Pulmonary arterial hypertension trials in Italy

In Italy 18 Also abroad 305

18 trials · From ClinicalTrials.gov and EU CTIS (euclinicaltrials.eu), checked 11 November 2026. Ask the study team whether a trial fits you.

Phase 1/2Taking people
A Study to Learn About the Treatment LTP001 in Healthy Participants (Part A) and in Participants With PAH (Part B)
Where
Foggia, Ivrea, Monza, Palermo, Pavia, Rome, Sassari, Trieste
Age
18 years and over
People
85 worldwide
Run by
Novartis Pharma AG
See details and how to join2024-513613-12-00 · EU 2024-513613-12-00
No phaseTaking people
Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure
Where
Turin
Age
18 years and over
People
850 worldwide
Run by
Abbott Medical Devices
See details and how to joinNCT06526195
Phase 4Taking people
Initial Triple Therapy Including Parenteral Treprostinil vs Initial Double Oral Therapy in PAH Group I Patients
Where
Naples, Rome
Age
18 years to 75 years
People
110 worldwide
Run by
AOP Orphan Pharmaceuticals AG
See details and how to joinNCT06317805 · EU 2023-504351-26-01
No phaseEnrolling by invitation
A Prospective Non-interventional Observational Study to Observe Long-term Treatment and Outcomes in Pulmonary Arterial Hypertension (PAH) Patients
Where
Rome
Age
18 years and over
People
110 worldwide
Run by
AOP Orphan Pharmaceuticals AG
See details and how to joinNCT06445673
Phase 2Taking people
Clinical Trial of NS-863 in Participants With Pulmonary Arterial Hypertension (PAH)
Where
Brescia, Rome, Sassari, Trieste
Age
18 years to 75 years
People
135 worldwide
Run by
NS Pharma, Inc.
See details and how to joinNCT07441200 · EU 2025-525114-38-00
Phase 3Taking people
Efficacy and Safety Study of Treprostinil Palmitil Inhalation Powder (TPIP) in Participants With Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)
Where
Bologna, Catania, Milan, Modena, Monza, Naples, Pavia, Roma, Rozzano, Sassari
Age
18 years and over
People
344 worldwide
Run by
Insmed Incorporated
See details and how to joinNCT07179380 · EU 2025-521558-40-00
No phaseTaking people
Pulmonary Embolism Registry From Short-Term Emergency to Long-Term Follow-Up and Surveillance
Where
Bagno a Ripoli, Borgo San Lorenzo, Empoli, Florence, Lido di Camaiore, Naples, Perugia, Pescia, Pisa, Pistoia, Prato, Torino
Age
18 years and over
People
5,000 worldwide
Run by
Azienda Ospedaliero-Universitaria Careggi
See details and how to joinNCT07855679
Phase 3Taking people
A Phase 3 Study to Evaluate the Safety and Efficacy L606 in Participants With PH-ILD
Where
Genoa, Pavia, Rome
Age
18 years to 80 years
People
344 worldwide
Run by
Liquidia Technologies, Inc.
See details and how to joinNCT07285655
Phase 3Taking people
Open-label Extension Study of Seralutinib in Adult Subjects With PAH (PROSERA-EXT)
Where
Bologna, Naples, Pavia, Rome
Age
18 years to 75 years
People
330 worldwide
Run by
Gossamer Bio USA, Inc.
See details and how to joinNCT06274801 · EU 2023-506334-75-00
Phase 3Taking people
A Study to Evaluate the Efficacy and Safety of Once Daily Treprostinil Palmitil Inhalation Powder (TPIP) in Participants With Pulmonary Arterial Hypertension (PAH)
Where
Bologna, Milan, Monza, Naples, Palermo, Pavia, Rome, Sassari
Age
18 years to 75 years
People
344 worldwide
Run by
Insmed Incorporated
See details and how to joinNCT07481981 · EU 2026-525265-48-00
Phase 2Taking people
A Study of ROC-101 in Patients With Pulmonary Arterial Hypertension (PAH) and Pulmonary Hypertension Associated With Interstitial Lung Disease (ILD-PH) (ROCSTAR STUDY)
Where
Foggia, Palermo, Pavia, Rome
Age
18 years to 80 years
People
40 worldwide
Run by
AllRock Bio, Inc.
See details and how to joinNCT07175038 · EU 2025-522074-37-00
Phase 3Enrolling by invitation
A Study Evaluating the Long-Term Efficacy and Safety of Ralinepag in Subjects With PAH Via an Open-Label Extension
Where
Genoa, Palermo, Pavia, Rome
Age
18 years and over
People
1,000 worldwide
Run by
United Therapeutics
See details and how to joinNCT03683186 · EU 2023-509305-68-00
Phase 3Taking people
An Adaptive Program of IKT-001 in Pulmonary Arterial Hypertension (PAH)
Where
Milan, Monza, Pavia, Rome
Age
18 years to 75 years
People
486 worldwide
Run by
Inhibikase Therapeutics
See details and how to joinNCT07365332 · EU 2024-520218-23-00
Phase 1/2Taking people
A Study to Learn About the Treatment LTP001 in Healthy Participants (Part A) and in Participants With PAH (Part B)
Where
Foggia, Ivrea, Monza, Palermo, Pavia, Roma, Sassari, Trieste
Age
18 years to 100 years
People
232 worldwide
Run by
Novartis Pharmaceuticals
See details and how to joinNCT06649110
Phase 3Not yet taking people in Italy
A Phase 3 Study of Extended-release Tacrolimus in Subjects With Pulmonary Arterial Hypertension and Functional Limitations
Where
Pavia, Rome
Age
18 years to 75 years
People
300 worldwide
Run by
VIVUS LLC
See details and how to joinNCT07612657 · EU 2025-524596-24-00
No phaseTaking people
Prevalence, Pathogenesis, and Prognosis of Pulmonary Hypertension in Dialysis Patients
Where
Pavia
Age
18 years to 75 years
People
70
Run by
Fondazione IRCCS Policlinico San Matteo di Pavia
See details and how to joinNCT07563608
No phaseTaking people
COMPERA / COMPERA-KIDS
Where
Rome
Age
1 week and over
People
14,000 worldwide
Run by
Technische Universität Dresden
See details and how to joinNCT01347216
No phaseTaking people
PROOF OF CONCEPT STUDY ON THE EFFICACY OF INHALATORY TARGETED IMATINIB NANOFORMULATIONS IN PULMONARY HYPERTENSION AND POST-INFLAMMATORY FIBROSIS.
Where
Pavia
Age
18 years and over
People
16
Run by
Fondazione IRCCS Policlinico San Matteo di Pavia
See details and how to joinNCT06917196