Prostate cancer trials in United States

In United States 655 Also abroad 1490

655 trials · From ClinicalTrials.gov, checked 14 November 2026. Ask the study team whether a trial fits you.

Phase 3Taking people
Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With High Risk Prostate Cancer
Where
‘Aiea, Akron, Albuquerque, Alton, American Fork, Ames, Ann Arbor, Antigo, Antioch, Ashland, Atlanta, Aurora, Aventura, Avon, Baltimore, Barrington, Bath, Baton Rouge, Bay Pines, Bay Shore, Beachwood, Beaver, Bel Air, Belleville, Bellevue, Bellingham, Bemidji, Bend, Berlin Corners, Beverly Hills, Billings, Birmingham, Bloomington, Boston, Brainerd, Brighton, Brooklyn, Brownstown, Burlington, Canandaigua, Canton, Cape Girardeau, Carlisle, Carthage, Cedar City, Chadds Ford, Chambersburg, Chaska, Chelsea, Chicago, City of Saint Peters, Clackamas, Cleveland, Clinton Township, Colorado Springs, Columbia, Columbus, Conroe, Coon Rapids, Creve Coeur, Crystal Lake, Dansville, Danville, Daytona Beach, Dearborn, Decatur, Deer River, DeKalb, Delaware, Detroit, Downers Grove, Dublin, Duluth, Durham, Easton, Edina, Effingham, Elgin, Elizabeth, Elizabethtown, Elmhurst, Ephrata, Erie, ‘Ewa Beach, Fargo, Farmington, Farrell, Fishersville, Flint, Florence, Flushing, Forest Hills, Fort Sam Houston, Fremont, Fresno, Gaffney, Galesburg, Geneva, Germantown, Gettysburg, Glen Burnie, Gonzales, Goshen, Grafton, Grand Forks, Grand Rapids, Great Falls, Green Bay, Greenlawn, Greensburg, Greenwood, Greer, Harrisburg, Havre, Hayward, Hazel Crest, Hershey, Hibbing, Highlands Ranch, Honolulu, Houston, Huntington, Independence, Irvine, Jackson, Jacksonville, Jersey City, Johnson Creek, Jupiter, Kailua, Kansas City, Kenosha, Kewanee, Lake Success, Land O' Lakes, Lansing, Largo, Lawrence, League City, Lebanon, Lee's Summit, Lewisburg, Lexington, Libertyville, Lihue, Little Rock, Livingston, Livonia, Logan, Long Branch, Los Angeles, Louisville, Macomb, Madison, Mansfield, Marinette, Marion, Marquette, Mattoon, Mayfield Heights, Mechanicsburg, Mechanicsville, Menomonee Falls, Mentor, Miami Beach, Midlothian, Milford, Milwaukee, Minneapolis, Modesto, Monroeville, Morgantown, Mount Kisco, Murray, Naperville, Newark, New Bern, New Brunswick, New Richmond, New York, Niles, Novi, Oak Brook, Oak Creek, Oakland, Oak Lawn, Oceanside, O'Fallon, Ogden, Oklahoma City, Olathe, Omaha, Orange, Orland Park, Oshkosh, Oswego, Ottawa, Overland Park, Palos Heights, Paramus, Parkersburg, Park Ridge, Parma, Pekin, Pennington, Peoria, Peru, Pittsburgh, Portland, Pottsville, Princeton, Provo, Racine, Rancho Cordova, Ravenna, Redwood City, Reno, Rhinelander, Richmond, Riverton, Rochester, Rohnert Park, Rolla, Roseville, Royal Oak, Ruskin, Sacramento, Saginaw, Saint Johnsbury, Saint Joseph, Saint Louis Park, Saint Paul, Salt Lake City, Sandstone, Sandusky, Sanford, San Francisco, San Jose, San Leandro, San Rafael, Santa Clara, Santa Rosa, Scarborough, Seattle, Sheboygan, Shiloh, Sioux Falls, Sleepy Hollow, South Charleston, South San Francisco, South Weymouth, Spartanburg, Spooner, Springfield, Staten Island, Stevens Point, St. George, Stillwater, St Louis, Stockton, Stony Brook, Strongsville, Sturgeon Bay, Sugar Land, Summit, Superior, Sylvania, Syracuse, Tampa, Toledo, Toms River, Topeka, Torrance, Towson, Traverse City, Troy, Tuscaloosa, Two Rivers, Union, Urbana, Vacaville, Valhalla, Vallejo, Valley Stream, Verona, Virginia, Waconia, Walnut Creek, Warrenville, Washington D.C., Wausau, Wauwatosa, Webster, Wesley Chapel, West Allis, West Bend, West Bloomfield, Westerville, West Reading, Westwood, Wheeling, Wichita, Wilkes-Barre, Wilmington, Wisconsin Rapids, Wooster, Wyandotte, Wyoming, York
