Pulmonary arterial hypertension trials in Spain

In Spain 28 Also abroad 305

28 trials · From ClinicalTrials.gov and EU CTIS (euclinicaltrials.eu), checked 11 November 2026. Ask the study team whether a trial fits you.

Phase 1/2Taking people
A Study to Learn About the Treatment LTP001 in Healthy Participants (Part A) and in Participants With PAH (Part B)
Where
Barcelona, Huelva, Las Palmas de Gran Canaria, Málaga, Marbella, Santiago de Compostela, Sevilla, Toledo
Age
18 years and over
People
85 worldwide
Run by
Novartis Pharma AG
See details and how to join2024-513613-12-00 · EU 2024-513613-12-00
Phase 3Taking people
An Open-Label Extension Study of Treprostinil Palmitil Inhalation Powder (TPIP) in Participants With Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)
Where
Madrid
Age
18 years and over
People
344 worldwide
Run by
Insmed Incorporated
See details and how to joinNCT07234032 · EU 2025-521769-29-00
No phaseNot yet taking people in Spain
Home-based Inspiratory Muscle Training in Pulmonary Hypertension
Where
Madrid
Age
18 years and over
People
40
Run by
Universidad Complutense de Madrid
See details and how to joinNCT07917416
Phase 3Taking people
A Study Providing Treatment Access in Participants With Pulmonary Hypertension Completing a Parent Study and Having no Other Option
Where
Madrid
Age
2 years and over
People
280 worldwide
Run by
Actelion
See details and how to joinNCT05179876 · EU 2023-506791-27-00
Phase 2Taking people
Study to Evaluate Sotatercept (MK-7962) in Children With Pulmonary Arterial Hypertension (PAH) (MK-7962-008)
Where
Barcelona, Madrid, Valencia
Age
1 year to 17 years
People
42 worldwide
Run by
Merck Sharp & Dohme LLC
See details and how to joinNCT05587712 · EU 2023-504861-22-00
Phase 1/2Taking people
A Study of HS235 for Treatment of Pulmonary Arterial Hypertension (PAH) in Adults
Where
Barcelona, Madrid
Age
18 years and over
People
90 worldwide
Run by
35Pharma Inc., a GSK company
See details and how to joinNCT07143448
Phase 4Taking people
Initial Triple Therapy Including Parenteral Treprostinil vs Initial Double Oral Therapy in PAH Group I Patients
Where
Barcelona, Madrid
Age
18 years to 75 years
People
110 worldwide
Run by
AOP Orphan Pharmaceuticals AG
See details and how to joinNCT06317805 · EU 2023-504351-26-01
Phase 3Taking people
Investigational Trial to Evaluate Safety and Tolerability of Treprostinil in Children Diagnosed With PAH
Where
Barcelona, Madrid
Age
Up to 18 years
People
20 worldwide
Run by
AOP Orphan Pharmaceuticals AG
See details and how to joinNCT06350032 · EU 2023-505082-91-00
No phaseEnrolling by invitation
A Prospective Non-interventional Observational Study to Observe Long-term Treatment and Outcomes in Pulmonary Arterial Hypertension (PAH) Patients
Where
Barcelona, Madrid
Age
18 years and over
People
110 worldwide
Run by
AOP Orphan Pharmaceuticals AG
See details and how to joinNCT06445673
Phase 2Taking people
Clinical Trial of NS-863 in Participants With Pulmonary Arterial Hypertension (PAH)
Where
Barcelona, Madrid, Palma, Santander, Toledo
Age
18 years to 75 years
People
135 worldwide
Run by
NS Pharma, Inc.
See details and how to joinNCT07441200 · EU 2025-525114-38-00
Phase 2Taking people
Study of TX000045 in Participants With Pulmonary Hypertension Due to Interstitial Lung Disease
Where
Barcelona, Madrid, Santander
Age
18 years to 80 years
People
25 worldwide
Run by
Tectonic Operating Company, Inc.
See details and how to joinNCT07473700
Phase 1/2Taking people
Phase 1b/2 Dose-Ranging Study of the Safety, PK, PD & Efficacy of the Activin Signaling Inhibitor HS235 vs placebo added to background therapy in PAH (SEASIde)
Where
Barcelona, Madrid, Marbella, Salamanca, Santander, Sevilla, Toledo
Age
18 years and over
People
50 worldwide
Run by
35Pharma Inc.
See details and how to join2025-523010-89-00 · EU 2025-523010-89-00
Phase 3Taking people
Efficacy and Safety Study of Treprostinil Palmitil Inhalation Powder (TPIP) in Participants With Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)
