Type 2 diabetes trials in United States

In United States 389 Also abroad 1200

389 trials · From ClinicalTrials.gov, checked 12 November 2026. Ask the study team whether a trial fits you.

Phase 3Taking people
A Safety, Tolerability, and Efficacy Study of VX-880 and VX-017 in Participants With Type 1 Diabetes
Where
Baltimore, Boston, Chicago, Dallas, Duarte, Madison, Miami, Philadelphia, Pittsburgh, Richmond, San Francisco
Age
18 years to 65 years
People
57 worldwide
Run by
Vertex Pharmaceuticals Incorporated
See details and how to joinNCT04786262 · EU 2024-513929-23-00
No phaseNot yet taking people in United States
Ability of Almonds to Improve Nutrition During GLP-1 Treatment
Where
Baton Rouge
Age
18 years to 70 years
People
76
Run by
Pennington Biomedical Research Center
See details and how to joinNCT07796204
Phase 3Taking people
AMBITION 7: A Research Study Investigating How Well Zenagamtide Lowers Blood Sugar and Body Weight Compared to Insulin Glargine in People With Type 2 Diabetes and Increased Risk of Diseases That Affect the Heart and Blood Vessels Treated With 1-3 Other Diabetes Medications
Where
Albany, Amarillo, Austin, Baltimore, Beaver, Birmingham, Boston, Bountiful, Bristol, Cincinnati, Clearwater, Conroe, Cordele, Corpus Christi, Council Bluffs, Covington, Crystal River, Dallas, Delray Beach, Detroit, Fairhope, Flint, Fort Mill, Fort Worth, Franklin, Greenfield, Gurnee, Hazel Crest, Hollywood, Houston, Idaho Falls, Iowa City, Jacksonville, Kansas City, Katy, Knoxville, Lakeland, Lancaster, Las Vegas, Layton, Lexington, Lincoln, Lomita, Longview, Los Alamitos, Los Angeles, Lufkin, Manassas, Manlius, Maumee, Mesquite, Miami, Miami Lakes, Miramar, Montgomery, Morehead City, Mt. Pleasant, Muncie, Myrtle Beach, Nashville, Newport, New Port Richey, New Windsor, New York, Norman, Northridge, Oak Brook, Ocala, Omaha, Palm Harbor, Pembroke Pines, Peoria, Richmond, Saint Augustine, Salem, Salt Lake City, San Antonio, San Diego, San Dimas, Scottsdale, Spring Valley, Statesville, St Louis, Sugar Land, The Bronx, Topeka, Troy, Tucker, Weslaco, West Des Moines, West Seneca, Winchester, Winston-Salem, Ypsilanti
Age
45 years and over
People
1,778 worldwide
Run by
Novo Nordisk A/S
See details and how to joinNCT07797335
Phase 3Taking people
A Phase III Study to Investigate the Efficacy and Safety of Elecoglipron Alone or in Combination With Dapagliflozin Compared With Placebo in Adults With Type 2 Diabetes Mellitus
Where
Anderson, Birmingham, Bowie, Bridgeport, Conyers, Covington, Daphne, Decatur, El Dorado, Englewood, Fort Worth, Hinesville, Irving, Jacksonville, Kansas City, Knoxville, Las Vegas, Lexington, Lomita, Los Alamitos, Newton, Orlando, Renton, San Diego, Southfield, St Louis, Walnut Creek
Age
18 years and over
People
800 worldwide
Run by
AstraZeneca
See details and how to joinNCT07662044 · EU 2025-523936-37-00
No phaseTaking people
Safety Evaluation of MODI, an Insulin Titration Algorithm, in Adults With Diabetes
Where
Albany, Austin, Baltimore, Detroit, Morehead City, Sandy City
Age
18 years to 80 years
People
102
Run by
DreaMed Diabetes
See details and how to joinNCT07599982
Phase 2Not yet taking people in United States
HMB Plus Vitamin D to Preserve Muscle in Older Adults Starting Semaglutide
Where
Nashville
Age
65 years to 85 years
People
90
Run by
Vanderbilt University Medical Center
See details and how to joinNCT07760948
No phaseNot yet taking people in United States
HOPE Intervention for Fitness
Where
Irvine
Age
18 years and over
People
120
Run by
University of California, Irvine
See details and how to joinNCT07114822
No phaseEnrolling by invitation
Feasibility of a Diabetes Self-Management Program With Continuous Glucose Monitoring for Adults With Type 2 Diabetes
Where
Manhasset
Age
18 years and over
People
20
Run by
Northwell Health
See details and how to joinNCT07743307
No phaseTaking people
Brown Adipose Tissue Activation by Spinal Cord Stimulation
Where
Portland
Age
21 years to 70 years
People
10
Run by
Oregon Health and Science University
See details and how to joinNCT04326192
No phaseTaking people
A Study to Identify and Characterize Patients With Type 2 Diabetes Mellitus for Possible Participation in Ongoing or Future Type 2 Diabetes Mellitus Clinical Studies
