Sarcoma: open trials in United States

• NCT07064018

  Trial of Single Protein Encapsulated Doxorubicin, SPEDOX-6 in Advanced Malignancies

  Trial Treatment · Phase 1/2 · University of California, Irvine

  Chao Family Comprehensive Cancer Center, University of California, Irvine, Orange

  Registry updated 2026-07-17

• NCT03093909

  Study of Aerosol Gemcitabine in Patients With Solid Tumors and Pulmonary Metastases

  Trial Treatment · Phase 1 · M.D. Anderson Cancer Center

  The University of Texas MD Anderson Cancer Center, Houston

  Registry updated 2026-07-15

• NCT03261544

  Abductor Reattachment Methods in Proximal Femur Replacements: What is the Best Method?

  Research · Duke University

  Duke University, Durham

  Registry updated 2026-07-15

• NCT07377747

  Prospective Study Evaluating the Treatment Outcomes for Localised Recurrent, Resectable Retroperitoneal Liposarcoma

  Research · Australia and New Zealand Sarcoma Association

  Emory Winship Cancer Institute, Atlanta · Brigham and Women's Hospital, Boston · OSU James Hospital, Columbus · MD Anderson Cancer Center, Houston

  Registry updated 2026-07-15

• NCT07389525

  Immune Checkpoint Inhibitor (ICI)-Drug-Drug Interaction (DDI) Study

  Trial Treatment · Early phase 1 · Indiana University

  Indiana University Melvin and Bren Simon Comprehensive Cancer Center, Indianapolis

  Registry updated 2026-07-15

• NCT06580002

  Repurposing Riluzole for Cancer-Related Cognitive Impairment: A Pilot Trial

  Trial Treatment · Phase 2 · University of California, Irvine

  Chao Family Comprehensive Cancer Center, University of California, Irvine, Orange

  Registry updated 2026-07-14

• NCT05000294

  Atezolizumab Plus Tivozanib in Immunologically Cold Tumor Types

  Trial Treatment · Phase 1/2 · University of Florida

  University of Florida, Gainesville

  Registry updated 2026-07-13

• NCT06796543

  Targeted Oligometastatic Radiation in Pediatric and Young Adult Patients With Soft Tissue and Bone Sarcoma

  Trial Treatment · Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

  Johns Hopkins Hospital, Baltimore · University of Minnesota, Minneapolis · Sibley Memorial Hospital, Washington D.C.

  Registry updated 2026-07-13

• NCT06103669

  Locally ablatiVe therApy in oLigO-pRogressive sOlid tUmorS (VALOROUS)

  Trial Treatment · University of California, Davis

  University of California - Davis, Sacramento

  Registry updated 2026-07-08

• NCT06327477

  Proton-Spatially Fractionated Radiotherapy and Standard Radiation Therapy for the Treatment of Newly Diagnosed Retroperitoneal Soft Tissue Sarcoma

  Trial Treatment · Phase 1/2 · Northwestern University

  Northwestern University, Chicago

  Registry updated 2026-07-07

• NCT07406087

  Navigation Intervention for Adolescent and Young Adult Cancer Survivors

  Trial Treatment · Kaiser Permanente

  KP Southern California - Department of Research & Evaluation, Pasadena

  Registry updated 2026-07-06

• NCT04925089

  Localized Leiomyosarcoma Biomarker Protocol

  Research · University of Michigan Rogel Cancer Center

  University of Michigan, Ann Arbor · Vanderbilt University Medical Center, Nashville · Mayo Clinic, Rochester

