Osteoarthritis: ki dolgozik rajta

Intézményenként egy kártya. Célpontra vagy országra szűkítheted a listát.

• Minden célpont
• GLP-1 2
• MAPK 0
• PI3K 0
• AKT 0
• IL-6 0
• mTOR 0
• NLRP3 0
• STAT3 0
• AMPK 0
• JAK 0
• NRF2 0
• COX-2 0
• SIRT1 0
• STING 0
• TNF 0
• VEGF 0
• CGRP 0
• ERK 0
• FTO 0
• HIF-1 0
• IL-1 0
• RANKL 0
• SGLT2 0
• TP53 0
• APP 0
• CDK4/6 0
• CFTR 0
• CTNNB1 0
• EGFR 0
• GIP 0
• HER2 0
• IL-15 0
• JNK 0
• METTL3 0
• MMP-9 0
• PINK1 0
• PPAR 0
• TLR4 0
• YAP 0

Funded research projects that name this disease in their title, terms or summary and have not ended yet: who is funded, where, how much and until when. Organisations only; the funder's page has the details.

• European Commission (Horizon Europe) · HORIZON-ERC

  Biofabrication of gene activated grafts targeting synovial joint inflammation and meniscus repair (SMART-MENISCUS)

  The Provost, Fellows, Foundation Scholars & the Other Members of Board, of the College of the Holy & Undivided Trinity of Queen Elizabeth Near Dublin· Dublin, Írország· EU contribution 1 500 000 EUR· until 2032. jan.

  The disease is named only in the funder's project summary, not in the title.

• European Commission (Horizon Europe) · HORIZON-RIA

  EV-enriched secretome from cord blood as a new disease modifying treatment for osteoarthritis (ExoCordOA)

  Exogenus Therapeutics Sa· Cantanhede, Portugália· EU contribution 13 000 000 EUR· until 2031. aug.· 3 countries

• European Commission (Horizon Europe) · HORIZON-TMA-MSCA-PF-EF

  Smart Platforms for Osteochondral Regeneration through on-demand Activation (SPORA)

  Instituto Superior Tecnico· Lisboa, Portugália· EU contribution 191 343 EUR· until 2028. aug.

• European Commission (Horizon Europe) · HORIZON-TMA-MSCA-PF-EF

  Newly engineered lignin nanocarrier for curcumin delivery to tackle inflammation and limited synovial drug residence in osteoarthritis (LigNPsCURCDeLIV)

  University of Leeds· Leeds, Egyesült Királyság· EU contribution 276 188 EUR· until 2028. szept.

• European Commission (Horizon Europe) · HORIZON-TMA-MSCA-PF-EF

  Gene-activated tri-layer 3D-bioprinted scaffold for enhanced osteochondral defect repair (GATSO-3D)

  Royal College of Surgeons in Ireland· Dublin 2, Írország· EU contribution 252 729 EUR· until 2028. júl.

  The disease is named only in the funder's project summary, not in the title.

5 of 25 running projects, newest first. Listed amounts together: 106,0 M EUR.

Sources: NIH RePORTER (U.S. National Institutes of Health, public domain) and CORDIS (European Commission, CC BY 4.0). Changes: filtered by disease, organisations matched to ROR.

Vizsgálatok, amelyek regiszteradata szerint az egyéni résztvevői adatokat (IPD) megosztják.

• A Study to Learn About Study Medicine Called Berobenatide in Adults With Knee Pain and Overweight or Obesity (VESPER-OA 1)

  NCT07919678· Pfizer· Forrás

• A Study to Learn About Berobenatide Given Once Weekly in Adults With Knee Osteoarthritis and Overweight or Obesity With or Without Type 2 Diabetes (VESPER-OA 2)

  NCT07915609· Pfizer· Forrás

Publikációk erről a betegségről egy MeSH-módszerkifejezés szerint, például szekvenálási vagy képalkotó módszerre.

• Single-Cell Analysis 43
• Organoids 4
• Mendelian Randomization Analysis 55
• CRISPR-Cas Systems 1
• Gene Expression Profiling 106
• Sequence Analysis, RNA 11
• Whole Genome Sequencing 3
• Exome Sequencing 1
• Proteomics 43
• Metabolomics 26
• Mass Spectrometry 5
• Flow Cytometry 7
• Immunohistochemistry 19
• Positron-Emission Tomography 6
• Magnetic Resonance Imaging 276
• Machine Learning 78
• Deep Learning 45
• Cohort Studies 148
• Genome-Wide Association Study 48

• Integrative Genetic, Transcriptomic, and Single-Cell Analyses Prioritize Druggable Candidate Genes in Knee Osteoarthritis.

  FASEB J, 2026. okt.

• Oxidative stress-driven cellular heterogeneity in Knee Osteoarthritis: scRNA-seq pinpoints SPP1 and CYBA for diagnostic development.

  PLoS One, 2026. okt.

• Spatial multiomics identifies rheumatoid arthritis synovial niches and de-novo laminar histological patterns of fibroblasts subtypes.

  Front Immunol, 2026. okt.

• Single-cell transcriptomics and machine learning characterize LTA4H-linked lipid metabolism and inflammatory signatures in the knee osteoarthritis IPFP/synovium compartment.

  PLoS One, 2026. okt.

• Single-Cell Analysis of Cartilage-Derived Cells Identifies Diverse Populations and a Cholesterol/ER-Stress Chondrocyte Subset in Knee OA.

  J Orthop Res, 2026. okt.

• Proteome-wide Mendelian randomization and transcriptome analysis of a novel osteoarthritis blood-targeting USP8, single-cell model and experimental validation.

  Int Immunopharmacol, 2026. szept.

• Single-cell and spatial transcriptomics analysis of osteoarthritis: pathway regulation, cell interaction networks, and therapeutic translation.

  J Transl Med, 2026. aug.

• Single-cell expression quantitative trait loci-based Mendelian randomization identifies MAN1A2 in naive CD4+ T cells as a candidate therapeutic target for osteoarthritis.

  Exp Gerontol, 2026. júl.

• Integrated bulk and single-cell transcriptomic analyses and experimental validation reveal the pathogenic role of chondrocyte pyroptosis in osteoarthritis and the therapeutic potential of curcumin via its targeted modulation.

  Naunyn Schmiedebergs Arch Pharmacol, 2026. júl.

• Bisphenol A drives the comorbidity of non-alcoholic fatty liver disease and osteoarthritis by targeting RHOB: Integrated multi-omics, single-cell analysis, and experimental validation.

  Exp Gerontol, 2026. júl.

Megmutatjuk, a betegség mely célpontjait említi az absztrakt, és onnan a rajtuk dolgozókhoz jutsz.