Type 2 diabetes trials in United States

In United States 393 Also abroad 1196

393 trials · From ClinicalTrials.gov, checked 10 November 2026. Ask the study team whether a trial fits you.

No phaseNot yet taking people in United States
Remotely Delivered Mindfulness-Based Diabetes Education
Where
Birmingham
Age
19 years and over
People
80
Run by
University of Alabama at Birmingham
See details and how to joinNCT06312553
Phase 2Not yet taking people in United States
Mitigating DKA in Type 1 Diabetes for Safe Use of SGLT Inhibitors Using Dual Continuous Ketone and Glucose Monitoring.
Where
Minneapolis
Age
18 years to 75 years
People
80
Run by
HealthPartners Institute
See details and how to joinNCT07325201
Phase 3Taking people
A Study to Find Out if the Study Drug Elecoglipron Helps Adults With Type 2 Diabetes Mellitus by Comparing it With Semaglutide, a Medicine Already Used to Treat Type 2 Diabetes Mellitus
Where
Albuquerque, Ames, Birmingham, Bountiful, Bowling Green, Bridgeport, Columbus, Covina, Crystal River, Dallas, Durham, Encinitas, Evansville, Falls Church, Feasterville-Trevose, Garden Grove, Henderson, Hollywood, Houston, Idaho Falls, Jacksonville, Jefferson City, Kansas City, Katy, Lake City, Las Vegas, Leesburg, Lilburn, Loma Linda, Long Beach, Melrose Park, Memphis, Mesa, Minneapolis, Morehead City, Morgantown, Morristown, Myrtle Beach, Norfolk, North Charleston, Oklahoma City, Omaha, Orlando, Philadelphia, Phoenix, Pomona, Raleigh, Renton, Rockville, Sacramento, Salt Lake City, San Antonio, Seattle, Southfield, Statesville, Sugar Land, Tempe, Weslaco, Wichita, Wilmington
Age
18 years and over
People
1,200 worldwide
Run by
AstraZeneca
See details and how to joinNCT07662213 · EU 2025-523933-24-00
No phaseNot yet taking people in United States
Scaling up the DSMES Learning Collaborative
Where
Lexington
Age
18 years to 99 years
People
96
Run by
Mary Lacy
See details and how to joinNCT07888179
No phaseNot yet taking people in United States
Transitioning Recently Admitted Patients With Non-Insulin and Insulin-treated Type 2 Diabetes to Innovative Glucose Monitoring
Where
Cincinnati
Age
18 years and over
People
218
Run by
University of Cincinnati
See details and how to joinNCT07890818
No phaseTaking people
Achieving Routine Intervention and Screening for Emotional Health
Where
Chicago
Age
18 years and over
People
880
Run by
University of Chicago
See details and how to joinNCT06887049
No phaseTaking people
New T-UP: Engaging Vulnerable Students in Diabetes Prevention
Where
Los Angeles
Age
17 years to 25 years
People
80
Run by
University of California, Los Angeles
See details and how to joinNCT07225218
Phase 1/2Taking people
Denosumab for Type 1 Diabetes
Where
Birmingham, Duarte, Indianapolis
Age
18 years to 50 years
People
45
Run by
City of Hope Medical Center
See details and how to joinNCT06524960
Phase 2Taking people
A Study to Evaluate ALN-4324 on Insulin Sensitivity in Adults With Type 2 Diabetes Mellitus
Where
Chula Vista
Age
18 years to 65 years
People
24
Run by
Alnylam Pharmaceuticals
See details and how to joinNCT07465224
Phase 2Taking people
Phase 2 Trial of Icovamenib in Participants With Type 2 Diabetes Mellitus Who Are Not Achieving Glycemic Targets While Using GLP-1-Based Therapy
Where
Austin, Birmingham, Burke, Canoga Park, Canton, Columbus, Cordele, Dallas, Fort Myers, Houston, Las Vegas, Lewisville, Long Beach, Miami Lakes, Missouri City, Montclair, Morehead City, San Antonio, San Diego, Winter Park
Age
18 years to 75 years
People
60
Run by
Biomea Fusion Inc.
See details and how to joinNCT07502508
Phase 3Taking people
A Study of Aleniglipron in Adults With Obesity or Overweight and Type 2 Diabetes Mellitus (ACCOMPLISH-2)
Where
Albany, Atlanta, Austin, Birmingham, Brooklyn, Burke, Chandler, Charlotte, Chesterfield, City of Saint Peters, Clearwater, Columbus, Des Moines, Durham, Escondido, Farmers Branch, Fayetteville, Fort Myers, Fountain Valley, Greer, Gulfport, Hazelwood, Houston, Iowa City, Jacksonville, La Jolla, Lake Forest, Las Vegas, Lawrenceville, Leesburg, Little Rock, Manassas, Mankato, Meridian, Methuen, Miami, Minneapolis, Missoula, Moore, Morehead City, Nashville, Ocala, Ocoee, Omaha, Pembroke Pines, Philadelphia, Phoenix, Portland, Renton, Ridgeland, Rolling Hills Estates, Salt Lake City, San Antonio, San Diego, Silver Spring, Springfield, St Louis, Suffolk, Sun City West, The Bronx, Tucson, Tulsa, Tustin, Union City, Waterbury, Wichita, Winston-Salem, Woodstock, Wylie, Yukon
Age
18 years to 79 years
People
1,100
