Schizophrenia: open trials in United States

176 open trials have a site in United States. Registry data; only the trial team decides who can take part.

NCT07734493
A Study of LTX-001 In Adult Participants With Acute Exacerbation of Schizophrenia
Trial Treatment · Phase 1 · Leal Therapeutics, Inc
CenExel iResearch, LLC, Decatur · University Clinical Research-DeLand, LLC d/b/a Accel Research Sites - DeLand Clinical Research Unit, DeLand · CBH Health LLC., dba CenExel Gaithersburg MD, Gaithersburg · CenExel Hollywood FL, Hollywood · Behavioral Clinical Research, Inc., Hollywood · Pillar Clinical Research, LLC, Little Rock · Collaborative Neuroscience Research, LLC, Los Alamitos · Hassman Research Institute, LLC, Marlton · Innovative Clinical Research, Inc., Miami Lakes · Pillar Clinical Research, LLC, Richardson
Registry updated 2026-09-17
NCT05276050
Circuitry-Guided Smoking Cessation in Schizophrenia (UH3)
Trial Treatment · The University of Texas Health Science Center, Houston
The University of Texas Health Science Center Houston, Houston
Registry updated 2026-09-16
NCT07145918
A Study to Assess Adverse Events, Change in Disease Activity, and How Oral Emraclidine Moves Through the Body in Adult Participants With Schizophrenia
Trial Treatment · Phase 2 · AbbVie
Community Clinical Research - Cross Park Drive /ID# 272977, Austin · Cbh Health - Gaithersburg /ID# 272932, Gaithersburg · California Clinical Trials Medical Group - Parexel /ID# 275751, Glendale · Woodland International Research Group /ID# 275747, Little Rock · CenExel Collaborative Neuroscience Research /ID# 273005, Los Alamitos · Cenexel Hassman Research Institute (Hri) /ID# 276128, Marlton · Pillar Clinical Research - Richardson /ID# 275715, Richardson
Registry updated 2026-09-15
NCT07184619
Evenamide, a Glutamate Release Modulator, as Add-On to Standard of Care in Subjects With Documented Treatment-Resistant Schizophrenia
Trial Treatment · Phase 3 · Newron Pharmaceuticals SPA
Grady Behavioral Health Center, -Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta · Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore · UCLA DGSOM, UCLA Health, UCLA Semel Institute, Los Angeles · University of Miami, Miller School of Medicine; Jackson Behavioral Health Hospital, Miami · Manhattan Psychiatric Center, The Nathan Kline Institute for Psychiatric Research, New York
Registry updated 2026-09-10
NCT07369154
52-week Open Label Safety-Tolerability Study
Trial Treatment · Phase 3 · LB Pharmaceuticals Inc.
Advanced Research Center, Anaheim · CenExel, Atlanta · Pillar Clinical Research, Bentonville · Neuro-Behavioral Clinical Research, Canton · Synapse Clinical Trials, Cerritos · Chandler Clinical Trials, Chandler · Pillar Clinical Research, Chicago · CenExel, Culver City · ProScience Research Group, Culver City · Adams Clinical, DeSoto · CenExel Gaithersburg, Gaithersburg · CenExel, Hollywood · Redbird Research, Las Vegas · Woodland International Research Group, Little Rock · Pillar Clinical Research, Little Rock · Segal Trials, Miami Lakes · Neuro-Behavioral Clinical Research, New York · Adams Clinical, Philadelphia · Pillar Clinical Research, Richardson · Synergy San Diego, San Diego · Accelerated Clinical Trial, Snellville · Arch Clinical Trials, St Louis · Health Synergy Clinical Research, West Palm Beach
Registry updated 2026-09-09
NCT06058702
Genetic Basis of the Risk and Consequences of Cannabis Exposure in Humans
Trial Treatment · Phase 1 · Yale University
West Haven Veterans Affairs Medical Center, West Haven
Registry updated 2026-09-02
NCT07061288
A Study to Evaluate the Safety, Tolerability, and PK of an Injectable Form of KarXT
Trial Treatment · Phase 1 · Bristol-Myers Squibb
Atlanta Center for Medical Research, Atlanta · Community Clinical Research, Austin · Uptown Research Institute, Chicago · CenExel iResearch, LLC, Decatur · Research Centers of America (Hollywood), Hollywood · Collaborative Neuroscience Research, LLC, Los Alamitos · Hassman Research Institute Marlton Site, Marlton · Innovative Clinical Research, Inc., Miami Lakes
Registry updated 2026-09-02
NCT06911723
Activities to Change Your Mood: A Test of the Acceptability and Initial Efficacy in Clinical Samples and Healthy Controls
Trial Treatment · University of Alabama at Birmingham
University of Alabama at Birmingham, Birmingham
Registry updated 2026-08-31
NCT06107764
