Written from the studies on PubMed, searched on 2026. nov. 11.. Every number below comes from a study listed under Sources.
What people read
Posts online say that Curcumin (turmeric) helps with Migraine.
What has been studied
- 14In people14 randomised trials
- 3In animals
- 0Only in the lab
What the studies found
Curcumin (turmeric) has been tested in randomised trials in people with Migraine.
We found 20 published papers on Curcumin (turmeric) and Migraine. They were published between 2017 and 2025.
14 of them are studies in people (14 randomised trials), 2 are reviews, 3 are studies in animals and 0 are studies only in the lab.
The most important ones are listed under Sources.
What this means for you: A study in people is not proof that it helps you. Do not stop or change your medicines because of it. Ask your doctor before you start taking it.
Sources
- Effect and Safety of Phytosomal Curcumin Supplementation on Migraine Patients: A Randomized, Double-Blind and Placebo-Controlled Trial.2025 · Chin J Integr Med · Randomised trial
- The effects of phytosomal curcumin supplementation on clinical symptoms, and inflammatory and oxidative stress biomarkers in patients with migraine: A protocol for a randomized double-blind placebo-controlled trial.2023 · Avicenna J Phytomed · Randomised trial
- The Effects of Nano-curcumin Supplementation on Leptin and Adiponectin in Migraine Patients: A Double-blind Clinical Trial Study from Gene Expression to Clinical Symptoms.2023 · Endocr Metab Immune Disord Drug Targets · Randomised trial
- The effects of nano-curcumin supplementation on Th2/tregulatory axis in migraine patients: a randomized, double-blind, placebo-controlled trial.2023 · Int J Neurosci · Randomised trial
- The effects of nano-curcumin supplementation on adipokines levels in obese and overweight patients with migraine: a double blind clinical trial study.2022 · BMC Res Notes · Randomised trial
- Effects of Curcumin Supplementation on Clinical Features and Inflammation, in Migraine Patients: A Double-Blind Controlled, Placebo Randomized Clinical Trial.2021 · Int J Prev Med · Randomised trial
- The omega-3 and Nano-curcumin effects on vascular cell adhesion molecule (VCAM) in episodic migraine patients: a randomized clinical trial.2021 · BMC Res Notes · Randomised trial
- Anti-Neuroinflammatory Properties of n-3 Fatty Acids and Nano- Curcumin on Migraine Patients from Cellular to Clinical Insight: A Randomized, Double-Blind and Placebo-Controlled Trial.2021 · Endocr Metab Immune Disord Drug Targets · Randomised trial
- The synergistic effects of nano-curcumin and coenzyme Q10 supplementation in migraine prophylaxis: a randomized, placebo-controlled, double-blind trial.2021 · Nutr Neurosci · Study in people
- The effects of nano-curcumin supplementation on Th1/Th17 balance in migraine patients: A randomized controlled clinical trial.2020 · Complement Ther Clin Pract · Study in people
- The impact of curcumin on migraine: A comprehensive review.2023 · Biomed Pharmacother · Review
- The clinical use of curcumin on neurological disorders: An updated systematic review of clinical trials.2021 · Phytother Res · Review
- Liposomal Curcumin Enhances the Effect of Naproxen in a Rat Model of Migraine.2019 · Med Sci Monit · In animals
- The effect of intravenous administration of liposomal curcumin in addition to sumatriptan treatment in an experimental migraine model in rats.2018 · Int J Nanomedicine · In animals
- Preemptive Analgesic and Antioxidative Effect of Curcumin for Experimental Migraine.2017 · Biomed Res Int · In animals
- The Effect of Nano-Curcumin Supplementation on Pentraxin 3 Gene Expression and Serum Level in Migraine Patients.2020 · Rep Biochem Mol Biol · Other paper