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Sarcoma: open trials in United States

301 open trials have a site in United States. Registry data; only the trial team decides who can take part.

  • NCT06436612

    Study of Magnetic Resonance Image and Computed Tomography-Guided Stereotactic Body Radiation Therapy for Abdominopelvic Sarcomas (MARS Trial)

    Trial Treatment · Phase 2 · Jonsson Comprehensive Cancer Center

    UCLA / Jonsson Comprehensive Cancer Center, Los Angeles

    Registry updated 2026-06-05

  • NCT06957431

    Zanzalintinib Combined With Eribulin in Advanced Liposarcoma and Leiomyosarcoma

    Trial Treatment · Phase 1 · Washington University School of Medicine

    Washington University School of Medicine, St Louis

    Registry updated 2026-06-03

  • NCT03823144

    Intravital Microscopy in Human Solid Tumors

    Trial Treatment · Mayo Clinic

    Mayo Clinic Florida, Jacksonville

    Registry updated 2026-06-02

  • NCT05663502

    Collecting Blood and Tissue Sample Donations for Research for HIV/AIDS-Related Cancers

    Research · AIDS Malignancy Consortium

    Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore · UC San Diego Moores Cancer Center, La Jolla · University of Miami, Miami · Mount Sinai Hospital, New York · Memorial Sloan-Kettering Cancer Center, New York · Huntsman Cancer Institute/University of Utah, Salt Lake City · University of California San Francisco, San Francisco · George Washington University, Washington D.C.

    Registry updated 2026-06-01

  • NCT07223047

    A Study to Evaluate the Safety, Tolerability, and Efficacy of BMS-986523 Alone and in Combination With Anti-Cancer Agents in Participants With Advanced Solid Malignancies

    Trial Treatment · Phase 1/2 · Bristol-Myers Squibb

    Johns Hopkins Hospital, Baltimore · NEXT Virginia, Fairfax · NEXT Oncology, San Antonio · START Mountain Region, West Valley City

    Registry updated 2026-05-28

  • NCT03093116

    A Study of Repotrectinib (TPX-0005) in Patients With Advanced Solid Tumors Harboring ALK, ROS1, or NTRK1-3 Rearrangements

    Trial Treatment · Phase 1/2 · Turning Point Therapeutics, Inc.

    Ann Arbor · Appleton · University Cancer and Blood Center, Athens · Aurora · Aurora · Baltimore · Bolivar · Boston · Massachusetts General Hospital, Boston · Boston · Canton · University of Chicago, Chicago · Cincinnati · Cleveland · Columbus · The Ohio State University -Wexner Medical Center, Columbus · UT Southwestern Medical Center, Dallas · Detroit · Detroit · Duarte · Fairfax · Glendale · Goldsboro · Memorial Healthcare System, Hollywood · Houston · MD Anderson Cancer Center, Houston · Kingwood · La Jolla · La Jolla · Long Beach · Baptist Memorial Hospital Baptist Cancer Center, Memphis · New Brunswick · New Orleans · New York · New York · New York · Orange · Orange · Peoria · Philadelphia · Saint Paul · St Joseph Heritage Healthcare, Santa Rosa · Seattle · Washington University Infusion Center Pharmacy, St Louis · Tacoma · Tampa · Toledo · Washington D.C. · Washington D.C.

    Registry updated 2026-05-27

  • NCT03589729

    Dexrazoxane Hydrochloride in Preventing Heart-Related Side Effects of Chemotherapy in Participants With Blood Cancers

    Trial Treatment · Phase 2 · M.D. Anderson Cancer Center

    M D Anderson Cancer Center, Houston

    Registry updated 2026-05-22

  • NCT06113809

    Palbociclib and Pembrolizumab in Sarcoma

    Trial Treatment · Phase 1 · John Rieth

    University of Iowa Hospitals & Clinics, Iowa City

    Registry updated 2026-05-22

  • NCT07049848

    Registry updated 2026-05-22

  • NCT07467772

    Ph 2 Elacestrant in ER Positive Uterine Sarcomas

    Trial Treatment · Phase 2 · Dana-Farber Cancer Institute

    Dana-Farber Cancer Institute, Boston

    Registry updated 2026-05-22

  • NCT05054335

    Registry updated 2026-05-20

  • NCT04897321

    B7-H3-Specific Chimeric Antigen Receptor Autologous T-Cell Therapy for Pediatric Patients With Solid Tumors (3CAR)