Run by
Gasherbrum Bio, Inc., a wholly owned subsidiary of Structure Therapeutics
See details and how to joinNCT07654374
Phase 2Taking people
A Study Evaluating the Safety of Inavolisib and Fulvestrant With or Without Palbociclib in Participants With Advanced Breast Cancer (ABC) and Type 2 Diabetes
Where
Atlanta, Grand Island, Mineola, Morgantown, New York, Omaha, Washington D.C.
Age
18 years and over
People
40 worldwide
Run by
Hoffmann-La Roche
See details and how to joinNCT07748208
No phaseTaking people
Evaluation of MiniMed Next Generation Extended Wear Sensors and Algorithm in Patients With Type 1 and Type 2 Diabetes
Where
Atlanta, Aurora, Austin, Charlottesville, Chula Vista, Gainesville, Idaho Falls, New Haven, Palo Alto, Renton, San Antonio, San Diego, San Francisco, Santa Barbara, Seattle, Tampa, Walnut Creek
Age
2 years to 80 years
People
1,500
Run by
Medtronic MiniMed, Inc.
See details and how to joinNCT07864168
Phase 1Not yet taking people in United States
A Study of LY4167586 in Participants With Obesity or Overweight With or Without Type 2 Diabetes
Where
Anaheim, Columbus, Dallas, Daytona Beach, Decatur, Los Alamitos, Marlton, Miami, San Antonio, Walnut Creek, Winter Park
Age
18 years to 65 years
People
617 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT07881887
Phase 2Taking people
The Effect of Glycemic Control and of GLP-1 Receptor Agonism on Islet GLP-1 in People With Type 1 and Type 2 Diabetes
Where
Rochester
Age
25 years to 70 years
People
60
Run by
Mayo Clinic
See details and how to joinNCT06976619
No phaseEnrolling by invitation
Continued Access to the Endogenex System for Participants in the ReCET Pivotal Study
Where
Austin, Houston, Miami, New Brunswick, Orlando, Quincy, Raleigh
Age
22 years and over
People
50 worldwide
Run by
Endogenex, Inc.
See details and how to joinNCT07197788
Phase 3Taking people
A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Placebo in Children and Adolescents With Type 2 Diabetes
Where
Boynton Beach, Buffalo, Charlottesville, Columbus, Houston, Indianapolis, Iowa City, Jacksonville, Kissimmee, Memphis, New Haven, New York, Philadelphia, Rapid City, Seattle, Shavano Park, Snellville, Southfield, Springfield, Tamarac, Tampa
Age
10 years to 18 years
People
80 worldwide
Run by
Novo Nordisk A/S
See details and how to joinNCT07282613
Phase 2Taking people
Study to Evaluate HM15275 in Subjects With Type 2 Diabetes Mellitus
Where
Chicago, Columbus, DeLand, Fremont, Jefferson City, Kansas City, Las Vegas, Manassas, Mesa, Morehead City, Orlando, Salt Lake City, Santa Clarita, South Bend, The Villages, Tomball
Age
18 years to 75 years
People
180
Run by
Hanmi Pharmaceutical Company Limited
See details and how to joinNCT07527650
No phaseNot yet taking people in United States
Nutrition Intervention Optimization to Better Utilize Resources and Support Health
Where
Dallas
Age
18 years and over
People
400
Run by
Tufts University
See details and how to joinNCT07713836
No phaseTaking people
ENLIGHT Trial: ESG With Fundal Mucosal Ablation
Where
Morgantown
Age
18 years and over
People
62
Run by
West Virginia University
See details and how to joinNCT07792226
No phaseNot yet taking people in United States
Tracking Income Dynamics and Everyday Health Study
Where
Philadelphia
Age
50 years and over
People
400
Run by
University of Pennsylvania
See details and how to joinNCT07862452
No phaseTaking people
PreventT2 Together: Examining the Efficacy of Couple-based Lifestyle Intervention to Prevent Type 2 Diabetes
Where
Salt Lake City
Age
18 years and over
People
324
Run by
University of Utah
See details and how to joinNCT06690788
Phase 1/2Taking people
A Randomized Phase 1/2 Trial of Low Dose Anti-thymocyte Globulin (ATG) With Subsequent Adalimumab or Verapamil in New Onset Type 1 Diabetes
Where
Buffalo, Gainesville, Houston, Indianapolis, Los Angeles, Miami, Minneapolis, New Haven, Pittsburgh, San Francisco, Seattle
Age
9 years to 20 years
People
120
Run by
City of Hope Medical Center
See details and how to joinNCT07061574
No phaseEnrolling by invitation
PLAY2CONTROL Study
Where
Miami
Age
5 years to 21 years
People
30
Run by
University of Miami
See details and how to joinNCT07556679
Phase 1Taking people
A Research Study Investigating How Adults With Overweight or Obesity, With or Without Type 2 Diabetes, Tolerate Switching to a New Treatment (Zenagamtide) From Their Current Semaglutide Medication
Where
Baltimore, Glendale
Age
18 years and over
People
60
Run by
Novo Nordisk A/S
See details and how to joinNCT07855133