Where
Barcelona, L'Hospitalet de Llobregat, Madrid, Majadahonda, Palma de Mallorca, Santiago de Compostela, Seville, Toledo
Age
18 years and over
People
344 worldwide
Run by
Insmed Incorporated
See details and how to joinNCT07179380 · EU 2025-521558-40-00
Phase 2Taking people
Study of REGN13335 in Adult Participants With Pulmonary Arterial Hypertension (PAH)
Where
Barcelona, Madrid, Marbella, Salamanca, Santander, Toledo
Age
18 years and over
People
99 worldwide
Run by
Regeneron Pharmaceuticals
See details and how to joinNCT07318597 · EU 2024-514754-79-00
No phaseTaking people
Pulmonary Embolism Registry From Short-Term Emergency to Long-Term Follow-Up and Surveillance
Where
Madrid
Age
18 years and over
People
5,000 worldwide
Run by
Azienda Ospedaliero-Universitaria Careggi
See details and how to joinNCT07855679
Phase 3Taking people
A Phase 3 Study to Evaluate the Safety and Efficacy L606 in Participants With PH-ILD
Where
Barcelona, Santander
Age
18 years to 80 years
People
344 worldwide
Run by
Liquidia Technologies, Inc.
See details and how to joinNCT07285655
Phase 3Taking people
Open-label Extension Study of Seralutinib in Adult Subjects With PAH (PROSERA-EXT)
Where
Barcelona, Madrid, Majadahonda, Marbella, Palma, Salamanca, Santander, Sevilla, Toledo, Valencia
Age
18 years to 75 years
People
330 worldwide
Run by
Gossamer Bio USA, Inc.
See details and how to joinNCT06274801 · EU 2023-506334-75-00
Phase 3Taking people
A Study to Evaluate the Efficacy and Safety of Once Daily Treprostinil Palmitil Inhalation Powder (TPIP) in Participants With Pulmonary Arterial Hypertension (PAH)
Where
Madrid, Málaga, Palma, Santander, Santiago de Compostela, Sevilla, Toledo, Vigo
Age
18 years to 75 years
People
344 worldwide
Run by
Insmed Incorporated
See details and how to joinNCT07481981 · EU 2026-525265-48-00
Phase 2Taking people
A Study of ROC-101 in Patients With Pulmonary Arterial Hypertension (PAH) and Pulmonary Hypertension Associated With Interstitial Lung Disease (ILD-PH) (ROCSTAR STUDY)
Where
Madrid, Toledo
Age
18 years to 80 years
People
40 worldwide
Run by
AllRock Bio, Inc.
See details and how to joinNCT07175038 · EU 2025-522074-37-00
Phase 3Enrolling by invitation
A Study Evaluating the Long-Term Efficacy and Safety of Ralinepag in Subjects With PAH Via an Open-Label Extension
Where
Barcelona, Madrid, Valencia
Age
18 years and over
People
1,000 worldwide
Run by
United Therapeutics
See details and how to joinNCT03683186 · EU 2023-509305-68-00
Phase 3Taking people
An Adaptive Program of IKT-001 in Pulmonary Arterial Hypertension (PAH)
Where
Barcelona, Madrid, Málaga, Marbella Málaga, Salamanca, Santander, Sevilla, Toledo, Valencia
Age
18 years to 75 years
People
486 worldwide
Run by
Inhibikase Therapeutics
See details and how to joinNCT07365332 · EU 2024-520218-23-00
No phaseNot yet taking people in Spain
Telerehabilitation in Pulmonary Arterial Hypertension
Where
Málaga
Age
18 years and over
People
34
Run by
Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud
See details and how to joinNCT07799675
Phase 1/2Taking people
A Study to Learn About the Treatment LTP001 in Healthy Participants (Part A) and in Participants With PAH (Part B)
Where
Barcelona, Las Palmas de Gran C, Marbella, Santiago Compostela, Seville, Toledo
Age
18 years to 100 years
People
232 worldwide
Run by
Novartis Pharmaceuticals
See details and how to joinNCT06649110
Phase 3Not yet taking people in Spain
A Phase 3 Study of Extended-release Tacrolimus in Subjects With Pulmonary Arterial Hypertension and Functional Limitations
Where
Barcelona, Lugo, Madrid, Marbella, Toledo, Vigo
Age
18 years to 75 years
People
300 worldwide
Run by
VIVUS LLC
See details and how to joinNCT07612657 · EU 2025-524596-24-00
No phaseTaking people
Evaluation of the BMPR2-Activin Signaling Pathway in Group II Pulmonary Hypertension.
Where
Madrid
Age
18 years and over
People
150
Run by
Hospital General Universitario Gregorio Marañon
See details and how to joinNCT07537517