Prostate cancer trials in United States

In United States 655 Also abroad 1489

655 trials · From ClinicalTrials.gov, checked 13 November 2026. Ask the study team whether a trial fits you.

Phase 1/2Taking people
A Phase I/II Study of PDS01ADC With Docetaxel and Abiraterone in Adults With Metastatic Castration Sensitive and PDS01ADC With Docetaxel in Castration Resistant Prostate Cancer
Where
Bethesda
Age
18 years to 110 years
People
86
Run by
National Cancer Institute (NCI)
See details and how to joinNCT04633252
Phase 1Taking people
Study of JANX007 in Subjects With Metastatic Castration-Resistant Prostate Cancer (ENGAGER-PSMA-01)
Where
Baltimore, Birmingham, Charleston, Chicago, Cincinnati, Columbus, Dallas, Hershey, Houston, Jacksonville, Lake Success, Los Angeles, Madison, Milwaukee, Mineola, Minneapolis, Nashville, New Haven, Newport Beach, New York, Philadelphia, Phoenix, Pittsburgh, Providence, Rochester, Sacramento, San Francisco, St Louis, The Bronx
Age
18 years to 100 years
People
272 worldwide
Run by
Janux Therapeutics
See details and how to joinNCT05519449 · EU 2026-526777-42-00
No phaseTaking people
Extending Prostate Genetic Awareness, Navigation, and Delivery: The EXPAND Network
Where
Philadelphia
Age
18 years and over
People
30
Run by
Thomas Jefferson University
See details and how to joinNCT05627219
Phase 1Taking people
Pilot Study for Detection of PSMA-Low CRPC-NE Tumors With Fluciclovine PET/CT
Where
Boston
Age
18 years and over
People
30
Run by
Brigham and Women's Hospital
See details and how to joinNCT06062745
No phaseTaking people
Exercise in Prostate Cancer
Where
Baltimore
Age
18 years and over
People
20
Run by
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
See details and how to joinNCT06165302
Phase 2Taking people
Phase II Non-Randomized Study Evaluating POSLUMA-PSMA PET Response After Oligo- Metastatic/Progressive-directed Treatment With Radiotherapy (PROMPT-R)
Where
Duarte
Age
18 years and over
People
50
Run by
City of Hope Medical Center
See details and how to joinNCT07210086
Phase 1/2Taking people
Study of GVV858 as a Single Agent or in Combination With Endocrine Therapy in Patients With HR+/HER2- Breast Cancer and Other Advanced Solid Tumors
Where
Atlanta, Nashville, San Antonio
Age
18 years and over
People
205 worldwide
Run by
Novartis Pharmaceuticals
See details and how to joinNCT07288359
Early phase 1Taking people
FTT PET/CT in Metastatic Prostate Cancer
Where
Philadelphia
Age
18 years and over
People
30
Run by
Abramson Cancer Center at Penn Medicine
See details and how to joinNCT05242744
Phase 1Taking people
A Study of MGC026 in Participants With Advanced Solid Tumors
Where
Grand Rapids, Houston, Lake Success, Los Angeles, Portland, West Valley City
Age
18 years and over
People
394 worldwide
Run by
MacroGenics
See details and how to joinNCT06242470
Phase 3Enrolling by invitation
Long-Term Extension Study for Participants Previously Enrolled in an Exelixis-Sponsored Study
Where
Bay Shore, Houston, Kettering, Memphis
People
5,000
Run by
Exelixis
See details and how to joinNCT07620574 · EU 2026-525795-26-00
No phaseTaking people
A Pilot Study of Total-body PET Using FDA-approved Radiotracers Beyond 18F-FDG
Where
Sacramento
Age
18 years and over
People
9
Run by
University of California, Davis
See details and how to joinNCT05160480
Phase 1Taking people
Safety, Pharmacokinetics, and Preliminary Efficacy of VIR-5500 (AMX-500) in Prostate Cancer
Where
Duarte, Fairfax, Houston, Irvine, Orange, Palo Alto, San Francisco, Seattle, Zion
Age
18 years and over
People
347 worldwide
Run by
Astellas Pharma Global Development, Inc.
