Type 2 diabetes: open trials in United Kingdom

60 open trials have a site in United Kingdom. Registry data; only the trial team decides who can take part.

NCT07668336
A Study of Orforglipron (LY3502970) Compared With Dulaglutide in Pediatric Participants With Type 2 Diabetes
Trial Treatment · Phase 3 · Eli Lilly and Company
Hull Royal Infirmary, Hull · Alder Hey Children's Hospital, Liverpool · Royal London Hospital, London
Registry updated 2026-11-05
NCT06897475
A Study of LY3457263 Compared With Placebo in Participants With Type 2 Diabetes on a Stable Dose of Semaglutide or Tirzepatide
Trial Treatment · Phase 2 · Eli Lilly and Company
FutureMeds - Birmingham, Birmingham · Layton Medical Centre, Blackpool · Southmead Hospital, Bristol · FutureMeds - Liverpool, Bromborough · Futuremeds-Newcastle, Newcastle · Newquay Health Centre, Newquay · George Eliot Hospital, Nuneaton · The Adam Practice, Poole · Clifton Medical Centre, Rotherham · Rame Group Practice, Torpoint
Registry updated 2026-11-04
NCT07881432
A Study of EloraTZP in Adult Participants With Obesity Without Type 2 Diabetes
Trial Treatment · Phase 3 · Eli Lilly and Company
Layton Medical Centre, Blackpool · Ashton Medical Group - Chapel House, Lancashire · St Pancras Clinical Research, London · Atlantic Medical, Penzance · Abbeywell Surgery, Romsey · Marine Lake Medical Practice, West Kirby
Registry updated 2026-11-03
NCT07662109
A Phase III Study to Investigate the Efficacy and Safety of the Combination of Elecoglipron and Dapagliflozin in Adults With Type 2 Diabetes Mellitus
Trial Treatment · Phase 3 · AstraZeneca
Blackburn · Dundee · Guisborough · Nantwich · Rotherham · Thetford · Weston-super-Mare · Witney · Woodbridge · Yate
Registry updated 2026-10-30
NCT07064473
EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease
Trial Treatment · Phase 3 · Boehringer Ingelheim
FutureMeds - Birmingham, Birmingham · Royal Blackburn Teaching Hospital, Blackburn · Royal Bournemouth Hospital, Bournemouth · Bradford Royal Infirmary, Bradford · Yatton Surgery, Bristol · Coniston Medical Practice, Bristol · FutureMeds - Liverpool, Bromborough · St Richard's Hospital, Chichester · Queen Alexandra Hospital, Cosham · Darlington Memorial Hospital, Darlington · Royal Derby Hospital, Derby · Ninewells Hospital & Medical School, Dundee · The Falmouth Health Centre Practice, Falmouth · The Garth Surgery, Guisborough · Ipswich Hospital (UK), Ipswich · Victoria Hospital, Kirkcaldy · Royal Lancaster Infirmary, Lancaster · Pinfold Surgery, Leeds · Lincoln County Hospital, Lincoln · FutureMeds - London, London · William Harvey Research Limited, London · North Manchester General Hospital, Manchester · Wythenshawe Hospital, Manchester · Manchester Royal Infirmary, Manchester · Linthorpe Surgery, Middlesbrough · FutureMeds - Newcastle, Newcastle upon Tyne · Mayford House Surgery, Northallerton · Norfolk and Norwich University Hospital, Norwich · Moorgreen Hospital, Southampton · Swansea University Medical School, Swansea · Trowbridge Health Centre, Trowbridge · Weymouth Research Hub, Weymouth · Woodthorpe Surgery, York
Registry updated 2026-10-28
NCT07784270
A Study to Evaluate Effect of AZD6234 in Adult Participants With Type 2 Diabetes Mellitus and Obesity or Overweight
Trial Treatment · Phase 3 · AstraZeneca
Chippenham · Corby · Dunfermline · Hull · Northwood
Registry updated 2026-10-28
NCT07285811
GLycaemic Outcomes With Whey Protein in ageING
Trial Treatment · University of Birmingham
Heartlands Hospital, Birmingham · School of Sport, Exercise and Rehabilitation Sciences, University of Birmingham, Birmingham
Registry updated 2026-10-22
NCT07662213
A Study to Find Out if the Study Drug Elecoglipron Helps Adults With Type 2 Diabetes Mellitus by Comparing it With Semaglutide, a Medicine Already Used to Treat Type 2 Diabetes Mellitus
Trial Treatment · Phase 3 · AstraZeneca
Aberdeen · Addlestone · Banbury · Bristol · Edinburgh · Hounslow · Penzance · Poole · Soham · Wansford · Yate
Registry updated 2026-10-22
NCT07422532
A Multi-centre Trial to Assess the Efficacy and Safety of the Omnipod 5 System in People With Type 2 Diabetes Undergoing Haemodialysis
Trial Treatment · Imperial College London
Royal Derby Hospital, Derby · Hammersmith Hospital, London · Guys and St Thomas' Hospitals, London · Manchester Royal Infirmary, Manchester
Registry updated 2026-10-19
NCT06451757
