Type 2 diabetes trials in United States

In United States 389 Also abroad 1200

389 trials · From ClinicalTrials.gov, checked 11 November 2026. Ask the study team whether a trial fits you.

Phase 3Taking people
A Study to Learn About Berobenatide Given Once Weekly in Adults With Knee Osteoarthritis and Overweight or Obesity With or Without Type 2 Diabetes (VESPER-OA 2)
Where
Birmingham, Miami, Shelby, Tucson
Age
18 years and over
People
756
Run by
Pfizer
See details and how to joinNCT07915609 · EU 2026-527180-15-00
No phaseTaking people
CGM-Enhanced DPP to Prevent Type 2 Diabetes in Adults With Prediabetes
Where
Buffalo
Age
18 years and over
People
100
Run by
State University of New York at Buffalo
See details and how to joinNCT07140848
Phase 2Taking people
A Study of Clazakizumab (LY5724886) in Adults With Elevated hsCRP and at Increased Risk for Cardiovascular Event
Where
Altamonte Springs, Buffalo, Cincinnati, Cutler Bay, Cypress, Dearborn, Foxborough, Glendora, Houston, Huntsville, Indianapolis, Kingwood, Las Vegas, Lombard, Maitland, Manassas, McKinney, North Charleston, Ogden, Olive Branch, Orlando, Reston, The Bronx, Tucson, West Chester, Woodstock, Yardley
Age
18 years and over
People
120 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT07783802
Phase 3Not yet taking people in United States
A Study of EloraTZP in Adult Participants With Obesity Without Type 2 Diabetes
Where
Albuquerque, Arlington, Atlantis, Baltimore, Bellaire, Boston, Chapel Hill, Chicago, Covina, Dallas, Dalton, Dunwoody, Euless, Eunice, Greensboro, Honolulu, Houston, Indianapolis, Kingwood, Las Vegas, Long Island City, Los Angeles, Maitland, Memphis, Mesa, Metairie, Miami, New Haven, Newport News, New York, Norfolk, Philadelphia, Plymouth Meeting, Raleigh, Ridgeland, Rolling Hills Estates, San Antonio, San Diego, Santa Ana, Scottsdale, Shavano Park, Stockbridge, Tamarac, Tampa, Tucson, Tyler, Union City, West Valley City
Age
18 years and over
People
2,115 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT07881432 · EU 2026-526047-34-00
Phase 2Not yet taking people in United States
A Study to Investigate the Effect of LY4086940 Versus Placebo in Participants With Obesity or Overweight and Without Type 2 Diabetes
Where
Amherst, Ammon, Austin, Chandler, Chicago, Cincinnati, City of Saint Peters, Dallas, Danville, Greenbrae, Greenville, Huntington Park, Las Vegas, Miami, Miami Lakes, Monroe, Morehead City, Nashville, Needham, New Bedford, New Bern, New Port Richey, Orlando, Rochester, Rolling Hills Estates, San Antonio, Scottsdale, Southfield, Springfield, Stamford, The Villages, Topeka, Troy, Tucson, Walnut Creek, Wenatchee, Weslaco, West Des Moines
Age
18 years to 75 years
People
460 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT07890376
Phase 3Not yet taking people in United States
A Study of Eloralintide (LY3841136) in Participants With Obesity or Overweight, Type 2 Diabetes, and Increased Cardiovascular Risk
Where
