Liver cirrhosis: ki dolgozik rajta

Intézményenként egy kártya. Célpontra vagy országra szűkítheted a listát.

• Minden célpont
• PPAR 0
• GLP-1 0
• SGLT2 1
• mTOR 0
• AKT 0
• PI3K 0
• STAT3 0
• YAP 0
• AMPK 0
• TP53 0
• PNPLA3 1
• IL-17 0
• JAK 0
• MAPK 0
• NLRP3 0
• SIRT1 0
• TLR4 0
• STING 0
• CTNNB1 0
• HIF-1 0
• IL-6 0
• PD-1 0
• PD-L1 0
• CXCR4 0
• DPP-4 0
• JNK 0
• NRF2 0
• APOE 0
• BCL-2 0
• ERK 0
• EZH2 0
• FGFR 0
• HMGB1 0
• HSP90 0
• IL-23 0
• MDM2 0
• METTL3 0
• PCSK9 0
• PDGFR 0
• PSMA 1
• PTEN 0
• TNF 0
• VEGF 0
• ABL1 0
• ALK 0
• CD19 0
• CD20 0
• CD38 0
• COX-2 0
• FAK 0
• FTO 0
• IDH 0
• LAG-3 0
• MMP-9 0
• MYC 0
• NPM1 0
• PARP 0
• PKD1 0
• PKM2 0
• TERT 0

1+ intézményből 1, a friss publikációk és a nyitott vizsgálatok szerint rendezve. Ez nem minőségi rangsor.

Funded research projects that name this disease in their title, terms or summary and have not ended yet: who is funded, where, how much and until when. Organisations only; the funder's page has the details.

• European Commission (Horizon Europe) · HORIZON-TMA-MSCA-PF-GF

  Tracking the Intestinal Permeation and Circulation Effects of Environmental MicroPlastics (TRACE-MP)

  Queen Mary University of London· London, Egyesült Királyság· EU contribution 292 073 EUR· until 2029. jan.· 2 countries

  The disease is named only in the funder's project summary, not in the title.

• European Commission (Horizon Europe) · HORIZON-ERC-POC

  Epigenomic Liquid Biopsy for Early Detection and Monitoring of Metabolic Dysfunction-Associated Steatohepatitis (cfChIP-MASH)

  The Hebrew University of Jerusalem· Jerusalem, Izrael· EU contribution 150 000 EUR· until 2028. jan.

  The disease is named only in the funder's project summary, not in the title.

• European Commission (Horizon Europe) · HORIZON-ERC

  Scalable target identification for metabolic liver disease (3DMASH)

  Karolinska Institutet· Stockholm, Svédország· EU contribution 1 950 000 EUR· until 2030. jan.

  The disease is named only in the funder's project summary, not in the title.

• European Commission (Horizon Europe) · HORIZON-TMA-MSCA-PF-EF

  Promoting RObust Systems biology on Patients and Experimental models with obesity-driven liveR cancer (PROSPER)

  Medizinische Universitaet Wien· Wien, Ausztria· EU contribution 183 601 EUR· until 2026. dec.

  The disease is named only in the funder's project summary, not in the title.

• European Commission (Horizon Europe) · HORIZON-ERC

  Function of Cholangiocytes in chronic liver diseases (FunChol)

  Charite - Universitaetsmedizin Berlin· Berlin, Németország· EU contribution 2 499 289 EUR· until 2029. dec.

  The disease is named only in the funder's project summary, not in the title.

5 of 10 running projects, newest first. Listed amounts together: 43,8 M EUR.

Sources: NIH RePORTER (U.S. National Institutes of Health, public domain) and CORDIS (European Commission, CC BY 4.0). Changes: filtered by disease, organisations matched to ROR.

Vizsgálatok, amelyek regiszteradata szerint az egyéni résztvevői adatokat (IPD) megosztják.

• A Study to Evaluate AZD2693 in Participants Who Are Carriers of the PNPLA3 148M Risk Allele With Non-cirrhotic Non-alcoholic Steatohepatitis With Fibrosis

  NCT05809934· AstraZeneca· Forrás

Publikációk erről a betegségről egy MeSH-módszerkifejezés szerint, például szekvenálási vagy képalkotó módszerre.

• Single-Cell Analysis 17
• Organoids 16
• Mendelian Randomization Analysis 26
• CRISPR-Cas Systems 3
• Gene Expression Profiling 77
• Sequence Analysis, RNA 2
• Whole Genome Sequencing 1
• Exome Sequencing 2
• Proteomics 58
• Metabolomics 53
• Mass Spectrometry 9
• Flow Cytometry 9
• Immunohistochemistry 36
• Liquid Biopsy 7
• Circulating Tumor DNA 3
• Xenograft Model Antitumor Assays 4
• Positron-Emission Tomography 9
• Magnetic Resonance Imaging 131
• Machine Learning 88
• Deep Learning 30
• Cohort Studies 178
• Genome-Wide Association Study 34

• Mechanistic insights and translational perspectives on liver fibrosis through single-cell transcriptomics.

  Front Immunol, 2026. okt.

• Integrated single-cell and epigenomic analysis reveals cellular specificity of CYP2E1 in human alcohol-related liver disease.

  Toxicol Sci, 2026. okt.

• Pan-Fibrotic Gene Expression Signature in Major Chronic Diseases by Integrative Bulk and Single-Cell Transcriptomic Analyses.

  Int J Mol Sci, 2026. szept.

• A human single-cell atlas identifies OLR1+ scar-associated macrophages as a potential therapeutic target for chronic liver disease.

  Nat Genet, 2026. szept.

• Machine Learning-Assisted SERS Quantification of Sialylated Alpha-Fetoprotein: From Single-Cell Analysis to Hepatocellular Carcinoma Risk Assessment.

  Small Methods, 2026. júl.

• Single-cell and spatial transcriptomics reveal Thbs1-CD36 crosstalk between Kupffer and hepatic stellate cells following mesenchymal stem cell-derived small extracellular vesicles transplantation, alleviating liver fibrosis.

  J Nanobiotechnology, 2026. máj.

• Integrated Bulk and Single-Cell Transcriptomic Analysis Reveals Xenobiotic Metabolism Genes Drive Progression From Liver Cirrhosis to Hepatocellular Carcinoma.

  Hum Mutat, 2026. máj.

• Single-cell profiling of T/NK cell glycosylation and interaction networks during liver cirrhosis.

  Dig Liver Dis, 2026. ápr.

• Integrated Single-Cell Mass Spectrometry Imaging and Immunofluorescence Microscopy for Multimodal Characterization of Human Immune Cells.

  Anal Chem, 2026. ápr.

• Conserved Ductular Reaction Mechanisms in Biliary Atresia and Primary Sclerosing Cholangitis Derived From Single-Cell and Spatial Transcriptomics.

  Cell Mol Gastroenterol Hepatol, 2026. márc.

Megmutatjuk, a betegség mely célpontjait említi az absztrakt, és onnan a rajtuk dolgozókhoz jutsz.