KHENERFIN Study: A Trial to Evaluate the Efficacy and Safety of Sonlicromanol in Primary Mitochondrial Diseases
Trial Treatment · Phase 3 · Khondrion BV
University College London Hospitals NHS Foundation Trust National Hospital for Neurology and Neurosurgery, London
Registry updated 2026-10-14
NCT07351045
A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight Without Type 2 Diabetes
Trial Treatment · Phase 3 · Hoffmann-La Roche
Monklands Hospital, Airdrie · Birmingham Heartlands Hospital, Birmingham · Rowden Surgery, Chippenham · Queen Elizabeth University Hospital Glasgow, Glasgow · Leicester General Hospital, Leicester · Hammersmith Hospital, London · Royal Victoria Infirmary, Newcastle upon Tyne · Soham Staploe Medical Centre, Soham · Singleton Hospital, Swansea
Registry updated 2026-10-13
NCT07351058
A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight and Type 2 Diabetes
Trial Treatment · Phase 3 · Hoffmann-La Roche
Aberdeen Royal Infirmary, Aberdeen · Antrim Area Hospital, Antrim · Fylde Coast Clinical Research at Layton Medical Centre, Blackpool · Southmead General Hospital, Bristol · Ninewells Hospital and Medical School - Tayside Health Board, Dundee · HMC Health Group, Hounslow · Hull Royal Infirmary, Hull · George Eliot Hospital, Nuneaton · Knowle House Surgery, Plymouth · Musgrove Park Hospital, Taunton
Registry updated 2026-10-13
NCT07667803
A Master Protocol to Investigate Efficacy and Safety of Elecoglipron in Participants With Obesity or Overweight With or Without T2DM
Trial Treatment · Phase 3 · AstraZeneca
Ashton-under-Lyne · Blackpool · Chesterfield · Corby · Ely · Glasgow · Hounslow · Leicester · Metropolitan Borough of Wirral · Nantwich · Poole · Rotherham · Stowmarket · Wansford · Witney · Yate
Registry updated 2026-10-13
NCT07684144
Extension Trial to Evaluate the Long-term Efficacy, Safety, and Tolerability of Maridebart Cafraglutide (MARITIME-2-EXTENSION)
Trial Treatment · Phase 3 · Amgen
FutureMeds - Birmingham, Birmingham
Registry updated 2026-10-05
NCT06803771
Surveillance of Pancreatic Health After Diabetes Diagnosis
Trial Treatment · University Hospital Southampton NHS Foundation Trust
Ashton Medical Group, Ashton-under-Lyne · Yardley Wood Health Centre, Birmingham · Bournemouth Research Hub, Bournemouth · Brockwood Medical Practice, Brockham · Eastham Group Practice, Bromborough · Peel Croft Surgery, Burton-on-Trent · Integrated Care Partnership/ The Old Cottage Hospital, Epsom · South Leicestershire Medical Group, Kibworth Beauchamp · Kingswinford Medical Practice, Kingswinford · Park Medical Centre, Leek · Forest Medical Group, Leicester · The Cuckoo Lane Practice, London · South Westminster Centre, London · Willesden Medical Centre, London · Maidstone and Tunbridge Wells NHS Trust, Maidstone · Bowland Medical Practice, Manchester · Bodey Medical Centre, Manchester · The Maples Medical Centre, Manchester · King's Mill Hospital (Sherwood Forest) Research Van, Nottingham · Portsmouth Research Hub, Portsmouth · Hazelvalley Family Practice, Rossendale · Pembroke Centre (Hillingdon), Ruislip · Ashfields Primary Care Centre, Sandbach · Moorgreen Hospital, Southampton · Southampton Research Hub (Shirley Research Hub), Southampton · Trinity Court Surgery, Stratford-upon-Avon · Balance Street Health Centre, Uttoxeter · Civic Centre, Uxbridge · Quinton Practice, Walsall · Warlingham Green Medical Practice, Warlingham · Weymouth Research Hub, Weymouth
Registry updated 2026-09-28
NCT07776509
A Study to Evaluate Effect of AZD6234 as an Adjunct to Incretin-based Therapies in Adult Participants With Obesity or Overweight With Weight-related Comorbidity With or Without Type 2 Diabetes Mellitus
Trial Treatment · Phase 3 · AstraZeneca
Airdrie · Chippenham · Hull · Llandough · Rotherham
Registry updated 2026-09-25
NCT05663515
A Pan-European Post-Authorisation Safety Study: Risk of Pancreatic Cancer Among Type 2 Diabetes Patients Who Initiated Exenatide as Compared With Those Who Initiated Other Non-Glucagon-Like Peptide 1 Receptor Agonists Based Glucose Lowering Drugs
Research · AstraZeneca
Edinburgh · London
Registry updated 2026-09-24
NCT07321886
A Study of Eloralintide (LY3841136) in Participants With Obesity, or Overweight Without Type 2 Diabetes
Trial Treatment · Phase 3 · Eli Lilly and Company
