Sarcoma trials in Spain
37 of 40 trials · From ClinicalTrials.gov and EU CTIS (euclinicaltrials.eu), checked 11 November 2026. Ask the study team whether a trial fits you.
- Phase 3Taking peopleA Study of Calderasib (MK-1084) Plus Pembrolizumab (MK-3475) in Participants With KRAS G12C Mutant Non-small Cell Lung Cancer (NSCLC) With Programmed Cell Death Ligand 1 (PD-L1) Tumor Proportion Score (TPS) ≥50% (MK-1084-004/KANDLELIT-004)
- Where
- Barcelona, Las Palmas de Gran Canaria, Leganés, Madrid, Málaga, Sevilla, Vic
- Age
- 18 years and over
- People
- 348 worldwide
- Run by
- Merck Sharp & Dohme LLC
See details and how to joinNCT06345729 · EU 2023-507776-42-00 - Phase 2Taking peopleKEYMAKER-U01 Substudy 01J: A Study of Pembrolizumab Plus MK-1084 in Participants With Non-Small Cell Lung Cancer (NSCLC) With Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) G12C Mutations (MK-3475-01J/KEYMAKER-U01J)
- Where
- Pozuelo de Alarcón, Sevilla
- Age
- 18 years and over
- People
- 140 worldwide
- Run by
- Merck Sharp & Dohme LLC
See details and how to joinNCT07252739 · EU 2025-521939-36-00 - Phase 3Taking peopleA Study to Evaluate the Efficacy and Safety of Divarasib Compared With Investigator's Choice of Immunotherapy or Observation in Participants With Resected Stage II-III KRAS G12C-Positive Non-Small Cell Lung Cancer (NSCLC)
- Where
- A Coruña, Badalona, Barcelona, Bilbao, Granada, Lleida, Madrid, Majadahonda, Málaga, Palma, Reus, Sabadell, Santa Cruz de Tenerife, Sant Joan d'Alacant, Sevilla, Valencia, Zaragoza
- Age
- 18 years and over
- People
- 400 worldwide
- Run by
- Hoffmann-La Roche
See details and how to joinNCT07541170 · EU 2025-524263-21-01 - Phase 2Taking peopleA Study to Learn More About How Well Treatment With Sevabertinib (BAY 2927088) Tablets Works and How Safe it is in Participants Who Have a Solid Tumor With Mutations of the Human Epidermal Growth Factor Receptor 2 (HER2)
- Where
- Barcelona, L'Hospitalet de Llobregat, Madrid
- Age
- 18 years and over
- People
- 111 worldwide
- Run by
- Bayer
See details and how to joinNCT06760819 · EU 2024-517419-62-00 - Phase 2Taking peopleClinical Study in Adult and Young Adult Patients With Advanced Desmoplastic Small Round Cell Tumor (DSRCT) ISG-TULIPS
- Where
- Barcelona, Madrid, Sevilla, Zaragoza, HOSPITAL CLINICO UNIVERSITARIO VIRGEN DE LA ARRIXACA
- Age
- 15 years and over
- People
- 20 worldwide
- Run by
- Italian Sarcoma Group
See details and how to joinNCT07328425 · EU 2024-519261-21-00 - Phase 1/2Taking peopleSubstudy 01A: Zilovertamab Vedotin in Pediatric and Young Adult Participants With Hematologic Malignancies or Solid Tumors (MK-9999-01A/LIGHTBEAM-U01)
- Where
- Barcelona, Esplugues De Llobregat, Madrid, Valencia
- Age
- 6 months to 25 years
- People
- 90 worldwide
- Run by
- Merck Sharp & Dohme LLC
See details and how to joinNCT06395103 · EU 2023-507178-41-00 - Phase 1/2Taking peopleClinical trial of selinexor plus gemcitabine in selected advanced soft-tissue sarcomas
- Where
- Barcelona, Donostia, Madrid, Murcia, San Cristóbal de La Laguna, Valencia, Zaragoza
- Age
- 18 years and over
- People
- 88
- Run by
- Asociacion Europea Y Latinoamericana SELNET Para La Investigacion En Sarcomas
See details and how to join2024-520318-23-00 · EU 2024-520318-23-00 - Phase 1Taking peoplePhase I Trial to Determine the Dose and Evaluate the PK and Safety of Lutetium Lu 177 Edotreotide Therapy in Pediatric Participants With SSTR-positive Tumors
