Written based on 13 research studies on PubMed, searched on 2026. nov. 11..
The claim
Posts online say that CBD (cannabidiol) helps with high blood pressure.
Where research stands
We found 19 published papers on CBD (cannabidiol) and high blood pressure. They were published between 2018 and 2026. 5 of them are studies in people. 5 of them compared people who got it with a group that did not. 12 were studies in animals, and none was only in cells in the lab. 2 research projects on CBD (cannabidiol) for high blood pressure are funded and still running.
- 5In people5 with a comparison group
- 12In animals
- 0Only in the lab
What the studies found
We have not summed up these studies in words yet. The most important papers are listed under Sources.
Verdict
CBD (cannabidiol) has been tested in randomised trials in people with high blood pressure.
What this means for you: A study in people is not proof that it helps you. Do not stop or change your medicines because of it. Ask your doctor before you start taking it.
Sources
- Chronic Cannabidiol Administration Mitigates Excessive Daytime Sleepiness and Fatigue in Patients with Primary Hypertension: Insights from a Randomized Crossover Trial.2025 · Cannabis Cannabinoid Res · Randomised trial
- Chronic Effects of Oral Cannabidiol Delivery on 24-h Ambulatory Blood Pressure in Patients with Hypertension (HYPER-H21-4): A Randomized, Placebo-Controlled, and Crossover Study.2024 · Cannabis Cannabinoid Res · Randomised trial
- Effects of CBD supplementation on ambulatory blood pressure and serum urotensin-II concentrations in Caucasian patients with essential hypertension: A sub-analysis of the HYPER-H21-4 trial.2023 · Biomed Pharmacother · Randomised trial
- The Influence of Oral Cannabidiol on 24-h Ambulatory Blood Pressure and Arterial Stiffness in Untreated Hypertension: A Double-Blind, Placebo-Controlled, Cross-Over Pilot Study.2023 · Adv Ther · Randomised trial
- CBD supplementation reduces arterial blood pressure via modulation of the sympatho-chromaffin system: A substudy from the HYPER-H21-4 trial.2023 · Biomed Pharmacother · Randomised trial
- The effects of chronic administration of Cannabidiol and Cannabidiol-Selexipag combination on haematological parameters, oxidative stress, BNP, and TNF-α in a rat model of Pulmonary Arterial Hypertension.2026 · Cardiovasc J Afr · In animals
- Chronic cannabidiol treatment induces cardiovascular improvement in renovascular hypertensive rats.2025 · J Hypertens · In animals
- Cannabidiol treatment changes myocardial lipid profile in spontaneously hypertensive rats.2024 · Nutr Metab Cardiovasc Dis · In animals
- Cannabidiol may prevent the development of congestive hepatopathy secondary to right ventricular hypertrophy associated with pulmonary hypertension in rats.2024 · Pharmacol Rep · In animals
- Cannabidiol alleviates right ventricular fibrosis by inhibiting the transforming growth factor β pathway in monocrotaline-induced pulmonary hypertension in rats.2023 · Biochim Biophys Acta Mol Basis Dis · In animals
- Cannabidiol inhibits lung proliferation in monocrotaline-induced pulmonary hypertension in rats.2023 · Biomed Pharmacother · In animals
- Geriatric Pharmacotherapy Case Series: Potential Drug Interactions With Antiplatelet Medications and Cannabidiol-A Focus on P2Y12 Inhibitors.2023 · Sr Care Pharm · Other paper
- Cannabidiol-Induced Acute Generalized Exanthematous Pustulosis.2018 · Dermatitis · Other paper
