Sarcoma: who works on it

One card per institution. Pick a target or a country to narrow the list.

• All targets
• KRAS 10
• TP53 1
• PD-1 19
• PD-L1 9
• PI3K 0
• AKT 0
• NTRK 2
• mTOR 0
• STAT3 0
• MAPK 0
• CTNNB1 0
• MDM2 2
• BRAF 3
• MYC 0
• RAS 3
• ERK 0
• JNK 0
• VEGF 3
• ALK 2
• B7-H3 10
• STING 1
• CDK4/6 3
• EGFR 1
• JAK 1
• PARP 4
• YAP 0
• IDH 2
• FGFR 2
• HER2 5
• MEK 2
• CTLA-4 5
• NRAS 0
• GPX4 0
• HIF-1 0
• PTEN 0
• EZH2 0
• PPAR 0
• METTL3 1
• NF1 5
• AMPK 0
• GPC3 5
• PDGFR 3
• ABL1 0
• CD47 0
• COX-2 0
• ROS1 2
• AXL 0
• CDKN2A 0
• CXCR4 0
• IL-15 4
• MMP-9 0
• PRAME 1
• PSMA 0
• RET 0
• BCL-2 0
• BRCA2 1
• CD19 2
• FLT3 0
• FTO 0
• HDAC 0

24 of 30+ institutions, ordered by recent publications and open trials. This is not a ranking of quality.

Funded research projects that name this disease in their title, terms or summary and have not ended yet: who is funded, where, how much and until when. Organisations only; the funder's page has the details.

• FDA · U01

  Disulfiram/Copper as a Dual Senolytic Strategy Targeting Tumor and Immune Cell Senescence in Chordoma

  Massachusetts General Hospital· Boston, United States· US$1,000,000 awarded in fiscal year 2026· until Aug 2028

• NIH NIA · R01

  Synapse repair in Alzheimer's disease and related dementias

  Buck Institute for Research on Aging· Novato, United States· US$785,081 awarded in fiscal year 2026· until Jul 2031

• NIH NINDS · R43

  Development of an Anti-Nerve Growth Factor Active Immunotherapy for Difficult-to-Manage Pain

  Twilight Bioscience, Inc.· Topsfield, United States· US$350,188 awarded in fiscal year 2026· until Aug 2028

• NIH NIAMS · R21

  Failure to resolve an adaptive stress state contributes to Duchenne Muscular Dystrophy Severity

  University of Southern California· Los Angeles, United States· US$211,650 awarded in fiscal year 2026· until Aug 2028

• NIH NCI · R43

  Preclinical development of novel dual EZH2-BRD4 inhibitor for EZH2-mutant lymphoma

  Biologica Llc· Charlotte, United States· US$385,056 awarded in fiscal year 2026· until Aug 2027

• European Commission (Horizon Europe) · HORIZON-ERC

  Primary bone cancer scaffolds as controlled release non-viral gene delivery platforms (PANACEA)

  Royal College of Surgeons in Ireland· Dublin 2, Ireland· EU contribution €2,302,626· until May 2031

• European Commission (Horizon Europe) · HORIZON-TMA-MSCA-PF-EF

  Self-Assembling, Self-Monitoring, Multi-Stimuli-Responsive Implants for the Minimally Invasive Treatment of Critical-Size Defects (Morphogenesis)

  Fundacion Imdea Materiales· Getafe, Spain· EU contribution €194,075· until Mar 2028

  The disease is named only in the funder's project summary, not in the title.

• European Commission (Horizon Europe) · HORIZON-TMA-MSCA-PF-EF

  Investigating the role of RNA-binding proteins in telomere replication stress and alternative lengthening of telomeres (RBPandALT)

  The Francis Crick Institute Limited· London, United Kingdom· EU contribution €260,348· until Mar 2028

  The disease is named only in the funder's project summary, not in the title.

