Thalassaemia: trials for referral
91 open trials in the registries we read. Each row links to its registry record.
Registry data only. Frontlight does not judge whether a patient can take part: the trial team decides.
Where the open trials are
Type a city to sort by distance. The distance is worked out in your browser; the city is not sent anywhere.
91 trials shown
No phase1 site
Not yet recruitingChina
NCT03351829
Gene Therapy of Beta Thalassemia Using a Self-inactivating Lentiviral Vector
Shenzhen Geno-Immune Medical Institute
Registry updated 2 Nov 2026
Registry record: ClinicalTrials.govPhase 1/22 sites
RecruitingChina
NCT06280378
β-Thalassemia Treatment With KL003 Cell Injection
Kanglin Biotechnology (Hangzhou) Co., Ltd.
Registry updated 2 Nov 2026
Registry record: ClinicalTrials.govPhase 38 sites
RecruitingGreece, Italy, United States
NCT07506863
A Study to Investigate the Efficacy, Pharmacokinetics, and Safety of Mitapivat in Pediatric Participants With Transfusion-Dependent Alpha- or Beta-Thalassemia (α- or β-TDT)
Agios Pharmaceuticals, Inc.
Registry updated 29 Oct 2026
Registry record: ClinicalTrials.govPhase 423 sites
By invitation onlyBelgium, Brazil, Canada, France, United Kingdom, Israel
NCT05777993
A Study to Provide Access to Mitapivat for Participants Who Previously Participated in an Agios-Sponsored Mitapivat Study
Agios Pharmaceuticals, Inc.
Registry updated 28 Oct 2026
Registry record: ClinicalTrials.govPhase 37 sites
RecruitingGreece, Italy, United States
NCT07517133
A Study to Investigate the Efficacy, Pharmacokinetics, and Safety of Mitapivat in Pediatric Participants With α- or β-Non-Transfusion-Dependent Thalassemia
Agios Pharmaceuticals, Inc.
Registry updated 28 Oct 2026
Registry record: ClinicalTrials.govNo phase1 site
RecruitingChina
NCT06479616
A Long-term Follow-up Study in Participants Who Received CS-101
Children's Hospital of Fudan University
Registry updated 26 Oct 2026
Registry record: ClinicalTrials.govPhase 1/21 site
RecruitingUnited States
NCT04008368
Repeat Peripheral Blood Stem Cell Transplantation for Patients With Sickle Cell Disease and Falling Donor Myeloid Chimerism Levels
National Heart, Lung, and Blood Institute (NHLBI)
Registry updated 26 Oct 2026
Registry record: ClinicalTrials.govPhase 21 site
RecruitingUnited States
NCT04099966
AlloSCT for Malignant and Non-malignant Hematologic Diseases Utilizing Alpha/Beta T Cell and CD19+ B Cell Depletion
Mitchell Cairo
Registry updated 23 Oct 2026
Registry record: ClinicalTrials.govPhase 31 site
RecruitingPakistan
NCT07884773
Combination Therapy With Danazol, Prednisolone, and Thalidomide for Thalidomide-Refractory Transfusion-Dependent β-Thalassemia
Khyber Medical University Peshawar
Registry updated 21 Oct 2026
Registry record: ClinicalTrials.govNo phase0 sites
Not yet recruiting
NCT07882303
Native T1 Mapping and ECV in Chronic Hemolytic Anemia
Assiut University
Registry updated 20 Oct 2026
Registry record: ClinicalTrials.govPhase 1/21 site
RecruitingUnited States
NCT07599176
Partial Stem Cell Transplant for Sickle Cell Disease From Matched Donors
National Heart, Lung, and Blood Institute (NHLBI)
Registry updated 13 Oct 2026
Registry record: ClinicalTrials.govNo phase1 site
RecruitingFrance
NCT07207577
Evaluation of Physiological and Psychological Factors Involved in Exercise Intolerance in Patients With β-TTD
Centre Hospitalier Metropole Savoie
Registry updated 7 Oct 2026
Registry record: ClinicalTrials.govNo phase0 sites
Not yet recruiting
NCT07614217
Oral Health Status in Children With β-Thalassemia Major
Cairo University
Registry updated 7 Oct 2026
Registry record: ClinicalTrials.govNo phase1 site
RecruitingUnited States
NCT03937817
Collection of Human Biospecimens for Basic and Clinical Research Into Globin Variants
National Institute of Allergy and Infectious Diseases (NIAID)
Registry updated 2 Oct 2026
Registry record: ClinicalTrials.govEarly Phase 11 site
RecruitingUnited States
NCT06313398
Determination of Red Cell Survival in Sickle Cell Disease and Other Hemoglobinopathies Using Biotin Labeling
National Heart, Lung, and Blood Institute (NHLBI)
Registry updated 28 Sept 2026
Registry record: ClinicalTrials.govPhase 3101 sites
RecruitingCanada, Germany, Egypt, Spain, France, United Kingdom
NCT06609226
A Research Study Looking at Long-term Treatment With Etavopivat in People With Sickle Cell Disease or Thalassaemia
Novo Nordisk A/S
Registry updated 18 Sept 2026 · The registries disagree on the status
