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Stem cell treatment & High blood pressure

Checked 2026. nov. 11. · High blood pressure

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Written based on 20 research studies on PubMed, searched on 2026. nov. 11..

The claim

Posts online say that stem cell treatment helps with high blood pressure.

Where research stands

We found 125 published papers on stem cell treatment and high blood pressure. They were published between 1997 and 2026. 1 of them is a study in people. None of them compared people who got it with a group that did not. 47 were studies in animals, and 3 were only in cells in the lab. 43 papers are reviews that sum up other studies. 2 new studies in people are running or will start soon, say the trial registers. 34 research projects on stem cell treatment for high blood pressure are funded and still running.

  • 1In people
  • 47In animals
  • 3Only in the lab

What the studies found

We have not summed up these studies in words yet. The most important papers are listed under Sources.

Verdict

Stem cell treatment has been studied in people with high blood pressure, but not in randomised trials.

What this means for you: A study in people is not proof that it helps you. Do not stop or change your medicines because of it. Ask your doctor before you start taking it.

Sources

  1. Comorbid conditions after allogeneic haematopoietic stem cell transplantation in young adults in Germany-A prospective, multicentre trial.2026 · Br J Haematol · Study in people
  2. Mesenchymal stem cell therapy and gut microbiota modulation in preclinical disease models: a systematic review with implications for hypertension.2026 · Mol Biol Rep · Review
  3. Kidney and Blood Pressure Outcomes in Children Surviving at Least 6 Months after Hematopoietic Stem Cell Transplantation: A Systematic Review and Meta-Analysis.2026 · Transplant Cell Ther · Review
  4. Exploring the Potential of Stem Cells in Modulating Gut Microbiota and Managing Hypertension.2025 · Stem Cells Dev · Review
  5. Stem cells in pulmonary hypertension: Current understanding and future challenges.2024 · Animal Model Exp Med · Review
  6. Novel insights into the potential applications of stem cells in pulmonary hypertension therapy.2024 · Respir Res · Review
  7. Thrombotic Microangiopathy After Hematopoietic Stem Cell and Solid Organ Transplantation: A Review for Intensive Care Physicians.2024 · J Intensive Care Med · Review
  8. HO-1-modified umbilical cord MSCs alleviate pulmonary arterial hypertension by reducing inflammation and endothelial dysfunction.2026 · Stem Cells Transl Med · In animals
  9. Tracheal delivery of HO-1-modified human umbilical cord-derived mesenchymal stem cells treats pulmonary arterial hypertension by enhancing pulmonary antioxidant and anti-inflammatory responses.2026 · Transl Res · In animals
  10. Intervention effect of small extracellular vesicles derived from dental pulp stem cells on a high-altitude pulmonary edema model in male rats.2026 · Physiol Rep · In animals
  11. PM2.5 exposure induces functional alterations in pregnant rats heart and in human stem cell derived cardiac spheroids.2026 · Arch Toxicol · In animals
  12. Mitochondrial Transplantation from Bone Marrow Mesenchymal Stromal Cells Combined with Sildenafil Attenuated Vascular Remodeling and Improved Right Ventricular Dysfunction in Experimental Pulmonary Arterial Hypertension.2026 · Int J Mol Sci · In animals
  13. Mesenchymal stromal cells alleviate pulmonary arterial hypertension by suppressing pulmonary arterial adventitial fibroblast activation and extracellular matrix remodeling via the SOCS3/STAT3 pathway.2026 · Stem Cell Res Ther · In animals
  14. Generation of a human induced pluripotent stem cell line (UMGACBi001-A) from urine cells of a chronic kidney disease patient with hypertension, diabetic nephropathy and acute sepsis.2023 · Stem Cell Res · In the lab
  15. Generation of two induced pluripotent stem cell lines from patients suffering from pulmonary hypertension.2023 · Stem Cell Res · In the lab
  16. Derivation of an induced pluripotent stem cell line (PUMCHi003-A) from a patient with pulmonary arterial hypertension carrying heterozygous mutation in PTGIS gene.2020 · Stem Cell Res · In the lab
  17. Maternal Endocrine and Vascular Perturbations Reprogram the Transcriptomic and Secretory Profile of Perinatal Stem Cells: A Comparative Study of Umbilical Cord-Derived Stem Cell UC-MSCs and Human Milk-Derived Stem Cell MM-MSCs.2026 · Int J Mol Sci · Other paper
  18. A Complex Case of Systemic Sclerosis with Concurrent Breast Malignancy and Treatment-related Complications.2026 · J Assoc Physicians India · Other paper
  19. Long-Term Health Outcomes in Male Survivors of Childhood Cancer After Hematopoietic Stem Cell Transplantation: A Registry-Based Study.2026 · Pediatr Hematol Oncol · Other paper
  20. A 62-Year-Old Woman with Diarrhea after Hematopoietic Stem-Cell Transplantation.2025 · NEJM Evid · Other paper

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