- Where
- Barcelona, Madrid
- Age
- 24 months to 18 years
- People
- 20 worldwide
- Run by
- ITM Solucin GmbH
See details and how to joinNCT06441331 · EU 2024-512831-66-00 - Phase 3Taking peopleFight Osteosarcoma Through European Research Evolving Study Platform From Diagnosis to Relapse
- Where
- Barakaldo, Barcelona, Madrid, Murcia, Santa Cruz de Tenerife, Seville, Valencia, Zaragoza
- Age
- 4 years and over
- People
- 530 worldwide
- Run by
- Gustave Roussy, Cancer Campus, Grand Paris
See details and how to joinNCT07871864 - Phase 3Taking peopleSurgery With or Without Neoadjuvant Chemotherapy in High Risk RetroPeritoneal Sarcoma
- Where
- Barcelona, Madrid
- Age
- 18 years and over
- People
- 250 worldwide
- Run by
- European Organisation for Research and Treatment of Cancer - EORTC
See details and how to joinNCT04031677 - Phase 1Taking peopleA Study to Evaluate the Safety, Tolerability, Pharmacokinetics (PK) and Preliminary Clinical Activity of RO7673396 in Participants With Advanced Solid Tumors Harboring Rat Sarcoma Viral Oncogene Homolog (RAS) Mutation(s)
- Where
- Barcelona, Madrid, Pamplona
- Age
- 18 years and over
- People
- 405 worldwide
- Run by
- Hoffmann-La Roche
See details and how to joinNCT06884618 · EU 2024-519622-20-00 - Phase 1/2Taking peopleA Study of Repotrectinib in Pediatric and Young Adult Subjects Harboring ALK, ROS1, OR NTRK1-3 Alterations
- Where
- Barcelona, Esplugues De Llobregat, Madrid, Pamplona, Sevilla, Valencia
- Age
- Up to 25 years
- People
- 75 worldwide
- Run by
- Turning Point Therapeutics, Inc.
See details and how to joinNCT04094610 · EU 2023-506464-14-00 - Phase 1/2Taking peopleA First-in-Human Trial of BLU-924 (SAR449336) in Advanced Solid Tumors Harboring KRAS Mutations
- Where
- Barcelona, Madrid, Pamplona, Pozuelo de Alarcón
- Age
- 18 years and over
- People
- 265 worldwide
- Run by
- Blueprint Medicines Corporation
See details and how to joinNCT07629960 - Phase 4Not yet taking people in SpainMulticentre, randomized, open label study comparing the concomitant administration of trabectedin and low-dose radiotherapy versus trabectedin alone in patients with advanced sarcoma
- Where
- Barcelona, Bilbao, Madrid, Oviedo, San Cristóbal de La Laguna, Sevilla, Valencia, Zaragoza
- Age
- 18 years and over
- People
- 80
- Run by
- Instituto De Investigacion Sanitaria Fundacion Jimenez Diaz
See details and how to join2026-525703-27-00 · EU 2026-525703-27-00 - Phase 1Taking peopleA phase I open-label, multi-center study to evaluate the safety, tolerability, dosimetry, and preliminary activity of [177Lu]Lu-DFC413 and safety and imaging properties of [68Ga]Ga-NNS309 in patients with solid tumors
- Where
- Barcelona, L'Hospitalet de Llobregat
- Age
- 18 years and over
- People
- 62 worldwide
- Run by
- Novartis Pharma AG
See details and how to join2025-521702-18-00 · EU 2025-521702-18-00 - Phase 1Taking peoplePhase 1 Study of INBRX-109 in Subjects With Locally Advanced or Metastatic Solid Tumors Including Sarcomas
- Where
- Barcelona, Madrid
- Age
- 12 years to 85 years
- People
- 411 worldwide
- Run by
- Inhibrx Biosciences, Inc
See details and how to joinNCT03715933 · EU 2023-508139-29-00 - Phase 1/2Taking peopleSafety and Tolerability of TNG462 in Patients With MTAP-deleted Solid Tumors
- Where
- Barcelona, Madrid, Málaga, Seville
- Age
- 18 years and over
- People
- 225 worldwide
- Run by
- Tango Therapeutics, Inc.
