Schizophrenia trials in United States

In United States 179 Also abroad 473

179 trials · From ClinicalTrials.gov, checked 11 November 2026. Ask the study team whether a trial fits you.

No phaseTaking people
Developing a Recovery-Oriented Suicide Prevention Program for Young People at Clinical High Risk for Psychosis
Where
Los Angeles, San Diego
Age
12 years to 30 years
People
108
Run by
University of California, San Diego
See details and how to joinNCT07756567
No phaseTaking people
The Effects of Auditory Stimulation During Sleep on Brain Networks in Schizophrenia
Where
Charlestown
Age
18 years to 45 years
People
60
Run by
Massachusetts General Hospital
See details and how to joinNCT06386588
Phase 2Taking people
A Long-Term Open-Label Study of ML-007C-MA in Adults With Schizophrenia
Where
Ann Arbor, Atlanta, Austin, Bellflower, Boston, Cedarhurst, Cerritos, Chicago, Culver City, Decatur, DeSoto, Flowood, Gaithersburg, Garden Grove, Hollywood, Houston, Las Vegas, Lemon Grove, Little Rock, Long Beach, Los Angeles, Marlton, Miami, Miami Lakes, Montclair, New York, North Canton, Oceanside, Orange, Philadelphia, Pico Rivera, Richardson, Riverside, Rogers, San Diego, Sherman Oaks, Staten Island, The Bronx, Torrance, Watertown, West Chester, West Palm Beach
Age
18 years to 65 years
People
500
Run by
MapLight Therapeutics
See details and how to joinNCT07459647
No phaseEnrolling by invitation
Evaluation of Step-Based Care for Individuals at Clinical High Risk for Psychosis
Where
Columbus
Age
12 years to 25 years
People
100
Run by
Ohio State University
See details and how to joinNCT03970005
No phaseNot yet taking people in United States
DecNef for Auditory Verbal Hallucinations (AVH) in Schizophrenia
Where
New York
Age
18 years to 55 years
People
51
Run by
Columbia University
See details and how to joinNCT07779226
No phaseNot yet taking people in United States
Mobile Thinking Intervention: A Inital Test
Where
Birmingham
Age
18 years to 65 years
People
100
Run by
University of Alabama at Birmingham
See details and how to joinNCT06909422
No phaseNot yet taking people in United States
Online Intervention To Improve Motivation
Where
Birmingham
Age
18 years to 65 years
People
60
Run by
University of Alabama at Birmingham
See details and how to joinNCT07157293
No phaseTaking people
Targeting Emotion Dysregulation to Reduce Suicide in People With Psychosis
Where
Baltimore
Age
18 years and over
People
68
Run by
University of Maryland, Baltimore
See details and how to joinNCT05440214
No phaseNot yet taking people in United States
Feasibility Trial of a Parent Peer-Co-Led Caregiver Group for Pediatric Early Onset Schizophrenia Spectrum Disorders
Where
Brookline
Age
18 years and over
People
20
Run by
Boston Children's Hospital
See details and how to joinNCT07867964
No phaseTaking people
iTBS to Enhance Social Cognition in People With Psychosis
Where
Glen Oaks
Age
18 years to 39 years
People
100
Run by
Northwell Health
See details and how to joinNCT06118268
No phaseNot yet taking people in United States
Gamma Light and Sound Stimulation in Schizophrenia
Where
Cambridge
Age
18 years to 65 years
People
20
Run by
Massachusetts Institute of Technology
See details and how to joinNCT07342465
Phase 2Taking people
A Study of Brenipatide in Adult Participants With Schizophrenia
Where
Atlanta, Augusta, Bellevue, Bellflower, Belmont, Chicago, Cooper City, DeSoto, Eugene, Fort Worth, Gaithersburg, Garden Grove, Hartford, Hollywood, Independence, Lauderhill, Little Rock, Maitland, Miami, Montclair, Naples, New Haven, New York, Orlando, Philadelphia, Stanford, St Louis, Torrance, Walnut Creek, Watertown, Worcester
Age
18 years to 55 years
People
450 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT07410507
Phase 3Taking people
A Study to Evaluate the Efficacy and Safety of KarXT for the Treatment of Schizophrenia in Adolescents (EMERGENT TEEN)
Where
Anaheim, Atlanta, Boston, Chicago, Chino, Cincinnati, Culver City, Garland, Great Neck, Hollywood, Houston, Lawrenceville, Nashville, Orlando, Richmond, San Francisco, Spring, Stone Mountain, Worcester
Age
13 years to 17 years
People
166 worldwide
Run by
Bristol-Myers Squibb
See details and how to joinNCT07288567 · EU 2025-523711-11-00
No phaseNot yet taking people in United States