See details and how to joinNCT05997615 · EU 2023-503495-24-00
Phase 2Taking people
Placebo-Controlled Trial of Urolithin A Supplementation in Men With Prostate Cancer Undergoing Radical Prostatectomy, URO-PRO Trial
Where
Chicago, Durham, Los Angeles, Madison
Age
18 years and over
People
90
Run by
National Cancer Institute (NCI)
See details and how to joinNCT06022822
No phaseTaking people
Precision-Based Genomics in Prostate Cancer
Where
Ann Arbor, Bethesda, Boston, Evanston, La Jolla, New York, Portland, San Francisco, Seattle
Age
18 years to 120 years
People
2,000
Run by
National Cancer Institute (NCI)
See details and how to joinNCT04706663
Phase 2Taking people
A Single-Arm Phase II Study of Neoadjuvant Intensified Androgen Deprivation (Leuprolide and Abiraterone Acetate) in Combination With AKT Inhibition (Capivasertib) for High-Risk Localized Prostate Cancer With PTEN Loss
Where
Charleston, Chicago, Houston, Portland, San Antonio, Seattle, St Louis, The Bronx, West Los Angeles
Age
18 years and over
People
30
Run by
VA Office of Research and Development
See details and how to joinNCT05593497
Phase 2Taking people
A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors
Where
Baltimore, Buffalo, Chicago, Duarte, Houston, Kissimmee, Nashville, New Haven, New York, Rockville, Saint Louis Park, Saint Paul, Seattle, St Louis
Age
18 years and over
People
740 worldwide
Run by
Daiichi Sankyo
See details and how to joinNCT06172478 · EU 2023-507641-29-00
No phaseTaking people
Real World Prostate Cancer Registry
Where
Cincinnati
Age
18 years and over
People
1,000
Run by
Cincinnati Cancer Advisors
See details and how to joinNCT06355336
No phaseTaking people
Assessing the Feasibility of Web-based Insomnia Treatment Among Prostate Cancer Survivors
Where
Washington D.C.
Age
21 years and over
People
40
Run by
Georgetown University
See details and how to joinNCT07128927
Phase 1Taking people
A Study of Valemetostat (DS-3201b) in Combination With Darolutamide in Metastatic Castration Resistant Prostate Cancer (mCRPC)
Where
Boston, Fairfax, Grand Rapids, La Jolla, Lake Success, Milwaukee, Myrtle Beach, Newton, San Antonio
Age
18 years and over
People
60 worldwide
Run by
Daiichi Sankyo
See details and how to joinNCT07244341 · EU 2025-522512-16-00
Phase 1/2Taking people
A Study of ASP388B Given by Itself and With Standard Therapies in Participants With Solid Tumors
Where
Fairfax, Lake Success
Age
18 years and over
People
392 worldwide
Run by
Astellas Pharma Global Development, Inc.
See details and how to joinNCT07730021 · EU 2026-525938-31-00
Phase 3Taking people
Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With High Risk Prostate Cancer
Where
‘Aiea, Akron, Albuquerque, Alton, American Fork, Ames, Ann Arbor, Antigo, Antioch, Ashland, Atlanta, Aurora, Aventura, Avon, Baltimore, Barrington, Bath, Baton Rouge, Bay Pines, Bay Shore, Beachwood, Beaver, Bel Air, Belleville, Bellevue, Bellingham, Bemidji, Bend, Berlin Corners, Beverly Hills, Billings, Birmingham, Bloomington, Boston, Brainerd, Brighton, Brooklyn, Brownstown, Burlington, Canandaigua, Canton, Cape Girardeau, Carlisle, Carthage, Cedar City, Chadds Ford, Chambersburg, Chaska, Chelsea, Chicago, City of Saint Peters, Clackamas, Cleveland, Clinton Township, Colorado Springs, Columbia, Columbus, Conroe, Coon Rapids, Creve Coeur, Crystal Lake, Dansville, Danville, Daytona Beach, Dearborn, Decatur, Deer River, DeKalb, Delaware, Detroit, Downers Grove, Dublin, Duluth, Durham, Easton, Edina, Effingham, Elgin, Elizabeth, Elizabethtown, Elmhurst, Ephrata, Erie, ‘Ewa Beach, Fargo, Farmington, Farrell, Fishersville, Flint, Florence, Flushing, Forest