Prostate cancer trials in United States

In United States 655 Also abroad 1490

655 trials · From ClinicalTrials.gov, checked 15 November 2026. Ask the study team whether a trial fits you.

Phase 3Taking people
Comparing Two Different Boost Approaches in Radiation Therapy for People With Prostate Cancer
Where
Basking Ridge, Commack, Harrison, Middletown, Montvale, New York, Uniondale
People
224
Run by
Memorial Sloan Kettering Cancer Center
See details and how to joinNCT07548164
Phase 2Taking people
Study of PSMA-targeted Therapy and Androgen Receptor Suppression in Low-volume Metastatic ProstatE Cancer: SPARKLE Trial
Where
Rochester
Age
18 years and over
People
202
Run by
Mayo Clinic
See details and how to joinNCT07650240
Phase 2Taking people
Carboplatin or Olaparib for BRcA Deficient Prostate Cancer
Where
Ann Arbor, Aurora, Bay Pines, Boise, Chicago, Decatur, Durham, Kansas City, Madison, Minneapolis, New York, Orlando, Philadelphia, Portland, Seattle, The Bronx, Washington D.C., West Los Angeles
Age
18 years and over
People
100
Run by
VA Office of Research and Development
See details and how to joinNCT04038502
Phase 2Taking people
High Dose Testosterone for ATM, CDK12 or CHEK2 Altered Prostate Cancers
Where
Aurora, Charleston, Decatur, Durham, Gainesville, Houston, Kansas City, Louisville, Madison, Memphis, Nashville, Orlando, Portland, Salisbury, Seattle, St Louis, West Haven
Age
18 years and over
People
51
Run by
VA Office of Research and Development
See details and how to joinNCT05011383
No phaseTaking people
Two-fraction HDR Monotherapy for Localized Prostate Cancer
Where
San Francisco
Age
18 years and over
People
17
Run by
University of California, San Francisco
See details and how to joinNCT05665738
Phase 1Taking people
Phase 1 Trial to Study JANX013 and JANX007 Combination in mCRPC
Where
Nashville
Age
18 years and over
People
110
Run by
Janux Therapeutics
See details and how to joinNCT07813637
Phase 2Not yet taking people in United States
Phase II Trial of Zanzalitinib in Patients With Metastatic Castration Resistant Prostate Cancer
Where
Cleveland
Age
18 years and over
People
19
Run by
Pedro Barata, MD, MSc
See details and how to joinNCT07608718
Phase 1/2Taking people
TT-4 and TT-10 as Single Agents and in Combination in Subjects With Advanced Selected Solid Tumors and Pleural Mesothelioma
Where
Houston, Los Angeles
Age
18 years and over
People
35
Run by
Portage Biotech
See details and how to joinNCT04969315
No phaseTaking people
PROMISE Registry: A Prostate Cancer Registry of Outcomes and Germline Mutations for Improved Survival and Treatment Effectiveness
Where
Baltimore, New York, Seattle
Age
18 years and over
People
500
Run by
Prostate Cancer Clinical Trials Consortium
See details and how to joinNCT04995198
Phase 2Taking people
MDRT in Prostate Cancer Treated With Long-term Androgen Deprivation Therapy in the STAMPEDE Trial (METANOVA)
Where
Cleveland, Madison, New York
Age
18 years and over
People
200
Run by
Case Comprehensive Cancer Center
See details and how to joinNCT06150417
No phaseTaking people
Investigation of Impact of AI on Prostate Cancer Workflow
Where
Cleveland
Age
55 years to 80 years
People
150
Run by
Case Comprehensive Cancer Center
See details and how to joinNCT07084779
Phase 2Taking people
A Biomarker Study in Men With Localized Prostate Cancer Treated With Aglatimagene Besadenovec
Where
Lakewood, Las Vegas, Littleton, Myrtle Beach, Peoria, Saddle Brook, Towson
Age
18 years and over
People
45
Run by
Candel Therapeutics, Inc.
See details and how to joinNCT07332000
Phase 1Taking people
Trial of Xaluritamig in Adults With Metastatic Castration-resistant Prostate Cancer