    Trial Treatment · Phase 1 · St. Jude Children's Research Hospital

    St. Jude Children's Research Hospital, Memphis

    Registry updated 2026-05-19

  • NCT04901702

    Study of Onivyde With Talazoparib or Temozolomide in Children With Recurrent Solid Tumors and Ewing Sarcoma

    Trial Treatment · Phase 1/2 · St. Jude Children's Research Hospital

    Children's Healthcare of Atlanta/Emory University School of Medicine, Atlanta · Children's Hospital Colorado, Aurora · Texas Children's Hospital/ Baylor College of Medicine, Houston · St. Jude Children's Research Hospital, Memphis · Children's Hospital and Clinics of Minn, Minneapolis · Lucille Packard Children's Hospital Stanford, Palo Alto · Children's National Medical Center, Washington D.C.

    Registry updated 2026-05-19

  • NCT01790152

    Effects of Dexrazoxane Hydrochloride on Biomarkers Associated With Cardiomyopathy and Heart Failure After Cancer Treatment

    Research · Children's Oncology Group

    Children's Hospital Medical Center of Akron, Akron · University of New Mexico Cancer Center, Albuquerque · Mission Hospital, Asheville · Children's Healthcare of Atlanta-Egleston, Atlanta · Sinai Hospital of Baltimore, Baltimore · Johns Hopkins University/Sidney Kimmel Cancer Center, Baltimore · Children's Hospital of Alabama, Birmingham · Dana-Farber Cancer Institute, Boston · Roswell Park Cancer Institute, Buffalo · University of Vermont and State Agricultural College, Burlington · Medical University of South Carolina, Charleston · University of Illinois, Chicago · Lurie Children's Hospital-Chicago, Chicago · Cincinnati Children's Hospital Medical Center, Cincinnati · Columbia Regional, Columbia · UT Southwestern/Simmons Cancer Center-Dallas, Dallas · Medical City Dallas Hospital, Dallas · Ascension Saint John Hospital, Detroit · Wayne State University/Karmanos Cancer Institute, Detroit · City of Hope Comprehensive Cancer Center, Duarte · Hurley Medical Center, Flint · Golisano Children's Hospital of Southwest Florida, Fort Myers · Cook Children's Medical Center, Fort Worth · University of Florida Health Science Center - Gainesville, Gainesville · BI-LO Charities Children's Cancer Center, Greenville · Hackensack University Medical Center, Hackensack · Memorial Regional Hospital/Joe DiMaggio Children's Hospital, Hollywood · Kapiolani Medical Center for Women and Children, Honolulu · University of Hawaii Cancer Center, Honolulu · Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center, Houston · University of Mississippi Medical Center, Jackson · Nemours Children's Clinic-Jacksonville, Jacksonville · Sunrise Hospital and Medical Center, Las Vegas · University Medical Center of Southern Nevada, Las Vegas · Summerlin Hospital Medical Center, Las Vegas · Alliance for Childhood Diseases/Cure 4 the Kids Foundation, Las Vegas · Dartmouth Hitchcock Medical Center, Lebanon · Arkansas Children's Hospital, Little Rock · Valley Children's Hospital, Madera · Children's Hospital of Wisconsin, Milwaukee · Yale University, New Haven · The Steven and Alexandra Cohen Children's Medical Center of New York, New Hyde Park · Ochsner Medical Center Jefferson, New Orleans · Kaiser Permanente-Oakland, Oakland · Advocate Children's Hospital-Oak Lawn, Oak Lawn · University of Oklahoma Health Sciences Center, Oklahoma City · Nemours Children's Hospital, Orlando · Lucile Packard Children's Hospital Stanford University, Palo Alto · Saint Jude Midwest Affiliate, Peoria · Saint Christopher's Hospital for Children, Philadelphia · Phoenix Childrens Hospital, Phoenix · Legacy Emanuel Children's Hospital, Portland · Oregon Health and Science University, Portland · Rhode Island Hospital, Providence · Virginia Commonwealth University/Massey Cancer Center, Richmond · University of Rochester, Rochester · University of Texas Health Science Center at San Antonio, San Antonio · Rady Children's Hospital - San Diego, San Diego · Maine Children's Cancer Program, Scarborough · Seattle Children's Hospital, Seattle · Providence Sacred Heart Medical Center and Children's Hospital, Spokane · Washington University School of Medicine, St Louis · Stony Brook University Medical Center, Stony Brook · Johns Hopkins All Children's Hospital, St. Petersburg · State University of New York Upstate Medical University, Syracuse · Saint Joseph's Hospital/Children's Hospital-Tampa, Tampa · Banner University Medical Center - Tucson, Tucson · Saint Mary's Hospital, West Palm Beach · Wake Forest University Health Sciences, Winston-Salem

