Ulcerative colitis trials in Spain

In Spain 26 Also abroad 382

26 trials · From ClinicalTrials.gov and EU CTIS (euclinicaltrials.eu), checked 10 November 2026. Ask the study team whether a trial fits you.

Phase 2Taking people
An Adaptive, Dose-Ranging, Phase 2 Study of Eltrekibart Given Alone or in Combination with Mirikizumab for the Treatment of Adult Patients with Moderately to Severely Active Ulcerative Colitis
Where
Barcelona, Córdoba, Huelva, Las Palmas De Gran Canaria, Madrid, Santiago de Compostela, Sevilla, Tomelloso, Valencia
Age
18 years and over
People
593 worldwide
Run by
Eli Lilly & Co.
See details and how to join2023-507853-13-00 · EU 2023-507853-13-00
Phase 2Enrolling by invitation
Long-term Safety and Efficacy of Multiple Long-acting Antibodies Alone and in Combinations for IBD
Where
Gijón, Lugo, Madrid, Majadahonda, Ourense, Santiago de Compostela, Sevilla
Age
18 years and over
People
645 worldwide
Run by
Spyre Therapeutics, Inc.
See details and how to joinNCT07652294 · EU 2025-524640-35-00
Phase 3Taking people
Mirikizumab Administered at the Same Time as Tirzepatide in Adult Participants With Moderately to Severely Active Ulcerative Colitis and Obesity or Overweight: Phase 3b Study
Where
Barcelona, Ferrol, Gijón, Madrid, Oviedo, Pamplona, Seville, Valencia
Age
18 years to 70 years
People
350 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT06937086 · EU 2024-520209-38-00
Phase 2Taking people
LY4268989 (MORF-057) Co-Administered With Mirikizumab in Adults With Moderately to Severely Active Ulcerative Colitis:
Where
Barcelona, Fuenlabrada, Gijón, Madrid
Age
18 years to 80 years
People
252 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT07186101
Phase 3Taking people
A Long-term Extension (LTE) Study of Guselkumab in Pediatric Participants
Where
Santiago de Compostela, Valencia
Age
3 years to 64 years
People
196 worldwide
Run by
Janssen Research & Development, LLC
See details and how to joinNCT06663332 · EU 2023-509560-16-00
Phase 3Taking people
A Study of JNJ-78934804 in Participants With Moderately to Severely Active Ulcerative Colitis
Where
Alicante, Madrid, Santiago de Compostela, Sevilla, Vigo, Zaragoza
Age
18 years and over
People
644 worldwide
Run by
Janssen Research & Development, LLC
See details and how to joinNCT07577856 · EU 2026-525923-26-00
No phaseNot yet taking people in Spain
A Real-World Study of Guselkumab Persistence and Effectiveness in Participants With Crohn's Disease or Ulcerative Colitis
Where
Santiago de Compostela
Age
18 years and over
People
200
Run by
Janssen-Cilag, S.A.
See details and how to joinNCT07848737
Phase 4Taking people
A study to measure mirikizumab levels in breast milk of lactating participants receiving mirikizumab therapeutically for an approved indication
Where
Madrid
People
16 worldwide
Run by
Eli Lilly & Co.
See details and how to join2025-522362-78-00 · EU 2025-522362-78-00
Phase 1/2Taking people
Study of XmAb942 in Healthy Participants and Participants With Ulcerative Colitis
Where
Barcelona, Valencia
Age
18 years to 75 years
People
270 worldwide
Run by
Xencor, Inc.
See details and how to joinNCT06619990
Phase 2Taking people
A Study to Evaluate Etrasimod Treatment in Adolescents With Ulcerative Colitis
Where
Barcelona, Córdoba, Sabadell, Santiago de Compostela
Age
12 years to 17 years
People
36 worldwide
Run by
Pfizer
See details and how to joinNCT05287126 · EU 2022-500345-25-00
Phase 2Taking people
A Study of Long-acting Antibodies Alone and in Combinations for Moderate to Severe Ulcerative Colitis
Where
Gijón, Lugo, Madrid, Majadahonda, Ourense, Santiago de Compostela, Sevilla
Age
18 years to 75 years
People
645 worldwide
Run by
Spyre Therapeutics, Inc.
See details and how to joinNCT07012395 · EU 2025-521242-26-00
Phase 3Taking people
A Study to Learn More About How Risankizumab Works in Young Participants With Ulcerative Colitis
Where
A Coruña, Majadahonda
Age
2 years to 17 years
People
120 worldwide
Run by
AbbVie
See details and how to joinNCT07071519 · EU 2024-514695-41-00
Phase 3Taking people
A study evaluating the effects of filgotinib in children and teenagers with ulcerative colitis
Where
Badalona, Córdoba
Age
Up to 17 years
People
68 worldwide
Run by