Where
Cincinnati, Denver, Durham, Houston, Irving, Nashville, Norfolk, Philadelphia, Pittsburgh, Sioux Falls
Age
18 years and over
People
40 worldwide
Run by
Amgen
See details and how to joinNCT07493512
No phaseEnrolling by invitation
Development and Validation of a Non-Invasive AI Diagnostic Model for Prostate Cancer Using Multiparametric MRI and PSMA PET/CT
Where
Los Angeles
Age
18 years and over
People
1,500 worldwide
Run by
Xiangya Hospital of Central South University
See details and how to joinNCT07690306
Phase 2Taking people
The SUGAR Study; SBRT and Relugolix) for Prostate Cancer
Where
Lebanon, New Haven, New York, Seattle
Age
18 years and over
People
60
Run by
Yale University
See details and how to joinNCT06111781
No phaseTaking people
[18F]-Fluoro-2-Deoxy-D-Glucose and -[18F] Dihydro-Testosterone Pet Imaging in Patients With Progressive Prostate or Salivary Gland Cancer
Where
Basking Ridge, Commack, Harrison, Middletown, Montvale, New York, Uniondale
People
300
Run by
Memorial Sloan Kettering Cancer Center
See details and how to joinNCT00588185
Phase 3Taking people
Positron Emission Tomography Using 64Cu-SAR-bisPSMA in Participants With High-risk Prostate Cancer Prior to Radical Prostatectomy
Where
Albany, Austin, Birmingham, Dallas, Durham, Glenview, Grand Rapids, Indianapolis, Jacksonville, Little Rock, Los Angeles, Madison, Miami, Murray, Myrtle Beach, Nashville, New York, Omaha, Orange, Phoenix, Rochester, San Antonio, Springfield, Stanford, Tulsa, Wichita
Age
18 years and over
People
383 worldwide
Run by
Clarity Pharmaceuticals Ltd
See details and how to joinNCT06056830
No phaseTaking people
Feasibility and Effect of Wrapping Nerves With a Multi-Layer Perinatal Tissue Allograft During Prostatectomy
Where
Jacksonville
Age
45 years and over
People
45
Run by
Mayo Clinic
See details and how to joinNCT06940271
Phase 2Not yet taking people in United States
Prostate Specific Membrane Antigen (PSMA) Imaging for Detection of Residual and Metastatic Prostate Cancer
Where
St Louis
Age
18 years and over
People
20
Run by
Washington University School of Medicine
See details and how to joinNCT07593079
Phase 2Taking people
Pembrolizumab Plus 177Lu-PSMA-617 in Patients With Castration Resistant Prostate Cancer
Where
San Francisco
Age
18 years and over
People
48
Run by
University of California, San Francisco
See details and how to joinNCT05766371
No phaseTaking people
Debunking the Frailty-sarcopenIa-ADT Axis in mEtastatic Prostate canceR With multiComponent Exercise: The FIERCE Trial
Where
Boston
Age
18 years and over
People
80
Run by
Dana-Farber Cancer Institute
See details and how to joinNCT06040125
Phase 2Taking people
Sipuleucel-T Combined With Bipolar Androgen Therapy in Men With mCRPC
Where
New Haven
Age
18 years and over
People
26
Run by
Yale University
See details and how to joinNCT06100705
Phase 1/2Not yet taking people in United States
A Phase 1/2 Trial of ADI-212 in mCRPC
Where
Redwood City
Age
18 years and over
People
12
Run by
Adicet Therapeutics
See details and how to joinNCT07793435
No phaseTaking people
Daily Adaptive Radiation Therapy Using an Individualized Approach for Prostate Cancer
Where
Boston, Duarte, Irvine, Philadelphia, St Louis
Age
18 years and over
People
132 worldwide
Run by
Varian, a Siemens Healthineers Company
See details and how to joinNCT05804318
Phase 1Taking people
A Study to Evaluate Safety, Tolerability and Preliminary Activity of AGX101 in Participants With Advanced Solid Tumors
Where
Fairfax, Houston, Los Angeles, Nashville, San Antonio, Sarasota, St Louis
Age
18 years and over
People
80
Run by
Angiex, Inc.
See details and how to joinNCT06440005