Új vizsgálatok, publikációk, preprintek és pályázatok ezen a célponton, hónapról hónapra.
Vizsgálat
Prizloncabtagene Autoleucel (Prizlon-cel) for the Treatment of Relapsed or Refractory Large B-cell Lymphoma Post FDA Approved CAR T-cell Therapy
2027. máj. 1.· PHASE2 · NOT_YET_RECRUITING· CTGOV
Vizsgálat
A Study of LP-118 In Combination With Ponatinib, Dexamethasone And Blinatumomab For Adults With Newly-Diagnosed, BCR::ABL1-Positive Acute Lymphoblastic Leukemia (ALL)
2026. dec. 1.· PHASE1 · RECRUITING· CTGOV
Vizsgálat
Nemtabrutinib for Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Leukemia (SLL) Refractory to Covalent Bruton Tyrosine Kinase Inhibitor or Pirtobrutinib and Previously Treated With a BCL2 Inhibitor
2026. nov. 11.· PHASE2 · NOT_YET_RECRUITING· CTGOV
Publikáció
Cytotoxic effects and modulation of BAX/BCL-2 gene expression induced by plant-derived cerium oxide nanoparticles in HepG2 cells.
2026. okt. 31.· Cytotechnology· PUBMED
Publikáció
Assessment of BCL-2 expression in bone marrow by flow cytometry to aid in the diagnosis and differential diagnosis in patients with follicular lymphoma.
2026. okt. 30.· Cytometry. Part B, Clinical cytometry· PUBMED
Publikáció
Dactolisib outperforms Rapamycin in potentiating apoptosis induced by XPO1, Bcl-2 and Mcl-1 blockade in preclinical glioblastoma models.
2026. okt. 24.· FEBS open bio· PUBMED
Publikáció
Gudan Wan attenuates metabolic dysfunction-associated steatohepatitis by modulating autophagy and the Bcl-2/Caspase-3/Caspase-8 apoptotic axis.
2026. okt. 22.· Frontiers in cell and developmental biology· PUBMED
Publikáció
Immunohistochemical Expression of M30, BCL-2, BAX, and Ki-67 in Pancreatic Ductal Adenocarcinoma: Association with Clinicopathological Features.
2026. okt. 21.· Diagnostics (Basel, Switzerland)· PUBMED
Publikáció
A Novel BCL2 Translocation and Concurrent Chromosome 13q14 Deletion in Chronic Lymphocytic Leukemia: A Case Report.
2026. okt. 18.· EJHaem· PUBMED
Publikáció
Engineered solid lipid-polymer hybrid nanoparticles for trackable co-delivery of glycoalkaloids and Bcl-2/CD146-targeting of siRNAs: A topical formulation strategy for melanoma.
2026. okt. 17.· Colloids and surfaces. B, Biointerfaces· PUBMED
Publikáció
Rational structure-guided identification of a Bcl-2-targeting peptide with antiproliferative effects on colorectal cancer cells.
2026. okt. 14.· Journal of enzyme inhibition and medicinal chemistry· PUBMED
Vizsgálat
A Phase II Study of TT-01488 Tablets in Combination With Anti-CD20 Monoclonal Antibody Therapy in Patients With Mantle Cell Lymphoma
2026. okt. 10.· PHASE2 · NOT_YET_RECRUITING· CTGOV
Publikáció
Retraction Note: Histone acetyltransferase PCAF accelerates apoptosis by repressing a GLI1/BCL2/BAX axis in hepatocellular carcinoma.
2026. okt. 8.· Cell death & disease· PUBMED
Publikáció
Enhanced Antileukemic Efficacy of Venetoclax-Loaded PEG-PLGA Nanoparticles Against THP-1 Acute Monocytic Leukemia Cells via Suppression of BCL-2 and Pro-Survival Signaling Pathways.
2026. okt. 6.· Biomedicines· PUBMED
Vizsgálat
Real-World Study of BCL-2 Inhibitor-Based Regimens in Chronic Lymphocytic Leukemia
2026. okt. 1.· NA · RECRUITING· CTGOV
Publikáció
Correction: The proapoptotic BCL-2 family member BIM mediates motoneuron loss in a model of amyotrophic lateral sclerosis.
2026. okt. 1.· Cell death and differentiation· PUBMED
Publikáció
Extranodal Organ Involvement in Chronic Lymphocytic Leukemia: Clinical Features and Outcomes With Bruton Tyrosine Kinase and BCL-2 Inhibitors.
2026. okt. 1.· Cancer medicine· PUBMED
Publikáció
Immunohistochemical expression of E-cadherin and Bcl-2 in oral squamous cell carcinoma.
2026. szept. 30.· Indian journal of cancer· PUBMED
Publikáció
Deciphering the clinical significance of Beclin-1 and Bcl-2 in urothelial carcinoma of bladder.
2026. szept. 29.· Indian journal of urology : IJU : journal of the Urological Society of India· PUBMED
Publikáció
BushenQiangxin Formula Inhibits Inflammation and Apoptosis in Doxorubicin- Induced Heart Failure via the NF-κB/Bcl-2 Axis.
2026. szept. 25.· Current drug metabolism· PUBMED
Publikáció
Combining the Telomerase Inhibitor Imetelstat with the BCL-2 Inhibitor Venetoclax Enhances Apoptosis and Improves Survival in Acute Myeloid Leukemia Cellular and Animal Models.
2026. szept. 23.· Journal of clinical medicine· PUBMED
Publikáció
Integrative Systems Biology Prioritizes BCL2, ALK, and CDK4 as Therapeutic Candidates in Neuroblastoma through Multi-Centrality Network Analysis, Cross-Database Validation, Independent Docking Validation, and Confidence-Threshold Sensitivity Analysis.
2026. szept. 21.· Computational biology and chemistry· PUBMED
Publikáció
RAS seals fate in AML besieged by FLT3 and BCL2 inhibitors.
2026. szept. 17.· Blood· PUBMED
Publikáció
Dynamic genetic and nongenetic RAS-pathway activation drives resistance to FLT3 and BCL2 inhibitor therapy.
2026. szept. 17.· Blood· PUBMED
Publikáció
GATA3-driven CDC20 activation facilitates tumor growth and metastasis through suppressing Bax/Bcl-2 ratio and boosting EMT process in neuroblastoma.
2026. szept. 12.· The Journal of biological chemistry· PUBMED
Publikáció
Impact of BCL-2 rs2279115 and rs3943258 variants on protein expression and clinical outcome of urothelial bladder carcinoma.
2026. szept. 7.· Molecular biology reports· PUBMED
Publikáció
Testicular aggressive B-cell lymphoma with plasmablastic morphology harboring concurrent IGH::MYC and IGH::BCL2 rearrangements.
2026. szept. 7.· Journal of hematopathology· PUBMED
Publikáció
CRC cell cycle arrest and early apoptosis induction by mononuclear octahedral cobalt(III) Schiff base through the inhibition of CDK4/6 and BCL2.
2026. szept. 5.· Medical oncology (Northwood, London, England)· PUBMED
Publikáció
Evaluation of Programmed Death Ligand-1 (PD-L1) and B-cell Lymphoma 2 (BCL2) protein expression using immunohistochemistry in colorectal carcinoma patients from Anbar Governorate.
2026. szept. 4.· Journal of the Egyptian National Cancer Institute· PUBMED
Publikáció
BCL-2 inhibition at antiretroviral therapy initiation reduces the intact SIV reservoir in macaques.
2026. szept. 3.· Nature microbiology· PUBMED