Altamonte Springs, Amarillo, Apache Junction, Arlington, Arlington Heights, Augusta, Baltimore, Birmingham, Brandon, Cincinnati, Corvallis, Covina, Cutler Bay, Dallas, East Providence, El Paso, Escondido, Exton, Fleming Island, Fort Worth, Franklin, Gilbert, Greenfield, Honolulu, Houston, Humble, Huntsville, Jacksonville, Lancaster, Las Vegas, Leesburg, Long Beach, Longview, McAllen, McKinney, Media, Miami, Morehead City, Nashua, New Bedford, Norfolk, Northridge, Ogden, Oxnard, Pasadena, Pembroke Pines, Phoenix, Port Charlotte, Redmond, Richmond, Ridgeland, Rochester, Saint Joseph, San Antonio, San Diego, Santa Clarita, Southfield, Springfield, Surprise, Tinley Park, Waterbury, Westlake Village, Wilmington, Wylie
Age
45 years to 64 years
People
3,000 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT07900633 · EU 2026-525919-14-00
No phaseNot yet taking people in United States
Clinical Research Trial to Study Insulin Sensitivity Using Automated Glucose Clamp Technology
Where
Webster
Age
18 years to 65 years
People
50
Run by
Profil Institut für Stoffwechselforschung GmbH
See details and how to joinNCT07913698
No phaseTaking people
Whole Food for Families: A Pilot RCT of a Dietary Guidelines-Based Intervention to Prevent Type 2 Diabetes
Where
Nashville
Age
6 years to 59 years
People
30
Run by
Vanderbilt University
See details and how to joinNCT06482944
No phaseNot yet taking people in United States
SWitching to Appropriate Prescription in Cardiovascular-Kidney-Metabolic Syndrome
Where
Pleasanton
Age
18 years and over
People
1,200
Run by
Kaiser Permanente
See details and how to joinNCT07910968
No phaseNot yet taking people in United States
Peer Support and Remote Patient Monitoring for Black Adults With Type 2 Diabetes
Where
Birmingham
Age
19 years and over
People
200
Run by
University of Alabama at Birmingham
See details and how to joinNCT07181304
No phaseNot yet taking people in United States
Role of Endothelial Dysfunction on Exercise Pressor Reflex in Type 2 Diabetes
Where
Milwaukee
Age
18 years to 80 years
People
40
Run by
Medical College of Wisconsin
See details and how to joinNCT07228208
No phaseTaking people
Culturally Tailored Program for Food-Insecure Adults: SPICE-D
Where
Winston-Salem
Age
18 years and over
People
25
Run by
Wake Forest University Health Sciences
See details and how to joinNCT07361341
Phase 3Taking people
A Phase III Study to Investigate the Efficacy and Safety of the Combination of Elecoglipron and Dapagliflozin in Adults With Type 2 Diabetes Mellitus
Where
Albuquerque, Annapolis, Atlanta, Bakersfield, Beachwood, Boston, Brooklyn, Chicago, Dallas, Elkhorn, Evansville, Huntsville, Kingsport, Kingwood, Lake City, Lakeland, Layton, Little Rock, Los Angeles, Lutherville-Timonium, Maumee, McKinney, Mobile, Nashville, Newport News, Norman, Ontario, Oxon Hill, Paris, Philadelphia, Raleigh, Redmond, Ridgeland, Rosedale, San Antonio, Sheffield, Sioux City, Skokie, South Jordan, Toms River, Troy, Vienna, Webster, Zachary
Age
18 years and over
People
2,000 worldwide
Run by
AstraZeneca
See details and how to joinNCT07662109 · EU 2025-523941-81-00
Phase 3Taking people
A Study to Evaluate Effect of AZD6234 in Adult Participants With Obesity or Overweight With Weight-related Comorbidity Without Type 2 Diabetes Mellitus
Where
Ames, Arlington, Bridgeport, Butte, Champaign, Chicago, Clearwater, Columbus, Cortland, Dothan, El Dorado, Escondido, Fargo, Houston, Huntsville, Jacksonville, Jefferson City, Jersey City, Kansas City, Kingsport, Las Vegas, Maumee, Memphis, Mesa, Owensboro, Philadelphia, Portland, Renton, Rochester, Rocky Mount, Salt Lake City, San Antonio, Seattle, Smithfield, Statesville, Stockbridge, Sugar Land, Troy, Tulsa, Waco, Wilmington