• European Commission (Horizon Europe) · HORIZON-TMA-MSCA-PF-EF

  Predicting single-cell ploidy from digital pathology images in pan-sarcoma (SImPloidy)

  University College London· London, United Kingdom· EU contribution €276,188· until May 2027

  The disease is named only in the funder's project summary, not in the title.

• European Commission (Horizon Europe) · HORIZON-IA

  Sustainable 4D hydrogels functionalised with plant-based nanoparticles for bone regeneration in cancer patients (GreenNanoBone)

  The University of Liverpool· Liverpool, United Kingdom· EU contribution €8,649,982· until May 2029· 12 countries

  The disease is named only in the funder's project summary, not in the title.

10 of 473 running projects, newest first. Listed amounts together: US$249.7m + €53.4m.

Sources: NIH RePORTER (U.S. National Institutes of Health, public domain) and CORDIS (European Commission, CC BY 4.0). Changes: filtered by disease, organisations matched to ROR.

Terminated, withdrawn and suspended trials with the reason the sponsor gave in the registry, quoted word for word.

• Terminated

  Neoadjuvant Durvalumab and Tremelimumab Plus Radiation for High Risk Soft-Tissue Sarcoma

  NCT03116529· University of Maryland, Baltimore· Updated 5 Nov 2026

  “Limited Accrual”Registry text, quoted unchanged. Source

• Suspended

  Novel RNA-lipid Particle (RNA-LP) Vaccine for Anti-PD-1 Antibody Therapy Sensitization

  NCT05264974· University of Florida· Updated 17 Sept 2026

  “seeking additional funding”Registry text, quoted unchanged. Source

• Terminated

  A Study of XmAb23104 in People With Sarcoma

  NCT05879185· Memorial Sloan Kettering Cancer Center· Updated 13 Apr 2026

  “Vendor decided study to be closed early”Registry text, quoted unchanged. Source

• Terminated

  Nivolumab and Ipilimumab in Treating Patients With HIV Associated Relapsed or Refractory Classical Hodgkin Lymphoma or Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery

  NCT02408861· National Cancer Institute (NCI)· Updated 21 Jan 2026

  “Inadequate accrual rate”Registry text, quoted unchanged. Source

• Terminated

  A Study to Evaluate the Safety and Pharmacokinetics of OC-001 in Patients With Locally Advanced or Metastatic Cancers

  NCT04260802· Ocellaris Pharma, Inc.· Updated 12 Jan 2026

  “Business Decision”Registry text, quoted unchanged. Source

• Terminated

  A Study of FAZ053 Single Agent and in Combination With PDR001 in Patients With Advanced Malignancies.

  NCT02936102· Novartis Pharmaceuticals· Updated 14 Nov 2025

  “The early termination was based on a business decision that FAZ053 would no longer be formulated and was not a consequence of any safety concern.”Registry text, quoted unchanged. Source

• Withdrawn

  Targeting MDMD and PD1 in Tumors With Tertiary Lymphoid Structures

  NCT06084689· Institut Bergonié· Updated 2 Sept 2025

  “Discontinuation of molecule development”Registry text, quoted unchanged. Source

• Terminated

  Surufatinib in Combination With Tislelizumab in Subjects With Advanced Solid Tumors

  NCT04579757· Hutchmed· Updated 8 May 2025

  “Study terminated by sponsor”Registry text, quoted unchanged. Source

• Withdrawn

  Regorafenib With Tislelizumab in Patients With Selected Mismatch Repair-Proficient/Microsatellite Stable Cancers

  NCT05582031· Translational Research in Oncology· Updated 7 Jun 2023

  “Study never started/ will not proceed.”Registry text, quoted unchanged. Source

Trials whose registry record says individual participant data (IPD) will be shared.

