Written from the studies on PubMed, searched on 2026. nov. 11.. Every number below comes from a study listed under Sources.
What people read
Posts online say that Curcumin (turmeric) helps with ALS (motor neurone disease).
What has been studied
- 1In people1 randomised trial
- 3In animals
- 0Only in the lab
What the studies found
Curcumin (turmeric) has been tested in randomised trials in people with ALS (motor neurone disease).
We found 9 published papers on Curcumin (turmeric) and ALS (motor neurone disease). They were published between 2011 and 2025.
1 of them are studies in people (1 randomised trials), 2 are reviews, 3 are studies in animals and 0 are studies only in the lab.
The most important ones are listed under Sources.
What this means for you: A study in people is not proof that it helps you. Do not stop or change your medicines because of it. Ask your doctor before you start taking it.
Sources
- Amyotrophic Lateral Sclerosis and Oxidative Stress: A Double-Blind Therapeutic Trial After Curcumin Supplementation.2018 · CNS Neurol Disord Drug Targets · Randomised trial
- Benefits of curcumin in brain disorders.2019 · Biofactors · Review
- ALSUntangled 44: curcumin.2018 · Amyotroph Lateral Scler Frontotemporal Degener · Review
- Potential role of solid lipid curcumin particle (SLCP) as estrogen replacement therapy in mitigating TDP-43-related neuropathy in the mouse model of ALS disease.2025 · Exp Neurol · In animals
- Therapeutic effect of a novel curcumin derivative GT863 on a mouse model of amyotrophic lateral sclerosis.2022 · Amyotroph Lateral Scler Frontotemporal Degener · In animals
- Activation of nuclear factor erythroid 2-related factor 2 cytoprotective signaling by curcumin protect primary spinal cord astrocytes against oxidative toxicity.2011 · Biol Pharm Bull · In animals
- Mechanism of the interaction of toxic SOD1 fibrils with two potent polyphenols: curcumin and quercetin.2023 · Phys Chem Chem Phys · Other paper
- Curcumin and neurological diseases.2022 · Nutr Neurosci · Other paper
- Curcumin abolishes mutant TDP-43 induced excitability in a motoneuron-like cellular model of ALS.2014 · Neuroscience · Other paper