    Registry updated 2026-05-18

  • NCT06129903

    Study Assessing the Effects of Early Psychiatric Referral on Mental Health and Quality of Life in People With Sarcoma

    Trial Treatment · Memorial Sloan Kettering Cancer Center

    Memorial Sloan Kettering at Basking Ridge (Limited Protocol Activities), Basking Ridge · Memorial Sloan Kettering Suffolk - Commack (Limited Protocol Activities), Commack · William Beaumont Army Medical Center, Fort Bliss · Memorial Sloan Kettering Westchester (All Protocol Activities), Harrison · Memorial Sloan Kettering Monmouth (All Protocol Activities), Middletown · Memorial Sloan Kettering Bergen (Limited Protocol Activities), Montvale · Memorial Sloan Kettering Cancer Center (All Protocol Activites), New York · Memorial Sloan Kettering Nassau (All Protocol Activities), Uniondale

    Registry updated 2026-05-15

  • NCT06892678

    DFMO Maintenance for Patients With Relapsed/Refractory Ewing Sarcoma or Osteosarcoma

    Trial Treatment · Phase 1/2 · Montefiore Medical Center

    Montefiore Medical Center, The Bronx

    Registry updated 2026-05-14

  • NCT06064682

    An Organoid-based Functional Precision Medicine Trial in Osteosarcoma

    Research · Jonsson Comprehensive Cancer Center

    UCLA / Jonsson Comprehensive Cancer Center, Los Angeles

    Registry updated 2026-05-11

  • NCT06500819

    Autologous B7-H3 Chimeric Antigen Receptor T Cells in Relapsed/Refractory Solid Tumors

    Trial Treatment · Phase 1 · Stanford University

    Stanford University, Palo Alto

    Registry updated 2026-05-07

  • NCT01042379

    I-SPY TRIAL: Neoadjuvant and Personalized Adaptive Novel Agents to Treat Breast Cancer

    Trial Treatment · Phase 2 · QuantumLeap Healthcare Collaborative

    Winship Cancer Institute of Emory University, Atlanta · University of Colorado Cancer Center, Aurora · University of Alabama at Birmingham, Birmingham · Roswell Park Cancer Institute, Buffalo · University of Chicago, Chicago · Cleveland Clinic, Cleveland · The Ohio State University, Stefanie Spielman Comprehensive Breast Center, Columbus · University of Texas Southwestern Medical Center, Dallas · University of California - Davis, Comprehensive Cancer Center, Davis · City of Hope, Duarte · Inova Health System, Falls Church · University of Texas M.D. Anderson Cancer Center, Houston · University of California San Diego, La Jolla · Herbert-Herman Cancer Center, Sparrow Hospital, Lansing · University of Southern California, Los Angeles · Loyola University, Maywood · University of Minnesota, Minneapolis · Vanderbilt University Medical Center, Nashville · Rutgers Cancer Institute of New Jersey, New Brunswick · Yale Cancer Center, New Haven · Hoag Memorial Hospital Presbyterian, Newport Beach · Laura and Isaac Perlmutter Cancer Center/ NYU Langone Health, New York · Columbia University Medical Center, New York · University of Pennsylvania (U Penn), Philadelphia · University Pittsburgh Medical Center, Pittsburgh · Oregon Health & Science Institute (OHSU), Portland · University of Rochester Wilmot Cancer Institute, Rochester · Mayo Clinic, Rochester · Metro Minnesota Community Oncology Research Consortium, Hennepin County Medical Center, Saint Louis Park · Huntsman Cancer Institute/University of Utah, Salt Lake City · University of California, San Francisco (UCSF), San Francisco · Mayo Clinic Scottsdale, Scottsdale · Swedish Cancer Institute, Seattle · University of Washington, Seattle · Sanford Clinical Research, Sioux Falls · Moffitt Cancer Center, Tampa · H Lee Moffitt Cancer Center and Research Institute, Tampa · Montefiore Medical Center, The Bronx · University of Arizona, Tucson · Georgetown University Medical Center, Washington D.C. · University of Kansas, Westwood · Wake Forest Baptist Comprehensive Cancer Center, Winston-Salem