Registry record: ClinicalTrials.govNo phase1 site
RecruitingUnited States
NCT04872179
International Registry of Patients With Alpha Thalassemia
University of California, San Francisco
Registry updated 2 Sept 2026
Registry record: ClinicalTrials.govNo phase0 sites
Not yet recruiting
NCT07796022
Clinical, Economic,and Psychosocial Burden of Thalassemia in Sohag
Randa Elham Hamam
Registry updated 31 Aug 2026
Registry record: ClinicalTrials.govNo phase13 sites
RecruitingUnited Arab Emirates, Kuwait, Oman, Saudi Arabia
NCT07215975
A Real-World Study to Evaluate Luspatercept in Adults With Transfusion-Dependent Beta-Thalassemia in the Middle East
Bristol-Myers Squibb
Registry updated 19 Aug 2026
Registry record: ClinicalTrials.govNo phase0 sites
Not yet recruiting
NCT07774351
A Clinical Exploratory Study of YOLT-204 in the Treatment of Hemoglobinopathies
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Registry updated 19 Aug 2026
Registry record: ClinicalTrials.govNo phase76 sites
RecruitingUnited States
NCT04398628
ATHN Transcends: A Natural History Study of Non-Neoplastic Hematologic Disorders
American Thrombosis and Hemostasis Network
Registry updated 17 Aug 2026
Registry record: ClinicalTrials.govPhase 1/21 site
RecruitingUnited States
NCT03653338
T-Cell Depleted Alternative Donor Bone Marrow Transplant for Sickle Cell Disease (SCD) and Other Anemias
Paul Szabolcs
Registry updated 13 Aug 2026
Registry record: ClinicalTrials.govPhase 320 sites
By invitation onlyBelgium, Canada, Germany, United Kingdom, Italy, United States
NCT04208529
A Long-term Follow-up Study in Participants Who Received CTX001
Vertex Pharmaceuticals Incorporated
Registry updated 11 Aug 2026
Registry record: ClinicalTrials.govNo phase1 site
RecruitingPakistan
NCT07673302
Safety and Efficacy of Hemoglobin F Inducers in Patients With Beta Thalassemia
Riphah International University
Registry updated 6 Aug 2026
Registry record: ClinicalTrials.govPhase 24 sites
RecruitingUnited States
NCT02675959
Myeloablative Conditioning, Prophylactic Defibrotide and Haplo AlloSCT for Patients With Sickle Cell Disease
New York Medical College
Registry updated 27 Jul 2026
Registry record: ClinicalTrials.govPhase 22 sites
RecruitingItaly
NCT07680803
Gene-Modified Stem Cell Therapy for Subjects With Transfusion-dependent Beta-thalassemia
Fondazione Telethon
Registry updated 27 Jul 2026
Registry record: ClinicalTrials.govNo phase1 site
RecruitingChina
NCT07725263
Low-Dose Liposomal Amphotericin B for Invasive Fungal Infection Prophylaxis in Neutropenic Children
Haikou Affiliated Hospital of Central South University Xiangya School of Medicine
Registry updated 24 Jul 2026
Registry record: ClinicalTrials.govPhase 20 sites
Not yet recruiting
NCT07721480
Gene Therapy for Patients With Transfusion-Dependent β-Thalassemia
Prince of Wales Hospital, Shatin, Hong Kong
Registry updated 23 Jul 2026
Registry record: ClinicalTrials.govNo phase7 sites
RecruitingChina
NCT06298630
Long-term Follow-up Study of BRL-101 for TDT
Bioray Laboratories
Registry updated 21 Jul 2026
Registry record: ClinicalTrials.govPhase 20 sites
Not yet recruiting
NCT07698080
Dexamethasone, Intravenous Injection of Human Immunoglobulin, and Increased Infusion of Mononuclear Cells to Reduce Donor Specific Antibodies in Haploidentical Hematopoietic Stem Cell Transplantation
Hematology department of the 920th hospital
Registry updated 14 Jul 2026
Registry record: ClinicalTrials.gov
The same sites as a list
- China29 open trials
- United States28 open trials
- Italy11 open trials
- Greece8 open trials
- Canada7 open trials
- Spain6 open trials
- Belgium5 open trials
- Germany5 open trials
- United Kingdom4 open trials
- France4 open trials
- Pakistan4 open trials
- Israel3 open trials
- Egypt3 open trials
- Saudi Arabia3 open trials
- Japan2 open trials
- Nigeria2 open trials
- Oman2 open trials
- Lebanon2 open trials
- India2 open trials
- Thailand2 open trials
- Malaysia2 open trials
- Denmark2 open trials
- Brazil1 open trials
- Kenya1 open trials
- Ghana1 open trials
- Kuwait1 open trials
- United Arab Emirates1 open trials
- Australia1 open trials
- Bulgaria1 open trials
- Sweden1 open trials
- Taiwan1 open trials
- Poland1 open trials
- South Korea1 open trials
- Austria1 open trials
- Angola1 open trials
- Cyprus1 open trials
- Brunei1 open trials
- Argentina1 open trials
- Portugal1 open trials
Who treats this
Institutions with trials or publications in this disease (OpenAlex, registries). Institutions only, no people.