Hills, Fort Sam Houston, Fremont, Fresno, Gaffney, Galesburg, Geneva, Germantown, Gettysburg, Glen Burnie, Gonzales, Goshen, Grafton, Grand Forks, Grand Rapids, Great Falls, Green Bay, Greenlawn, Greensburg, Greenwood, Greer, Harrisburg, Havre, Hayward, Hazel Crest, Hershey, Hibbing, Highlands Ranch, Honolulu, Houston, Huntington, Independence, Irvine, Jackson, Jacksonville, Jersey City, Johnson Creek, Jupiter, Kailua, Kansas City, Kenosha, Kewanee, Lake Success, Land O' Lakes, Lansing, Largo, Lawrence, League City, Lebanon, Lee's Summit, Lewisburg, Lexington, Libertyville, Lihue, Little Rock, Livingston, Livonia, Logan, Long Branch, Los Angeles, Louisville, Macomb, Madison, Mansfield, Marinette, Marion, Marquette, Mattoon, Mayfield Heights, Mechanicsburg, Mechanicsville, Menomonee Falls, Mentor, Miami Beach, Midlothian, Milford, Milwaukee, Minneapolis, Modesto, Monroeville, Morgantown, Mount Kisco, Murray, Naperville, Newark, New Bern, New Brunswick, New Richmond, New York, Niles, Novi, Oak Brook, Oak Creek, Oakland, Oak Lawn, Oceanside, O'Fallon, Ogden, Oklahoma City, Olathe, Omaha, Orange, Orland Park, Oshkosh, Oswego, Ottawa, Overland Park, Palos Heights, Paramus, Parkersburg, Park Ridge, Parma, Pekin, Pennington, Peoria, Peru, Pittsburgh, Portland, Pottsville, Princeton, Provo, Racine, Rancho Cordova, Ravenna, Redwood City, Reno, Rhinelander, Richmond, Riverton, Rochester, Rohnert Park, Rolla, Roseville, Royal Oak, Ruskin, Sacramento, Saginaw, Saint Johnsbury, Saint Joseph, Saint Louis Park, Saint Paul, Salt Lake City, Sandstone, Sandusky, Sanford, San Francisco, San Jose, San Leandro, San Rafael, Santa Clara, Santa Rosa, Scarborough, Seattle, Sheboygan, Shiloh, Sioux Falls, Sleepy Hollow, South Charleston, South San Francisco, South Weymouth, Spartanburg, Spooner, Springfield, Staten Island, Stevens Point, St. George, Stillwater, St Louis, Stockton, Stony Brook, Strongsville, Sturgeon Bay, Sugar Land, Summit, Superior, Sylvania, Syracuse, Tampa, Toledo, Toms River, Topeka, Torrance, Towson, Traverse City, Troy, Tuscaloosa, Two Rivers, Union, Urbana, Vacaville, Valhalla, Vallejo, Valley Stream, Verona, Virginia, Waconia, Walnut Creek, Warrenville, Washington D.C., Wausau, Wauwatosa, Webster, Wesley Chapel, West Allis, West Bend, West Bloomfield, Westerville, West Reading, Westwood, Wheeling, Wichita, Wilkes-Barre, Wilmington, Wisconsin Rapids, Wooster, Wyandotte, Wyoming, York
Age
18 years and over
People
1,500 worldwide
Run by
NRG Oncology
See details and how to joinNCT05946213
No phaseTaking people
Exercise-induced Steroid Changes in Active Surveillance for Prostate Cancer
Where
Miami
Age
18 years to 80 years
People
50
Run by
University of Miami
See details and how to joinNCT07518888
Phase 1Taking people
A Study to Investigate the Safety and Tolerability of Oral INR731 Single Agent or in Combination With Androgen Receptor Pathway Inhibitor (ARPI) in Patients With Metastatic Prostate Cancer
Where
Boston, Dallas
Age
18 years and over
People
208 worldwide
Run by
Novartis Pharmaceuticals
See details and how to joinNCT07570979
Early phase 1Taking people
Chemical-Shift-Encoded MRI for Active Bone Marrow Dosimetry in Radiopharmaceutical Therapy
Where
Madison
Age
18 years and over
People
15
Run by
University of Wisconsin, Madison
See details and how to joinNCT07609225
No phaseTaking people
Impact of DNA Repair Pathway Alterations on Sensitivity to Radium-223 in Bone Metastatic Castration-resistant Prostate Cancer
Where
Baltimore, Bozeman, Madison, Seattle
Age
18 years and over
People
48
Run by
University of Washington
See details and how to joinNCT04489719