Pilot Study of Sensor-Informed Smartphone-based Mental Health Interventions for Mood in Early Psychosis
Where
Belmont
Age
18 years to 50 years
People
10
Run by
Mclean Hospital
See details and how to joinNCT07503093
No phaseTaking people
Acceptability and Feasibility of Work-Oriented Social-Cognitive Skills Training for Veterans With Serious Mental Illness
Where
Minneapolis
Age
18 years and over
People
20
Run by
VA Office of Research and Development
See details and how to joinNCT05491538
Phase 4Taking people
Safety and Tolerability of Open-Labeled Iloperidone in Adolescents
Where
Atlanta, Cincinnati, Decatur, Denver, Dothan, Everett, Garfield Heights, Kinston, Little Rock, Westlake
Age
12 years to 17 years
People
100
Run by
Vanda Pharmaceuticals
See details and how to joinNCT05648591
No phaseTaking people
Overnight Thalamic TES-TI to Modulate Sleep Spindles in Individuals With Schizophrenia Spectrum Disorders and Matched Healthy Controls
Where
Madison
Age
18 years to 50 years
People
20
Run by
University of Wisconsin, Madison
See details and how to joinNCT07680114
No phaseTaking people
Volatility in Paranoia (VIP) Trial: An RCT of Changes in Volatility With Psychotherapy
Where
Nashville
Age
18 years to 65 years
People
120
Run by
Vanderbilt University Medical Center
See details and how to joinNCT06835556
Phase 2Taking people
A Study to Assess the Efficacy and Safety of ML-007C-MA for the Treatment of Alzheimer's Disease Psychosis
Where
Alexandria, Anaheim, Augusta, Austin, Bellevue, Boca Raton, Dayton, Deerfield Beach, Denver, Doral, Homestead, Independence, Las Vegas, Long Beach, McKinney, Miami, Miami Gardens, Murrieta, Naples, New York, Orange, Orlando, Phoenix, Port Royal, San Diego, Scottsdale, Snellville, Sugarland, Tampa, Tigard, Tucson, West Long Branch, West Palm Beach
Age
55 years to 90 years
People
300 worldwide
Run by
MapLight Therapeutics
See details and how to joinNCT06887192 · EU 2024-519820-26-00
No phaseTaking people
Evaluation of Treatment Satisfaction and KarXT Utilization Registry (RESKU)
Where
Baltimore, Bel Air, Belle Mead, Belmont, Boston, Catonsville, El Paso, Evanston, Fort Mill, Grand Island, Kinston, Longview, Miami, New York, Omaha, Orange, Rose Hill, San Jose, South Dartmouth, Westlake
Age
18 years and over
People
300
Run by
Bristol-Myers Squibb
See details and how to joinNCT07101094
Phase 2Not yet taking people in United States
Brain Imaging of DSP-2342
Where
Baltimore
Age
18 years to 50 years
People
20
Run by
Johns Hopkins University
See details and how to joinNCT07850102
No phaseEnrolling by invitation
Effectiveness of mHealth Post-discharge Intervention for Patients With Severe Mental Illness
Where
Providence
Age
18 years and over
People
180
Run by
Butler Hospital
See details and how to joinNCT05703412
Phase 3Taking people
NBI-1117568-SCZ3030: Evaluation of NBI-1117568 in Inpatient Adults With Schizophrenia
Where
Atlanta, Culver City, Garden Grove, Hollywood, Little Rock, North Canton, Riverside
Age
18 years to 65 years
People
284 worldwide
Run by
Neurocrine Biosciences
See details and how to joinNCT07105098 · EU 2025-521215-39-00
Phase 3Taking people
NBI-1117568-SCZ3032: Long-Term Evaluation of NBI-1117568 in Adults With Schizophrenia
Where
Atlanta, Atlantis, Austin, Aventura, Bellevue, Boston, Bryant, Cedarhurst, Cerritos, Chicago, Chino, Culver City, Decatur, DeSoto, Doral, Flowood, Gaithersburg, Garden Grove, Hollywood, Houston, La Habra, Lemon Grove, Little Rock, Maitland, Marlton, Miami, Miami Lakes, New York, North Canton, Oak Brook, Oceanside, Orem, Peachtree Corners, Philadelphia, Pico Rivera, Riverside, San Diego, Sherman, Staten Island, St Louis, Tampa, The Bronx, Torrance, Watertown, West Hills, West Palm Beach
Age
18 years to 65 years
People
600 worldwide
Run by
Neurocrine Biosciences
See details and how to joinNCT07114874 · EU 2025-521216-19-00
Phase 3Taking people
Efficacy of NBI-1117568 in Preventing Relapse in Adults With Schizophrenia
Where
Atlanta, Bellevue, Boston, Cedarhurst, DeSoto, Flowood, Garden Grove, Hollywood, La Habra, Lemon Grove, Maitland, Marlton, Miami, New York, Oceanside, Tampa, The Bronx, Torrance, West Hills, West Palm Beach
Age
18 years to 65 years
People
560 worldwide
Run by
Neurocrine Biosciences
See details and how to joinNCT07227818