Layton Medical Centre, Blackpool · Bradford on Avon Health Centre, Bradford on Avon · Ashton Medical Group - Chapel House, Lancashire · Royal Lancaster Infirmary, Lancaster · Altnagelvin Area Hospital, Londonderry · Bodyline Clinic - Openshaw, Manchester · Wansford Research Limited, Peterborough · Abbeywell Surgery, Romsey · Rame Group Practice, Torpoint
Registry updated 2026-09-22
NCT07828626
Benefits of Retained Insulin for Good Health
Research · Royal Devon and Exeter NHS Foundation Trust
D1 Wolfson Centre Research and Development, Bath · Clinical Research Centre, Bristol · NIHR Exeter Clinical Research Facility, Exeter · Diabetes and Endocrine Centre, Truro
Registry updated 2026-09-18
NCT07743450
A Study of Once-daily Oral ASC30 to Evaluate the Efficacy and Safety in Adult Participants With Obesity or Overweight With Type 2 Diabetes
Trial Treatment · Phase 3 · Ascletis Pharma (China) Co., Limited
Cardiff · Edgbaston · Glasgow · London · Manchester · Stoke-on-Trent · Warrington
Registry updated 2026-09-16
NCT07247084
A Study of Tirzepatide (LY3298176) Compared With Standard of Care in Adult Participants With Obesity and Without Diabetes (SURMOUNT-REAL UK)
Trial Treatment · Phase 4 · Eli Lilly and Company
P91604 St John's Medical Centre, Altrincham · P89008 Ashton Medical Group, Ashton-under-Lyne · Y02319 SSP Bolton General Practice, Bolton · P83012 Tower Family Healthcare, Bury · P91014 Washway Road Medical Centre, Cheshire · P88007 Cheadle Hulme Medical Group (was Cheadle Hulme Health Centre) (Bridge House), Cheshire · Y02790 SSP Bolton Medical Centre, Great Lever · P89002 The Brooke Surgery, Hyde SK14 · P83025 St Gabriels Medical Centre, Manchester · P84017 Ladybarn Group Practice, Manchester · P84678 Didsbury Medical Centre, Manchester · P91006 Urmston Group Practice, Manchester · P87019 Silverdale Medical Practice, Manchester · P84630 The Arch Medical Practice, Manchester · P84034 Barlow Medical Centre, Manchester · P84012 Northenden Group Practice, Manchester · P84068 Chorlton Family Practice, Manchester · P92620 SSP Ince Surgery (Lower Ince), Manchester · P84035 Bodey Medical Centre, Manchester · P86004 Peterloo Medical Centre, Manchester · P85011 CH Medical Practice, Oldham · P85010 Woodlands Medical Practice, Oldham · P86022 Stonefield Street Surgery, Rochdale · P91021 Firsway Health Centre, Sale · P91013 Boundary House Medical Centre, Sale · P87027 Langworthy Medical Practice, Salford · P88632 Stockport Medical Group, Stockport · P87025 The Lakes Medical Practice, Swinton · P87016 The Sides Medical Centre, Swinton · Y02322 SSP Leigh Family Practice, Wigen
Registry updated 2026-09-09
NCT07662135
A Phase III Study to Investigate the Efficacy and Safety of Elecoglipron Compared With Placebo in Adults With Type 2 Diabetes Mellitus and Impaired Renal Function on Background Dapagliflozin
Trial Treatment · Phase 3 · AstraZeneca
Blackpool · Glasgow · Hull · Penzance · Sandbach · Thetford · Whitney
Registry updated 2026-09-02
NCT04786262
A Safety, Tolerability, and Efficacy Study of VX-880 and VX-017 in Participants With Type 1 Diabetes
Trial Treatment · Phase 3 · Vertex Pharmaceuticals Incorporated
Royal Infirmary of Edinburgh, Edinburgh · Churchill Hospital, Headington · Cardiovascular, Metabolic Medicine and Sciences, King's College London, London · The Newcastle Upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne
Registry updated 2026-09-01
NCT07677995
Free Fatty Acid Effects In Type 2 Diabetes
Trial Treatment · University of Ulster
School of Biomedical Sciences, Coleraine
Registry updated 2026-09-01
NCT07797335
AMBITION 7: A Research Study Investigating How Well Zenagamtide Lowers Blood Sugar and Body Weight Compared to Insulin Glargine in People With Type 2 Diabetes and Increased Risk of Diseases That Affect the Heart and Blood Vessels Treated With 1-3 Other Diabetes Medications
Trial Treatment · Phase 3 · Novo Nordisk A/S
Southmead Hospital, Bristol · University Hospital Coventry - WISDEM Centre, Coventry · Hull Royal Infirmary - Diabetes, Hull · Ipswich Hospital - Diabetes, Ipswich · Altnagelvin Area Hospital, Londonderry · North Coast Medical Ltd, Newquay · Clifton Medical Centre, Rotherham · Joint Clinical Research Facility - Swansea, Swansea · Egremont Medical Centre, Wallasey · Yeovil Hospital, Yeovil
Registry updated 2026-09-01

All Type 2 diabetes trials and the map

This page is not medical advice. Talk to your doctor before contacting a trial.

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