Krónikus mieloid leukémia (CML): ki dolgozik rajta

Intézményenként egy kártya. Célpontra vagy országra szűkítheted a listát.

• Minden célpont
• ABL1 12
• TP53 1
• JAK 1
• AKT 0
• IDH 4
• ERK 0
• FLT3 2
• PI3K 0
• JNK 0
• STAT3 0
• BCL-2 2
• CD19 1
• HSP90 0
• KIT 1
• PDGFR 0
• CSF1R 2
• HDAC 0
• HIF-1 0
• IL-1 2
• MAPK 0
• PPAR 0
• AMPK 0
• CD123 0
• CD38 1
• CTNNB1 0
• EGFR 0
• FGFR 0
• mTOR 0
• NLRP3 0
• NRF2 0
• RAS 0
• RUNX1 0
• BTK 0
• CD20 0
• CD22 0
• CD33 0
• CD40 0
• CD47 1
• CTLA-4 0
• CXCR4 0
• G6PD 0
• GLP-1 0
• IL-15 0
• IL-6 1
• KRAS 0
• MEK 1
• MYC 0
• NPM1 0
• NRAS 0
• PD-1 0
• PRMT5 0
• PTEN 0
• SGLT2 0
• SIRT1 0
• TIM-3 0
• YAP 0

4+ intézményből 4, a friss publikációk és a nyitott vizsgálatok szerint rendezve. Ez nem minőségi rangsor.

Funded research projects that name this disease in their title, terms or summary and have not ended yet: who is funded, where, how much and until when. Organisations only; the funder's page has the details.

• NIH NCI · R01

  The Role of Cell Competition in Shaping the Clonal Structure of Hematopoiesis

  Washington University· Saint Louis, Egyesült Államok· 465 749 USD awarded in fiscal year 2026· until 2031. aug.

• NIH NCI · K99

  The Epitranscriptomic-Microtubule Axis as a Novel Mechanism of Ponatinib induced Cardiotoxicity

  University of Illinois at Chicago· Chicago, Egyesült Államok· 139 113 USD awarded in fiscal year 2026· until 2028. aug.

• NIH NCI · R21

  Interferon-γ in combination with donor leukocyte infusion to treat relapsed acute myeloid leukemia and myelodysplastic syndromes after haploidentical donor stem cell transplantation

  University of Pittsburgh at Pittsburgh· Pittsburgh, Egyesült Államok· 408 829 USD awarded in fiscal year 2026· until 2028. aug.

• NIH NCI · F31

  Role of ABL kinases in regulating DNA damage repair and transcription-replication conflicts in SCLC tumors

  Duke University· Durham, Egyesült Államok· 43 742 USD awarded in fiscal year 2026· until 2029. aug.

• NIH NCI · F30

  From Resistance to Innovation: Towards Countering Asciminib Resistance and Designing Next-Generation Allosteric Inhibitors against CML

  State University New York Stony Brook· Stony Brook, Egyesült Államok· 42 647 USD awarded in fiscal year 2026· until 2030. aug.

• European Commission (Horizon 2020) · ERC-STG

  Functional Interrogation of Non-coding DNA Sequences in leukemia development and drug resistance (FIND-seq)

  St. Anna Kinderkrebsforschung Gmbh· Wien, Ausztria· EU contribution 1 784 000 EUR· until 2027. aug.

  The disease is named only in the funder's project summary, not in the title.

6 of 51 running projects, newest first. Listed amounts together: 33,5 M USD + 1,8 M EUR.

Sources: NIH RePORTER (U.S. National Institutes of Health, public domain) and CORDIS (European Commission, CC BY 4.0). Changes: filtered by disease, organisations matched to ROR.

Vizsgálatok, amelyek regiszteradata szerint az egyéni résztvevői adatokat (IPD) megosztják.

Ebben a nézetben egy vizsgálat sem jelzi, hogy megosztaná a résztvevői adatokat.

Publikációk erről a betegségről egy MeSH-módszerkifejezés szerint, például szekvenálási vagy képalkotó módszerre.

• Single-Cell Analysis 4
• Mendelian Randomization Analysis 3
• CRISPR-Cas Systems 2
• Gene Expression Profiling 6
• Sequence Analysis, RNA 2
• Exome Sequencing 1
• Proteomics 5
• Metabolomics 3
• Mass Spectrometry 2
• Flow Cytometry 13
• Xenograft Model Antitumor Assays 19
• Magnetic Resonance Imaging 4
• Machine Learning 3
• Cohort Studies 9
• Genome-Wide Association Study 3

• Extramedullary T-Lymphoblastic Blast Crisis in Chronic Myeloid Leukaemia: A Unique Cytologic Diagnosis Confirmed by Flow Cytometry.

  Cytopathology, 2026. szept.

• Peripheral Blood Profiles Reflecting Progenitor Lineage Balance are Associated With Molecular Response in Chronic Myeloid Leukemia.

  Exp Hematol, 2026. aug.

• What is the optimal threshold for aberrant lymphoblasts at diagnosis to predict lymphoid transformation in chronic myeloid leukemia?

  Cytometry B Clin Cytom, 2026. jún.

• Simultaneous chromatographic quantification of upadacitinib, nilotinib, and tryptophan decoding myeloid leukemia and liver cancer integrated with ELISA and Flow cytometry.

  J Chromatogr B Analyt Technol Biomed Life Sci, 2025. dec.

• Chemopreventive Effects of Dietary Eicosapentaenoic Acid Supplementation in Experimental Myeloid Leukemia.

  Cancer Prev Res (Phila), 2015. aug.

• Coformulation of doxorubicin and curcumin in poly(D,L-lactide-co-glycolide) nanoparticles suppresses the development of multidrug resistance in K562 cells.

  Mol Pharm, 2011. ápr.

• Curcumin stimulates reactive oxygen species production and potentiates apoptosis induction by the antitumor drugs arsenic trioxide and lonidamine in human myeloid leukemia cell lines.

  J Pharmacol Exp Ther, 2010. júl.

• [Reactive oxygen species and mitochondrial membrane potential changes in leukemia cells during 6-gingerol induced apoptosis].

  Zhong Yao Cai, 2010. ápr.

• Combination of simvastatin and imatinib sensitizes the CD34+ cells in K562 to cell death.

  Med Oncol, 2010. márc.

• [Effect of berberine on the differentiation and apoptosis of K562 cell line].

  Zhong Yao Cai, 2009. márc.

Megmutatjuk, a betegség mely célpontjait említi az absztrakt, és onnan a rajtuk dolgozókhoz jutsz.