Age
18 years and over
People
1,500 worldwide
Run by
NRG Oncology
See details and how to joinNCT05946213
No phaseTaking people
Exercise-induced Steroid Changes in Active Surveillance for Prostate Cancer
Where
Miami
Age
18 years to 80 years
People
50
Run by
University of Miami
See details and how to joinNCT07518888
Phase 1Taking people
A Study to Investigate the Safety and Tolerability of Oral INR731 Single Agent or in Combination With Androgen Receptor Pathway Inhibitor (ARPI) in Patients With Metastatic Prostate Cancer
Where
Boston, Dallas
Age
18 years and over
People
208 worldwide
Run by
Novartis Pharmaceuticals
See details and how to joinNCT07570979
Early phase 1Taking people
Chemical-Shift-Encoded MRI for Active Bone Marrow Dosimetry in Radiopharmaceutical Therapy
Where
Madison
Age
18 years and over
People
15
Run by
University of Wisconsin, Madison
See details and how to joinNCT07609225
No phaseTaking people
Impact of DNA Repair Pathway Alterations on Sensitivity to Radium-223 in Bone Metastatic Castration-resistant Prostate Cancer
Where
Baltimore, Bozeman, Madison, Seattle
Age
18 years and over
People
48
Run by
University of Washington
See details and how to joinNCT04489719
No phaseTaking people
Peer Navigation for the Support of Metastatic Prostate Cancer Patients Undergoing Genetic Evaluation
Where
Philadelphia
Age
18 years and over
People
120
Run by
Thomas Jefferson University
See details and how to joinNCT05487846
Phase 1/2Taking people
Study of AZD0516 as Monotherapy and in Combination in Participants With Metastatic Prostate Cancer
Where
Ann Arbor, Boston, Buffalo, Detroit, Fayetteville, Houston, Los Angeles, Myrtle Beach, New York, Providence, Towson
Age
18 years to 130 years
People
283 worldwide
Run by
AstraZeneca
See details and how to joinNCT07181161 · EU 2024-520026-11-00
Phase 1Taking people
A Study of SHY-ONC6, a Novel Proteasome Inhibitor, in Adults With Advanced or Metastatic Solid Tumors
Where
Houston, San Antonio, Scottsdale
Age
18 years and over
People
30
Run by
SHY Therapeutics
See details and how to joinNCT07705334
Phase 2/3Taking people
Safety and Efficacy of OTL78
Where
Carmel, Indianapolis
Age
18 years and over
People
45
Run by
Clinton Bahler
See details and how to joinNCT07725523
No phaseNot yet taking people in United States
SURPASS: Stereotactic Ultra-hypofractionated Radiotherapy for Post-prostatectomy Patients: Adaptive Salvage SBRT
Where
New York
Age
18 years and over
People
30
Run by
NYU Langone Health
See details and how to joinNCT07888283
Phase 2Taking people
Study of PF-07248144 in Advanced or Metastatic Solid Tumors
Where
Conroe, Edgewood, Fort Lauderdale, Houston, League City, Los Angeles, Louisville, Nashville, New Haven, San Antonio, San Francisco, Scottsdale, Seattle, Sugar Land
Age
18 years and over
People
320 worldwide
Run by
Pfizer
See details and how to joinNCT04606446
Phase 1/2Taking people
A Phase 1/2a Study of DB-1311/BNT324 in Advanced/Metastatic Solid Tumors
Where
Atlanta, Austin, Canton, Celebration, Charleston, Cincinnati, Dallas, Dayton, Detroit, Fairfax, Greenville, Las Vegas, Los Angeles, Louisville, Margate, Nashville, New York, Orlando, Plantation, Saint Paul, Santa Monica, Spokane, Tamarac, Tucson
Age
18 years and over
People
862 worldwide
Run by
DualityBio Inc.
See details and how to joinNCT05914116
Phase 3Taking people
An Open-label Study Comparing Lutetium (177Lu) Vipivotide Tetraxetan Versus Observation in PSMA Positive OMPC.
