Prostate cancer trials in United States

In United States 655 Also abroad 1490

655 trials · From ClinicalTrials.gov, checked 15 November 2026. Ask the study team whether a trial fits you.

Phase 2Taking people
Pacritinib in Participants With Metastatic Castrate-Resistant Prostate Cancer That Progressed on or After Prior Treatment With Androgen Receptor Signaling Inhibitors
Where
Milwaukee
Age
18 years and over
People
32
Run by
Medical College of Wisconsin
See details and how to joinNCT07226713
No phaseTaking people
Longitudinal Advanced Prostate Cancer Cohort (LAPCC)
Where
Los Angeles
Age
18 years and over
People
300
Run by
University of Southern California
See details and how to joinNCT06067295
Phase 2Taking people
Low Dose Naltrexone (LDN) for Management of Fatigue in Prostate Cancer Patients on Androgen Deprivation Therapy (ADT)
Where
Little Rock
Age
18 years and over
People
60
Run by
University of Arkansas
See details and how to joinNCT07224009
No phaseTaking people
Comparing Standard of Care Biopsy System to a Novel Biopsy Needle System by Computational Pathologic Analysis
Where
Durham, Hardeeville, New York
Age
18 years and over
People
200
Run by
Uro-1 Medical
See details and how to joinNCT06830265
No phaseTaking people
Patient Navigation Program to Improve Clinical Trial Enrollment in Cancer Patients
Where
Baltimore, Chambersburg
Age
18 years and over
People
90
Run by
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
See details and how to joinNCT06138067
Phase 2Taking people
A Phase 2 Study to Evaluate the Effects of ASP5541 in Participants With Prostate Cancer
Where
Albuquerque, Charlottesville, Chicago Ridge, Cincinnati, Evanston, Huntsville, Madison, Myrtle Beach, Nashville, New Orleans, San Diego, Tampa
Age
18 years and over
People
218 worldwide
Run by
Astellas Pharma Global Development, Inc.
See details and how to joinNCT07005154 · EU 2024-517653-27-00
Phase 1Taking people
Study of JANX014 in Subjects With Metastatic Castration-Resistant Prostate Cancer
Where
Charleston, Dallas, Greenville, La Jolla, Nashville, St Louis
Age
18 years and over
People
43
Run by
Janux Therapeutics
See details and how to joinNCT07545811
Phase 2Taking people
Short Course ADT for High Risk Low/Intermediate Risk ARTERA Prostate Cancer
Where
New York
Age
18 years and over
People
90
Run by
NYU Langone Health
See details and how to joinNCT07801664
No phaseTaking people
Prostate Active Surveillance Study
Where
Ann Arbor, Atlanta, Boston, Norfolk, San Antonio, San Francisco, Seattle, Stanford
Age
21 years and over
People
3,000 worldwide
Run by
University of Washington
See details and how to joinNCT00756665
No phaseTaking people
Serial MRI Scans During Radiation Therapy
Where
Boston
Age
18 years and over
People
149
Run by
Dana-Farber Cancer Institute
See details and how to joinNCT04188535
Phase 1Taking people
Study to Assess Safety, Tolerability and Activity of DSB2455 in Participants With Advanced Malignancies
Where
Houston, New Haven, New York, Sacramento
Age
18 years and over
People
180 worldwide
Run by
Duke Street Bio Ltd
See details and how to joinNCT06458712 · EU 2023-508805-26-00
Phase 1/2Taking people
A Study to Learn How Safe AZD6621 is, How Well it Works, and How it Moves Throughout the Body Over Time, in Adult Male Participants With Metastatic Prostate Cancer
Where
Boston, Commack, Grand Rapids, Orlando, Providence, Tampa
Age
18 years and over
People
52 worldwide
Run by
AstraZeneca
See details and how to joinNCT07192614 · EU 2025-520626-37-00
Phase 1/2Not yet taking people in United States
Neoadjuvant Intraprostatic OnabotulinumtoxinA Before Radical Prostatectomy for High-Risk Localized Prostate Cancer
Where
Houston
Age
45 years to 80 years
People
30
Run by
The Methodist Hospital Research Institute
See details and how to joinNCT07796490
No phaseTaking people
MRI-Based Machine Learning Approach Versus Radiologist MRI Reading for the Detection of Prostate Cancer, The PRIMER Trial
Where
Los Angeles
Age
20 years and over
People
130
Run by
University of Southern California
See details and how to joinNCT07162194
Phase 2Taking people
A Study of Enzalutamide Plus the Glucocorticoid Receptor Antagonist Relacorilant Versus Placebo for Patients With High-risk Localized Prostate Cancer
Where
Chicago, Dallas, Evanston, Portland
Age
18 years and over
People
90
Run by
University of Chicago
See details and how to joinNCT05726292
Phase 1/2Taking people
Safety and Efficacy of AGN-INM176 in Prostate Patients With Rising PSA
Where
Hershey
Age
40 years and over
People
45
Run by
Milton S. Hershey Medical Center
See details and how to joinNCT06600698
Phase 2Taking people
A Study of Tarlatamab for People With Prostate Cancer
Where
Basking Ridge, Commack, Harrison, Middletown, Montvale, New York, Philadelphia, San Diego, San Francisco, Uniondale
Age
18 years and over
People
32
Run by
Memorial Sloan Kettering Cancer Center
See details and how to joinNCT07111507
Phase 1Taking people
Comparison of 177Lu-PSMA-617 and 225Ac-PSMA-617
Where
San Francisco
Age
18 years and over
People
45
Run by
Thomas Hope
See details and how to joinNCT07054346
Phase 2Taking people
Zanzalintinib in Men With Aggressive Variant Prostate Cancer
Where
Milwaukee
Age
18 years and over
People
30
Run by
Deepak Kilari
See details and how to joinNCT07218666
Early phase 1Not yet taking people in United States
Evaluation of the Distribution of 64Cu/68Ga Labeled CM500 in Healthy Volunteers and Patients With Cancer
Where
Boston, Grand Rapids, New York
Age
18 years and over
People
40
Run by
Lumina Pharmaceuticals Inc
See details and how to joinNCT07781852
No phaseTaking people
Testing the Effects of Exercise on Colorectal Cancer Development After Treatment With Pelvic Radiation Therapy for Prostate Cancer
Where
Duarte, Irvine
Age
40 years to 80 years
People
30
Run by
City of Hope Medical Center
See details and how to joinNCT07790718
No phaseTaking people
COMPASS Study for Metastatic Castration-resistant Prostate Cancer
Where
Ann Arbor, Durham, Madison, San Francisco
Age
18 years and over
People
48
Run by
Duke University
See details and how to joinNCT07050433
No phaseTaking people
PRISM Study: Prostate Recurrence Detection Using Imaging With PSMA PET/MRI Post-high Intensity Focused Ultrasound
Where
New York
Age
40 years to 95 years
People
60
Run by
NYU Langone Health
See details and how to joinNCT07184970
No phaseTaking people
Transrectal Ultrasound Robot-Assisted Prostate Biopsy
Where
Baltimore
Age
45 years to 75 years
People
483
Run by
Johns Hopkins University
See details and how to joinNCT02871726
Phase 3Not yet taking people in United States
Multiparametric Ultrasound for the Diagnosis of Clinically Significant Prostate Cancer
Where
Philadelphia
Age
18 years and over
People
300 worldwide
Run by
Thomas Jefferson University
See details and how to joinNCT06024772