Schizophrenia: open trials in United States

177 open trials have a site in United States. Registry data; only the trial team decides who can take part.

NCT07417904
BRAVE Program to Improve Safety and Reduce Violence Risk in Early Psychosis
Trial Treatment · Howard University
Howard University Hospital, Washington D.C.
Registry updated 2026-07-29
NCT07467993
Study to Assess the Safety, Tolerability, and Treatment Response of GXV813 in Hospitalized Adults With Schizophrenia
Trial Treatment · Phase 2 · Novartis Pharmaceuticals
Pillar Clinical Research LLC, Bentonville · Uptown Research Institute, LLC, Chicago · Pillar Clinical Research LLC, Chicago · CenExel iResearch, Decatur · Segal Institute for Clinical Research, Miami · CNRI-Los Angeles, LLC, Pico Rivera · Arch Clinical Trials, LLC, St Louis
Registry updated 2026-07-29
NCT07565428
Study to Evaluate Efficacy and Safety of Roluperidone in Adult Subjects With Negative Symptoms and Stable Positive Symptoms of Schizophrenia and to Evaluate the Relapse Rate of Roluperidone and Antipsychotic Medications
Trial Treatment · Phase 3 · Minerva Neurosciences
Atlanta Center for Medical Research, LLC, Atlanta · Clinical Innovations, Inc. dba CITrials, Bellflower · ProScience Research Group, Culver City · CenExel iResearch, LLC, Decatur · CBH Health, LLC dba CenExel, Gaithersburg · Collaborative NeuroScience Research , LLC, Garden Grove · Velocity Clinical Research, Hallandale Beach, Hallandale · Behavioral Clinical Research, Inc., Hollywood · Hassman Research Institute, LLC dba CenExel, Marlton · New York State Psychiatric Institute, New York · Pillar Clinical Research, LLC, Richardson · Clinical Innovations, Inc. dba CITrials, Riverside · ForCare Clinical Research, Tampa
Registry updated 2026-07-28
NCT05617898
Determining the Role of Social Reward Learning in Social Anhedonia
Trial Treatment · University of Alabama at Birmingham
University of Alabama at Birmingham, Birmingham · University of California, Los Angeles, Los Angeles
Registry updated 2026-07-27
NCT07363577
Study to Evaluate LB-102 for the Treatment of Adult Patients With Acute Schizophrenia
Trial Treatment · Phase 3 · LB Pharmaceuticals Inc.
Pillar Clinical Research, Bentonville · Health Synergy Clinical Research, Boynton Beach · Pillar Clinical Research, Chicago · ProScience Research Group, Culver City · CenExel, Garden Grove · Synergy San Diego, Lemon Grove · Woodland International Research Group, Little Rock · Pillar Clinical Research, Little Rock · Innovative Clinical Research, Miami Lakes · Neuro-Behavioral Clinical Research, North Canton · Clinical Innovations, Inc., Riverside · Accelerated Clinical Trial, Snellville · Arch Clinical Trials, St Louis
Registry updated 2026-07-27
NCT07263022
Cognitive Strategies in Early Psychosis 2
Trial Treatment · Phase 3 · University of Minnesota
University of Minnesota, Minneapolis
Registry updated 2026-07-23
NCT07713849
Transition Care for FEP
Research · University of Chicago
University of Chicago Medical Center, Biological Science Division, Chicago · University of Chicago Ingalls Memorial Hospital, Harvey
Registry updated 2026-07-20
NCT05770375
Tolerability of MDMA in Schizophrenia
Trial Treatment · Phase 1/2 · Anya Bershad, MD, PhD
UCLA, Los Angeles
Registry updated 2026-07-17
NCT04940663
Neurobehavioral Mechanisms of Social Isolation and Loneliness in Serious Mental Illness
Trial Treatment · Massachusetts General Hospital
Massachusetts General Hospital, Charlestown
Registry updated 2026-07-16
NCT06376734
Search for Novel Transcranial Magnetic Stimulation (TMS) Targets for Mental Illness
Trial Treatment · Phase 2 · Brigham and Women's Hospital