• A Study of Calderasib (MK-1084) Plus Pembrolizumab (MK-3475) in Participants With KRAS G12C Mutant Non-small Cell Lung Cancer (NSCLC) With Programmed Cell Death Ligand 1 (PD-L1) Tumor Proportion Score (TPS) ≥50% (MK-1084-004/KANDLELIT-004)

  NCT06345729· Merck Sharp & Dohme LLC· Source

• KEYMAKER-U01 Substudy 01J: A Study of Pembrolizumab Plus MK-1084 in Participants With Non-Small Cell Lung Cancer (NSCLC) With Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) G12C Mutations (MK-3475-01J/KEYMAKER-U01J)

  NCT07252739· Merck Sharp & Dohme LLC· Source

• A Study of Therapeutic Drug Monitoring-Based Atezolizumab Dosing

  NCT06066138· National Cancer Institute (NCI)· Source

• EWSR1 Immunotherapy in Ewing Sarcoma and DSRCT

  NCT07695311· Rabi Hanna· Source

• Palbociclib and INCMGA00012 in People With Advanced Liposarcoma

  NCT04438824· Memorial Sloan Kettering Cancer Center· Source

• Retifanlimab (Anti-PD-1 Antibody) With Gemcitabine and Docetaxel in Patients With Advanced Soft Tissue Sarcoma

  NCT04577014· Memorial Sloan Kettering Cancer Center· Source

• A Study of XmAb23104 in People With Sarcoma

  NCT05879185· Memorial Sloan Kettering Cancer Center· Source

Find publications on this disease by a MeSH method term, for example a sequencing or imaging method.

• Single-Cell Analysis 41
• Organoids 10
• Mendelian Randomization Analysis 2
• CRISPR-Cas Systems 11
• Gene Expression Profiling 99
• Sequence Analysis, RNA 21
• Whole Genome Sequencing 4
• Exome Sequencing 14
• Proteomics 31
• Metabolomics 7
• Mass Spectrometry 5
• Flow Cytometry 52
• Immunohistochemistry 186
• Liquid Biopsy 12
• Circulating Tumor DNA 19
• Xenograft Model Antitumor Assays 152
• Positron-Emission Tomography 19
• Magnetic Resonance Imaging 197
• Machine Learning 28
• Deep Learning 16
• Cohort Studies 30
• Genome-Wide Association Study 2

• Preclinical evaluation of 68Ga-labelled Pt(IV)-DFO complexes as PET-imaging agents for osteosarcoma.

  Eur J Med Chem, Sept 2026

• Omitting Bone Marrow Sampling in FDG-Avid Rhabdomyosarcoma With 2-[18F]FDG PET-Negative Marrow: Results From an International Retrospective Study.

  J Clin Oncol, Aug 2026

• PET radiotracers targeting MDM2 protein interaction: From preclinical validation to first-in-human studies.

  Pharmacol Res, Jun 2026

• Evaluation of standardized uptake value (SUV) and apparent diffusion coefficient (ADC) as prognostic imaging parameters for primary Ewing sarcoma in hybrid 18F-FDG-PET/MRI.

  Eur J Radiol, Jun 2026

• Diagnostic value of integrated 18 F-fluorodeoxyglucose PET/MRI in initial staging and recurrence detection of Ewing sarcoma.

  Nucl Med Commun, Jun 2026

• Current Practices and Variations in the Use of FDG-PET and Bone Marrow Biopsy in Ewing Sarcoma Diagnosis: A Survey of Provider Recommendations.

  J Pediatr Hematol Oncol, Jun 2026

• Mucoid impaction presenting as a solitary pulmonary mass mimicking lung malignancy.

  BMJ Case Rep, Jun 2026

• Role of diffusion-weighted MRI in assessing Ewing sarcoma treatment response: Findings from a COG phase III trial.

  Magn Reson Imaging, May 2026

• Mass Dose Effects in FAP-Directed Imaging: Influence of Administered Dose of [68Ga]Ga-LNTH-1363S on Image Quality.

  J Nucl Med, Apr 2026

• Synthesis and evaluation of RG7388-based fluorinated MDM2 inhibitors for developing 18F-labeled probes for PET imaging.

  Eur J Med Chem, Mar 2026

See which targets of this disease your abstract mentions, and go to the people working on them.