Chinese Academy of Medical Sciences & Peking Union Medical College
Beijing, China
1 trials · 25 publications · ROR
Cincinnati Children's Hospital Medical Center
Cincinnati, United States
1 trials · 20 publications · ROR
First Affiliated Hospital of GuangXi Medical University
Nanning, China
0 trials · 85 publications · ROR
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
Milan, Italy
3 trials · 47 publications · ROR
Fourth Affiliated Hospital of Guangxi Medical University
Liuzhou, China
2 trials · 15 publications · ROR
High Institute for Education and Research in Transfusion Medicine
Tehran, Iran
0 trials · 13 publications · ROR
Khalifa University of Science and Technology
Abu Dhabi, United Arab Emirates
0 trials · 26 publications · ROR
Post Graduate Institute of Medical Education and Research
Chandigarh, India
0 trials · 29 publications · ROR
The People's Hospital of Guangxi Zhuang Autonomous Region
Nanning, China
0 trials · 20 publications · ROR
The University of Texas MD Anderson Cancer Center
Houston, United States
1 trials · 13 publications · ROR
University of North Carolina at Chapel Hill
Chapel Hill, United States
0 trials · 21 publications · ROR
What changed in the last 7 days
Registry facts, one per line, newest first.
Phase changed: No phase → Phase 3
NCT02633943 · Phase 3 · Australia, Germany, France, United Kingdom, Greece, Italy
Source: ClinicalTrials.gov
Results card
Trials that finished or stopped in the last 3 years, with the reason the registry gives and linked publications.
Phase 2Ended 1 Aug 2026
Completed100 participants
NCT07863791
Effect of Omega 3 Fatty Acids on Heart and Liver in Beta Thalassemia Patients
No phaseEnded 30 Apr 2026
Completed30 participants
NCT07003269
Observational Study: Hetrombopag for Platelet Recovery in Haploidentical HSCT
No phaseEnded 30 Apr 2026
Completed16 participants
NCT07003256
Observational Study: Romiplostim for Platelet Recovery in Haploidentical HSCT
Phase 4Ended 9 Feb 2026
Completed96 participants
NCT06606886
Effects of Hydroxyurea and Metformin in Transfusion Dependent Beta-Thalassemia
Phase 4Ended 30 Jan 2026
Phase 2Ended 5 Jan 2026
Completed80 participants
NCT07370922
Glucagon-Like Peptide 1 Receptor Agonist in Diabetes Mellitus Management in Children and Adolescents With Transfusion-Dependent Thalassemia
No phaseEnded 31 Dec 2025
Completed55 participants
NCT04171635
Quantitative Susceptibility Mapping (QSM) to Guide Iron Chelating Therapy
Phase 2Ended 30 Dec 2025
Completed100 participants
NCT07292259
Combination of Thalidomide and Hydroxyuria in Transfusion Dependent Thalasemmia
Phase 1Ended 17 Nov 2025
Completed9 participants
NCT06291961
A Safety and Efficacy Study Evaluating CS-101 in Subjects With β-Thalassemia Major
Phase 2/3Ended 13 Nov 2025
Completed59 participants
NCT03655678
A Safety and Efficacy Study Evaluating CTX001 in Participants With Transfusion-Dependent β-Thalassemia
No phaseEnded 1 Oct 2025
No phaseEnded 30 Sept 2025
Completed8400 participants
NCT07305181
Prevalence of Abnormal Haemoglobin Variants in Metropolitan Chattogram, Bangladesh
Phase 2/3Ended 27 Sept 2025
Completed8 participants
NCT07210450
Effect of L-Glutamine on Pulmonary Artery Pressure in Patients With Non-Transfusion-Dependent Thalassemia
Phase 2Ended 24 Sept 2025
Completed53 participants
NCT04987489
A Study of Etavopivat in Patients With Thalassemia or Sickle Cell Disease
Phase 1Ended 22 Sept 2025
