Written from the studies on PubMed, searched on 2026. nov. 11.. Every number below comes from a study listed under Sources.
What people read
Posts online say that CBD (cannabidiol) helps with Migraine.
What has been studied
- 2In people1 randomised trial
- 3In animals
- 0Only in the lab
What the studies found
CBD (cannabidiol) has been tested in randomised trials in people with Migraine.
We found 7 published papers on CBD (cannabidiol) and Migraine. They were published between 2023 and 2025.
2 of them are studies in people (1 randomised trials), 1 are reviews, 3 are studies in animals and 0 are studies only in the lab.
The most important ones are listed under Sources.
What this means for you: A study in people is not proof that it helps you. Do not stop or change your medicines because of it. Ask your doctor before you start taking it.
Sources
- A multi-centre, tolerability study of a cannabidiol-enriched Cannabis Herbal Extract for chronic headaches in adolescents: The CAN-CHA protocol.2024 · PLoS One · Randomised trial
- Expanding the Therapeutic Profile of Topical Cannabidiol in Temporomandibular Disorders: Effects on Sleep Quality and Migraine Disability in Patients with Bruxism-Associated Muscle Pain.2025 · Pharmaceuticals (Basel) · Study in people
- Should CBD be used for migraine?2025 · JAAPA · Review
- Combined effects of cannabidiol and Δ9-tetrahydrocannabinol alleviate migraine-like symptoms in mice.2025 · Cephalalgia · In animals
- Preclinical effects of cannabidiol in an experimental model of migraine.2023 · Pain · In animals
- Characterization of the biochemical and behavioral effects of cannabidiol: implications for migraine.2023 · J Headache Pain · In animals
- Correction: Characterization of the biochemical and behavioral effects of cannabidiol: implications for migraine.2023 · J Headache Pain · Other paper