  Registry updated 2026-07-02

• NCT06625190

  Alpha/Beta T and B Cell Depletion With Zoledronic Acid for Solid Tumors

  Trial Treatment · Phase 1/2 · University of Florida

  University of Florida, Gainesville

  Registry updated 2026-06-30

• NCT07675967

  Clonal Hematopoiesis Chemotherapy and Radiation Effects Study

  Research · Dana-Farber Cancer Institute

  Dana-Farber Cancer Institute, Boston

  Registry updated 2026-06-30

• NCT02012699

  Integrated Cancer Repository for Cancer Research

  Research · University of Nebraska

  Riverwood Healthcare Center, Aitkin · Aultman Alliance Community Hospital, Alliance · Rush-Copley Cancer Care Center, Aurora · Bozeman Health Deaconess Hospital, Bozeman · Essentia Health-St. Joseph's Medical Center, Brainerd · Aultman Hospital, Canton · Methodist Jennie Edmundson Hospital, Council Bluffs · Florida Hospital Memorial Medical Center, Daytona Beach · Florida Hospital DeLand, DeLand · Essentia Health - Duluth Clinic, Duluth · St. Luke's Hospital of Duluth, Duluth · Essentia Health, Fargo · Cape Fear Valley Health System, Fayetteville · Lake Region Healthcare, Fergus Falls · Parkview Research Center, Fort Wayne · C.R. Wood Cancer Center, Glens Falls Hospital, Glens Falls · Bellin Memorial Hospital, Green Bay · Advent Health, Greenwood Village · Mary Lanning Healthcare, Morrison Cancer Center, Hastings · Holyoke Medical Center, Holyoke · Saint Luke's Cancer Institute, Kansas City · Saint Luke's Cancer Institute, East, Kansas City · Saint Luke's Cancer Institute, Kansas City North, Kansas City · Saint Luke's Cancer Institute, Liberty, Liberty · Hartford HealthCare Cancer Institute at Manchester Medical Hospital, Manchester · Trinity Hospital Cancer Care Center, Minot · Faith Regional Health Services Carson Cancer Center, Norfolk · North Kansas City Hospital, North Kansas City · Great Plains Regional Medical Center, North Platte · Methodist Estabrook Cancer Center, Omaha · University of Nebraska Medical Center, Omaha · Nebraska Methodist Health System, Omaha · Florida Hospital FISH, Orange City · Saint Luke's Cancer Instititute - South, Overland Park · Florida Hospital Flagler, Palm Coast · Northwest Hospital, Randallstown · Heartland Regional Medical Center dba Mosaic Life Care, Saint Joseph · Tallahassee Memorial Hospital, Tallahassee · Faxton St. Luke's Healthcare, Mohawk Valley, Utica · Covenant Medical Center, Inc, Waterloo · William E. Kahlert Regional Cancer Center, Westminster · Rush-Copley Healthcare Center, Yorkville

  Registry updated 2026-06-29

• NCT05653388

  Metastatic Leiomyosarcoma Biomarker Protocol

  Research · University of Michigan Rogel Cancer Center

  University of Michigan Cancer Center, Ann Arbor · Dana Farber, Boston · Ohio State University, Columbus · MD Anderson, Houston · University of Miami, Miami · Vanderbilt University Medical Center, Nashville · Memorial Sloan-Kettering Cancer Center, New York · Mayo Clinic, Rochester · Sarcoma Oncology Research Center, Santa Monica

  Registry updated 2026-06-24

• NCT05526417

  Individualized Prehabilitation for Enhancing Recovery and Surgical Outcomes in Patients Undergoing Radiotherapy and Surgery for Soft Tissue Sarcoma

  Trial Treatment · Mayo Clinic

  Mayo Clinic in Arizona, Scottsdale

  Registry updated 2026-06-22

• NCT07502885

  Deep Phenotyping Gait Deficits in Orthopedic Manifestations of Pediatric Cancer Patients

  Research · St. Jude Children's Research Hospital

  St. Jude Children's Research Hospital, Memphis

  Registry updated 2026-06-18

• NCT03050268

  Familial Investigations of Childhood Cancer Predisposition

  Research · St. Jude Children's Research Hospital

  St. Jude Children's Research Hospital, Memphis

  Registry updated 2026-06-17

• NCT06023641

  Treatment of Newly Diagnosed Rhabdomyosarcoma Using Molecular Risk Stratification and Liposomal Irinotecan Based Therapy in Children With Intermediate and High Risk Disease

  Trial Treatment · Phase 2 · St. Jude Children's Research Hospital

  Cook Children's Medical Center, Fort Worth · St. Jude Children's Research Hospital, Memphis · Stanford University, Palo Alto

  Registry updated 2026-06-15

• NCT04771520

  Avapritinib for the Treatment of CKIT or PDGFRA Mutation-Positive Locally Advanced or Metastatic Malignant Solid Tumors

  Trial Treatment · Phase 2 · M.D. Anderson Cancer Center

  M D Anderson Cancer Center, Houston

  Registry updated 2026-06-11

• NCT06789172

  A Phase 1, First-in-human Study of OKN4395 and Pembrolizumab in Patients With Solid Tumors

  Trial Treatment · Phase 1 · Epkin

  Precision NextGen Oncology and Research Center, Beverly Hills · MD Anderson Cancer Center, Houston · Sarcoma Oncology Center, Santa Monica

  Registry updated 2026-06-11

• NCT06087861

  5-Day Preoperative Radiation for Soft Tissue Sarcoma

  Trial Treatment · Phase 2 · Stanford University

  Stanford University, Palo Alto

  Registry updated 2026-06-10

• NCT05910307

  Synovial Sarcoma Registry / Biospecimen Repository

  Research · Children's Hospital of Philadelphia

  Children's Hospital of Philadelphia, Philadelphia

  Registry updated 2026-06-09

• NCT06235125

  Safety and Feasibility of Intraoperative Visualization With Cytalux in Children

  Trial Treatment · Phase 1 · Ann & Robert H Lurie Children's Hospital of Chicago

  Ann & Robert H. Lurie Children's Hospital, Chicago

  Registry updated 2026-06-05

All Sarcoma trials and the map

This page is not medical advice. Talk to your doctor before contacting a trial.

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