joinNCT06445530
No phaseTaking people
CHOICE to AVOID or RESIST
Where
Beverly Hills
Age
18 years to 80 years
People
60
Run by
Cedars-Sinai Medical Center
See details and how to joinNCT06521021
No phaseTaking people
Impact of Lean Pork on Endothelial Function in Perimenopause
Where
Baton Rouge
Age
40 years to 55 years
People
30
Run by
Pennington Biomedical Research Center
See details and how to joinNCT06976112
Phase 3Taking people
A Study of Eloralintide (LY3841136) in Participants With Obesity, or Overweight Without Type 2 Diabetes
Where
Albuquerque, Atlantis, Baltimore, Bellaire, Dallas, Dunwoody, Escondido, Fountain Valley, Greenville, Honolulu, Hyattsville, Lake Charles, Las Vegas, Lawrenceville, Miami, Monroe, Mt. Dora, Mt. Pleasant, Nashville, Norfolk, Palm Springs, Pembroke Pines, Pensacola, Quincy, Rochester, Rolling Hills Estates, Sacramento, San Antonio, Santa Ana, Scottsdale, Stockbridge, St. Petersburg, Topeka, Troy, Tuscaloosa, Tustin, Uniontown, Warren Township, Waterbury, West Des Moines
Age
18 years and over
People
1,980 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT07321886 · EU 2025-523657-34-00
Phase 2Taking people
Semaglutide for Post-Smoking Cessation Weight Management
Where
Austin, Houston
Age
18 years to 75 years
People
197
Run by
The University of Texas Health Science Center, Houston
See details and how to joinNCT06173778
No phaseTaking people
Variability In Mixed Meal Tests: Fixed Versus Adjusted to Energy Needs Caloric Dose
Where
Phoenix
Age
18 years to 99 years
People
79
Run by
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
See details and how to joinNCT06223555
No phaseTaking people
The Dose Trial: Dose Intensity of Behavioral Interventions for Childhood Obesity
Where
Baton Rouge, Nashville
Age
5 years to 17 years
People
900
Run by
Vanderbilt University Medical Center
See details and how to joinNCT06654323
No phaseTaking people
Transition to Ambulatory Bariatric Surgery (TABS) Trial
Where
Nashville
Age
25 years to 55 years
People
200
Run by
Vanderbilt University Medical Center
See details and how to joinNCT07011628
No phaseNot yet taking people in United States
Phenolic Dependent And Independent Effects Of Whole Grain Sorghum On Immunometabolism
Where
Lincoln
Age
19 years to 64 years
People
30
Run by
University of Nebraska Lincoln
See details and how to joinNCT07832071
No phaseTaking people
Effect of Nicotinamide Riboside on Ketosis, Fat Oxidation & Metabolic Rate
Where
Bethesda
Age
18 years to 65 years
People
100
Run by
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
See details and how to joinNCT06044935
No phaseTaking people
Effects of Glucagon-like Peptide-1 (GLP-1) Agonist in Neuro-reproductive Function in Obese Adolescent Females With Polycystic Ovary Syndrome (PCOS)
Where
Jacksonville
Age
12 years to 18 years
People
20
Run by
Nemours Children's Clinic
See details and how to joinNCT07169136
No phaseNot yet taking people in United States
Modifying Diet to Improve Gut Microbiome
Where
Tampa
Age
18 years and over
People
28
Run by
H. Lee Moffitt Cancer Center and Research Institute
See details and how to joinNCT03924778