Age
18 years and over
People
2,500 worldwide
Run by
AstraZeneca
See details and how to joinNCT07784725 · EU 2025-523379-41-00
No phaseNot yet taking people in United States
Physiologic Insulin Resensitization (PIR) Treatment in Patients With a Diagnosis of Type 2 Diabetes Mellitus (T2DM)
Where
Birmingham
Age
18 years and over
People
60
Run by
University of Alabama at Birmingham
See details and how to joinNCT07906470
No phaseEnrolling by invitation
Personalizing A1c Using Hematologic Indices and CGM for Accurate Diabetes Diagnosis
Where
Boston
Age
65 years and over
People
45
Run by
Brigham and Women's Hospital
See details and how to joinNCT07111416
No phaseTaking people
Neuromodulation for Metabolic Dysfunction
Where
Lexington
Age
18 years and over
People
120
Run by
Rahul Sachdeva
See details and how to joinNCT07597161
Phase 3Taking people
A Study to Test Whether Survodutide Helps People With Type 2 Diabetes Control Their Blood Sugar
Where
Albuquerque, Austin, Birmingham, Blackfoot, Bluffton, Brooklyn, Brownsville, Buckley, Canoga Park, Canton, Chattanooga, Clearwater, Columbus, Concord, Conroe, Dallas, Dearborn, Escondido, Fayetteville, Fort Myers, Georgetown, Gilbert, Greensboro, Hollywood, Honolulu, Houston, Idaho Falls, Kalispell, Lakeland, Largo, Las Vegas, Lawrenceville, Lexington, Lincoln, Little Rock, Long Beach, Maumee, Memphis, Meridian, Mesquite, Miami, Minneapolis, Missoula, Morehead City, Newport News, Northridge, Oklahoma City, Olive Branch, Paradise Valley, Phoenix, Pittsburgh, Redmond, Riverview, Rockville, Salt Lake City, San Antonio, Shavano Park, Spartanburg, Spring Valley, Troy, Union City, Uniontown, University Park, Walnut Creek, West Hills, Weston, Winter Park
Age
18 years and over
People
600 worldwide
Run by
Boehringer Ingelheim
See details and how to joinNCT07754461
No phaseNot yet taking people in United States
Care COMPASS Study
Where
Portland
Age
18 years and over
People
200
Run by
Fitbit LLC
See details and how to joinNCT07904793
No phaseTaking people
Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford
Where
Sioux Falls
People
20,000
Run by
Sanford Health
See details and how to joinNCT01793168
Phase 2Not yet taking people in United States
The Effects of Glucagon on Hepatic Metabolism in People With Type 2 Diabetes After Caloric Restriction
Where
Rochester
Age
25 years to 65 years
People
20
Run by
Adrian Vella
See details and how to joinNCT05499702
Phase 3Taking people
EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease
Where
Albany, Albuquerque, Anniston, Aurora, Austin, Avon, Baltimore, Beaver, Beverly Hills, Billings, Binghamton, Boca Raton, Bossier City, Bowling Green, Bridgeport, Bridgewater, Brownsville, Buffalo, Camp Hill, Canoga Park, Cary, Chandler, Chapel Hill, Chicago, Cincinnati, Clearwater, Columbus, Concord, Covington, Cutler Bay, Dakota Dunes, Dallas, Dearborn, DeLand, Doral, El Dorado, Elkhart, El Paso, Fairhope, Falls Church, Fargo, Fayette, Fleming Island, Flint, Forney, Fort Mill, Fort Myers, Fort