Cerebellar Modulation of Cognition in Psychosis
Trial Treatment · Mclean Hospital
McLean Hospital, Belmont · Beth Israel Deaconess Medical Center, Boston
Registry updated 2026-08-20
NCT06898879
Enhancing Veteran-Clinical Collaboration in VA PRRCs
Trial Treatment · VA Office of Research and Development
New Mexico VA Health Care System, Albuquerque, NM, Albuquerque · VA San Diego Healthcare System, San Diego, CA, San Diego · VA Greater Los Angeles Healthcare System, West Los Angeles, CA, West Los Angeles
Registry updated 2026-08-19
NCT07772349
Enhancing Brain Connectivity in Schizophrenia Through Neuromodulation (Study 3)
Trial Treatment · The University of Texas Health Science Center, Houston
The University of Texas Health Science Center Houston, Houston
Registry updated 2026-08-19
NCT06221852
Ketogenic and Nutritional Interventions for First Episode Bipolar Disorder
Trial Treatment · Mclean Hospital
McLean Hospital, Belmont
Registry updated 2026-08-17
NCT06558201
Open Label Extension Study of NCT06221852
Trial Treatment · Mclean Hospital
McLean Hospital, Belmont
Registry updated 2026-08-17
NCT04987229
Long-term Safety Extension Study of OLZ/SAM in Pediatric Subjects
Trial Treatment · Phase 3 · Alkermes, Inc.
Chicago · Cincinnati · Decatur · Dothan · Everett · Indianapolis · Lincoln · Little Rock · Miami Lakes · New York · Richmond · Saint Charles · Stanford · Washington D.C. · West Chester
Registry updated 2026-08-14
NCT05303064
Study to Evaluate Weight Gain as Assessed by Change in BMI Z-score in Pediatric Subjects With Schizophrenia or Bipolar I Disorder
Trial Treatment · Phase 3 · Alkermes, Inc.
Chicago · Cincinnati · Colorado Springs · Decatur · Denver · DeSoto · Dothan · Encino · Everett · Fort Worth · Hartford · Indianapolis · Kinston · Lincoln · Little Rock · Miami · Miami Lakes · New York · Omaha · Paramus · Richmond · Saint Charles · Stanford · Upland · Washington D.C. · West Chester
Registry updated 2026-08-14
NCT05025605
Determining Efficacy and Safety of BXCL501 in Agitation Associated With Pediatric Schizophrenia and Bipolar Disorder
Trial Treatment · Phase 1 · BioXcel Therapeutics Inc
Anaheim · Atlanta · Decatur · DeSoto · Hialeah
Registry updated 2026-08-11
NCT05102929
Enhancing Prefrontal Oscillations and Working Memory in Early-course Schizophrenia
Trial Treatment · Fabio Ferrarelli
University of Pittsburgh, Pittsburgh
Registry updated 2026-08-11
NCT07177261
Inter-Brain Synchrony in Schizophrenia
Trial Treatment · University of California, Los Angeles
University of California, Los Angeles, Los Angeles
Registry updated 2026-08-11
NCT07459660
An Open-Label Study of ML-007C-MA in Adults With Alzheimer's Disease Psychosis
Trial Treatment · Phase 2 · MapLight Therapeutics
Anaheim · Doral · Miami · Miami Gardens · Orlando
Registry updated 2026-08-07
NCT07060066
Bilateral Prefrontal and Insular TMS for Depression in Schizophrenia
Trial Treatment · The University of Texas Health Science Center, Houston
The University of Texas Health Science Center at Houston, Houston
Registry updated 2026-08-05
NCT07710989
LIFU Effects & Outcomes: Mechanisms Evaluating Striatal Systems Imaging (LEO MESSI)
Trial Treatment · University of California, San Francisco
University of California San Francisco, San Francisco
Registry updated 2026-08-05
NCT05890183
Improving Cognition Through Telehealth Aerobic Exercise and Cognitive Training After a First Schizophrenia Episode
Trial Treatment · University of California, Los Angeles
UCLA Aftercare Research Program, Los Angeles
Registry updated 2026-08-04
NCT02916810
Alternative Stimulation Mode and Location for Auditory Hallucination Neuromodulation Treatment
Trial Treatment · The University of Texas Health Science Center, Houston
The University of Texas Health Science Center at Houston, Houston
Registry updated 2026-08-03
NCT06969755
Biomarkers to Enhance Early Schizophrenia Treatment
Trial Treatment · Phase 4 · Northwell Health
McLean, Belmont · The University of Alabama at Birmingham, Birmingham · Feinstein Institute for Medical Research, Glen Oaks · University of California San Diego, La Jolla
Registry updated 2026-07-31
NCT07417904
BRAVE Program to Improve Safety and Reduce Violence Risk in Early Psychosis
Trial Treatment · Howard University
Howard University Hospital, Washington D.C.
Registry updated 2026-07-29

All Schizophrenia trials and the map

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