Retinitis pigmentosa: open trials in United States

28 open trials have a site in United States. Registry data; only the trial team decides who can take part.

NCT02617966
Rod and Cone Mediated Function in Retinal Disease
Research · National Eye Institute (NEI)
National Institutes of Health Clinical Center, Bethesda
Registry updated 2026-11-05
NCT01432847
Cell Collection to Study Eye Diseases
Research · National Eye Institute (NEI)
National Institutes of Health Clinical Center, Bethesda
Registry updated 2026-11-04
NCT05589714
Universal Rare Gene Study: A Registry and Natural History Study of Retinal Dystrophies Associated With Rare Disease-Causing Genetic Variants
Research · Jaeb Center for Health Research
University of Michigan Kellogg Eye Center, Ann Arbor · Emory University, Emory Eye Center, Atlanta · Johns Hopkins University, Wilmer Eye Institute, Baltimore · Harvard Univ., Massachusetts Eye and Ear Infirmary, Boston · Retina Foundation of the Southwest, Dallas · Duke University, Duke Eye Center, Durham · Baylor College of Medicine, Alkek Eye Center, Houston · University of Florida Health Jacksonville, Jacksonville · University of Arkansas, Jones Eye Institute, Little Rock · USC Roski Eye Institute, Los Angeles · University of Wisconsin - Madison, Madison · University of Miami, Bascom Palmer Eye Institute, Miami · Medical College of Wisconsin Eye Institute, Milwaukee · University of Pennsylvania, Scheie Eye Institute, Philadelphia · UPMC Eye Center, Pittsburgh · Oregon Health & Science Univ., Casey Eye Institute, Portland · Mayo Clinic, Rochester · University of Utah, John Moran Eye Center, Salt Lake City · University of California San Francisco, San Francisco
Registry updated 2026-10-29
NCT01793168
Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford
Research · Sanford Health
Sanford Health, Sioux Falls
Registry updated 2026-10-28
NCT07901751
Study to Evaluate the Efficacy of a Single Intravitreal Injection of RTx-015 in Participants With Retinitis Pigmentosa (PERCEPT)
Trial Treatment · Phase 2/3 · Ray Therapeutics, Inc.
‘Aiea · Bakersfield · Beverly Hills · Bloomfield · Deerfield Beach · Detroit · Edina · Greensboro · Mt. Pleasant · Oak Park · Phoenix · Portland · San Antonio · Santa Barbara
Registry updated 2026-10-28
NCT05147701
Safety of Cultured Allogeneic Adult Umbilical Cord or Placental Derived Mesenchymal Stem Cell Exosomes for NAION
Trial Treatment · Phase 1 · The Foundation for Orthopaedics and Regenerative Medicine
Prodromos Stem Cell Institute, Naples
Registry updated 2026-10-16
NCT06789445
A Study to Investigate the Safety of OpCT-001 in Adults Who Have Primary Photoreceptor Disease (CLARICO)
Trial Treatment · Phase 1/2 · BlueRock Therapeutics
Retina Foundation of the Southwest, Dallas · University of Southern California /Children's Hospital of Los Angeles, Los Angeles · University of Wisconsin, Madison · University of Miami, Bascom Palmer Eye Institute, Miami · Mid Atlantic Retina/ Wills Eye, Philadelphia
Registry updated 2026-10-15
NCT07710196
A 24-Month Trial of NPI-001 for the Preservation of Photoreceptors in Retinitis Pigmentosa Associated With Usher Syndrome
Trial Treatment · Phase 3 · Nacuity Pharmaceuticals, Inc.
Retina Foundation of the Southwest, Dallas
Registry updated 2026-10-13
NCT06445322
Prescreening Study to Identify Potential Stargardt Participants for ACDN-01 Clinical Trials (STARPATH)
Research · Ascidian Therapeutics, Inc
University of Michigan Kellogg Eye Center, Ann Arbor · Wilmer Eye Institute at John Hopkins, Baltimore · Boston Children's Hospital, Boston · Massachusetts Eye and Ear, Boston · Cincinnati Eye Institute, Cincinnati · Retina Foundation of Texas, Dallas · Vitreo Retinal Associates, Gainesville · Retina Consultants of Texas, Houston · University of San Francisco, San Francisco
Registry updated 2026-10-09
NCT06467344
Study to Evaluate ACDN-01 in ABCA4-related Stargardt Retinopathy (STELLAR)
Trial Treatment · Phase 1/2 · Ascidian Therapeutics, Inc
University of Michigan Kellogg Eye Center, Ann Arbor · Wilmer Eye Institute at John Hopkins, Baltimore · Massachusetts Eye and Ear, Boston · Cincinnati Eye Institute, Cincinnati · Retina Foundation of the Southwest, Dallas · Vitreo Retinal Associates, Gainesville · Retina Consultants of Texas, Houston · Bascom Palmer Eye Institute, Miami · Children's Hospital of Philadelphia, Philadelphia · Casey Eye Institute - OHSU, Portland · University of San Francisco, San Francisco