Worth, Franklin, Fremont, Gaffney, Golden, Greenfield, Greenville, Guntersville, Hallandale, Hamden, Honolulu, Houston, Huntington Park, Idaho Falls, Jacksonville, Jefferson City, Johns Creek, Kansas City, Kenosha, Kissimmee, Knoxville, Lake City, Lakeland, La Mesa, Lancaster, Las Vegas, Lenoir, Lewisville, Lexington, Linden, Lombard, Long Beach, Macon, Malden, Manassas, Marietta, Mesquite, Methuen, Miami, Miami Lakes, Monroe, Mooresville, Morehead City, Morgantown, Muncie, Naples, New Port Richey, New York, Norfolk, North Las Vegas, Oak Lawn, Oklahoma City, Olney, Omaha, Orange, Orlando, Ormond Beach, Owensboro, Oxon Hill, Palm Beach Gardens, Palmetto Bay, Pembroke Pines, Philadelphia, Phoenix, Pittsburgh, Pomona, Port Charlotte, Richmond, Riverhead, Riverview, Rochester, Saint Augustine, Salisbury, Salt Lake City, San Antonio, San Bernardino, San Diego, San Marcos, Santa Rosa, Saratoga Springs, Savannah, Scottdale, Shavano Park, Sherman, Shreveport, Slidell, Smithfield, Somerset, Stamford, Stephenville, St Louis, St. Petersburg, Sun City West, Tacoma, Tempe, Thomasville, Tomball, Topeka, Torrance, Troy, Tucker, Tucson, Union, Uniontown, University Park, Vista, Waco, Wausau, Wauwatosa, Wellington, Weslaco, West Chester, Westfield, West Jordan, Westlake, West Monroe, West Seneca, Wichita, Wilmington, Winchester, Winston-Salem, Yardley, Yuma, Zachary
Age
18 years and over
People
11,800 worldwide
Run by
Boehringer Ingelheim
See details and how to joinNCT07064473 · EU 2025-521188-11-00
Phase 3Taking people
A Study to Evaluate Effect of AZD6234 in Adult Participants With Type 2 Diabetes Mellitus and Obesity or Overweight
Where
Ames, Bakersfield, Beltsville, Chicago, DeSoto, Doral, Eatontown, El Paso, Fairhope, Farmington Hills, Fayette, Fleming Island, Fort Lauderdale, Franklin, Gardena, Greensboro, Houston, Huntsville, Jackson, Kansas City, Knoxville, Lanham, Lenexa, Lincoln, Little Rock, Manassas, Melrose Park, Mesa, Midland, Mobile, Monroe, Newton, Norfolk, North Dartmouth, Oak Brook, Ocoee, Omaha, Oxon Hill, Pasadena, Phoenix, Rockville, San Antonio, Scottdale, Somerset, St Louis, Stow, Torrance, Tucson, Walnut Creek, Warren Township, Woodstock
Age
18 years and over
People
1,500 worldwide
Run by
AstraZeneca
See details and how to joinNCT07784270
Phase 2Taking people
Study to Assess the Effects of ALN-ANG3 in Adult Participants With Diabetic Kidney Disease
Where
Ann Arbor, Arlington, Bethlehem, Binghamton, Chattanooga, Chicago, City of Saint Peters, Dallas, DeSoto, Doral, El Paso, Greenville, Hialeah, Hollywood, Houston, Huntington Beach, Huntsville, Kansas City, Katy, Las Vegas, Little Rock, Margate, McKinney, Miami, Miami Springs, Miramar, Monroe, New Bern, New Haven, Northridge, Omaha, Orlando, Oxnard, Pembroke Pines, Pontiac, Port Orange, Port Saint Lucie, Salinas, San Antonio, San Dimas, Santa Clarita, Savannah, Spokane, Tamarac, Tarzana, The Bronx, Valencia, Victorville, West Chester, West Palm Beach, Winston-Salem
Age
18 years to 80 years
People
195
Run by
Regeneron Pharmaceuticals
See details and how to joinNCT07271186 · EU 2026-527519-41-00
No phaseEnrolling by invitation
MTM2MTG Pilot Ancillary Study
Where
New York
Age
20 years and over
People
80
Run by
Columbia University
See details and how to joinNCT07620808