See details and how to joinNCT05732831 - Phase 1/2Taking peoplePhase I-II prospective trial, multicenter, open label, exploring the combination of Trabectedin plus RAdiotherapy in Soft Tissue Sarcoma patients
- Where
- Barcelona, Madrid, Palma, San Cristóbal de La Laguna, Sevilla, Zaragoza
- Age
- 18 years and over
- People
- 163 worldwide
- Run by
- Asoc Grupo Espanol De Investigacion En Sarcomas
See details and how to join2024-518199-30-00 · EU 2024-518199-30-00 - Phase 1/2Taking peopleA Phase Ib/II Study to Evaluate Safety and Efficacy of Bexmarilimab in Combination With Doxorubicin in Metastatic Soft-tissue Sarcoma.
- Where
- Badalona, Barcelona, Madrid, Málaga, San Cristóbal de La Laguna, Sevilla, Valencia, Zaragoza
- Age
- 18 years to 64 years
- People
- 278
- Run by
- MedSIR
See details and how to joinNCT07460986 · EU 2025-525144-18-00 - Phase 1Taking peopleLong-Term Follow-Up (LTFU) of Participants Treated with Adoptive Cell Therapies
- Where
- Sevilla
- People
- 7 worldwide
- Run by
- USWM Ct LLC
See details and how to join2024-513033-21-00 · EU 2024-513033-21-00 - Phase 3Taking peopleA Study to Investigate Efficacy & Safety of Intratumoral INT230-6 Compared to US Standard of Care in Adults With Soft Tissue Sarcomas (INVINCIBLE-3)
- Where
- Barcelona, Granada, L'Hospitalet de Llobregat, Madrid, Pamplona, Sevilla, Valencia
- Age
- 18 years and over
- People
- 333 worldwide
- Run by
- Intensity Therapeutics, Inc.
See details and how to joinNCT06263231 · EU 2024-512423-36-00 - Phase 1Taking peopleTrial to evaluate CAR-T NKG2D CAR cell infusions in patients with advanced sarcoma
- Where
- Madrid
- Age
- Up to 64 years
- People
- 18
- Run by
- Hospital Universitario La Paz
See details and how to join2024-513514-35-00 · EU 2024-513514-35-00 - Phase 2Taking peopleClinical trial of trabectedin, irinotecann and low-dose radiation therapy in advanced/metastatic sarcomas.
- Where
- Barcelona, La Laguna, Madrid, Valencia
- People
- 92
- Run by
- Asoc Grupo Espanol De Investigacion En Sarcomas
See details and how to joinNCT05131386 · EU 2023-509215-81-00 - Phase 1/2Taking peopleStudy in Children and Adolescents of 177Lu-DOTATATE (Lutathera®) Combined With the PARP Inhibitor Olaparib for the Treatment of Recurrent or Relapsed Solid Tumours Expressing Somatostatin Receptor (SSTR) (LuPARPed).
- Where
- Boadilla del Monte
- Age
- 3 years and over
- People
- 25
- Run by
- Fundación de investigación HM
See details and how to joinNCT06607692 · EU 2024-512613-40-00 - Phase 1/2Taking peopleA Study to Evaluate the Safety, Tolerability, and Efficacy of BMS-986523 Alone and in Combination With Anti-Cancer Agents in Participants With Advanced Solid Malignancies
- Where
- Badalona, Hortaleza
- Age
- 18 years and over
- People
- 252 worldwide
- Run by
- Bristol-Myers Squibb
See details and how to joinNCT07223047