Registry updated 2026-10-07
NCT07408232
A Phase 1/2 Study in Healthy Volunteers and Participants With Autosomal Dominant Retinitis Pigmentosa (RHO-adRP)
Trial Treatment · Phase 1/2 · Octant, Inc.
Retina Foundation of the Southwest, Dallas · Casey Eye Institute, Portland
Registry updated 2026-09-24
NCT06319872
The Effects of Disulfiram (Antabuse®) on Visual Acuity in Patients With Retinal Degeneration
Trial Treatment · Phase 1 · University of Rochester
Flaum Eye Institute, University of Rochester Medical Center, Rochester
Registry updated 2026-09-16
NCT06092346
A Natural History Study Seeks to Understand the Clinical, Genomic, Pharmacological, Laboratory, and Dietary Determinates of Pyrimidine and Purine Metabolism Disorders
Research · National Human Genome Research Institute (NHGRI)
National Institutes of Health Clinical Center, Bethesda
Registry updated 2026-08-19
NCT03011541
Stem Cell Ophthalmology Treatment Study II
Trial Treatment · MD Stem Cells
MD Stem Cells, Coral Springs · MD Stem Cells, Westport
Registry updated 2026-06-29
NCT00254605
Retinal Imaging in Patients With Inherited Retinal Degenerations
Research · University of California, San Francisco
Department of Ophthalmology Retinal Degenerations Clinic, UCSF, San Francisco
Registry updated 2026-06-05
NCT02435940
Inherited Retinal Degenerative Disease Registry
Research · Foundation Fighting Blindness
Foundation Fighting Blindness, Columbia
Registry updated 2026-05-19
NCT06565572
Antisense Oligonucleotide Treatment for PCARP Disease Due to Mutation in FLVCR1
Trial Treatment · Early phase 1 · University of Colorado, Denver
Childrens Hospital Colorado, Aurora
Registry updated 2026-05-19
NCT05355415
Adaptive Optics Imaging of Outer Retinal Diseases
Research · Food and Drug Administration (FDA)
NIH Clinical Center, Bethesda · Food and Drug Administration, Silver Spring
Registry updated 2026-05-08
NCT01866371
High Resolution Retinal Imaging
Research · University of Pennsylvania
University of Pennsylvania, Philadelphia
Registry updated 2026-05-05
NCT05626920
Disulfiram for Treatment of Retinal Degeneration
Trial Treatment · Phase 1/2 · University of Washington
University of Washington-South Lake Union Retina Center, Seattle
Registry updated 2026-05-05
NCT06891885
A Study to Investigate the Safety of DSP-3077 After a Unilateral Eye Injection in Male and Female Participants 18 Years of Age or Older With Retinitis Pigmentosa
Trial Treatment · Phase 1/2 · Sumitomo Pharma America, Inc.
Massachusetts Eye and Ear, Boston · University of Minnesota, Minneapolis
Registry updated 2026-04-17
NCT07502664
Development and Evaluation of Functional Visual Field and Navigation Endpoints in Moderate to Profound Inherited Retinal Disease (DEFINE-IRD)
Research · Ray Therapeutics, Inc.
Vision Research and Assessment Institute, Irvine
Registry updated 2026-03-31
NCT01694940
North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC)
Research · Columbia University
Akron Children's Hospital, Akron · Children's Hospital of Colorado, Aurora · Massachusetts General Hospital, Boston · Cleveland Clinic, Cleveland · Case Western Reserve University, Clevland · University of Florida, Gainsville · Baylor College of Medicine, Houston · Columbia University Medical Center, New York · Virtual Site (Remote enrollment), New York · The Children's Hospital Of Philadelphia, Philadelphia · Children's Hospital of Pittsburgh, Pittsburgh · Mayo Clinic, Rochester · University of California San Diego, San Diego · Seattle Children's Hospital and Regional Medical Center, Seattle · Lucile Packard Children's Hospital, Stanford · Children's National Medical Center, Washington D.C.
Registry updated 2026-02-04
NCT04278131
BS01 in Patients With Retinitis Pigmentosa
Trial Treatment · Phase 1/2 · Bionic Sight LLC
New Jersey Retina, Teaneck
Registry updated 2026-01-23
NCT05809635
Study of BEST1 Vitelliform Macular Dystrophy
Research · Columbia University
Columbia University Irving Medical Center, New York
Registry updated 2025-07-30

All Retinitis pigmentosa trials and the map

This page is not medical advice. Talk to your doctor before contacting a trial.

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