Where
Decatur, El Dorado, Gaffney, Jacksonville, Lake City, Leesburg, Lincoln, Little Rock, Maumee, Melrose Park, Ocoee, Peoria, Potomac, Renton
Age
18 years and over
People
2,150 worldwide
Run by
AstraZeneca
See details and how to joinNCT07606066
No phaseEnrolling by invitation
Liver Transplant CGM
Where
New York
Age
18 years and over
People
40
Run by
Icahn School of Medicine at Mount Sinai
See details and how to joinNCT07216508
No phaseTaking people
Lean Beef as Part of a Healthy Meal Plan in Adolescents With Polycystic Ovary Syndrome (PCOS)/Polyendocrine Metabolic Ovarian Syndrome (PMOS)
Where
College Station
Age
11 years to 17 years
People
36
Run by
Texas A&M University
See details and how to joinNCT07780188
No phaseTaking people
APP-MNT: App-Enhanced Medical Nutrition Therapy on Glycemic Outcomes and Quality of Life
Where
New York
Age
18 years to 75 years
People
52
Run by
Weill Medical College of Cornell University
See details and how to joinNCT07773779
Phase 3Taking people
Vitamin D and Type 2 Diabetes - Treat-To-Target
Where
Boston
Age
30 years to 74 years
People
100
Run by
Tufts Medical Center
See details and how to joinNCT07448974
No phaseTaking people
Specimen and Data Collection in South Carolina Medicaid-Enrolled Patients With Type 2 Diabetes (T2D) and Metabolically Healthy Controls
Where
Orangeburg, Walhalla
Age
40 years to 70 years
People
1,200
Run by
Guardian Research Network, Inc.
See details and how to joinNCT07731399
Phase 4Taking people
Quantifying Hepatic Mitochondrial Fluxes in Humans
Where
San Antonio
Age
18 years to 80 years
People
60
Run by
The University of Texas Health Science Center at San Antonio
See details and how to joinNCT05305287
No phaseEnrolling by invitation
Study to Understand Risk Information to Support and Empower
Where
Pleasanton
Age
18 years and over
People
2,000
Run by
University of California, Davis
See details and how to joinNCT05752292
No phaseTaking people
Diabetes Multimorbidity Typology, Trajectory, and Feasibility of an Audio Diary Mobile Application to Support Self-management
Where
Atlanta
Age
65 years and over
People
30
Run by
Emory University
See details and how to joinNCT07474376
No phaseEnrolling by invitation
Cardiometabolic Impact of a Produce Prescription Program in Patients With Type 2 Diabetes and Food Insecurity
Where
Morgantown
Age
18 years and over
People
88
Run by
West Virginia University
See details and how to joinNCT07674979
No phaseTaking people
NOURISH - A Healthcare-community Partnership to Improve Nutrition for Optimal Glycemic Control and Pregnancy Outcomes With Pregestational Diabetes
Where
Columbus
Age
18 years and over
People
174
Run by
Ohio State University
See details and how to joinNCT07560813
No phaseTaking people
Real World Evidence Clinical Utility Study of KidneyIntelX
Where
New York
Age
23 years and over
People
10,000
Run by
Renalytix AI, Inc.
See details and how to joinNCT04802395
No phaseNot yet taking people in United States
Adaptive Dietary Intervention (ADI) for Asian Americans With Type 2 Diabetes
Where
New York
Age
18 years and over
People
120
Run by
NYU Langone Health
See details and how to joinNCT07278531
Phase 4Taking people
Effect of Exercise and/or Liraglutide on Vascular Dysfunction and Insulin Sensitivity in Type 2 Diabetes ( ZQL007)
Where
Charlottesville
Age
21 years to 60 years
People
60
Run by
University of Virginia
See details and how to joinNCT03883412
No phaseTaking people
Acute Exercise and Endogenous Glucose Production in Type 2 Diabetes: Implications for Glycemic Control and Treatment of Hepatic Steatosis
Where
Orlando
Age
25 years to 55 years
People
12
Run by
AdventHealth Translational Research Institute
See details and how to joinNCT06993454
Phase 1Taking people
A Study to Investigate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD4248 in Healthy Participants and Participants With Chronic Kidney Disease and Type 2 Diabetes and to Assess Home Measurements of Creatinine in a Non Interventional Cohort
Where
Ann Arbor, Chicago, Glendale, Saint Paul, San Antonio
Age
18 years to 75 years
People
124
Run by
AstraZeneca
See details and how to joinNCT07024823