Brigham and Women's Hospital, Boston · Acacia Clinics, Sunnyvale
Registry updated 2026-07-16
NCT07423546
A PET/MRI Study of Cobenfy on Dopamine Transmission in Schizophrenia
Trial Treatment · Phase 1/2 · New York State Psychiatric Institute
New York State Psychiatric Institute, New York
Registry updated 2026-07-14
NCT07703670
MicroRNAs as Biomarkers in First Episode Schizophrenia
Trial Treatment · Northwell Health
Zucker Hillside Hospital, Glen Oaks
Registry updated 2026-07-14
NCT06562608
Anticholinergic Deprescription in Schizophrenia
Trial Treatment · Phase 4 · Deepak K. Sarpal, M.D.
UPMC Western Psychiatric Hospital/University of Pittsburgh, Pittsburgh
Registry updated 2026-07-10
NCT03906435
Preventing Vulnerable Child Syndrome in the NICU With Cognitive Behavioral Therapy (PreVNT Trial)
Trial Treatment · University of Texas Southwestern Medical Center
Parkland Health & Hospital System, Dallas
Registry updated 2026-07-09
NCT04887792
Acetazolamide for Treatment Resistant Schizophrenia
Trial Treatment · Phase 1/2 · Vishwajit Nimgaonkar, MD PhD
University of Pittsburgh, Pittsburgh
Registry updated 2026-07-07
NCT06345963
Enhancing Brain Connectivity in Schizophrenia Through Neuromodulation (Study 1)
Trial Treatment · The University of Texas Health Science Center, Houston
The University of Texas Health Science Center Houston, Houston
Registry updated 2026-07-07
NCT06961916
Enhancing Brain Connectivity in Schizophrenia Through Neuromodulation (Study 2)
Trial Treatment · The University of Texas Health Science Center, Houston
The University of Texas Health Science Center Houston, Houston
Registry updated 2026-07-07
NCT07119268
SPARK Healthy Sleep
Trial Treatment · Indiana University
Indiana University, Indianapolis
Registry updated 2026-07-07
NCT05157620
Exercise-based Program for Rehabilitation of Veterans With Severe Mental Illness
Trial Treatment · VA Office of Research and Development
VA Pittsburgh Healthcare System University Drive Division, Pittsburgh, PA, Pittsburgh
Registry updated 2026-07-01
NCT06947941
A Study to Evaluate Safety and Efficacy of KarXT + KarX-EC as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-5)
Trial Treatment · Phase 3 · Bristol-Myers Squibb
Inland Psychiatric Medical Group., Chino · Cleveland · Gilbert Neurology Partners/CCT Research, Gilbert · Insight Clinical Trials LLC - Independence, Independence · Naples · Naples
Registry updated 2026-06-30
NCT07674914
A Cognitive Mobile Intervention for Motivation in Psychotic Disorders
Trial Treatment · Phase 1/2 · University of Alabama at Birmingham
University of Alabama at Birmingham, Birmingham
Registry updated 2026-06-30
NCT07658391
Optimizing CBSST With Executive Function Training for Schizophrenia (R33)
Trial Treatment · University of California, San Diego
UT Southwestern Medical Center, Dallas · University of California San Diego, San Diego
Registry updated 2026-06-23
NCT06774417
Digital Strategies to Advance Help-Seeking - Aim 3
Trial Treatment · Columbia University
Columbia University Irving Medical Center, New York
Registry updated 2026-06-18
NCT07434479
A Virtual Reality Mindfulness Application for Aggression in Schizophrenia
Trial Treatment · Manhattan Psychiatric Center
Manhattan Psychiatric Center, New York · NewYork-Presbyterian/Weill Cornell Medical Center Westchester Division, White Plains
Registry updated 2026-06-10
NCT06257056
Deep Brain Stimulation for Psychosis
Trial Treatment · Bradley Lega
UT Southwestern Medical Center, Dallas
Registry updated 2026-06-09

All Schizophrenia trials and the map

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