Where
Atlanta, Baltimore, Baton Rouge, Boston, Chicago, Dallas, Denver, Des Moines, Elk Grove, El Paso, Fayetteville, Grand Rapids, Greenville, Jacksonville, Kansas City, Kettering, Los Angeles, Metairie, Myrtle Beach, Nashville, New York, Norfolk, Omaha, Palo Alto, Pensacola, Rochester, Royal Oak, San Francisco, Springfield, St Louis, Syracuse, The Bronx, Wytheville
Age
18 years to 100 years
People
450 worldwide
Run by
Novartis Pharmaceuticals
See details and how to joinNCT05939414 · EU 2022-502956-29-00
No phaseNot yet taking people in United States
Veteran Peer Navigators to Promote Shared Decision Making for PSA Screening
Where
New York
Age
40 years to 69 years
People
228
Run by
VA Office of Research and Development
See details and how to joinNCT06549036
Phase 2Not yet taking people in United States
[18F]Fluorthanatrace - Positron Emission Tomography (FTT-PET) and ctDNA to Predict Response to PARP Inhibitor Therapy in Metastatic Prostate Cancer (mPC)
Where
Houston, Philadelphia, St Louis
Age
18 years and over
People
75
Run by
Washington University School of Medicine
See details and how to joinNCT07723651
No phaseTaking people
Circulating Tumor Cell Analysis in Patients With Localized Prostate Cancer Undergoing Prostatectomy
Where
Boston
Age
18 years and over
People
200
Run by
Massachusetts General Hospital
See details and how to joinNCT01961713
Phase 2Taking people
A Phase II Study Evaluating T-Cell Clonality After Stereotactic Body Radiation Therapy Alone and in Combination With the Immunocytokine PDS01ADC in Localized High and Intermediate Risk Prostate Cancer Treated With Androgen Deprivation Therapy
Where
Bethesda
Age
18 years and over
People
65
Run by
National Cancer Institute (NCI)
See details and how to joinNCT05361798
Phase 4Taking people
Evaluation of the Change in PSMA Expression in Prostate Cancer in Response to Hormonal Therapy
Where
Portland
Age
18 years and over
People
80
Run by
OHSU Knight Cancer Institute
See details and how to joinNCT05919329
Phase 3Taking people
A Study of Opevesostat (MK-5684) Versus Alternative Next-generation Hormonal Agent (NHA) in Metastatic Castration-resistant Prostate Cancer (mCRPC) Post One NHA (MK-5684-004)
Where
Aberdeen, Atlanta, Aurora, Austin, Bala-Cynwyd, Baltimore, Billings, Carmel, Charleston, Charlottesville, Cleveland, Dallas, Detroit, Elmhurst, Fairfax, Fort Myers, Gahanna, Germantown, Grand Rapids, Highlands Ranch, Houston, Irvine, Lakewood, Las Vegas, Lexington, Lone Tree, Los Angeles, Marshall, Miami Beach, Milwaukee, Mitchell, Naperville, New Brunswick, New Haven, Omaha, Orange, Palo Alto, Pembroke Pines, Peoria, Philadelphia, Pierre, Redlands, Richmond, Riverside, Roanoke, Sacramento, Saint Louis Park, Saint Paul, San Francisco, Sioux Falls, Spokane, Syracuse, Towson, Tucson, Vallejo, Vancouver, Washington D.C., Yankton, Zanesville
Age
18 years and over
People
1,314 worldwide
Run by
Merck Sharp & Dohme LLC
See details and how to joinNCT06136650 · EU 2023-504957-11-00
Phase 1Taking people
Safety, PK and Efficacy of QXL138AM in Patients With Solid Tumors and Multiple Myeloma
Where
Atlanta, Denver, Los Angeles, Milwaukee, Newport, New York, Rochester, San Antonio
Age
18 years and over
People
100
Run by
Nammi Therapeutics Inc
See details and how to joinNCT06582017
Phase 1Taking people
A Clinical Study of KTX-2001 in Subjects With Metastatic Castration-Resistant Prostate Cancer (STRIKE-001)
Where
Columbus, Durham, Madison, Miami, Myrtle Beach, New Hyde Park, New York, Port Saint Lucie, Rochester, San Antonio, San Francisco
Age
18 years and over
People
144
Run by
K36 Therapeutics, Inc.
See details and how to joinNCT07103018
Phase 3Taking people
A Study of Xaluritamig Plus Abiraterone Versus Investigator's Choice in Participants With Chemotherapy-naïve Metastatic Castration-resistant Prostate Cancer
Where
Arlington, Baltimore, Charlottesville, Chicago, Cincinnati, Columbus, Dallas, Dayton, Decatur, Denver, Duarte, East Syracuse, Fullerton, Goodyear, Hartford, Houston, Lansing, Leesburg, Los Angeles, Louisville, Midlothian, Minneapolis, Myrtle Beach, Nashville, Newark, Newnan, New York, Norfolk, Oklahoma City, Orange, Pittsburgh, Salem, San Francisco, Santa Monica, Tacoma, Tampa, Tucson, Tyler, Westwood, Zion
Age
18 years and over
People
750 worldwide
Run by
Amgen
See details and how to joinNCT07213674
Phase 2Not yet taking people in United States
HRT-PC Trial: Hormone Recovery After Treatment for Prostate Cancer Trial. An Open-label Phase II Study of Clomiphene Citrate in Patients With Persistent Hypogonadism After ADT for Treatment of Localized Prostate Cancer
Where
Omaha
Age
19 years and over
People
83
Run by
University of Nebraska
See details and how to joinNCT07882862
No phaseTaking people
Light Therapy and Occupational Therapy Fatigue Management-Based Intervention for Patients With Genitourinary Cancers
Where
Duarte
Age
18 years and over
People
224
Run by
City of Hope Medical Center
See details and how to joinNCT05519878
Phase 2Taking people
Abi/Pred + ADT vs ADT in PSMA-Positive, Conventionally Node-Negative Prostate Cancer
Where
Omaha
Age
30 years and over
People
140
Run by
University of Nebraska
See details and how to joinNCT07237269