Alfasigma S.p.A.
See details and how to join2024-511458-32-00 · EU 2024-511458-32-00
Phase 2/3Taking people
A Study Investigating Oral Ozanimod (RPC1063) in Pediatric Participants With Moderate to Severe Active Ulcerative Colitis
Where
Badalona, Esplugues de Llobregat, Madrid
Age
2 years to 17 years
People
120 worldwide
Run by
Bristol-Myers Squibb
See details and how to joinNCT05076175
Phase 3Taking people
A Study Evaluating the Effects of Filgotinib in Children and Teenagers With Ulcerative Colitis
Where
Badalona, Córdoba
Age
8 years to 18 years
People
80 worldwide
Run by
Alfasigma S.p.A.
See details and how to joinNCT06865417
Phase 3Taking people
A Maintenance Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Ulcerative Colitis
Where
Huelva
Age
16 years to 80 years
People
751 worldwide
Run by
Sanofi
See details and how to joinNCT07185009
Phase 3Taking people
A Long-Term Extension Study of Vedolizumab in Children and Teenagers With Ulcerative Colitis (UC) or Crohn's Disease (CD)
Where
Ferrol, Madrid, Sevilla, Valencia
Age
2 years to 17 years
People
70 worldwide
Run by
Takeda
See details and how to joinNCT06405087 · EU 2023-508804-39-00
Phase 2Taking people
LY4268989 (MORF-057) Co-Administered with Mirikizumab in Adults with Moderately to Severely Active Ulcerative Colitis: A Phase 2 Study
Where
Barcelona, Fuenlabrada, Gijón, Madrid, Santa Cruz de Tenerife
Age
18 years and over
People
75 worldwide
Run by
Eli Lilly & Co.
See details and how to join2025-522338-30-00 · EU 2025-522338-30-00
Phase 3Taking people
A Master Protocol (AMAZ): A Study of Mirikizumab (LY3074828) in Pediatric Participants With Ulcerative Colitis or Crohn's Disease (SHINE-ON)
Where
Córdoba, Esplugues de Llobregat, Sabadell, Valencia
Age
2 years to 19 years
People
150 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT04844606
Phase 3Taking people
A Study of Vedolizumab in Children and Teenagers With Ulcerative Colitis or Crohn's Disease
Where
Ferrol, Madrid, Sevilla, Valencia
Age
2 years to 17 years
People
70 worldwide
Run by
Takeda
See details and how to joinNCT06100289 · EU 2023-503188-40-00
Phase 2/3Taking people
A phase 2/3, multicenter, randomized, double-blind study to evaluate the efficacy, safety, pharmacokinetics and pharmacodynamics of oral ozanimod (RPC1063) in pediatric subjects with moderately to severely active ulcerative colitis with an inadequate response to conventional therapy.
Where
Badalona, Esplugues De Llobregat, Madrid
Age
Up to 17 years
People
62 worldwide
Run by
Bristol-Myers Squibb Services Unlimited Company
See details and how to join2023-509248-86-00 · EU 2023-509248-86-00
Phase 3Taking people
A Study of Vedolizumab in Children With Ulcerative Colitis (UC) or Crohn's Disease (CD)
Where
Barcelona, Madrid, Málaga, Sagunto, Seville
Age
2 years to 17 years
People
240 worldwide
Run by
Takeda
See details and how to joinNCT05442567 · EU 2023-509046-36-00
No phaseTaking people
Immunological Characteristics of Preclinical IBD
Where
Alicante, Badalona, Barcelona, Bilbao, Burgos, Córdoba, Donostia / San Sebastian, Galdakao, Gijón, Madrid, Manresa, Ourense, Oviedo, San Cristóbal de La Laguna, Santiago de Compostela, Terrassa, Valencia, Valladolid, Vigo, Zaragoza
Age
18 years and over
People
450
Run by
Grupo Espanol de Trabajo en Enfermedad de Crohn y Colitis Ulcerosa
See details and how to joinNCT05698745
Phase 4Not yet taking people in Spain
Immunosuppressant Discontinuation in Elderly Patients With Ulcerative Colitis And Long-term Remission
Where
Badalona, Barcelona, Burgos, Girona, Madrid, Mataro, Motril, Ourense, Sabadell, Santander, Santiago de Compostela, Sevilla, Terrassa, Vigo, Zaragoza
Age
60 years and over
People
304
Run by
Grupo Espanol de Trabajo en Enfermedad de Crohn y Colitis Ulcerosa
See details and how to joinNCT07248644 · EU 2025-524675-23-00
No phaseEnrolling by invitation
Effectiveness of Health Education as a Nursing Intervention in Improving Quality of Life and Reducing Symptoms of Anxiety and Depression in Ostomy Patients Following Digestive Surgery: A Quasi-Experimental Study.
Where
Santiago de Compostela
Age
18 years and over
People
70
Run by
Hospital Clinico Universitario de Santiago
See details and how to joinNCT07347158