    Registry updated 2026-05-06

  • NCT06132503

    Safety, Pharmacokinetics, and Clinical Activity of LP-284 in Adult Patients With Relapsed or Refractory Lymphomas and Solid Tumors

    Trial Treatment · Phase 1 · Lantern Pharma Inc.

    START Mountain Region, West Valley City

    Registry updated 2026-05-04

  • NCT07357519

    Lu-TARGO (177Lu-TARGeted Osteosarcoma Therapy)

    Trial Treatment · Phase 1/2 · Lantheus Medical Imaging

    Dana-Farber Cancer Institute, Boston · UCLA, Los Angeles

    Registry updated 2026-05-01

  • NCT05297734

    Comparative Effectiveness Trial of Two Supportive Cancer Care Delivery Models for Adults With Cancer

    Trial Treatment · Stanford University

    University of Alabama at Birmingham, Birmingham · Beckman Research Institute of City of Hope, Duarte · VA Medical Center, Fresno, Fresno · Santa Clara Valley Medical Center, Fruitdale · St Jude Heritage Medical Group, Fullerton · Spark M. Matsunaga VA Medical Center, Honolulu · North Las Vegas VA Medical Center, Las Vegas · Oncology Institute for Hope and Innovation, Los Angeles · Sacramento VA Medical Center - VA Northern California Health Care System, Mather · University of South Alabama, Mobile · Pacific Cancer Care, Monterey · VA Palo Alto, Palo Alto · George E. Wahlen Department of Veterans Affairs Medical Center, Salt Lake City · University of San Francisco, San Francisco · Zuckerberg San Francisco General, San Francisco · Kaiser Foundation Research Institute, San Francisco · San Francisco VA Medical Center, San Francisco

    Registry updated 2026-04-30

  • NCT04332874

    A Study of Pembrolizumab Plus Local Chemotherapy Using Isolated Limb Infusion (ILI) for Patients With Sarcoma in the Arm or Leg

    Trial Treatment · Phase 2 · Memorial Sloan Kettering Cancer Center

    Memorial Sloan Kettering Basking Ridge (Limited Protocol Activities), Basking Ridge · Memorial Sloan Kettering Cancer Center @ Suffolk-Commack (Limited Protocol Activities), Commack · Memorial Sloan Kettering Westchester (Limited Protocol Activities), Harrison · Memorial Sloan Kettering Monmouth (Limited Protocol Activities), Middletown · Memorial Sloan Kettering Bergen (Limited Protocol Activities), Montvale · Memorial Sloan-Kettering Cancer Center, New York · Memorial Sloan Kettering Nassau (Limited Protocol Activities), Uniondale

    Registry updated 2026-04-23

  • NCT03442465

    Assessment of Healing and Function After Reconstruction Surgery for Bone Sarcomas

    Research · Memorial Sloan Kettering Cancer Center

    Memorial Sloan Kettering at Basking Ridge (Consent and Follow Up), Basking Ridge · Memorial Sloan Kettering Westchester (Consent and Followup), Harrison · Memorial Sloan Kettering Monmouth (Consent and Followup), Middletown · Memorial Sloan-Kettering Cancer Center, New York · Memorial Sloan Kettering at Nassau (Consent and Followup), Uniondale

    Registry updated 2026-04-17

  • NCT05917301

    Pre-operative Hypofractionated Proton Therapy

    Trial Treatment · Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

    Sibley Memorial Hospital, Washington D.C.

    Registry updated 2026-04-17

All Sarcoma trials and the map

This page is not medical advice. Talk to your doctor before contacting a trial.