Clinical trials

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500 trials

NCT05703685
Recruiting
[18F]PF-06445974 to Image PDE4B in Major Depressive Disorder Using PET
Phase 1 · United States · 1 site
Registry update: 1 Oct 2026
NCT05922878
Recruiting
Study of ALTO-300 in MDD
Phase 2 · United States · 74 sites
Registry update: 26 Oct 2026
NCT05703256
Recruiting
Amygdala Neurofeedback for Depression - Large Scale Clinical Trial
Not applicable · United States · 1 site
Registry update: 4 Mar 2026
NCT06085950
Recruiting
Transcranial Ultrasonic Stimulation in Treatment-resistant Depression : an Open-label Pilot Trial
Not applicable · France · 1 site
Registry update: 22 Jun 2026
NCT05850689
Recruiting
Study of Lumateperone as Adjunctive Therapy in the Treatment of Patients With Major Depressive Disorder
Phase 3 · Bulgaria, Spain, France, India, Lithuania, Serbia, United States · 69 sites
Registry update: 3 Nov 2026
NCT05833087
Recruiting
Schema Therapy for Patients With Chronic Treatment Resistant Depression
Not applicable · Denmark · 6 sites
Registry update: 23 Sept 2025
NCT05786066
Recruiting
The Impact of AMPA Receptor Blockade on Ketamine's Anti-Suicidal Effects
Phase 2 · United States · 1 site
Registry update: 6 May 2026
NCT05573074
Recruiting
Transcranial Near Infrared Radiation and Cerebral Blood Flow in Depression - R33
Not applicable · United States · 3 sites
Registry update: 5 Feb 2026
NCT07002684
Recruiting
Metabolic Profiling of Esketamine Treatment in Depressive Disorder
Not applicable · Croatia · 1 site
Registry update: 3 Jun 2025
NCT06823492
Recruiting
Investigating the Impacts of Early Life Experience on the Brain & Behaviour
Not applicable · United Kingdom · 1 site
Registry update: 12 Feb 2025
NCT05051618
Recruiting
Exercise Training for Managing Major Depressive Disorder in Multiple Sclerosis
Not applicable · United States · 1 site
Registry update: 4 Jun 2026
NCT05435222
Recruiting
Evaluation of a Male-specific Psychotherapeutic Program for Major Depressive Disorders
Not applicable · Switzerland · 1 site
Registry update: 28 Mar 2025
NCT05725239
Recruiting
taVNS or TMS or Both for Depression
Not applicable · United States · 1 site
Registry update: 12 Aug 2026
NCT05423275
Recruiting
Light and Ion Maintenance In Treatment for Depression (LIMIT-D): Feasibility Study
Not applicable · Canada · 1 site
Registry update: 9 Dec 2024
NCT05905705
Recruiting
Disruptions of Brain Networks and Sleep by Electroconvulsive Therapy
Not applicable · United States · 1 site
Registry update: 12 Mar 2026
NCT05570812
Recruiting
Neuroactive Steroid to Treat Depressed Mood: A Trial for People With HIV
Phase 2 · United States · 1 site
Registry update: 12 Sept 2025
NCT05773755
Recruiting
DBS for TRD With the Medtronic Percept PC
Not applicable · United States · 1 site
Registry update: 22 Sept 2026
NCT04556890
Recruiting
Pain and Major Depressive Disorder
Not applicable · United States · 1 site
Registry update: 11 Aug 2026
NCT05798143
Recruiting
Translational Biomarkers in Accelerated Neuromodulation for Treatment-resistant Depression
Not applicable · Italy · 1 site
Registry update: 4 Apr 2023
NCT05656469
Recruiting
Clinical Study Evaluating Pharmacogenomics-informed Pharmacotherapy Versus Dosing as Usual in Psychiatric Disorders
Phase 4 · Germany, Spain, United Kingdom, Netherlands, Romania, Serbia, United States · 8 sites
Registry update: 2 Jun 2026

Ordered by registry start date. Freshness and sponsorship never change the order.