Schizophrenia trials in United States

In United States 179 Also abroad 473

179 trials · From ClinicalTrials.gov, checked 11 November 2026. Ask the study team whether a trial fits you.

No phaseNot yet taking people in United States
Frontal Gamma Coherence Neurofeedback for Patients With Schizophrenia
Where
La Jolla
Age
18 years to 55 years
People
30
Run by
BioSignal Solutions LLC
See details and how to joinNCT07659938
No phaseTaking people
State Representation in Early Psychosis 2
Where
Minneapolis
Age
15 years to 45 years
People
500
Run by
University of Minnesota
See details and how to joinNCT07834203
Phase 4Taking people
A Study to Evaluate the Effectiveness of Valbenazine in Adult Participants With Tardive Dyskinesia (TD) Who Remain Symptomatic While Receiving or After Stopping a Vesicular Monoamine Transporter 2 (VMAT2) Inhibitor
Where
Augusta, Austin, Bonita Springs, Bryant, Chino, Fresno, Hialeah, Independence, Long Beach, Miami, Naperville, Omaha, Orange, Orange City, Port Charlotte, Redlands, Richmond, San Diego, Tampa
Age
18 years and over
People
100
Run by
Neurocrine Biosciences
See details and how to joinNCT07105111
Phase 1Taking people
A Study of LTX-001 In Adult Participants With Acute Exacerbation of Schizophrenia
Where
Decatur, DeLand, Gaithersburg, Hollywood, Little Rock, Los Alamitos, Marlton, Miami Lakes, Richardson
Age
18 years to 55 years
People
90
Run by
Leal Therapeutics, Inc
See details and how to joinNCT07734493
No phaseTaking people
Circuitry-Guided Smoking Cessation in Schizophrenia (UH3)
Where
Houston
Age
22 years to 65 years
People
50
Run by
The University of Texas Health Science Center, Houston
See details and how to joinNCT05276050
Phase 2Taking people
A Study to Assess Adverse Events, Change in Disease Activity, and How Oral Emraclidine Moves Through the Body in Adult Participants With Schizophrenia
Where
Austin, Gaithersburg, Glendale, Little Rock, Los Alamitos, Marlton, Richardson
Age
18 years to 65 years
People
268
Run by
AbbVie
See details and how to joinNCT07145918
Phase 3Taking people
Evenamide, a Glutamate Release Modulator, as Add-On to Standard of Care in Subjects With Documented Treatment-Resistant Schizophrenia
Where
Atlanta, Baltimore, Los Angeles, Miami, New York
Age
18 years and over
People
400 worldwide
Run by
Newron Pharmaceuticals SPA
See details and how to joinNCT07184619
Phase 3Taking people
52-week Open Label Safety-Tolerability Study
Where
Anaheim, Atlanta, Bentonville, Canton, Cerritos, Chandler, Chicago, Culver City, DeSoto, Gaithersburg, Hollywood, Las Vegas, Little Rock, Miami Lakes, New York, Philadelphia, Richardson, San Diego, Snellville, St Louis, West Palm Beach
Age
18 years to 65 years
People
900
Run by
LB Pharmaceuticals Inc.
See details and how to joinNCT07369154
Phase 1Taking people
Genetic Basis of the Risk and Consequences of Cannabis Exposure in Humans
Where
West Haven
Age
21 years to 60 years
People
215
Run by
Yale University
See details and how to joinNCT06058702
Phase 1Taking people
A Study to Evaluate the Safety, Tolerability, and PK of an Injectable Form of KarXT
Where
Atlanta, Austin, Chicago, Decatur, Hollywood, Los Alamitos, Marlton, Miami Lakes
Age
18 years to 55 years
People
131
Run by
Bristol-Myers Squibb
See details and how to joinNCT07061288
No phaseTaking people
Activities to Change Your Mood: A Test of the Acceptability and Initial Efficacy in Clinical Samples and Healthy Controls
Where
Birmingham
Age
18 years to 65 years
People
200
Run by
University of Alabama at Birmingham
See details and how to joinNCT06911723
No phaseTaking people
Cerebellar Modulation of Cognition in Psychosis
Where
Belmont, Boston
Age
18 years to 55 years
People
95