Completed33 participants
NCT07023029
A Study on the Effect of Etavopivat on Heart Rhythm in Healthy Participants
No phaseEnded 16 Sept 2025
Completed36 participants
NCT04688411
An mHealth Strategy to Improve Medication Adherence in Adolescents With Sickle Cell Disease
No phaseEnded 4 Sept 2025
Completed760 participants
NCT07207551
Prevalence of Hemoglobinopathies Associated With Significant Hb Variants in the Chattogram Region of Bangladesh
Early Phase 1Ended 12 Aug 2025
Completed2 participants
NCT06065189
Base-edited Autologous Hematopoietic Stem Cell Transplantation in Treating Patients With β-thalassemia Major
No phaseEnded 31 Jul 2025
Completed10 participants
NCT01758042
Bone Marrow and Kidney Transplant for Patients With Chronic Kidney Disease and Blood Disorders
Early Phase 1Ended 1 Jul 2025
Completed5 participants
NCT06024876
A Clinical Study Evaluating the Safety and Efficacy of CS-101 in Treating Subjects With β-thalassemia
No phaseEnded 2 Jun 2025
No phaseEnded 2 Jun 2025
Completed100 participants
NCT07153926
Elastography vs Iron Regulators in the Diagnosis of Hepatic Fibrosis- Iron Overload in Children With Beta- Thalassemia
No phaseEnded 29 May 2025
Completed68 participants
NCT04691323
The Longitudinal Relationship of HU Adherence to HRQOL, Barriers to Adherence and Habit in SCD.
Phase 1Ended 27 May 2025
Completed37 participants
NCT06813924
A Research Study of the Effect of Etavopivat on Other Drugs in Healthy Participants
Phase 2Ended 6 Mar 2025
Completed16 participants
NCT05355766
Long-term Clinical Study of CN128 in Thalassemia With Sever Liver Iron Overloaded Patients
No phaseEnded 31 Dec 2024
Completed2 participants
NCT05015920
A Study Evaluating the Safety and Efficacy of the BD211 Drug Product in β-Thalassemia Major Participants
No phaseEnded 31 Dec 2024
Completed121 participants
NCT06888232
Safety and Efficacy of Immunomodulator Drug Thalidomide in Multi-transfused Thalassemia Patients
No phaseEnded 28 Dec 2024
Phase 1Ended 31 Oct 2024
Completed24 participants
NCT06581627
A Research Study Looking at a Single Dose of Etavopivat in Healthy Chinese Participants
Phase 1Ended 31 Oct 2024
No phaseEnded 20 Aug 2024
Completed115 participants
NCT07099196
Impact of Virtual Reality on Pain and Anxiety During Intravenous Cannulation Procedures Among Thalassemia Patients in UAE.
Phase 1Ended 8 Jul 2024
Completed16 participants
NCT06433661
A Research Study of the Effect of Food on Etavopivat in Healthy Participants
No phaseEnded 14 May 2024
Completed75 participants
NCT06889727
Pregnancy and Childbirth in Women with Thalassemia Yesterday and Today
No phaseEnded 30 Apr 2024
No phaseEnded 31 Mar 2024
Completed157 participants
NCT05255445
Red Blood Cell - IMProving trAnsfusions for Chronically Transfused Recipients
Phase 1Ended 28 Feb 2024
Completed60 participants
NCT06098014
Safety & Efficacy of Thalidomide in Children With Transfusion Dependent Thalassemia
No phaseEnded 28 Feb 2024
Completed199 participants
NCT06210139
Pharmacotherapy Prescribing Pattern and the Adherence Level to Iron Chelation Therapy in Thalassemia
No phaseEnded 31 Dec 2023
Completed684 participants
NCT06831799
ERN-EuroBloodNet Registry on Patients With Rare Red Blood Cell Defects and COVID-19
No phaseEnded 27 Nov 2023
Completed6 participants
NCT04211480
Safety and Efficacy Evaluation of γ-globin Reactivated Autologous Hematopoietic Stem Cells
Not medical advice. fetched 4 Nov 2026