Run by
Mclean Hospital
See details and how to joinNCT06107764
No phaseTaking people
Enhancing Veteran-Clinical Collaboration in VA PRRCs
Where
Albuquerque, San Diego, West Los Angeles
Age
18 years and over
People
119
Run by
VA Office of Research and Development
See details and how to joinNCT06898879
No phaseNot yet taking people in United States
Enhancing Brain Connectivity in Schizophrenia Through Neuromodulation (Study 3)
Where
Houston
Age
18 years to 60 years
People
120
Run by
The University of Texas Health Science Center, Houston
See details and how to joinNCT07772349
No phaseTaking people
Ketogenic and Nutritional Interventions for First Episode Bipolar Disorder
Where
Belmont
Age
18 years to 45 years
People
50
Run by
Mclean Hospital
See details and how to joinNCT06221852
No phaseEnrolling by invitation
Open Label Extension Study of NCT06221852
Where
Belmont
Age
18 years to 45 years
People
50
Run by
Mclean Hospital
See details and how to joinNCT06558201
Phase 3Enrolling by invitation
Long-term Safety Extension Study of OLZ/SAM in Pediatric Subjects
Where
Chicago, Cincinnati, Decatur, Dothan, Everett, Indianapolis, Lincoln, Little Rock, Miami Lakes, New York, Richmond, Saint Charles, Stanford, Washington D.C., West Chester
Age
10 years to 17 years
People
236 worldwide
Run by
Alkermes, Inc.
See details and how to joinNCT04987229
Phase 3Taking people
Study to Evaluate Weight Gain as Assessed by Change in BMI Z-score in Pediatric Subjects With Schizophrenia or Bipolar I Disorder
Where
Chicago, Cincinnati, Colorado Springs, Decatur, Denver, DeSoto, Dothan, Encino, Everett, Fort Worth, Hartford, Indianapolis, Kinston, Lincoln, Little Rock, Miami, Miami Lakes, New York, Omaha, Paramus, Richmond, Saint Charles, Stanford, Upland, Washington D.C., West Chester
Age
10 years to 17 years
People
220 worldwide
Run by
Alkermes, Inc.
See details and how to joinNCT05303064
Phase 1Taking people
Determining Efficacy and Safety of BXCL501 in Agitation Associated With Pediatric Schizophrenia and Bipolar Disorder
Where
Anaheim, Atlanta, Decatur, DeSoto, Hialeah
Age
10 years to 17 years
People
140
Run by
BioXcel Therapeutics Inc
See details and how to joinNCT05025605
No phaseTaking people
Enhancing Prefrontal Oscillations and Working Memory in Early-course Schizophrenia
Where
Pittsburgh
Age
18 years to 40 years
People
75
Run by
Fabio Ferrarelli
See details and how to joinNCT05102929
No phaseTaking people
Inter-Brain Synchrony in Schizophrenia
Where
Los Angeles
Age
18 years to 65 years
People
100
Run by
University of California, Los Angeles
See details and how to joinNCT07177261
Phase 2Enrolling by invitation
An Open-Label Study of ML-007C-MA in Adults With Alzheimer's Disease Psychosis
Where
Anaheim, Doral, Miami, Miami Gardens, Orlando
Age
55 years to 91 years
People
210 worldwide
Run by
MapLight Therapeutics
See details and how to joinNCT07459660 · EU 2025-521757-16-00
No phaseTaking people
Bilateral Prefrontal and Insular TMS for Depression in Schizophrenia
Where
Houston
Age
18 years to 60 years
People
120
Run by
The University of Texas Health Science Center, Houston
See details and how to joinNCT07060066
No phaseNot yet taking people in United States
LIFU Effects & Outcomes: Mechanisms Evaluating Striatal Systems Imaging (LEO MESSI)
Where
San Francisco
Age
18 years to 64 years
People
12
Run by
University of California, San Francisco
See details and how to joinNCT07710989
No phaseTaking people
Improving Cognition Through Telehealth Aerobic Exercise and Cognitive Training After a First Schizophrenia Episode
Where
Los Angeles
Age
18 years to 45 years
People
100
Run by
University of California, Los Angeles
See details and how to joinNCT05890183